Best TWAS P=2.55e-11 · Best GWAS P=6.77e-13 conditioned to 0.00477
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | UGGT2 | 0.23 | 0.09 | lasso | 8 | 0.09 | 3.6e-04 | 4.3 | 5.1 | 2.7e-07 | -0.61 | 0.41 | 0.15 | FALSE |
| 2 | GTEx | Colon Transverse | DNAJC3 | 0.10 | 0.06 | lasso | 7 | 0.05 | 1.8e-03 | -5.3 | 6.7 | 2.5e-11 | -0.86 | 0.02 | 0.93 | TRUE |
| 3 | METSIM | Adipose | UGGT2 | 0.12 | 0.14 | lasso | 15 | 0.13 | 3.9e-19 | 4.9 | 5.3 | 1.4e-07 | -0.69 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HS6ST3 | 0.06 | 0.03 | blup | 307 | 0.03 | 7.4e-05 | 4.2 | -5.3 | 1.0e-07 | 0.72 | 0.05 | 0.85 | FALSE |