Best TWAS P=3.96e-10 · Best GWAS P=1.18e-10 conditioned to 0.000172
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | REXO1 | 0.07 | 0.01 | bslmm | 391 | 0.01 | 1.7e-02 | 3.4 | -6.3 | 4.0e-10 | -0.51 | 0.1 | 0.66 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | KLF16 | 0.12 | 0.08 | bslmm | 372 | 0.08 | 1.0e-10 | 6.4 | 6.0 | 2.2e-09 | 0.85 | 0.0 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ATP8B3 | 0.04 | 0.01 | blup | 49 | 0.02 | 2.2e-03 | 6.4 | 5.9 | 3.0e-09 | 0.84 | 0.0 | 0.76 | FALSE |