[Hub]/) : Traits : Impedance of leg (left) : ← →

chr9:110,932,294-112,472,083

Best TWAS P=5.6e-12 · Best GWAS P=4.95e-09 conditioned to 0.0382

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CTNNAL1	0.10	0.00	lasso	7	0.06	1.3e-07	-3.7	-5.8	6.6e-09	0.48	0.12	0.87	FALSE
2	GTEx	Adipose Subcutaneous	IKBKAP	0.08	0.08	lasso	4	0.07	4.6e-06	5.8	5.5	3.8e-08	-0.13	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	CTNNAL1	0.22	0.20	enet	14	0.22	7.1e-18	4.7	-5.3	1.1e-07	0.29	0.72	0.27	FALSE
4	GTEx	Artery Aorta	IKBKAP	0.15	0.14	lasso	4	0.15	1.9e-08	5.8	5.9	3.8e-09	-0.15	0.02	0.98	FALSE
5	GTEx	Artery Aorta	CTNNAL1	0.17	0.06	lasso	6	0.05	9.5e-04	-3.7	-5.8	6.9e-09	0.51	0.09	0.80	FALSE
6	GTEx	Breast Mammary Tissue (Male)	CTNNAL1	0.20	-0.01	lasso	4	-0.01	5.9e-01	4.2	-5.3	1.2e-07	0.08	0.06	0.23	FALSE
7	GTEx	Cells Transformed fibroblasts	CTNNAL1	0.22	0.08	enet	21	0.19	2.1e-14	4.9	-5.1	2.7e-07	0.30	0.23	0.77	FALSE
8	GTEx	Esophagus Muscularis	IKBKAP	0.16	0.14	lasso	7	0.11	4.8e-07	5.8	6.0	2.1e-09	-0.12	0.02	0.98	FALSE
9	GTEx	Lung	IKBKAP	0.11	0.11	lasso	5	0.10	1.9e-08	5.8	5.9	3.4e-09	-0.14	0.01	0.99	FALSE
10	GTEx	Muscle Skeletal	CTNNAL1	0.42	0.14	lasso	7	0.27	7.6e-27	-3.7	-6.0	1.9e-09	0.45	0.98	0.02	FALSE
11	GTEx	Nerve Tibial	IKBKAP	0.13	0.16	lasso	7	0.14	3.7e-10	5.8	6.0	1.9e-09	-0.11	0.01	0.99	FALSE
12	GTEx	Pancreas	CTNNAL1	0.41	0.18	lasso	9	0.19	2.6e-08	4.9	-6.4	2.1e-10	0.29	0.37	0.61	FALSE
13	GTEx	Pituitary	IKBKAP	0.29	0.24	lasso	9	0.23	2.0e-06	5.8	5.6	2.1e-08	-0.07	0.02	0.91	FALSE
14	GTEx	Skin Sun Exposed Lower leg	CTNNAL1	0.12	0.09	lasso	5	0.09	1.2e-07	4.9	-5.3	1.3e-07	0.14	0.09	0.91	FALSE
15	GTEx	Spleen	CTNNAL1	0.66	0.06	enet	84	0.18	2.8e-05	4.9	-5.3	1.2e-07	0.39	0.03	0.85	FALSE
16	GTEx	Whole Blood	CTNNAL1	0.14	0.07	lasso	6	0.07	9.4e-07	-3.7	-5.2	1.6e-07	0.60	0.04	0.94	FALSE
17	METSIM	Adipose	IKBKAP	0.08	0.01	blup	648	0.03	1.7e-05	5.8	5.6	2.1e-08	-0.18	0.04	0.94	FALSE
18	YFS	Blood	CTNNAL1	0.15	0.07	enet	29	0.08	2.8e-26	-3.7	-5.3	9.4e-08	0.76	0.99	0.00	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CTNNAL1	0.29	0.06	enet	12	0.12	8.8e-14	4.9	-5.5	4.8e-08	0.46	0.25	0.75	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CTNNAL1	0.21	0.02	lasso	3	0.06	2.1e-03	4.9	-6.1	1.0e-09	0.44	0.02	0.57	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	CTNNAL1	0.09	0.00	blup	83	0.04	1.0e-04	-3.7	-6.9	5.6e-12	0.61	0.02	0.57	TRUE