[Hub]/) : Traits : Impedance of leg (right) : ← →

chr6:129,638,583-131,163,098

Best TWAS P=9.68e-11 · Best GWAS P=3.53e-09 conditioned to 0.705

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	L3MBTL3	0.20	0.08	lasso	4	0.09	1.1e-07	-4.7	-5.7	1.1e-08	0.89	0.08	0.92	FALSE
2	GTEx	Adipose Visceral Omentum	L3MBTL3	0.14	0.12	lasso	2	0.15	2.8e-08	-4.7	-5.5	4.6e-08	0.90	0.02	0.97	FALSE
3	GTEx	Breast Mammary Tissue	L3MBTL3	0.31	0.25	lasso	7	0.23	2.8e-12	-4.7	-5.3	1.2e-07	0.89	0.04	0.96	FALSE
4	GTEx	Breast Mammary Tissue	RP11-73O6.3	0.27	0.22	lasso	9	0.22	1.5e-11	-4.7	-5.1	3.0e-07	0.85	0.16	0.84	FALSE
5	GTEx	Breast Mammary Tissue (Male)	L3MBTL3	0.31	0.24	lasso	6	0.23	5.5e-06	-4.7	-5.3	1.2e-07	0.91	0.02	0.91	FALSE
6	GTEx	Breast Mammary Tissue (Female)	L3MBTL3	0.30	0.13	lasso	5	0.14	4.5e-05	-3.4	-5.1	2.8e-07	0.86	0.02	0.95	FALSE
7	GTEx	Breast Mammary Tissue (Female)	RP11-73O6.3	0.29	0.08	lasso	5	0.10	5.7e-04	-4.7	-5.3	1.2e-07	0.85	0.02	0.92	FALSE
8	GTEx	Colon Transverse	L3MBTL3	0.27	0.13	lasso	8	0.20	8.0e-10	-4.7	-5.6	2.0e-08	0.87	0.02	0.98	FALSE
9	GTEx	Lung	L3MBTL3	0.37	0.34	lasso	4	0.38	4.1e-30	-4.7	-5.4	5.1e-08	0.89	0.34	0.66	FALSE
10	GTEx	Lung	RP11-73O6.3	0.15	0.08	lasso	5	0.12	2.2e-09	-4.7	-5.5	2.9e-08	0.91	0.02	0.98	FALSE
11	GTEx	Nerve Tibial	L3MBTL3	0.30	0.23	lasso	4	0.22	2.3e-15	-4.7	-5.1	2.6e-07	0.87	0.69	0.30	FALSE
12	GTEx	Pancreas	L3MBTL3	0.32	0.17	lasso	4	0.23	4.4e-10	-4.7	-5.3	1.4e-07	0.88	0.09	0.91	FALSE
13	GTEx	Skin Sun Exposed Lower leg	L3MBTL3	0.25	0.25	lasso	9	0.24	1.4e-19	-4.7	-5.2	2.3e-07	0.86	0.58	0.41	FALSE
14	GTEx	Small Intestine Terminal Ileum	L3MBTL3	0.37	0.20	lasso	4	0.17	1.3e-04	-4.7	-5.1	3.1e-07	0.86	0.02	0.87	FALSE
15	GTEx	Spleen	L3MBTL3	0.64	0.34	enet	14	0.48	6.4e-14	-4.7	-5.6	1.7e-08	0.88	0.04	0.96	FALSE
16	GTEx	Stomach	RP11-73O6.3	0.21	0.12	lasso	6	0.06	5.9e-04	-5.9	-6.5	9.7e-11	0.89	0.01	0.96	TRUE
17	GTEx	Thyroid	L3MBTL3	0.40	0.39	enet	9	0.43	2.8e-35	-4.7	-5.5	2.9e-08	0.90	0.69	0.30	FALSE
18	GTEx	Thyroid	RP11-73O6.3	0.18	0.15	lasso	3	0.20	2.3e-15	-5.6	-5.6	2.3e-08	0.91	0.02	0.98	FALSE