[Hub]/) : Traits : Impedance of leg (right) :

chr11:94,805,896-96,261,289

Best TWAS P=7.61e-08 · Best GWAS P=1.37e-07 conditioned to 0.404

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM76B 0.06 0.02 lasso 3 0.01 8.1e-03 -5.1 5.3 9.0e-08 0.80 0.03 0.96 FALSE
2 GTEx Brain Cerebellar Hemisphere AP001877.1 0.29 0.24 lasso 7 0.25 5.0e-07 -5.1 -5.3 1.3e-07 -0.85 0.03 0.97 FALSE
3 GTEx Colon Transverse CEP57 0.12 0.11 lasso 3 0.11 6.8e-06 -5.1 -5.2 1.7e-07 -0.83 0.04 0.96 FALSE
4 GTEx Esophagus Mucosa CEP57 0.14 0.14 lasso 3 0.10 6.0e-07 -5.1 -5.1 3.1e-07 -0.83 0.03 0.97 FALSE
5 GTEx Esophagus Muscularis CEP57 0.15 0.05 enet 21 0.06 9.0e-05 -5.1 -5.2 1.9e-07 -0.81 0.03 0.97 FALSE
6 GTEx Esophagus Muscularis AP001877.1 0.17 0.09 lasso 6 0.10 6.2e-07 -5.1 -5.4 7.6e-08 -0.92 0.04 0.96 TRUE
7 GTEx Liver FAM76B 0.43 0.08 enet 32 0.13 1.4e-04 -5.2 -5.3 1.3e-07 -0.64 0.03 0.93 FALSE
8 GTEx Liver CEP57 0.24 0.10 enet 23 0.01 2.1e-01 -5.1 -5.3 1.4e-07 -0.73 0.04 0.82 FALSE
9 GTEx Lung CEP57 0.12 0.05 enet 16 0.04 4.4e-04 -5.1 -5.4 8.7e-08 -0.76 0.03 0.97 FALSE
10 GTEx Muscle Skeletal CEP57 0.15 0.18 lasso 9 0.18 1.8e-17 -5.2 -5.1 2.8e-07 -0.79 0.02 0.97 FALSE
11 GTEx Nerve Tibial CEP57 0.15 0.08 lasso 6 0.07 1.9e-05 -5.1 -5.3 1.5e-07 -0.83 0.03 0.97 FALSE
12 GTEx Pancreas CEP57 0.19 0.10 lasso 13 0.08 3.6e-04 -5.1 -5.4 8.5e-08 -0.79 0.03 0.96 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic CEP57 0.14 0.06 enet 10 0.05 9.6e-04 -3.9 -5.1 3.0e-07 -0.73 0.03 0.96 FALSE
14 GTEx Skin Sun Exposed Lower leg CEP57 0.19 0.14 enet 24 0.16 4.1e-13 -5.1 -5.3 1.4e-07 -0.89 0.03 0.97 FALSE
15 GTEx Small Intestine Terminal Ileum AP001877.1 0.34 0.14 lasso 22 0.11 1.8e-03 -5.1 -5.2 2.2e-07 -0.70 0.03 0.87 FALSE
16 ROSMAP Brain Pre-frontal Cortex AP001877.1 0.17 0.27 lasso 12 0.27 3.6e-35 -5.2 -5.2 2.0e-07 -0.76 0.03 0.97 FALSE
17 YFS Blood FAM76B 0.14 0.25 lasso 10 0.26 8.1e-83 -5.2 5.2 1.7e-07 0.75 0.03 0.97 FALSE