Best TWAS P=5.34e-11 · Best GWAS P=7.28e-12 conditioned to 0.0188
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | DNAJC3 | 0.10 | 0.06 | lasso | 7 | 0.05 | 1.8e-03 | -5.5 | 6.6 | 5.3e-11 | -0.86 | 0.02 | 0.93 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HS6ST3 | 0.06 | 0.03 | blup | 307 | 0.03 | 7.4e-05 | 4.1 | -5.2 | 2.4e-07 | 0.72 | 0.06 | 0.82 | FALSE |