[Hub]/) : Traits : Impedance of leg (right) :

chr19:3,268,722-5,153,606

Best TWAS P=6.17e-14 · Best GWAS P=4.42e-12 conditioned to 0.00403

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous UBXN6 0.10 0.00 enet 21 0.02 8.0e-03 6.6 5.2 2.2e-07 -0.40 0.01 0.95 FALSE
2 GTEx Artery Aorta UBXN6 0.13 0.02 lasso 5 0.03 5.7e-03 6.6 6.7 2.5e-11 -0.32 0.01 0.98 FALSE
3 GTEx Artery Tibial UBXN6 0.18 0.07 lasso 3 0.14 6.3e-11 -4.5 6.0 1.5e-09 -0.31 0.02 0.98 FALSE
4 GTEx Brain Caudate basal ganglia CTB-50L17.9 0.27 0.25 lasso 2 0.24 1.8e-07 -5.2 5.5 3.1e-08 -0.14 0.27 0.37 FALSE
5 GTEx Brain Cerebellar Hemisphere CHAF1A 0.62 0.40 lasso 8 0.36 3.5e-10 -5.2 5.2 2.4e-07 -0.13 0.93 0.05 FALSE
6 GTEx Brain Cerebellum CTB-50L17.9 0.53 0.41 lasso 2 0.50 3.6e-17 -4.4 5.3 1.1e-07 -0.17 0.87 0.13 FALSE
7 GTEx Brain Frontal Cortex BA9 CTB-50L17.9 0.27 0.21 lasso 3 0.19 7.9e-06 -4.4 5.1 2.9e-07 -0.16 0.17 0.68 FALSE
8 GTEx Brain Nucleus accumbens basal ganglia CTB-50L17.9 0.45 0.25 lasso 8 0.23 8.6e-07 -5.2 6.8 1.3e-11 -0.23 0.06 0.90 FALSE
9 GTEx Cells Transformed fibroblasts UBXN6 0.09 0.10 lasso 1 0.08 1.5e-06 6.6 6.6 4.4e-11 -0.38 0.00 0.99 FALSE
10 GTEx Heart Atrial Appendage UBXN6 0.34 0.12 lasso 6 0.21 6.5e-10 -5.2 6.4 2.0e-10 -0.30 0.01 0.99 FALSE
11 GTEx Heart Left Ventricle CHAF1A 0.17 0.12 lasso 2 0.11 1.9e-06 -5.2 5.2 1.8e-07 -0.14 0.79 0.07 FALSE
12 GTEx Heart Left Ventricle UBXN6 0.21 0.14 lasso 6 0.16 5.6e-09 6.6 6.8 1.3e-11 -0.36 0.01 0.99 FALSE
13 GTEx Muscle Skeletal UBXN6 0.19 0.14 lasso 5 0.18 4.1e-17 6.6 6.9 5.7e-12 -0.32 0.00 1.00 FALSE
14 GTEx Prostate MIR637 0.30 -0.01 lasso 6 -0.01 5.5e-01 6.6 5.3 1.2e-07 -0.33 0.02 0.56 FALSE
15 GTEx Stomach AC007292.4 0.27 0.09 lasso 5 0.04 4.0e-03 6.4 -6.1 1.4e-09 0.44 0.02 0.86 FALSE
16 GTEx Whole Blood UBXN6 0.06 0.03 lasso 4 0.01 4.1e-02 6.4 5.8 5.8e-09 -0.42 0.01 0.97 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma UBXN6 0.03 0.03 lasso 3 0.03 2.3e-06 6.6 6.8 1.4e-11 -0.41 0.02 0.98 FALSE
18 The Cancer Genome Atlas Glioblastoma Multiforme SEMA6B 0.24 -0.01 blup 42 0.05 1.1e-02 -4.8 -5.3 1.1e-07 0.60 0.00 0.39 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma UBXN6 0.05 0.01 blup 57 0.04 6.6e-05 -5.2 7.5 6.2e-14 -0.62 0.06 0.83 TRUE
20 The Cancer Genome Atlas Prostate Adenocarcinoma UBXN6 0.13 0.10 lasso 2 0.10 1.3e-10 -5.2 5.7 1.3e-08 -0.20 0.98 0.02 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma UBXN6 0.16 0.12 lasso 2 0.12 5.4e-12 -5.2 5.6 2.1e-08 -0.17 0.97 0.03 FALSE