Best TWAS P=4.87e-08 · Best GWAS P=1.66e-06 conditioned to 0.000449
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Liver | WWOX | 0.49 | 0.00 | enet | 16 | 0.02 | 8.2e-02 | 4.2 | -5.5 | 4.9e-08 | 0.26 | 0.06 | 0.16 | TRUE |
2 | METSIM | Adipose | WWOX | 0.31 | 0.07 | enet | 69 | 0.17 | 4.8e-25 | -2.7 | -5.2 | 2.1e-07 | 0.10 | 0.18 | 0.45 | FALSE |