TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (right)
:
←
→
chr3:84,317,575-86,808,226
Best TWAS P=2.41e-11 · Best GWAS P=1.96e-12 conditioned to 0.00603
84.5M
85M
85.5M
86M
86.5M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
CADM2
0.05
0.03
lasso
3
0.04
5.0e-05
-6.5
-6.7
2.4e-11
0.82
0.13
0.86
TRUE
2
The Cancer Genome Atlas
Lung Adenocarcinoma
CADM2
0.08
0.04
lasso
4
0.05
2.1e-06
-6.5
-6.5
6.1e-11
0.77
0.24
0.75
FALSE
1
METSIM
Adipose
CADM2
0.05
0.06
lasso
10
0.06
1.3e-09
-5.9
-6.4
1.6e-10
0.63
0.79
0.21
FALSE