Best TWAS P=6.83e-11 · Best GWAS P=3.05e-14 conditioned to 4.24e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | ZFP36L2 | 0.06 | 0.00 | lasso | 8 | 0.01 | 3.5e-02 | 5.9 | -5.1 | 3.1e-07 | -0.54 | 0.20 | 0.28 | FALSE |
| 2 | GTEx | Thyroid | AC010883.5 | 0.11 | 0.09 | lasso | 2 | 0.08 | 1.5e-06 | 6.6 | 6.5 | 6.8e-11 | 0.75 | 0.83 | 0.15 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZFP36L2 | 0.03 | 0.01 | blup | 38 | 0.01 | 1.1e-02 | 2.8 | -6.3 | 3.4e-10 | -0.86 | 0.01 | 0.83 | FALSE |