Best TWAS P=2.41e-11 · Best GWAS P=1.96e-12 conditioned to 0.00603
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | -5.9 | -6.4 | 1.6e-10 | 0.63 | 0.79 | 0.21 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | -6.5 | -6.5 | 6.1e-11 | 0.77 | 0.24 | 0.75 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | -6.5 | -6.7 | 2.4e-11 | 0.82 | 0.13 | 0.86 | TRUE |