[Hub]/) : Traits : Impedance of leg (right) : ← →

chr1:149,672,809-152,126,467

Best TWAS P=5.63e-13 · Best GWAS P=1.29e-09 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ARNT	0.23	0.30	lasso	6	0.30	1.1e-37	-4.97	-5.2	2.2e-07	-0.01	0.74	0.26	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CERS2	0.04	0.03	bslmm	307	0.02	1.7e-03	-4.68	-5.7	1.1e-08	0.03	0.54	0.24	FALSE
3	CommonMind	Brain Pre-frontal Cortex	CTSS	0.04	0.01	bslmm	313	0.02	5.5e-04	5.85	-7.2	5.6e-13	0.13	0.03	0.94	TRUE
4	CommonMind	Brain Pre-frontal Cortex	GABPB2	0.05	0.01	blup	324	0.01	1.6e-02	0.74	5.4	6.2e-08	0.08	0.09	0.32	FALSE
5	CommonMind	Brain Pre-frontal Cortex	MRPS21	0.06	0.04	lasso	7	0.04	5.7e-06	-5.08	-5.2	1.6e-07	0.15	0.39	0.52	FALSE
6	GTEx	Adipose Subcutaneous	TARS2	0.06	0.02	enet	8	0.03	2.2e-03	-5.11	5.8	5.8e-09	-0.04	0.08	0.86	FALSE
7	GTEx	Adipose Subcutaneous	SEMA6C	0.12	0.11	lasso	2	0.11	1.8e-09	5.73	5.7	9.6e-09	-0.18	0.02	0.98	FALSE
8	GTEx	Adrenal Gland	CTSS	0.12	0.13	lasso	9	0.08	7.0e-04	-5.22	-5.2	2.6e-07	0.00	0.30	0.61	FALSE
9	GTEx	Artery Aorta	RPRD2	0.08	-0.01	enet	19	0.00	4.2e-01	-4.90	7.1	1.2e-12	0.30	0.05	0.54	FALSE
10	GTEx	Artery Tibial	RP11-196G18.22	0.25	0.05	lasso	5	0.07	1.8e-06	5.92	5.2	1.6e-07	0.78	0.01	0.99	TRUE
11	GTEx	Brain Cerebellum	CTSS	0.23	0.02	enet	25	0.07	5.0e-03	-4.91	-5.6	1.8e-08	-0.05	0.08	0.80	FALSE
12	GTEx	Brain Hippocampus	ARNT	0.14	0.09	enet	14	0.08	5.3e-03	-4.90	-6.5	1.0e-10	0.00	0.05	0.58	TRUE
13	GTEx	Breast Mammary Tissue	TARS2	0.18	0.05	lasso	3	0.07	2.5e-04	-5.00	5.3	1.4e-07	-0.03	0.35	0.32	FALSE
14	GTEx	Breast Mammary Tissue (Male)	RP11-54A4.2	0.07	0.01	enet	2	0.03	7.4e-02	5.54	5.7	1.5e-08	0.08	0.04	0.18	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	CTSS	0.28	0.22	lasso	8	0.30	3.0e-10	-5.00	-5.4	6.7e-08	0.03	0.52	0.48	FALSE
16	GTEx	Cells Transformed fibroblasts	ARNT	0.10	0.09	enet	27	0.08	1.8e-06	-4.99	-5.9	3.2e-09	0.01	0.17	0.83	FALSE
17	GTEx	Esophagus Mucosa	CTSS	0.10	0.10	enet	10	0.06	6.8e-05	-5.00	-5.3	9.2e-08	-0.01	0.12	0.88	FALSE
18	GTEx	Esophagus Muscularis	BOLA1	0.07	0.00	lasso	4	0.00	2.5e-01	-3.61	5.7	1.2e-08	0.43	0.03	0.22	FALSE
19	GTEx	Muscle Skeletal	CTSS	0.04	0.01	enet	13	0.03	1.4e-03	-6.05	-6.4	1.3e-10	-0.01	0.08	0.85	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	SEMA6C	0.13	0.10	lasso	4	0.07	7.4e-05	5.71	5.3	1.1e-07	-0.18	0.01	0.99	FALSE
21	GTEx	Skin Sun Exposed Lower leg	SEMA6C	0.10	0.07	lasso	5	0.04	2.6e-04	5.71	5.4	5.6e-08	-0.19	0.01	0.99	TRUE
22	GTEx	Spleen	RP11-54A4.2	0.29	0.10	lasso	9	0.04	3.8e-02	-5.22	5.6	2.4e-08	0.04	0.28	0.13	FALSE
23	GTEx	Testis	CTSK	0.07	0.01	enet	19	0.01	1.2e-01	-3.81	-5.3	9.5e-08	-0.03	0.30	0.23	FALSE
24	GTEx	Testis	RPRD2	0.33	0.13	lasso	7	0.19	9.1e-09	-5.11	5.8	9.0e-09	-0.04	0.56	0.39	FALSE
25	GTEx	Thyroid	ANP32E	0.08	0.00	enet	15	0.01	8.6e-02	-5.69	5.4	5.9e-08	0.37	0.04	0.18	FALSE
26	GTEx	Thyroid	ARNT	0.08	0.10	lasso	10	0.10	7.8e-08	5.27	-5.9	3.2e-09	-0.05	0.05	0.95	FALSE
27	GTEx	Thyroid	CTSS	0.15	0.12	enet	30	0.18	2.4e-13	-3.87	-5.1	3.0e-07	0.02	0.99	0.01	FALSE
28	METSIM	Adipose	POGZ	0.06	0.05	lasso	12	0.03	9.3e-06	-4.78	-5.5	3.3e-08	-0.05	0.84	0.15	FALSE
29	METSIM	Adipose	RPRD2	0.04	0.02	enet	24	0.03	2.1e-05	3.53	5.4	5.4e-08	-0.01	0.79	0.06	FALSE
30	METSIM	Adipose	TARS2	0.09	0.09	enet	8	0.08	1.6e-12	-5.00	5.4	6.1e-08	-0.11	0.13	0.87	FALSE
31	METSIM	Adipose	TMOD4	0.02	0.00	blup	312	0.01	3.2e-02	-5.62	6.1	9.6e-10	0.11	0.08	0.07	FALSE
32	YFS	Blood	CTSS	0.17	0.11	enet	42	0.17	4.2e-52	-4.04	-5.3	9.5e-08	0.09	0.99	0.01	FALSE
33	YFS	Blood	PRPF3	0.01	0.01	enet	16	0.01	4.6e-05	3.67	5.4	5.7e-08	0.04	0.48	0.04	FALSE
34	YFS	Blood	SCNM1	0.09	0.04	enet	62	0.08	1.3e-24	-3.73	6.4	1.4e-10	0.05	0.99	0.00	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1orf54	0.06	0.02	enet	13	0.02	1.2e-05	-5.89	5.6	2.7e-08	-0.15	0.03	0.82	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1orf54	0.04	0.04	lasso	2	0.03	2.0e-04	-5.89	5.9	3.2e-09	-0.10	0.04	0.87	TRUE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1orf54	0.06	0.03	lasso	1	0.03	1.3e-04	-5.89	5.9	3.9e-09	-0.10	0.02	0.57	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMB4	0.03	0.00	blup	37	0.02	7.0e-03	-4.78	6.1	1.4e-09	0.13	0.01	0.74	TRUE
39	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARNT	0.11	0.08	blup	45	0.08	3.2e-09	-4.97	-5.3	1.1e-07	0.02	0.00	0.99	FALSE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	RPRD2	0.03	0.01	blup	19	0.02	2.6e-03	-4.79	5.3	1.1e-07	-0.02	0.01	0.84	TRUE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	SV2A	0.04	0.00	blup	9	0.03	5.5e-04	-5.73	-6.5	1.1e-10	-0.21	0.00	0.49	TRUE
42	The Cancer Genome Atlas	Lung Adenocarcinoma	ADAMTSL4	0.02	0.00	blup	33	0.02	4.7e-03	1.49	-5.7	1.4e-08	0.04	0.02	0.18	FALSE
43	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MRPS21	0.04	0.03	blup	15	0.04	4.0e-05	2.91	-6.2	7.5e-10	0.02	0.05	0.49	TRUE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1orf54	0.09	0.00	blup	17	0.03	7.4e-04	4.37	5.7	1.2e-08	-0.11	0.02	0.26	FALSE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	ENSA	0.02	0.01	enet	3	0.01	2.5e-02	-5.78	6.7	2.2e-11	0.08	0.01	0.70	FALSE
46	The Cancer Genome Atlas	Prostate Adenocarcinoma	SF3B4	0.03	0.02	blup	10	0.01	1.4e-02	-4.84	-6.1	1.2e-09	-0.32	0.04	0.30	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	SELENBP1	0.06	0.02	enet	7	0.05	2.3e-05	-4.78	-5.6	1.8e-08	-0.13	0.00	0.98	FALSE