TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (left)
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chr19:1,127,720-2,560,423
Best TWAS P=3.96e-10 · Best GWAS P=1.18e-10 conditioned to 0.000172
1.2M
1.4M
1.6M
1.8M
2M
2.2M
2.4M
2.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
REXO1
0.07
0.01
bslmm
391
0.01
1.7e-02
3.4
-6.3
4.0e-10
-0.51
0.1
0.66
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
KLF16
0.12
0.08
bslmm
372
0.08
1.0e-10
6.4
6.0
2.2e-09
0.85
0.0
1.00
FALSE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
ATP8B3
0.04
0.01
blup
49
0.02
2.2e-03
6.4
5.9
3.0e-09
0.84
0.0
0.76
FALSE