Best TWAS P=7.18e-09 · Best GWAS P=1.31e-07 conditioned to 0.00366
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AC006547.14 | 0.09 | 0.00 | lasso | 4 | 0.00 | 6.9e-01 | -3.5 | 5.3 | 1.4e-07 | 0.44 | 0.03 | 0.27 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | ZDHHC8 | 0.18 | 0.07 | enet | 26 | 0.14 | 8.9e-11 | 4.9 | 5.8 | 7.2e-09 | 0.47 | 0.04 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARVCF | 0.03 | 0.01 | blup | 116 | 0.01 | 1.1e-02 | 4.3 | 5.4 | 5.1e-08 | 0.61 | 0.01 | 0.44 | FALSE |