Best TWAS P=3.55e-09 · Best GWAS P=1.1e-08 conditioned to 0.0792
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | DNAJB14 | 0.24 | 0.18 | lasso | 4 | 0.14 | 1.4e-05 | -5.6 | -5.4 | 7.5e-08 | 0.97 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Artery Aorta | DNAJB14 | 0.24 | 0.01 | lasso | 13 | 0.09 | 8.1e-06 | -2.9 | -5.3 | 1.2e-07 | 0.82 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Artery Tibial | DNAJB14 | 0.11 | 0.01 | enet | 15 | 0.05 | 1.2e-04 | -5.5 | -5.5 | 3.0e-08 | 0.75 | 0.02 | 0.96 | FALSE |
| 4 | GTEx | Whole Blood | DAPP1 | 0.06 | 0.03 | enet | 15 | 0.01 | 1.8e-02 | 2.6 | 5.9 | 3.5e-09 | -0.27 | 0.18 | 0.44 | TRUE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DNAJB14 | 0.03 | 0.01 | lasso | 4 | 0.01 | 1.8e-03 | -5.7 | -5.6 | 1.8e-08 | 0.93 | 0.00 | 0.98 | TRUE |