Best TWAS P=2.45e-20 · Best GWAS P=3.04e-22 conditioned to 0.000425
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | JAZF1 | 0.04 | 0.02 | blup | 224 | 0.03 | 3.8e-06 | 4.7 | 5.8 | 7.9e-09 | 0.49 | 0.55 | 0.29 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | JAZF1 | 0.12 | 0.09 | lasso | 4 | 0.09 | 2.1e-09 | 8.6 | 9.2 | 2.5e-20 | 0.84 | 0.02 | 0.98 | TRUE |