Best TWAS P=3.39e-09 · Best GWAS P=1.54e-07 conditioned to 0.424
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HHATL | 0.25 | 0.22 | lasso | 8 | 0.27 | 5.5e-33 | -5.0 | -5.4 | 7.1e-08 | 0.90 | 0.01 | 0.99 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | HHATL | 0.21 | 0.15 | bslmm | 465 | 0.18 | 1.3e-22 | 3.7 | -5.9 | 3.4e-09 | 0.79 | 0.43 | 0.46 | TRUE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ULK4 | 0.14 | 0.06 | enet | 24 | 0.10 | 1.6e-04 | -3.6 | -5.2 | 1.8e-07 | 0.02 | 0.06 | 0.68 | TRUE |