Best TWAS P=2.57e-20 · Best GWAS P=2.52e-19 conditioned to 0.115
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | 7 | -7.3 | 2.3e-13 | -0.61 | 0.4 | 0.58 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | 9 | -9.2 | 2.6e-20 | -0.90 | 0.0 | 0.78 | TRUE |