Best TWAS P=1.17e-21 · Best GWAS P=1.79e-20 conditioned to 0.118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | 7.5 | -7.6 | 2.3e-14 | -0.61 | 0.4 | 0.57 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | 9.3 | -9.6 | 1.2e-21 | -0.90 | 0.0 | 0.78 | TRUE |