TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of leg (right)
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chr13:95,632,770-97,735,785
Best TWAS P=5.34e-11 · Best GWAS P=7.28e-12 conditioned to 0.0188
96M
96.5M
97M
97.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Colon Transverse
DNAJC3
0.10
0.06
lasso
7
0.05
1.8e-03
-5.5
6.6
5.3e-11
-0.86
0.02
0.93
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
HS6ST3
0.06
0.03
blup
307
0.03
7.4e-05
4.1
-5.2
2.4e-07
0.72
0.06
0.82
FALSE