[Hub]/) : Traits : Impedance of leg (right) : ← →

chr19:3,268,722-5,153,606

Best TWAS P=6.17e-14 · Best GWAS P=4.42e-12 conditioned to 0.00403

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	UBXN6	0.10	0.00	enet	21	0.02	8.0e-03	6.6	5.2	2.2e-07	-0.40	0.01	0.95	FALSE
2	GTEx	Artery Aorta	UBXN6	0.13	0.02	lasso	5	0.03	5.7e-03	6.6	6.7	2.5e-11	-0.32	0.01	0.98	FALSE
3	GTEx	Artery Tibial	UBXN6	0.18	0.07	lasso	3	0.14	6.3e-11	-4.5	6.0	1.5e-09	-0.31	0.02	0.98	FALSE
4	GTEx	Brain Caudate basal ganglia	CTB-50L17.9	0.27	0.25	lasso	2	0.24	1.8e-07	-5.2	5.5	3.1e-08	-0.14	0.27	0.37	FALSE
5	GTEx	Brain Cerebellar Hemisphere	CHAF1A	0.62	0.40	lasso	8	0.36	3.5e-10	-5.2	5.2	2.4e-07	-0.13	0.93	0.05	FALSE
6	GTEx	Brain Cerebellum	CTB-50L17.9	0.53	0.41	lasso	2	0.50	3.6e-17	-4.4	5.3	1.1e-07	-0.17	0.87	0.13	FALSE
7	GTEx	Brain Frontal Cortex BA9	CTB-50L17.9	0.27	0.21	lasso	3	0.19	7.9e-06	-4.4	5.1	2.9e-07	-0.16	0.17	0.68	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	CTB-50L17.9	0.45	0.25	lasso	8	0.23	8.6e-07	-5.2	6.8	1.3e-11	-0.23	0.06	0.90	FALSE
9	GTEx	Cells Transformed fibroblasts	UBXN6	0.09	0.10	lasso	1	0.08	1.5e-06	6.6	6.6	4.4e-11	-0.38	0.00	0.99	FALSE
10	GTEx	Heart Atrial Appendage	UBXN6	0.34	0.12	lasso	6	0.21	6.5e-10	-5.2	6.4	2.0e-10	-0.30	0.01	0.99	FALSE
11	GTEx	Heart Left Ventricle	CHAF1A	0.17	0.12	lasso	2	0.11	1.9e-06	-5.2	5.2	1.8e-07	-0.14	0.79	0.07	FALSE
12	GTEx	Heart Left Ventricle	UBXN6	0.21	0.14	lasso	6	0.16	5.6e-09	6.6	6.8	1.3e-11	-0.36	0.01	0.99	FALSE
13	GTEx	Muscle Skeletal	UBXN6	0.19	0.14	lasso	5	0.18	4.1e-17	6.6	6.9	5.7e-12	-0.32	0.00	1.00	FALSE
14	GTEx	Prostate	MIR637	0.30	-0.01	lasso	6	-0.01	5.5e-01	6.6	5.3	1.2e-07	-0.33	0.02	0.56	FALSE
15	GTEx	Stomach	AC007292.4	0.27	0.09	lasso	5	0.04	4.0e-03	6.4	-6.1	1.4e-09	0.44	0.02	0.86	FALSE
16	GTEx	Whole Blood	UBXN6	0.06	0.03	lasso	4	0.01	4.1e-02	6.4	5.8	5.8e-09	-0.42	0.01	0.97	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	UBXN6	0.03	0.03	lasso	3	0.03	2.3e-06	6.6	6.8	1.4e-11	-0.41	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	SEMA6B	0.24	-0.01	blup	42	0.05	1.1e-02	-4.8	-5.3	1.1e-07	0.60	0.00	0.39	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UBXN6	0.05	0.01	blup	57	0.04	6.6e-05	-5.2	7.5	6.2e-14	-0.62	0.06	0.83	TRUE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBXN6	0.13	0.10	lasso	2	0.10	1.3e-10	-5.2	5.7	1.3e-08	-0.20	0.98	0.02	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	UBXN6	0.16	0.12	lasso	2	0.12	5.4e-12	-5.2	5.6	2.1e-08	-0.17	0.97	0.03	FALSE