Best TWAS P=1.9e-10 · Best GWAS P=2.41e-11 conditioned to 6.95e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | REXO1 | 0.07 | 0.01 | bslmm | 391 | 0.01 | 1.7e-02 | 3.6 | -6.4 | 1.9e-10 | 0.51 | 0.09 | 0.70 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | KLF16 | 0.12 | 0.08 | bslmm | 372 | 0.08 | 1.0e-10 | 6.6 | 5.9 | 4.7e-09 | -0.85 | 0.00 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ATP8B3 | 0.04 | 0.01 | blup | 49 | 0.02 | 2.2e-03 | 6.6 | 5.9 | 4.9e-09 | -0.85 | 0.00 | 0.76 | FALSE |