Best TWAS P=1.86e-11 · Best GWAS P=7.03e-15 conditioned to 0.299
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | WARS2 | 0.28 | 0.15 | enet | 13 | 0.25 | 1.1e-06 | 2.1 | -5.2 | 2.1e-07 | 0.84 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Brain Nucleus accumbens basal ganglia | WARS2 | 0.40 | 0.18 | enet | 10 | 0.23 | 9.2e-07 | 4.1 | -5.2 | 1.5e-07 | 0.79 | 0.01 | 0.96 | FALSE |
| 3 | GTEx | Testis | WARS2 | 0.25 | 0.17 | lasso | 3 | 0.17 | 4.3e-08 | 5.1 | 5.8 | 5.4e-09 | -0.46 | 0.83 | 0.08 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TBX15 | 0.07 | 0.02 | blup | 92 | 0.05 | 2.2e-06 | 6.8 | 6.7 | 1.9e-11 | -0.67 | 0.10 | 0.89 | TRUE |