TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
:
Impedance of leg (right)
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chr4:55,598,706-57,110,821
Best TWAS P=3.07e-09 · Best GWAS P=3.63e-08 conditioned to 0.0301
55.6M
55.8M
56M
56.2M
56.4M
56.6M
56.8M
57M
57.2M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
CLOCK
0.19
0.09
lasso
6
0.11
2.0e-08
-3.4
5.9
3.1e-09
0.65
0.29
0.70
TRUE
3
GTEx
Thyroid
CLOCK
0.16
0.14
enet
46
0.14
9.5e-11
5.5
5.7
1.1e-08
0.82
0.01
0.99
FALSE
4
The Cancer Genome Atlas
Stomach Adenocarcinoma
CLOCK
0.08
0.07
enet
9
0.06
4.5e-05
5.5
5.7
1.2e-08
0.99
0.01
0.97
FALSE
2
GTEx
Lung
CLOCK
0.07
0.02
lasso
4
0.03
3.0e-03
-3.3
5.2
2.6e-07
0.79
0.03
0.93
FALSE