TWAS
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Traits
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Traits
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Impedance of leg (left)
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chr2:32,483,593-34,319,972
Best TWAS P=1.17e-10 · Best GWAS P=7.77e-11 conditioned to 0.151
32.5M
33M
33.5M
34M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
LTBP1
0.48
0.51
enet
58
0.51
2.4e-43
-5.8
6.4
1.2e-10
-0.93
0.04
0.96
TRUE
1
GTEx
Artery Tibial
LTBP1
0.10
0.04
enet
12
0.03
1.5e-03
-4.5
5.3
8.7e-08
-0.84
0.04
0.95
FALSE