TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of leg (left)
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chr12:103,468,478-104,930,610
Best TWAS P=1.76e-08 · Best GWAS P=5.28e-09 conditioned to 1
103.4M
103.6M
103.8M
104M
104.2M
104.4M
104.6M
104.8M
105M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
STAB2
0.17
0.12
lasso
5
0.11
2.0e-12
-5.76
-5.6
1.8e-08
0.99
0.01
0.99
TRUE
2
The Cancer Genome Atlas
Colon Adenocarcinoma
STAB2
0.13
0.10
lasso
5
0.08
1.5e-05
-5.84
-5.6
1.9e-08
0.99
0.01
0.99
FALSE
1
GTEx
Adipose Visceral Omentum
NT5DC3
0.21
0.00
enet
30
0.09
3.1e-05
-0.22
5.1
2.9e-07
-0.38
0.07
0.66
FALSE