TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of leg (right)
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chr14:59,862,624-61,328,990
Best TWAS P=1.31e-10 · Best GWAS P=9.78e-10 conditioned to 0.00536
59.8M
60M
60.2M
60.4M
60.6M
60.8M
61M
61.2M
61.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Not Sun Exposed Suprapubic
PCNXL4
0.15
0.05
enet
15
0.12
6.2e-07
-3.4
6.4
1.3e-10
-0.61
0.28
0.67
TRUE