[Hub]/) : Traits : Impedance of leg (left) :

chr16:52,772,129-54,846,383

Best TWAS P=4.73e-42 · Best GWAS P=3.03e-154 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FTO 0.11 0.00 bslmm 739 0.02 1.6e-03 1.6 -11.5 1.0e-30 0.38 0.09 0.55 TRUE
2 CommonMind Brain Pre-frontal Cortex RBL2 0.22 0.24 enet 15 0.26 1.8e-31 -4.8 6.1 1.1e-09 0.02 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous RBL2 0.34 0.28 enet 18 0.30 1.0e-24 -4.8 5.9 3.2e-09 0.02 1.00 0.00 FALSE
4 GTEx Artery Tibial RBL2 0.16 0.17 enet 11 0.20 2.1e-15 -4.9 6.0 2.5e-09 0.02 1.00 0.00 FALSE
5 GTEx Brain Cortex RBL2 0.51 0.45 enet 12 0.46 3.5e-14 -4.6 6.4 1.3e-10 0.02 1.00 0.00 TRUE
6 GTEx Colon Sigmoid RBL2 0.38 0.37 lasso 12 0.29 8.4e-11 -4.8 5.5 3.6e-08 0.03 1.00 0.00 FALSE
7 GTEx Esophagus Mucosa RBL2 0.36 0.36 enet 37 0.37 2.9e-26 -4.8 5.8 7.1e-09 0.00 1.00 0.00 TRUE
8 GTEx Lung RBL2 0.29 0.37 enet 16 0.35 9.1e-28 -4.8 5.3 1.2e-07 0.03 1.00 0.00 FALSE
9 GTEx Muscle Skeletal RBL2 0.11 0.00 lasso 5 0.00 2.9e-01 -6.9 9.8 7.6e-23 -0.10 0.28 0.23 TRUE
10 GTEx Nerve Tibial RBL2 0.46 0.52 enet 19 0.53 1.6e-43 -4.8 5.2 1.8e-07 0.04 1.00 0.00 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic RBL2 0.35 0.33 enet 16 0.34 2.6e-19 -4.8 5.4 5.4e-08 0.03 1.00 0.00 FALSE
12 GTEx Skin Sun Exposed Lower leg RBL2 0.35 0.39 enet 25 0.37 2.9e-32 -4.8 5.1 2.7e-07 0.03 1.00 0.00 FALSE
13 GTEx Spleen RBL2 0.59 0.47 enet 51 0.46 3.2e-13 -4.8 5.4 8.1e-08 -0.06 1.00 0.00 TRUE
14 GTEx Testis AKTIP 0.19 0.00 enet 26 0.00 1.9e-01 -4.6 -13.6 4.7e-42 0.51 0.03 0.40 TRUE
15 GTEx Vagina RBL2 0.41 0.37 enet 13 0.34 1.6e-08 -4.5 5.2 2.5e-07 0.03 0.89 0.01 FALSE
16 YFS Blood AKTIP 0.19 0.27 lasso 13 0.30 3.3e-99 -7.2 -6.6 3.7e-11 -0.01 1.00 0.00 TRUE
17 The Cancer Genome Atlas Esophageal Carcinoma RBL2 0.08 0.04 lasso 3 0.03 4.4e-02 -7.2 -5.3 1.1e-07 0.00 0.01 0.81 TRUE
18 The Cancer Genome Atlas Glioblastoma Multiforme FTO 0.27 0.16 enet 13 0.14 6.7e-05 2.0 -8.8 2.0e-18 0.33 0.11 0.32 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma RBL2 0.03 0.06 enet 5 0.05 8.2e-07 -4.6 5.7 1.6e-08 0.04 0.62 0.37 FALSE
20 The Cancer Genome Atlas Pancreatic Adenocarcinoma RBL2 0.11 0.08 blup 44 0.06 1.5e-03 -6.8 7.0 1.9e-12 -0.03 0.01 0.80 FALSE
21 The Cancer Genome Atlas Testicular Germ Cell Tumors AKTIP 0.18 -0.01 enet 10 0.08 6.9e-04 2.2 5.3 1.3e-07 -0.01 0.01 0.29 TRUE