TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (right)
:
←
→
chr3:41,042,846-43,440,106
Best TWAS P=3.39e-09 · Best GWAS P=1.54e-07 conditioned to 0.424
41M
41.5M
42M
42.5M
43M
43.5M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
HHATL
0.21
0.15
bslmm
465
0.18
1.3e-22
3.7
-5.9
3.4e-09
0.79
0.43
0.46
TRUE
3
The Cancer Genome Atlas
Testicular Germ Cell Tumors
ULK4
0.14
0.06
enet
24
0.10
1.6e-04
-3.6
-5.2
1.8e-07
0.02
0.06
0.68
TRUE
1
CommonMind
Brain Pre-frontal Cortex
HHATL
0.25
0.22
lasso
8
0.27
5.5e-33
-5.0
-5.4
7.1e-08
0.90
0.01
0.99
FALSE