[Hub]/) : Traits : Impedance of leg (left) : ← →

chr16:52,772,129-54,846,383

Best TWAS P=4.73e-42 · Best GWAS P=3.03e-154 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	GTEx	Testis	AKTIP	0.19	0.00	enet	26	0.00	1.9e-01	-4.6	-13.6	4.7e-42	0.51	0.03	0.40	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FTO	0.11	0.00	bslmm	739	0.02	1.6e-03	1.6	-11.5	1.0e-30	0.38	0.09	0.55	TRUE
9	GTEx	Muscle Skeletal	RBL2	0.11	0.00	lasso	5	0.00	2.9e-01	-6.9	9.8	7.6e-23	-0.10	0.28	0.23	TRUE
16	YFS	Blood	AKTIP	0.19	0.27	lasso	13	0.30	3.3e-99	-7.2	-6.6	3.7e-11	-0.01	1.00	0.00	TRUE
5	GTEx	Brain Cortex	RBL2	0.51	0.45	enet	12	0.46	3.5e-14	-4.6	6.4	1.3e-10	0.02	1.00	0.00	TRUE
7	GTEx	Esophagus Mucosa	RBL2	0.36	0.36	enet	37	0.37	2.9e-26	-4.8	5.8	7.1e-09	0.00	1.00	0.00	TRUE
13	GTEx	Spleen	RBL2	0.59	0.47	enet	51	0.46	3.2e-13	-4.8	5.4	8.1e-08	-0.06	1.00	0.00	TRUE
17	The Cancer Genome Atlas	Esophageal Carcinoma	RBL2	0.08	0.04	lasso	3	0.03	4.4e-02	-7.2	-5.3	1.1e-07	0.00	0.01	0.81	TRUE
21	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AKTIP	0.18	-0.01	enet	10	0.08	6.9e-04	2.2	5.3	1.3e-07	-0.01	0.01	0.29	TRUE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	FTO	0.27	0.16	enet	13	0.14	6.7e-05	2.0	-8.8	2.0e-18	0.33	0.11	0.32	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RBL2	0.11	0.08	blup	44	0.06	1.5e-03	-6.8	7.0	1.9e-12	-0.03	0.01	0.80	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RBL2	0.22	0.24	enet	15	0.26	1.8e-31	-4.8	6.1	1.1e-09	0.02	1.00	0.00	FALSE
4	GTEx	Artery Tibial	RBL2	0.16	0.17	enet	11	0.20	2.1e-15	-4.9	6.0	2.5e-09	0.02	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	RBL2	0.34	0.28	enet	18	0.30	1.0e-24	-4.8	5.9	3.2e-09	0.02	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	RBL2	0.03	0.06	enet	5	0.05	8.2e-07	-4.6	5.7	1.6e-08	0.04	0.62	0.37	FALSE
6	GTEx	Colon Sigmoid	RBL2	0.38	0.37	lasso	12	0.29	8.4e-11	-4.8	5.5	3.6e-08	0.03	1.00	0.00	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	RBL2	0.35	0.33	enet	16	0.34	2.6e-19	-4.8	5.4	5.4e-08	0.03	1.00	0.00	FALSE
8	GTEx	Lung	RBL2	0.29	0.37	enet	16	0.35	9.1e-28	-4.8	5.3	1.2e-07	0.03	1.00	0.00	FALSE
10	GTEx	Nerve Tibial	RBL2	0.46	0.52	enet	19	0.53	1.6e-43	-4.8	5.2	1.8e-07	0.04	1.00	0.00	FALSE
15	GTEx	Vagina	RBL2	0.41	0.37	enet	13	0.34	1.6e-08	-4.5	5.2	2.5e-07	0.03	0.89	0.01	FALSE
12	GTEx	Skin Sun Exposed Lower leg	RBL2	0.35	0.39	enet	25	0.37	2.9e-32	-4.8	5.1	2.7e-07	0.03	1.00	0.00	FALSE