TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of leg (left)
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chr22:19,420,959-20,330,744
Best TWAS P=7.18e-09 · Best GWAS P=1.31e-07 conditioned to 0.00366
19.4M
19.6M
19.8M
20M
20.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
ZDHHC8
0.18
0.07
enet
26
0.14
8.9e-11
4.9
5.8
7.2e-09
0.47
0.04
0.96
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
ARVCF
0.03
0.01
blup
116
0.01
1.1e-02
4.3
5.4
5.1e-08
0.61
0.01
0.44
FALSE
1
GTEx
Artery Tibial
AC006547.14
0.09
0.00
lasso
4
0.00
6.9e-01
-3.5
5.3
1.4e-07
0.44
0.03
0.27
FALSE