Best TWAS P=1.35e-07 · Best GWAS P=2.14e-08 conditioned to 0.000333
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | MMRN1 | 0.28 | 0.22 | bslmm | 395 | 0.22 | 1.1e-27 | 4.8 | 5.3 | 1.4e-07 | 0.46 | 0.24 | 0.75 | TRUE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | MMRN1 | 0.24 | 0.12 | lasso | 2 | 0.11 | 8.2e-05 | 5.3 | 5.1 | 2.9e-07 | 0.43 | 0.01 | 0.91 | FALSE |