TWAS
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Traits
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Impedance of leg (left)
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chr2:127,113,672-128,561,279
Best TWAS P=6.87e-08 · Best GWAS P=2.26e-08 conditioned to 0.117
127.2M
127.4M
127.6M
127.8M
128M
128.2M
128.4M
128.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Heart Left Ventricle
BIN1
0.15
0.14
lasso
5
0.12
9.3e-07
-5.3
5.4
6.9e-08
-0.93
0
1
TRUE
2
GTEx
Pancreas
BIN1
0.34
0.25
lasso
4
0.24
1.5e-10
-5.4
5.4
6.9e-08
-0.93
0
1
FALSE