[Hub]/) : Traits : Impedance of leg (left) : ← →

chr16:49,403,920-50,831,256

Best TWAS P=1.11e-08 · Best GWAS P=1.5e-07 conditioned to 0.723

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Aorta	HEATR3	0.41	0.41	enet	62	0.42	5.4e-25	5.3	-5.7	1.1e-08	-0.89	0.01	0.99	TRUE
10	GTEx	Brain Cortex	HEATR3	0.51	0.46	lasso	11	0.47	8.5e-15	5.3	-5.6	1.8e-08	-0.98	0.01	0.99	FALSE
22	GTEx	Ovary	RP11-429P3.3	0.27	0.11	enet	15	0.15	1.9e-04	4.7	-5.5	2.8e-08	-0.80	0.02	0.91	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	HEATR3	0.13	0.07	blup	39	0.10	5.1e-04	4.8	-5.5	3.2e-08	-0.93	0.01	0.89	FALSE
11	GTEx	Brain Frontal Cortex BA9	HEATR3	0.30	0.20	lasso	10	0.16	5.6e-05	5.2	-5.5	3.6e-08	-0.98	0.01	0.96	FALSE
7	GTEx	Brain Caudate basal ganglia	HEATR3	0.36	0.14	lasso	12	0.20	2.6e-06	5.2	-5.5	4.0e-08	-0.94	0.01	0.98	FALSE
20	GTEx	Lung	HEATR3	0.34	0.40	enet	19	0.41	6.4e-34	5.3	-5.4	6.1e-08	-0.98	0.01	0.99	FALSE
2	GTEx	Adrenal Gland	HEATR3	0.33	0.30	lasso	9	0.31	1.3e-11	5.3	-5.4	6.7e-08	-0.98	0.01	0.99	FALSE
4	GTEx	Artery Aorta	RP11-429P3.3	0.15	0.15	lasso	4	0.14	5.6e-08	5.3	-5.3	1.1e-07	-0.99	0.01	0.99	FALSE
13	GTEx	Brain Hypothalamus	HEATR3	0.26	0.01	lasso	6	0.01	1.9e-01	5.3	-5.3	1.1e-07	-0.99	0.02	0.80	FALSE
5	GTEx	Artery Coronary	HEATR3	0.30	0.25	lasso	5	0.25	6.0e-09	5.3	-5.3	1.2e-07	-0.99	0.01	0.99	FALSE
8	GTEx	Brain Cerebellum	HEATR3	0.70	0.66	lasso	7	0.69	1.4e-27	5.3	-5.3	1.2e-07	-0.98	0.01	0.99	FALSE
24	GTEx	Spleen	HEATR3	0.43	0.13	lasso	9	0.13	2.7e-04	5.2	-5.3	1.2e-07	-0.96	0.01	0.98	FALSE
29	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	HEATR3	0.14	0.04	blup	39	0.08	3.2e-04	4.9	-5.3	1.2e-07	-0.83	0.01	0.76	FALSE
25	GTEx	Stomach	HEATR3	0.36	0.27	enet	14	0.28	1.6e-13	4.9	-5.3	1.3e-07	-0.97	0.01	0.98	FALSE
26	GTEx	Testis	HEATR3	0.47	0.37	enet	33	0.38	4.5e-18	5.2	-5.3	1.3e-07	-0.94	0.01	0.99	FALSE
18	GTEx	Esophagus Muscularis	HEATR3	0.40	0.38	lasso	8	0.39	6.1e-25	5.2	-5.3	1.4e-07	-0.99	0.01	0.99	FALSE
21	GTEx	Ovary	HEATR3	0.30	0.14	lasso	11	0.16	1.2e-04	5.2	-5.3	1.4e-07	-0.97	0.02	0.92	FALSE
23	GTEx	Pituitary	HEATR3	0.55	0.36	lasso	7	0.48	1.3e-13	5.3	-5.3	1.4e-07	-0.93	0.01	0.98	FALSE
14	GTEx	Brain Putamen basal ganglia	HEATR3	0.27	0.16	lasso	6	0.15	2.3e-04	5.3	-5.2	1.6e-07	-0.96	0.02	0.87	FALSE
6	GTEx	Artery Tibial	HEATR3	0.27	0.31	enet	17	0.32	2.1e-25	5.2	-5.2	1.8e-07	-0.99	0.01	0.99	FALSE
15	GTEx	Cells Transformed fibroblasts	HEATR3	0.22	0.18	lasso	15	0.20	1.4e-14	4.9	-5.2	1.8e-07	-0.93	0.02	0.98	FALSE
19	GTEx	Heart Atrial Appendage	HEATR3	0.30	0.30	lasso	8	0.27	1.1e-12	5.3	-5.2	1.8e-07	-1.00	0.01	0.99	FALSE
17	GTEx	Colon Transverse	HEATR3	0.36	0.36	lasso	7	0.36	9.1e-18	5.2	-5.2	2.0e-07	-1.00	0.01	0.99	FALSE
9	GTEx	Brain Cerebellum	RP11-429P3.3	0.40	0.22	enet	11	0.26	1.9e-08	5.3	-5.2	2.2e-07	-0.90	0.01	0.98	FALSE
1	GTEx	Adipose Subcutaneous	HEATR3	0.17	0.19	lasso	8	0.20	2.3e-16	5.2	-5.1	2.7e-07	-0.99	0.01	0.99	FALSE
12	GTEx	Brain Hippocampus	HEATR3	0.27	0.23	enet	9	0.19	3.9e-05	5.3	-5.1	2.9e-07	-1.00	0.01	0.96	FALSE
16	GTEx	Colon Sigmoid	HEATR3	0.27	0.32	lasso	5	0.28	1.6e-10	5.2	-5.1	2.9e-07	-0.99	0.01	0.99	FALSE
27	GTEx	Testis	RP11-429P3.3	0.21	0.03	lasso	5	0.03	1.6e-02	5.2	-5.1	3.1e-07	-0.99	0.02	0.87	FALSE