Best TWAS P=3.07e-09 · Best GWAS P=3.63e-08 conditioned to 0.0301
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CLOCK | 0.19 | 0.09 | lasso | 6 | 0.11 | 2.0e-08 | -3.4 | 5.9 | 3.1e-09 | 0.65 | 0.29 | 0.70 | TRUE |
| 2 | GTEx | Lung | CLOCK | 0.07 | 0.02 | lasso | 4 | 0.03 | 3.0e-03 | -3.3 | 5.2 | 2.6e-07 | 0.79 | 0.03 | 0.93 | FALSE |
| 3 | GTEx | Thyroid | CLOCK | 0.16 | 0.14 | enet | 46 | 0.14 | 9.5e-11 | 5.5 | 5.7 | 1.1e-08 | 0.82 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CLOCK | 0.08 | 0.07 | enet | 9 | 0.06 | 4.5e-05 | 5.5 | 5.7 | 1.2e-08 | 0.99 | 0.01 | 0.97 | FALSE |