Best TWAS P=4.9e-10 · Best GWAS P=2.42e-11 conditioned to 0.00625
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | CCNE1 | 0.31 | 0.19 | lasso | 9 | 0.21 | 6.3e-12 | -6.3 | -5.5 | 4.2e-08 | 0.82 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CCNE1 | 0.27 | 0.22 | lasso | 8 | 0.24 | 2.5e-19 | -6.2 | -5.4 | 5.9e-08 | 0.81 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | CCNE1 | 0.03 | 0.02 | blup | 39 | 0.02 | 4.5e-03 | -6.2 | -5.6 | 2.5e-08 | 0.83 | 0.02 | 0.92 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CCNE1 | 0.03 | 0.03 | enet | 5 | 0.03 | 3.2e-04 | -6.2 | 6.2 | 4.9e-10 | -0.83 | 0.01 | 0.98 | TRUE |