Best TWAS P=1.37e-08 · Best GWAS P=1.59e-08 conditioned to 0.0334
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BTBD8 | 0.06 | 0.00 | bslmm | 441 | 0.02 | 1.3e-03 | -2.0 | 5.5 | 4.5e-08 | -0.51 | 0.04 | 0.16 | TRUE |
2 | GTEx | Artery Tibial | EVI5 | 0.08 | 0.08 | lasso | 10 | 0.12 | 9.5e-10 | -3.9 | -5.4 | 8.2e-08 | 0.20 | 0.09 | 0.91 | FALSE |
3 | The Cancer Genome Atlas | Glioblastoma Multiforme | EVI5 | 0.14 | 0.04 | blup | 93 | 0.06 | 8.9e-03 | -5.4 | -5.4 | 7.3e-08 | 0.21 | 0.04 | 0.64 | FALSE |
4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | EVI5 | 0.04 | 0.02 | blup | 96 | 0.04 | 1.4e-03 | -5.5 | -5.7 | 1.4e-08 | 0.19 | 0.04 | 0.62 | TRUE |