TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (left)
:
←
chr22:45,199,058-46,691,903
Best TWAS P=5.6e-12 · Best GWAS P=1.88e-11 conditioned to 0.00218
45.2M
45.4M
45.6M
45.8M
46M
46.2M
46.4M
46.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
RIBC2
0.03
0.01
blup
59
0.03
1.8e-04
-4.9
-6.9
5.6e-12
-0.63
0.04
0.93
TRUE
4
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
RIBC2
0.11
0.02
blup
58
0.09
2.0e-04
-4.7
-6.8
1.4e-11
-0.70
0.06
0.56
FALSE
1
GTEx
Cells Transformed fibroblasts
FBLN1
0.09
0.04
lasso
9
0.06
2.4e-05
6.7
-6.0
1.8e-09
-0.95
0.00
0.98
FALSE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
SMC1B
0.10
0.04
lasso
5
0.05
1.1e-06
3.1
-5.4
6.5e-08
-0.38
0.81
0.05
FALSE