TWAS hub - BIN1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.0940	0.0410	8.4e-03	0.001	NA	0.028	NA	0.003	2.6e-01	NA	5.3e-03	NA	1.9e-01
2	GTEx	Esophagus Muscularis	0.2280	0.0640	1.8e-04	0.067	NA	0.134	NA	0.139	6.6e-05	NA	1.7e-08	NA	8.2e-09
3	GTEx	Heart Left Ventricle	0.1504	0.0595	3.4e-03	0.142	NA	0.109	NA	0.116	5.2e-08	NA	2.0e-06	NA	9.3e-07
4	GTEx	Lung	0.1629	0.0530	1.6e-03	0.014	NA	0.061	NA	0.029	2.7e-02	NA	2.0e-05	NA	2.4e-03
5	GTEx	Pancreas	0.3360	0.0920	1.6e-03	0.254	NA	0.190	NA	0.241	3.9e-11	NA	1.9e-08	NA	1.5e-10
6	NTR	Blood	0.0478	0.0144	4.0e-05	0.037	0.020	0.034	0.038	0.033	4.2e-12	4.5e-07	2.7e-11	3.2e-12	6.1e-11
7	YFS	Blood	0.6331	0.0357	0.0e+00	0.462	0.417	0.475	0.469	0.475	2.2e-172	2.6e-150	1.0e-178	1.1e-175	9.6e-179
8	TCGA	Breast Invasive Carcinoma	0.0409	0.0146	1.4e-05	0.017	0.030	0.026	NA	0.028	1.8e-04	6.6e-07	3.3e-06	NA	1.5e-06
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0464	0.0218	6.1e-03	0.038	0.008	0.008	NA	0.016	3.8e-05	4.0e-02	3.5e-02	NA	5.3e-03
10	TCGA	Lung Squamous Cell Carcinoma	0.0375	0.0188	7.3e-03	0.024	0.019	0.019	NA	0.014	8.2e-04	2.8e-03	3.0e-03	NA	7.8e-03
11	TCGA	Thyroid Carcinoma	0.1590	0.0410	5.2e-10	0.089	0.117	0.109	NA	0.090	4.9e-09	2.1e-11	1.0e-10	NA	4.9e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Alzheimer’s Disease (including proxy)	17.7	25.7	81.7	-1.9	-6.8	-5.1	0.5	-5.1	8.4	9.0	4.3	-2.4	1.5	-1.6
Alzheimer’s Disease (in mother)	8.9	10.5	36.6	-0.5	-4.0	-1.9	1.7	-2.1	5.5	6.0	3.8	-0.1	2.4	1.3
Illnesses of mother	4.3	5.3	9.7	-1.8	-0.2	-1.7	-2.5	-1.7	-2.9	-2.8	-3.1	-0.8	-2.9	-2.8
Illness, injury, bereavement, stress in last 2 years	3.8	4.7	13.2	-0.1	0.8	2.5	1.6	2.4	2.0	1.8	2.1	2.5	3.6	2.3
Bipolar Disorder (2011)	3.6	3.5	7.2	0.5	-0.1	-2.4	-2.1	-2.4	-0.3	-0.9	-1.5	-2.7	-2.4	-2.6
Bilateral oophorectomy (both ovaries removed)	3.2	3.7	8.3	-2.9	0.3	-2.3	-1.6	-2.1	-0.6	-1.4	-2.3	-1.6	-2.6	-2.0
Multivitamins +/- minerals	2.9	3.7	7.6	0.1	0.1	2.6	1.6	2.8	1.5	0.8	2.6	2.1	2.5	2.0
Heart attack/myocardial infarction (self-reported)	2.9	3.7	8.8	2.1	2.8	3.0	1.2	2.7	-1.8	-1.1	0.3	1.9	0.9	1.4
Heart attack	2.8	3.6	8.0	2.3	2.6	2.8	1.3	2.6	-1.7	-1.1	0.3	2.0	0.8	1.5
Myopia	2.7	3.9	9.9	-0.8	0.6	-1.6	-1.4	-1.4	-3.1	-2.4	-2.3	-2.1	-2.2	-2.4
Impedance of leg (left)	2.6	12.4	29.1	0.6	0.2	5.4	2.2	5.4	0.7	1.9	3.7	3.8	4.6	4.5
Trunk predicted mass	2.6	14.9	32.7	-1.8	-0.7	-5.5	-3.2	-5.7	0.5	-1.2	-3.8	-4.1	-5.0	-5.3
Impedance of whole body	2.6	13.0	32.5	0.9	0.4	5.7	2.2	5.7	-0.3	1.0	3.5	4.6	4.4	4.4
Trunk fat-free mass	2.5	14.6	32.3	-1.7	-0.6	-5.4	-3.2	-5.7	0.5	-1.1	-3.8	-4.1	-5.0	-5.2
Coronary Artery Disease (CAD)	2.4	2.8	11.7	2.2	3.4	2.2	0.7	2.0	0.2	0.5	0.4	0.9	1.4	1.5
Number of treatments/medications taken	2.4	4.4	9.0	0.9	2.2	1.9	2.1	1.9	2.1	2.8	1.8	0.7	3.0	2.5
Number of full sisters	2.4	2.9	8.6	-1.0	-1.6	-2.9	-0.9	-2.6	0.3	-0.5	-1.2	-1.4	-2.5	-1.4
Whole body water mass	2.4	13.6	30.4	-1.9	-0.7	-5.3	-2.9	-5.5	0.5	-1.2	-3.8	-3.7	-4.8	-5.0
Medication: Paracetamol	2.4	3.7	8.9	0.4	1.8	1.7	1.8	1.8	2.5	3.0	0.7	0.8	2.6	2.0
Whole body fat-free mass	2.3	12.9	29.6	-1.8	-0.8	-5.2	-2.8	-5.4	0.6	-1.0	-3.6	-3.6	-4.6	-4.9
Supplements: Fish oil (including cod liver oil)	2.3	3.1	7.4	0.6	1.4	2.5	1.7	2.7	0.0	0.4	1.0	2.2	2.4	1.7
Alzheimer’s Disease (in father)	2.2	2.4	5.4	-1.4	-2.0	-1.6	-0.6	-1.5	2.1	2.3	0.4	-1.3	0.4	-1.7
Diabetes (father)	2.2	2.7	6.4	-1.3	-0.9	-2.0	-1.8	-2.2	-1.5	-0.9	-1.7	-1.7	-2.5	-0.1
Current tobacco smoking	2.2	3.7	8.9	1.1	0.8	3.0	2.1	2.9	0.5	0.9	1.2	1.8	1.8	2.8
Stomach or abdominal pain in last month	2.2	2.8	8.0	0.9	0.5	-2.1	-1.0	-1.7	0.4	-0.3	-1.9	-2.7	-1.5	-2.8
Suffer from ‘nerves’	2.2	3.4	6.6	2.0	0.2	2.0	0.2	1.9	2.2	2.6	1.7	1.3	1.8	2.4
Arm fat-free mass (left)	2.2	11.0	25.0	-2.0	-0.7	-4.9	-2.3	-5.0	0.8	-0.6	-3.4	-3.5	-4.1	-4.5
Fractured/broken bones in last 5 years	2.2	2.9	5.9	-0.9	-1.9	-2.3	-2.2	-2.4	-0.7	-0.6	-1.7	-1.5	-1.9	-1.1
Depression (self-reported)	2.1	2.5	8.9	3.0	1.6	1.5	-0.0	1.4	1.3	0.8	1.8	-0.2	1.9	1.6
Impedance of arm (left)	2.1	9.6	24.7	1.1	1.0	5.0	1.6	4.8	-0.9	0.0	2.9	3.9	3.7	3.8
Length of working week for main job	2.1	2.3	7.1	-1.2	0.4	-0.5	-0.9	-0.4	-2.3	-2.7	-2.5	0.9	-1.1	-1.1
Arm predicted mass (left)	2.1	10.8	25.1	-2.0	-0.8	-4.9	-2.3	-5.0	0.9	-0.3	-3.4	-3.5	-4.1	-4.2
Crohns Disease (2017)	2.0	4.4	15.2	0.0	-0.4	1.2	1.3	1.2	3.5	3.9	1.8	-0.0	3.5	1.0
Severe depression (siblings)	2.0	2.2	5.2	0.3	0.7	-1.5	-1.3	-1.3	-1.0	-1.7	-2.3	-1.5	-1.4	-2.1
Arm fat-free mass (right)	2.0	10.3	22.9	-2.0	-1.4	-4.8	-2.3	-4.8	1.2	-0.4	-3.2	-3.1	-4.1	-4.3
Had major operations	2.0	2.4	5.7	0.9	-0.3	0.9	0.4	1.0	2.0	2.4	1.8	1.5	2.0	2.0
Basal metabolic rate	2.0	11.3	26.5	-1.8	-0.7	-5.0	-2.6	-5.2	0.7	-0.8	-3.5	-3.4	-4.2	-4.5
Age at First Birth	1.9	2.8	9.5	3.1	1.6	1.6	1.6	1.4	0.8	1.1	1.6	0.1	1.5	2.3
Systolic Blood Pressure	1.9	9.6	17.7	0.3	-1.0	2.1	2.5	2.5	3.8	3.9	4.2	3.7	4.2	3.0
Systolic blood pressure, automated reading	1.9	5.5	15.2	0.1	-0.2	1.6	1.4	1.6	2.7	3.9	2.9	1.7	3.7	2.4
Hayfever, allergic rhinitis or eczema	1.9	4.0	9.2	2.1	0.8	1.9	0.9	1.4	2.0	3.0	2.8	-0.2	2.5	2.3
Leg predicted mass (left)	1.9	10.1	23.4	-1.8	-0.7	-4.7	-2.4	-4.8	0.5	-1.1	-3.4	-2.9	-4.1	-4.2
Financial difficulties in last 2 years	1.9	2.5	6.0	-0.2	-0.5	-2.4	-1.7	-2.4	0.3	-0.7	-1.6	-1.0	-2.1	-2.1
Medication: Paracetamol	1.9	3.2	6.7	0.2	1.1	1.6	2.0	1.8	2.3	2.6	1.4	0.5	2.4	2.1
Qualifications: College or University degree	1.9	6.0	12.6	0.1	-0.2	-2.6	-2.2	-2.6	-2.3	-3.0	-3.0	-1.7	-3.5	-2.9
Angina (self-reported)	1.9	2.5	6.4	-1.0	-0.1	1.9	2.2	1.9	0.4	0.2	2.1	2.5	1.2	1.4
Arm predicted mass (right)	1.9	9.6	22.1	-1.9	-1.1	-4.7	-2.2	-4.7	1.1	-0.4	-3.1	-3.0	-3.8	-4.2
Smoking Status	1.8	4.3	10.6	0.1	-0.6	3.0	1.8	3.0	1.6	0.9	1.1	3.3	1.8	2.7
Impedance of leg (right)	1.8	8.6	22.8	0.9	0.4	4.7	1.4	4.8	0.3	1.4	2.9	2.8	3.9	3.6
Leg fat-free mass (left)	1.8	9.8	22.3	-1.7	-0.6	-4.6	-2.4	-4.7	0.4	-1.1	-3.4	-2.9	-4.0	-4.2
Impedance of arm (right)	1.8	8.4	23.2	1.1	1.6	4.8	1.2	4.6	-1.6	-0.3	2.6	3.2	3.3	3.4
Medication: Ventolin 100micrograms inhaler	1.8	2.4	5.6	0.6	0.0	1.9	0.9	1.7	0.2	1.0	1.8	2.1	2.4	1.9
Illnesses of father: Heart disease	1.8	2.5	4.7	2.1	2.2	1.9	1.3	1.6	0.8	0.7	1.2	1.4	2.1	1.4
Hearing aid user	1.8	2.0	5.1	1.4	1.9	2.2	-0.1	2.0	-0.1	0.5	0.4	0.1	2.0	1.9
Alcohol drinker status: Previous	1.8	2.1	5.1	-2.1	0.0	-2.0	-0.7	-2.0	0.1	-0.2	-0.9	-2.2	-1.9	-0.3
Waist Hip Ratio (WHR)	1.7	7.5	16.3	1.7	0.4	4.0	1.8	4.0	1.0	1.2	2.2	3.9	3.4	3.2
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.8	8.9	-0.1	0.6	-1.8	-1.1	-1.8	0.7	-0.0	-3.0	-2.0	-1.9	-2.5
Lung cancer (father)	1.7	2.0	5.1	-1.4	0.0	-1.7	0.0	-1.4	-1.0	-1.2	-2.3	-1.3	-2.1	-1.2
High blood pressure (siblings)	1.7	2.4	11.4	-0.4	-0.7	-0.2	1.0	0.3	3.4	3.1	1.1	1.1	0.7	1.2
Osteoarthritis (self-reported)	1.7	2.2	7.3	2.4	0.2	0.2	0.5	0.1	1.9	2.1	1.1	1.4	2.7	0.5
Cholesterol lowering medication	1.7	2.5	6.9	-1.7	-0.1	1.4	2.3	1.6	-0.9	-0.5	1.2	2.6	1.2	1.9
Reaction Time	1.6	3.0	8.5	1.1	1.6	1.8	1.7	2.0	0.6	1.5	1.0	1.5	2.1	2.9
Angina	1.6	2.1	5.6	-1.0	-0.4	1.7	2.0	1.7	0.4	0.1	2.0	2.4	1.1	1.3
Vitamin and mineral supplements	1.6	2.2	5.5	0.5	-0.6	-2.1	-1.4	-2.3	-0.6	-0.5	-1.9	-1.4	-1.8	-1.5
Diabetes (mother)	1.6	2.0	4.3	0.7	0.2	1.8	1.6	1.7	0.2	0.7	1.0	1.9	2.1	1.9
Relative age voice broke	1.6	2.5	10.5	0.9	0.2	-1.5	-3.2	-1.8	-0.7	-1.0	-1.6	-2.0	-1.2	-1.1
Hair/balding pattern: Pattern 2	1.6	2.1	5.3	-0.8	0.5	-1.9	-0.1	-1.5	-0.9	-1.7	-1.8	-1.5	-1.3	-2.3
Alcohol intake versus 10 years previously	1.6	2.4	6.4	-1.4	-1.6	-2.5	-1.4	-2.3	-0.3	-0.3	-1.0	-1.0	-1.1	-2.1
Medication for pain relief, constipation, heartburn	1.6	2.8	6.8	-0.0	-1.8	-1.5	-2.3	-1.6	-1.6	-1.8	-1.0	-1.0	-1.6	-2.6
Medication: Ibuprofen	1.6	1.9	4.4	1.3	0.9	0.9	2.1	0.9	1.5	1.9	0.8	1.0	1.0	1.8
Smoking status: Current	1.6	2.5	6.7	0.4	0.7	2.6	1.9	2.5	0.1	0.5	0.9	1.3	1.4	2.3
Intelligence (Savage-Jansen 2018)	1.5	4.7	10.5	-1.1	-0.3	-3.2	-1.6	-3.2	-0.7	-1.1	-2.1	-3.0	-2.8	-2.1
Neuroticism (2016)	1.5	2.2	5.4	0.5	2.3	-1.4	-0.4	-1.0	-1.3	-1.1	-2.3	-1.7	-1.2	-1.7
Qualifications: A levels/AS levels or equivalent	1.5	3.4	6.2	-0.5	-0.2	-2.1	-2.2	-2.1	-2.0	-2.0	-1.6	-1.5	-2.5	-2.1
Exposure to tobacco smoke at home	1.5	1.6	5.7	-0.7	-0.7	-1.4	-1.8	-1.4	-0.1	-0.8	-0.6	-0.9	-2.4	-1.5
Leg fat-free mass (right)	1.5	8.2	20.4	-1.7	-0.6	-4.3	-1.9	-4.5	0.6	-1.0	-3.0	-2.4	-3.8	-3.8
Leg predicted mass (right)	1.5	8.0	19.8	-1.8	-0.6	-4.3	-1.9	-4.5	0.6	-0.9	-2.9	-2.4	-3.8	-3.7
Number of self-reported non-cancer illnesses	1.5	2.6	6.9	1.3	1.0	0.7	2.4	0.9	1.6	2.6	1.1	0.4	2.6	1.2
Hearing difficulty/problems: Yes	1.4	2.2	3.3	0.6	-0.4	1.7	1.6	1.7	1.7	1.8	1.7	0.8	1.5	1.8
Supplements: Zinc	1.4	1.5	3.6	0.6	-0.2	1.5	1.6	1.7	1.1	1.2	1.9	0.1	0.7	1.3
Fed-up feelings	1.4	2.5	7.6	0.1	0.4	-1.7	-1.1	-1.7	-0.2	-1.1	-2.8	-1.5	-2.5	-1.6
Medication: Levothyroxine sodium	1.4	2.3	6.1	0.4	0.5	2.3	1.6	2.5	0.3	1.0	1.6	1.1	2.2	1.3
Illnesses of siblings	1.4	1.9	6.9	1.0	2.2	1.1	-0.0	0.8	-2.4	-2.6	-0.2	-0.8	-0.4	0.0
Shortness of breath walking on level ground	1.4	1.6	4.2	-1.4	-0.1	-1.3	-2.0	-1.4	-0.8	-0.8	-1.6	-0.8	-1.6	-1.2
Family relationship satisfaction	1.4	1.8	5.1	2.1	0.7	0.6	0.5	0.4	2.2	2.2	1.2	-0.3	1.2	1.0
Commuting to job workplace: Car/motor vehicle	1.4	1.7	6.0	2.4	0.6	0.0	-0.1	-0.5	0.1	1.8	2.0	-0.5	1.5	1.4
Worry (Nagel 2018)	1.3	2.7	12.3	3.5	1.5	1.8	0.3	2.1	0.9	1.1	0.9	1.4	1.2	1.2
Prostate Cancer	1.3	1.8	4.8	-0.8	-0.4	-2.1	-1.0	-2.2	1.4	0.9	-0.2	-2.2	-1.2	-0.4
Glaucoma (self-reported)	1.3	1.6	8.2	-1.7	-2.9	-0.0	-0.3	-0.0	1.6	1.1	0.5	1.3	0.3	-0.5
Medication: Amlodipine	1.3	1.8	3.7	-1.5	0.2	-1.9	-1.7	-1.7	1.1	-0.7	-1.6	-1.3	-1.3	-0.9
Mean time to correctly identify matches	1.3	2.4	6.4	1.6	1.9	1.4	1.3	1.6	0.2	1.0	1.0	1.4	2.1	2.5
Alcohol intake frequency.	1.3	2.9	7.3	-2.5	-1.8	-2.7	-0.6	-2.5	0.9	-0.1	-1.1	-1.5	-1.2	-1.7
Commuting to job workplace: Walk	1.3	1.4	3.6	-0.8	-0.8	-1.6	-1.9	-1.5	0.4	-0.2	-0.1	-1.1	-1.1	-1.6
Medication for cholesterol	1.3	2.0	5.9	1.6	0.7	-0.9	-1.0	-0.9	-0.8	-1.6	-1.8	-1.1	-2.4	-1.5
Cardiovascular Disease	1.2	4.1	9.8	-0.4	-0.8	1.6	1.5	1.9	2.7	2.0	2.3	3.1	2.3	2.0
Nervous feelings	1.2	2.3	4.8	2.2	0.0	1.9	-0.3	1.9	1.8	1.4	1.4	1.8	1.6	0.9
Weight	1.2	6.1	14.8	-1.4	-0.2	-3.7	-2.2	-3.8	0.7	-0.1	-2.9	-2.5	-2.6	-3.1
Exposure to tobacco smoke outside home	1.2	1.7	6.4	-0.9	0.6	-0.4	-1.1	-0.3	-1.5	-2.5	-1.0	-1.3	-1.9	-0.8
Neck or shoulder pain in last month	1.2	1.6	4.3	0.9	0.9	1.2	0.8	1.3	1.7	1.9	0.7	0.2	2.1	1.2
Back pain experienced in last month	1.2	1.7	8.3	-1.3	-0.1	-0.8	0.2	-0.4	2.9	2.5	-0.6	-0.3	0.9	0.5
Sensitivity / hurt feelings	1.1	1.9	7.2	1.7	-0.0	1.9	0.5	1.6	-0.1	0.9	-0.1	2.7	1.9	0.1
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	3.3	-1.5	-1.3	-1.4	0.8	-1.0	1.8	0.7	-0.1	-1.0	-0.5	-0.4
Taking other prescription medications	1.1	1.7	3.3	1.4	1.2	1.1	1.3	1.1	0.9	1.8	1.1	0.3	1.6	1.8
Hearing difficulty/problems with background noise	1.1	1.8	3.9	1.7	-0.3	1.1	1.3	1.1	1.7	2.0	1.7	0.9	1.2	0.5
Mouth/teeth dental problems	1.1	1.7	4.7	-0.6	-2.2	0.5	0.2	0.2	1.8	1.9	1.5	1.0	1.6	0.6
Tense / ‘highly strung’	1.1	1.8	6.0	2.5	1.5	1.1	0.6	1.3	1.3	1.2	-0.5	0.8	1.1	1.6
Number of children fathered	1.1	1.2	3.2	-1.2	-1.6	-1.5	0.9	-1.2	-0.1	-0.2	-0.3	-0.1	-1.1	-1.8
Health satisfaction	1.1	1.4	5.7	1.5	2.4	-0.3	-0.4	-0.7	1.4	1.3	0.7	-1.0	1.3	-0.4
Medication: Seretide 50 evohaler	1.1	1.3	3.0	1.2	0.7	1.5	0.7	1.4	-0.5	0.3	1.2	0.3	1.5	1.7
Average weekly red wine intake	1.1	1.6	3.4	-1.7	-0.5	-0.7	-0.6	-0.9	-1.7	-1.9	-1.3	0.7	-1.4	-1.3
Handedness (chirality/laterality): Left-handed	1.1	1.4	4.2	-1.1	1.3	0.5	-1.1	0.5	-1.5	-2.0	-1.7	-0.2	-0.2	-1.0
Supplements: Calcium	1.1	1.2	3.4	-0.6	-1.8	0.5	1.0	0.4	1.2	1.6	1.4	1.2	0.8	-0.1
Schizophrenia vs Biploar Disorder	1.0	1.3	2.8	-1.4	0.2	1.7	1.1	1.6	-1.2	-0.4	0.8	1.0	0.9	1.4
Verbal and Numeric Reasoning (VNR)	1.0	2.3	4.8	-1.1	-0.3	-2.1	-1.5	-2.2	-0.5	-1.0	-1.8	-2.1	-1.6	-1.2
Allergy or Eczema	1.0	2.5	5.6	2.2	1.2	1.4	0.6	1.0	1.0	2.4	1.5	-1.0	1.9	2.2
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	4.1	1.2	-0.1	-0.5	-0.7	-0.6	1.4	2.0	0.8	-0.0	0.8	2.0
Ever had hysterectomy (womb removed)	1.0	1.2	4.2	-1.4	-1.3	-0.7	0.1	-0.3	2.1	0.9	1.6	0.2	-0.8	0.4
Had menopause	1.0	1.2	3.7	0.2	-0.1	0.8	0.9	0.8	1.2	1.5	1.6	0.8	1.9	0.8
Medication: Gliclazide	1.0	1.1	2.9	-0.3	0.1	-1.7	-1.4	-1.7	0.7	-0.3	-0.7	-1.6	-0.5	-0.4
Average weekly beer plus cider intake	1.0	1.5	3.5	1.4	1.0	1.9	0.6	1.7	0.2	0.5	1.1	1.2	1.4	1.4
Pain experienced in last month	1.0	1.7	7.9	-0.8	-0.1	-0.3	-0.4	-0.4	-2.8	-2.3	-0.4	-1.0	-1.8	-0.7
Major Depression (MDD)	0.9	1.1	8.9	3.0	1.7	0.2	-0.2	0.4	0.0	0.0	0.1	0.4	0.3	0.2
Neuroticism	0.9	2.1	6.6	2.6	1.9	1.8	1.6	2.2	-0.1	0.4	-0.5	0.5	1.0	1.0
Medication for hormone replacement therapy	0.9	1.0	2.4	0.4	-0.4	1.5	1.3	1.3	0.2	0.8	1.3	0.7	1.6	0.3
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	2.3	1.3	-1.5	-0.9	1.5	-0.8	1.2	0.6	0.2	0.1	0.8	-0.3
Supplements: Glucosamine	0.9	1.2	6.6	1.4	2.6	0.5	0.7	0.5	-0.7	-1.1	0.4	-0.7	1.0	-0.6
Fluid intelligence score	0.9	1.9	6.7	-0.3	0.4	-1.6	-2.0	-1.8	0.1	0.3	-1.3	-2.6	-0.5	-1.2
Time employed in main current job	0.9	1.0	3.3	0.3	-0.9	-0.2	-0.0	-0.3	-1.8	-1.7	-1.1	1.0	-0.6	-1.1
Number of live births	0.9	1.3	2.8	0.1	0.8	1.2	1.7	1.4	0.6	1.1	1.0	0.1	1.6	1.3
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	3.0	-0.3	0.1	-1.7	-0.2	-1.3	0.1	-0.4	-1.4	-1.4	-1.6	-1.0
Age at first live birth	0.9	1.6	3.6	0.1	0.3	-1.8	-0.5	-1.9	-1.3	-1.3	-1.5	-1.0	-1.4	-1.3
Miserableness	0.9	1.6	5.3	-0.1	-0.2	-1.6	-0.9	-1.3	1.0	-0.3	-2.3	-0.1	-1.1	-2.2
Tinnitus: Yes, now most or all of the time	0.9	1.0	3.6	0.3	1.1	0.7	-1.1	0.8	-1.1	-1.3	-0.3	1.9	0.0	-0.9
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.9	1.7	-0.2	0.7	1.1	0.6	1.0	1.0	1.2	1.0	1.3	1.2
Illnesses of father: High blood pressure	0.9	1.1	3.4	-0.8	-1.8	0.3	0.2	0.1	1.1	1.1	1.8	1.2	0.4	0.9
Vascular/heart problems diagnosed by doctor	0.9	2.5	6.0	0.7	0.5	-0.9	-1.2	-1.0	-2.1	-1.9	-2.1	-2.5	-2.0	-1.3
Fasting Glucose	0.8	1.0	2.8	-0.8	-0.3	0.3	0.6	0.1	1.6	1.7	1.1	1.0	1.2	0.8
Ulcerative Colitis	0.8	1.2	5.9	1.1	-0.3	-0.7	-0.5	-0.9	-1.2	-0.4	-1.2	-1.0	-0.0	-2.4
Lung FEV1/FVC ratio	0.8	3.9	8.5	2.7	0.7	2.4	1.1	2.0	0.7	1.8	2.9	1.5	1.9	2.5
Hand grip strength (left)	0.8	2.0	5.5	-1.3	-1.9	-0.4	2.3	-0.1	2.3	1.8	1.2	-0.4	0.9	0.5
Medication: Metformin	0.8	1.1	2.4	0.1	1.3	-0.1	-0.1	-0.1	1.4	1.6	1.1	-1.5	1.1	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	3.9	0.9	-0.1	0.8	1.9	0.9	1.2	2.0	1.1	1.1	1.9	1.2
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.6	-1.6	-1.5	-0.9	-0.8	-0.9	0.2	0.1	-0.1	-0.9	-0.8	-1.4
Had other major operations	0.8	0.9	5.1	0.4	0.1	0.3	0.6	0.1	1.1	2.2	1.1	0.1	1.3	0.5
Qualifications: None of the above	0.8	1.7	4.5	-0.6	-0.0	1.3	1.4	1.6	-0.1	0.5	1.1	2.0	1.6	2.1
Hip circumference	0.8	3.6	8.0	-0.3	1.1	-2.7	-1.9	-2.8	0.2	-0.0	-2.5	-2.4	-1.4	-2.4
Breastfed as a baby	0.8	1.0	2.8	-0.2	-1.5	-1.0	-0.0	-0.9	1.5	1.7	1.0	0.5	0.7	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.7	-0.2	1.2	-1.0	-1.2	-1.3	1.0	0.3	-0.4	-1.6	-0.8	-1.7
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.9	0.7	0.3	1.5	0.4	1.7	0.1	0.3	1.0	1.0	0.9	1.5
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	4.6	0.4	0.1	1.9	1.1	2.1	-0.0	0.6	1.3	1.4	1.8	1.0
Migraine (self-reported)	0.8	1.0	6.0	1.1	2.5	0.2	1.2	0.6	0.4	0.7	0.1	-0.7	-0.1	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	3.0	1.6	-1.1	0.2	0.4	0.1	1.1	1.0	0.6	0.6	1.7	0.6
Medication: Aspirin	0.8	1.0	2.8	-0.4	1.0	1.0	1.4	1.1	0.1	-0.4	0.6	1.7	0.1	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.7	1.5	0.3	-0.7	-0.7	-0.9	-1.0	-0.6	-1.6	-0.7	0.0	-1.2
Loneliness, isolation	0.8	1.1	4.1	0.2	-0.5	-0.9	-1.0	-0.7	1.3	0.5	-1.6	0.0	-0.7	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	3.3	-0.5	1.8	1.0	0.1	0.8	-1.5	-1.3	0.0	-0.1	0.2	0.4
Qualifications: nursing, teaching	0.8	1.2	4.6	2.1	1.0	-0.8	-0.5	-1.1	-0.1	0.1	0.1	-1.5	0.4	-1.6
Commuting to job workplace: Public transport	0.8	1.0	3.3	0.5	0.7	1.8	0.9	1.8	-0.4	-0.1	0.6	0.8	0.2	1.3
High cholesterol (Self-reported)	0.8	1.5	4.2	-0.5	0.7	1.5	1.5	1.7	-0.3	-0.2	0.8	2.1	1.3	1.2
Diastolic blood pressure, automated reading	0.8	2.6	11.4	-0.6	-0.5	0.5	0.4	0.2	2.1	3.4	1.6	1.7	2.2	1.3
Depressed Affect (Nagel 2018)	0.7	1.5	6.8	1.9	2.6	-0.5	0.4	-0.0	-0.1	-0.5	-1.2	-1.6	-0.7	-0.9
Breast Cancer	0.7	1.6	4.5	-1.4	-0.5	-1.2	-1.1	-1.3	-0.1	-1.3	-1.8	0.2	-2.1	-1.2
LDL Cholesterol	0.7	1.1	3.4	-1.3	-0.0	0.8	0.1	1.1	0.1	0.5	1.0	0.8	1.6	1.9
Lupus	0.7	1.1	2.9	-1.4	-0.9	0.7	0.2	1.4	0.3	-0.0	1.3	1.7	-0.7	1.3
Relative age of first facial hair	0.7	1.4	4.6	1.4	1.6	-0.1	-2.1	-0.4	-1.0	-0.9	-2.0	-0.5	0.4	-0.7
High blood pressure	0.7	2.0	5.9	-0.5	-0.7	0.2	0.7	0.4	2.4	2.0	1.8	2.0	1.6	0.8
Diabetes (self-reported)	0.7	1.1	2.9	-1.2	0.2	-1.4	-1.0	-1.2	-1.0	-0.6	-0.7	-1.7	-1.2	-0.6
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.9	0.9	1.2	-0.8	-1.0	-1.1	-0.3	0.1	-0.1	-1.4	-0.7	-2.0
Chronic bronchitis/emphysema (mother)	0.7	0.9	2.1	1.1	0.8	1.3	0.9	1.0	0.2	0.6	-0.4	0.5	1.0	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.4	-1.6	0.1	-1.3	-0.4	-1.5	0.5	0.1	-0.5	-1.0	-0.7	-0.4
Eye problems/disorders: None of the above	0.7	0.8	2.0	-0.1	0.8	-0.9	-0.4	-0.9	-1.3	-1.0	-0.8	-0.4	-1.4	-0.6
Hypertension (Self-reported)	0.7	1.8	6.0	-0.9	-0.8	0.0	0.6	0.2	2.4	2.0	1.3	1.8	1.7	0.7
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.6	0.8	0.0	-1.6	0.2	-1.6	-1.2	-1.2	-0.3	-0.5	-1.6	-0.7
Guilty feelings	0.7	1.1	4.3	-0.6	-0.6	-1.5	0.6	-1.2	0.2	-0.1	-0.9	-0.9	-2.1	-0.9
Financial situation satisfaction	0.7	0.9	2.1	1.1	0.7	0.5	-0.4	0.2	1.3	1.0	1.1	0.0	1.5	1.1
Eye problems/disorders: Glaucoma	0.7	0.9	3.4	-1.3	-1.8	0.2	0.2	0.1	1.5	1.1	0.5	0.9	-0.0	-0.5
Ever had prostate specific antigen (PSA) test	0.7	0.9	2.2	0.8	-1.4	-0.9	0.0	-0.9	1.5	1.3	-0.2	-0.1	0.4	-1.1
Ever depressed for a whole week	0.7	0.9	3.5	-0.1	-1.0	-0.5	-0.5	-0.7	1.9	1.6	0.1	-0.8	0.4	1.0
Ovarian Cancer	0.6	0.9	2.7	0.2	-0.3	0.7	0.8	0.5	1.6	1.4	1.3	0.6	1.0	0.6
Crohns Disease (2012)	0.6	1.0	4.0	-0.6	0.0	0.3	0.3	0.1	1.7	1.7	0.6	0.3	2.0	0.3
HbA1C	0.6	0.7	2.4	-0.6	1.5	0.9	-0.8	0.9	0.9	-0.2	0.6	0.3	0.5	0.9
Triglycerides	0.6	0.9	3.5	-1.9	-0.6	-1.5	-0.4	-1.4	-0.1	0.7	-1.1	-0.5	0.0	-0.0
Respiratory disease	0.6	1.2	4.2	1.7	1.2	0.9	0.6	0.9	-2.0	-0.4	-0.3	-1.3	-0.2	1.1
Average weekly spirits intake	0.6	0.7	3.7	-0.5	0.2	-1.4	-0.2	-1.2	-0.1	0.3	-0.4	-1.9	-0.7	-0.3
Hand grip strength (right)	0.6	1.7	5.8	-1.4	-2.4	-1.0	2.4	-0.8	1.3	1.4	0.6	0.2	-0.0	-0.0
High blood pressure (mother)	0.6	0.9	2.4	-0.5	-0.1	0.8	0.2	0.8	1.6	1.2	1.3	0.3	0.8	1.5
Body mass index (BMI)	0.6	2.7	8.0	-0.9	-0.1	-2.8	-0.8	-2.7	0.8	0.6	-1.9	-1.9	-1.3	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	4.0	1.3	2.0	0.4	-0.5	0.4	1.0	0.7	-1.2	-0.4	0.4	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	3.1	0.2	-0.5	0.6	1.3	0.8	1.4	1.8	1.2	0.9	1.4	1.2
Falls in the last year	0.6	0.8	4.6	1.2	2.1	0.6	-0.0	0.4	-0.1	-0.7	-0.1	-0.3	0.2	1.2
Happiness	0.6	0.8	2.9	1.7	1.3	0.0	-0.3	-0.0	0.7	0.4	0.2	-1.4	0.8	0.6
Mouth/teeth dental problems: Dentures	0.6	1.0	2.8	-1.2	0.9	0.1	-0.8	0.0	-1.7	-1.5	-1.4	-0.1	-0.9	-0.7
Arm fat mass (right)	0.6	2.5	6.7	-1.2	0.3	-2.6	-0.9	-2.6	0.4	0.1	-1.9	-1.9	-1.6	-1.6
Peak expiratory flow (PEF)	0.6	1.3	3.7	-0.5	-1.7	-0.4	1.9	-0.1	1.2	1.0	1.5	1.2	1.1	0.0
Blood clot in the leg (DVT)	0.6	0.7	1.9	-0.8	-1.0	-0.7	-0.1	-1.1	-0.6	0.1	-1.4	0.3	-1.1	-1.0
Headache pain in last month	0.6	1.0	6.1	-0.8	-0.7	-0.7	0.8	-0.3	2.5	1.6	0.2	-0.0	-0.2	0.5
Gout (self-reported)	0.6	0.8	3.2	0.0	-1.8	0.6	1.5	0.4	0.6	0.7	0.8	1.0	0.7	0.1
Birth weight	0.6	1.4	6.0	-0.9	-0.9	-0.8	-0.2	-1.0	2.0	2.5	0.6	0.0	1.0	0.6
Medication: Blood pressure	0.6	1.1	6.0	0.2	0.1	0.8	1.5	0.9	1.1	-0.0	0.4	2.4	0.4	0.8
Illnesses of siblings: Diabetes	0.6	0.8	1.6	-0.7	-1.1	-1.0	-1.2	-1.3	-0.3	0.9	-0.6	0.1	0.9	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	-0.4	1.4	0.6	-0.3	0.3	0.9	0.8	1.2	-0.3	1.0	1.1
Arm fat mass (left)	0.6	2.5	6.9	-1.5	-0.0	-2.6	-0.9	-2.5	0.7	0.3	-1.7	-1.7	-1.4	-1.7
Mother’s age at death	0.6	0.7	5.2	2.3	0.6	0.7	-0.4	0.8	0.1	0.3	0.3	0.1	0.8	0.7
Irritability	0.6	1.0	2.5	0.5	0.8	1.3	1.5	1.6	0.5	-0.5	-0.5	0.8	0.1	1.6
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.8	-1.0	-1.1	-0.9	-0.3	-1.2	-0.7	0.1	-1.4	0.0	-1.0	-1.1
Depression (Nagel 2018)	0.5	0.7	4.0	1.1	2.0	0.4	0.6	0.5	0.2	0.0	-0.8	-1.0	0.0	-0.1
Irritable Bowel Disease (IBD)	0.5	1.2	5.4	0.0	0.1	0.2	0.4	0.1	1.5	2.3	0.1	-0.8	2.0	-0.6
Rheumatoid Arthritis	0.5	0.7	1.9	-1.2	-1.4	-0.5	0.6	-0.2	0.6	0.4	-0.5	0.9	-0.1	-1.3
Schizophrenia (2014)	0.5	1.0	3.5	0.6	-1.9	-1.2	0.2	-1.1	-0.1	-0.1	1.2	-0.1	-1.8	0.3
Hypothyroidism (self reported)	0.5	1.1	3.2	0.0	-0.3	1.6	0.9	1.8	0.2	0.2	0.8	1.1	1.6	0.8
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.5	0.0	0.6	-0.6	-0.2	-0.5	1.2	0.7	-1.6	-1.1	-1.0	-0.6
Pack years adult smoking proportion	0.5	0.8	2.8	1.3	1.1	1.0	-1.7	0.7	-0.1	0.2	-0.8	0.4	0.4	-0.1
Serious illness, injury or assault to yourself	0.5	0.6	1.5	0.0	0.5	-0.8	-0.8	-1.0	-0.5	0.1	-0.7	-1.2	-1.2	-1.0
Allergy	0.5	1.2	2.8	-1.4	-0.6	-1.4	-0.8	-0.9	-0.1	-1.7	-1.2	0.4	-1.2	-1.2
Pulse rate	0.5	0.8	2.6	-1.1	0.4	-0.6	-0.7	-0.7	-1.0	-0.8	-0.9	-1.6	-0.5	-0.5
Asthma	0.5	0.9	5.5	1.5	0.9	0.5	0.2	0.4	-2.4	-0.5	-0.2	-0.8	-0.2	0.4
Standing height	0.5	4.5	10.0	-1.2	-0.1	-2.0	-2.9	-2.6	-0.3	-1.5	-2.2	-1.4	-3.0	-3.2
Loud music exposure frequency	0.5	0.5	1.5	-0.4	0.1	-0.7	-1.2	-0.8	0.5	0.3	-0.8	-0.7	-0.8	-0.9
Worry too long after embarrassment	0.5	0.9	2.6	1.3	-0.7	-1.1	-1.0	-1.1	0.1	0.1	-0.7	-0.3	-1.6	-1.1
Leg fat mass (right)	0.5	1.8	4.2	-1.3	0.0	-2.1	-1.1	-2.0	0.8	0.6	-1.7	-1.5	-0.9	-1.1
Overall health rating	0.5	1.0	6.8	0.2	0.5	0.0	0.3	0.2	2.6	1.6	-0.2	0.3	0.7	0.6
Leg pain on walking	0.5	0.7	2.4	1.1	0.6	0.1	-0.1	-0.1	1.5	1.3	0.1	-0.6	1.1	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.7	0.1	0.2	0.7	0.3	0.8	1.3	1.3	0.5	0.1	0.6	1.3
Asthma (self-reported)	0.5	0.9	4.7	1.7	0.8	0.6	0.4	0.5	-2.2	-0.2	0.2	-0.8	0.1	0.4
Medication: Aspirin	0.5	0.7	2.4	-1.1	0.5	0.8	1.0	0.9	0.2	-0.4	0.7	1.5	-0.0	0.8
Alcohol drinker status: Never	0.5	0.5	1.9	-1.0	-1.4	-0.4	-0.9	-0.5	0.8	-0.2	-0.1	0.9	-0.5	-0.4
Number of operations (self-reported)	0.5	0.8	5.0	-0.5	0.3	0.1	0.1	0.0	1.3	2.2	0.5	-0.1	1.0	-0.1
Unable to work because of sickness or disability	0.5	0.7	1.7	-1.0	1.3	0.9	-0.4	0.7	0.6	0.3	0.2	0.6	1.1	1.1
Pack years of smoking	0.5	0.8	4.0	1.2	1.0	0.7	-2.0	0.4	-0.4	-0.2	-1.0	0.4	0.0	-0.2
Bipolar Disorder or Schizophrenia	0.4	1.0	3.9	0.4	-2.0	-1.3	0.2	-1.3	0.8	0.6	0.8	-0.1	-1.5	-0.4
Neuroticism (Nagel 2018)	0.4	1.0	6.2	2.5	2.0	0.4	0.2	0.7	0.4	0.3	-0.3	-0.0	0.1	0.0
Schizophrenia (2018)	0.4	0.8	3.1	-0.5	-1.8	-1.1	-0.1	-1.2	0.4	0.3	1.0	-0.1	-1.4	-0.4
Ulcerative Colitis (UC)	0.4	0.7	2.1	0.7	0.8	-0.5	-0.4	-0.7	-0.2	0.6	-1.0	-1.4	0.6	-1.4
BMI	0.4	2.4	6.8	0.6	0.6	-2.6	-0.6	-2.4	0.8	0.6	-1.9	-2.1	-1.9	-0.5
Lung FVC	0.4	2.2	5.6	-2.2	-2.3	0.4	2.4	1.0	0.2	0.5	0.8	2.0	1.2	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.7	1.3	1.1	0.4	0.5	0.3	0.8	0.9	-0.8	-0.3	-0.4	0.4
Qualifications: CSEs or equivalent	0.4	0.6	1.4	-1.2	-0.9	-0.1	1.0	0.0	0.7	1.0	0.3	1.0	0.7	-0.6
Chronic bronchitis/emphysema (father)	0.4	0.4	2.4	0.2	-0.9	0.3	0.6	0.4	0.2	0.8	-0.4	1.6	0.4	-0.4
Forced vital capacity (FVC)	0.4	1.7	6.6	-1.9	-2.6	-1.1	0.4	-0.9	0.4	-0.7	-0.6	1.8	-0.7	-1.2
Medication: Ramipril	0.4	0.5	2.7	0.6	1.6	0.8	-0.1	0.7	0.2	-0.1	0.4	0.6	1.0	0.1
Medication: Simvastatin	0.4	0.5	2.4	0.1	0.6	0.5	0.9	0.4	-0.0	-0.1	0.4	1.5	0.1	1.3
Neuroticism score	0.4	0.8	4.7	2.2	0.5	0.8	0.7	1.1	0.2	0.2	-0.7	1.0	-0.2	0.2
Worrier / anxious feelings	0.4	0.7	2.8	1.7	-0.8	0.1	0.3	0.2	1.0	0.9	0.6	1.4	-0.0	-0.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	6.3	-1.3	-2.5	-0.2	1.1	-0.1	0.9	0.1	1.0	2.1	0.0	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	2.4	0.5	0.6	0.3	1.6	0.4	0.7	0.8	0.7	0.2	0.1	1.1
Prospective memory result	0.4	0.5	1.8	0.6	0.3	0.1	-1.3	0.2	-0.8	-1.1	-0.4	-0.2	-0.8	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	4.5	-1.0	-2.0	0.4	1.4	0.5	0.8	0.8	0.7	2.1	0.8	0.3
Forced vital capacity (FVC), Best measure	0.4	1.4	6.0	-1.9	-2.4	-0.9	0.6	-0.6	0.3	-0.2	-0.8	1.3	-0.7	-0.9
Comparative body size at age 10	0.4	1.1	3.2	-0.9	-1.0	-1.8	-0.5	-1.7	-0.1	-0.1	-1.1	-0.3	-1.1	-0.9
Number of full brothers	0.4	0.5	2.2	-0.6	0.3	-0.3	0.2	-0.2	-1.5	-0.6	-0.1	-0.1	0.4	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.6	-0.2	-0.1	-1.2	-0.2	-1.2	0.6	0.6	0.2	-1.3	-0.6	-0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.5	3.7	1.9	0.4	0.4	-0.9	0.5	-0.7	0.4	-0.0	0.2	-0.2	-0.1
Heart disease (mother)	0.4	0.5	2.0	1.4	0.9	0.3	1.3	0.5	0.6	-0.2	-0.1	-0.8	-0.0	0.1
Age at last live birth	0.4	0.6	1.3	-0.9	-0.2	-0.9	0.2	-0.9	-1.0	-1.1	-0.6	-0.5	-0.7	-1.0
Knee pain experienced in last month	0.4	0.6	2.8	1.7	0.4	-0.6	-0.2	-0.6	0.0	0.1	-0.9	-1.3	0.3	0.5
Smoking status: Previous	0.4	0.5	1.3	-1.1	-0.8	-0.8	-0.1	-0.7	0.5	-0.1	-0.7	1.0	-0.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	4.7	-0.9	-0.9	0.8	0.5	0.5	0.4	0.7	1.2	2.2	0.4	0.6
Mood swings	0.4	0.7	4.9	2.2	0.7	0.4	1.0	0.6	0.4	-0.3	-0.0	0.5	-0.4	-0.2
Long-standing illness, disability or infirmity	0.4	0.6	2.8	1.7	1.2	-0.3	-0.2	-0.3	0.4	0.7	-0.7	-0.8	0.2	0.1
Mineral and other dietary supplements	0.4	0.5	1.4	-0.4	-0.8	-1.0	-0.8	-1.2	0.6	0.8	-0.4	-0.4	-0.8	-0.0
Average weekly champagne plus white wine intake	0.4	0.5	2.2	1.5	-0.5	-0.4	-0.8	-0.6	0.2	0.2	-0.3	1.4	-0.1	-0.2
Medication: Blood pressure	0.4	0.8	2.9	-1.1	0.0	-0.5	-0.2	-0.4	1.3	1.2	0.3	0.2	1.7	0.7
Medication: Lisinopril	0.4	0.5	2.4	0.9	-0.3	-0.3	1.5	-0.1	1.0	0.8	0.6	0.0	-0.0	-0.3
Medication: Atorvastatin	0.4	0.5	1.6	-0.7	0.4	1.1	0.2	1.3	-0.6	0.2	0.5	0.3	0.7	0.8
Ever smoked	0.4	0.7	4.1	-0.3	0.2	0.9	0.4	0.9	0.1	-0.1	-0.2	2.0	0.7	1.3
Basal cell carcinoma (self-reported)	0.4	0.5	1.0	0.5	0.9	-0.1	-1.0	-0.1	0.7	0.7	0.2	-0.8	1.0	0.7
Heart disease (siblings)	0.4	0.5	2.3	-0.4	-1.5	-0.7	-0.5	-0.8	0.0	0.2	-0.4	-0.1	-0.5	-0.9
Leg fat mass (left)	0.4	1.4	3.3	-1.5	-0.1	-1.8	-0.8	-1.8	0.8	0.6	-1.6	-1.1	-0.7	-0.9
Bipolar Disorder (2018)	0.3	0.5	2.1	1.4	-0.9	-0.7	0.5	-0.6	0.8	0.5	0.4	-0.0	-0.7	-0.2
Blood Platelet Count	0.3	3.2	10.0	0.5	-1.1	-0.4	2.3	-0.5	2.6	3.2	1.4	-0.7	2.7	0.8
Heel T-Score	0.3	2.5	8.1	-0.7	-1.0	0.4	2.9	0.7	1.5	2.2	2.6	-0.1	1.9	0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.8	-1.7	0.2	-0.5	-1.0	-0.4	-0.3	-0.5	-0.2	-0.8	-0.7	-0.1
Chronotype (morning person)	0.3	0.7	2.1	-0.9	-1.5	-0.3	-1.4	-0.6	-0.8	-0.5	0.6	1.0	-0.1	-0.3
Ever used hormone-replacement therapy (HRT)	0.3	0.3	0.8	-0.9	0.9	0.2	0.9	0.2	0.2	0.3	-0.2	-0.0	0.9	-0.5
Medication: Co-codamol	0.3	0.4	1.1	0.2	-0.6	-0.4	-0.3	-0.3	1.0	0.9	-0.1	-0.1	-0.3	1.1
Medication: Atenolol	0.3	0.3	1.3	-0.8	1.0	-0.1	0.3	0.1	0.7	0.4	-0.2	-0.3	-0.0	1.1
Sitting height	0.3	2.2	6.8	-1.1	-1.0	-1.6	-1.8	-2.2	0.7	-0.5	-0.9	0.2	-1.8	-2.6
Number of incorrect matches in round	0.3	0.5	2.4	0.0	-1.4	0.3	-0.1	0.2	-0.5	0.0	-0.0	1.6	-0.5	0.0
Past tobacco smoking	0.3	0.6	2.0	1.4	0.5	0.8	0.2	0.7	-0.1	0.3	1.1	-0.7	0.8	-0.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.2	0.3	0.5	0.9	0.9	1.1	-0.6	-0.6	-0.2	0.2	-0.5	0.3
Father’s age at death	0.3	0.4	2.1	0.7	-1.4	-0.3	0.3	-0.1	-0.6	-0.5	-0.0	1.0	-0.9	-0.1
Hair/balding pattern: Pattern 3	0.3	0.4	1.2	0.7	0.6	0.8	0.4	0.6	-0.5	0.1	-0.4	0.6	0.4	1.1
Noisy workplace	0.3	0.4	1.6	-1.1	-0.4	-0.4	-0.3	-0.2	-1.2	-0.5	0.7	-0.1	0.1	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.2	-0.2	-1.3	-0.1	0.4	0.1	-0.1	-0.1	-0.2	0.1	-1.5	-0.3
Medication: Cholesterol lowering	0.3	0.5	4.4	0.9	2.1	0.3	0.2	0.4	0.4	0.0	-0.4	-0.3	-0.2	0.0
Emphysema/chronic bronchitis	0.3	0.4	1.8	-1.1	-0.2	-0.1	-0.1	-0.2	0.0	-0.8	-1.3	0.0	-0.5	0.4
Medication: Allopurinol	0.3	0.4	1.4	-0.1	-0.8	0.6	1.2	0.3	0.3	0.4	0.5	1.2	0.5	0.3
Comparative height size at age 10	0.3	1.8	5.0	-1.3	-0.6	-1.2	-1.0	-1.3	-0.4	-0.5	-2.2	-1.9	-1.7	-1.4
Chest pain or discomfort	0.3	0.4	1.1	0.7	0.3	-0.5	-0.7	-0.5	-0.1	-0.2	-0.8	-0.1	-0.9	-1.1
Supplements: Vitamin C	0.3	0.4	1.1	-0.6	1.1	0.5	0.7	0.7	-0.9	-0.6	-0.3	-0.5	-0.3	0.3
Ever had bowel cancer screening	0.3	0.4	2.7	0.4	-0.3	-0.8	-0.1	-0.6	0.1	-0.2	-1.6	-0.4	-0.3	-0.3
Diabetes diagnosed by doctor	0.3	0.5	3.4	-0.7	0.6	-0.8	-0.6	-0.7	0.2	0.3	0.2	-1.8	-0.2	0.2
Breast cancer (self-reported)	0.3	0.4	0.8	0.1	-0.9	-0.6	-0.2	-0.5	0.8	0.7	-0.7	0.9	-0.6	0.1
Medication: Bendroflumethiazide	0.3	0.4	2.0	-1.4	-0.7	-0.3	-0.8	-0.1	0.2	0.3	0.5	0.6	0.8	0.1
Risk taking	0.3	0.4	1.4	0.6	-0.4	-0.9	0.1	-0.7	1.2	0.2	-0.1	-0.4	-0.9	0.4
Age started oral contraceptive pill	0.3	0.4	1.3	-1.1	-1.0	0.0	0.7	0.0	0.2	0.2	0.9	0.5	0.4	-0.8
Body Mass Index (BMI) (2010)	0.2	0.3	1.3	-0.9	0.2	-0.1	0.3	-0.2	0.3	1.1	0.3	-0.8	0.2	0.2
Mean Putamen Volume	0.2	0.2	0.5	-0.2	-0.4	-0.3	0.7	-0.1	-0.7	-0.5	-0.4	0.2	-0.5	-0.2
HDL Cholesterol	0.2	0.3	0.6	0.8	-0.8	0.0	0.4	0.1	0.7	0.2	0.1	0.3	-0.6	-0.7
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.0	-0.3	1.0	-0.1	-0.6	-0.3	-1.0	-0.2	-0.5	0.2	0.2	-0.2
Blood Eosinophil Count	0.2	1.2	3.2	-0.6	0.9	0.1	-1.8	0.1	-1.1	-1.4	-1.6	-1.1	-1.1	-0.5
Blood White Count	0.2	1.8	6.4	-1.6	-0.6	0.4	-0.2	0.2	2.5	1.8	0.5	-0.3	2.5	-1.0
Height	0.2	4.7	9.0	-1.2	2.2	-1.3	-3.0	-1.9	-1.1	-1.8	-2.6	-2.2	-2.5	-3.0
Townsend deprivation index at recruitment	0.2	0.3	1.0	0.2	0.4	0.5	0.0	0.4	-0.6	-0.8	-0.1	1.0	-0.9	0.1
Maternal smoking around birth	0.2	0.3	1.1	0.2	0.6	0.9	0.1	0.9	-0.3	-0.1	-0.2	1.1	0.5	-0.2
Age when periods started (menarche)	0.2	0.4	1.5	0.3	1.2	0.7	-0.2	0.5	0.1	-0.9	-0.6	0.5	-0.7	0.3
Trunk fat mass	0.2	0.9	2.9	-1.2	0.4	-1.2	-0.8	-1.3	0.7	0.3	-1.7	-0.5	-0.4	-0.7
Waist circumference	0.2	0.9	2.7	-0.2	0.6	-1.3	-1.3	-1.4	0.3	0.3	-1.6	-0.4	-0.2	-0.9
Alcohol usually taken with meals	0.2	0.4	1.2	0.3	-1.1	-0.5	-0.3	-0.3	0.8	0.7	1.1	-0.1	0.1	0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.1	0.3	0.0	-0.1	-0.9	-0.2	-0.1	0.1	-0.7	-1.0	0.0	-0.2
Pain all over the body in last month	0.2	0.3	0.7	0.3	-0.2	-0.7	0.2	-0.8	0.2	0.8	-0.2	-0.6	-0.6	0.2
Arm fat percentage (right)	0.2	0.7	1.6	-1.1	0.6	-1.3	-0.3	-1.2	0.5	0.7	-1.0	-1.2	-0.3	-0.4
Medication: Lansoprazole	0.2	0.2	0.9	-0.2	-0.9	-0.2	-0.9	-0.3	0.4	0.6	0.3	0.0	-0.0	0.0
Pulse wave Arterial Stiffness index	0.2	0.3	0.7	-0.9	-0.4	0.4	-0.0	0.2	-0.4	-0.8	-0.1	0.4	0.4	-0.8
Birth weight of first child	0.2	0.4	1.5	-0.2	0.4	0.4	1.2	0.6	-0.6	-0.5	-0.0	1.2	0.2	-0.4
Pulse wave reflection index	0.2	0.3	1.2	-0.8	-1.1	0.0	-0.1	-0.0	-0.3	0.0	0.0	0.7	0.1	-0.8
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.6	-0.2	-1.3	0.1	-0.5	0.0	-0.9	0.1	0.2	-0.6	0.4	-0.3
Leg fat percentage (right)	0.2	0.6	2.5	-0.6	0.2	-0.4	-0.5	-0.3	0.9	1.6	-0.7	-0.7	1.0	0.5
Wheeze or whistling in the chest in last year	0.2	0.4	1.9	1.4	0.6	0.5	0.6	0.6	0.5	0.4	-0.0	-0.3	0.5	-0.8
Pulse wave peak to peak time	0.2	0.3	0.9	0.9	0.5	-0.5	-0.2	-0.4	0.3	0.6	-0.0	-0.5	-0.7	0.5
Medication: Omeprazole	0.2	0.3	0.9	0.3	-0.3	-0.6	-0.3	-0.9	-0.3	0.5	-1.0	0.3	0.1	0.3
Whole body fat mass	0.2	0.9	2.3	-1.4	0.3	-1.4	-0.5	-1.3	0.8	0.3	-1.5	-0.7	-0.5	-0.8
Eye problems/disorders: Cataract	0.2	0.3	0.7	0.7	0.3	0.5	0.3	0.4	0.3	0.7	0.8	-0.5	0.8	0.3
Osteoporosis (self-reported)	0.2	0.3	0.7	-0.4	-0.3	-0.5	-0.7	-0.4	0.5	0.5	-0.5	-0.5	-0.2	0.8
Illnesses of father: None of the above (group 1)	0.2	0.3	1.8	-1.3	-0.4	0.2	0.7	0.4	0.1	-0.1	0.3	-0.4	-0.3	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.6	-0.3	-1.1	-0.0	1.6	0.3	0.8	0.7	0.3	0.5	0.1	0.3
Wears glasses or contact lenses	0.2	0.2	0.5	0.3	0.5	-0.5	0.2	-0.5	0.7	0.6	-0.2	0.5	-0.3	-0.5
Ever taken oral contraceptive pill	0.2	0.2	0.9	-0.5	1.0	-0.0	1.0	-0.1	0.2	0.6	0.1	-0.5	-0.2	-0.2
Leg fat percentage (left)	0.2	0.8	3.2	-0.8	0.1	-0.0	0.1	0.0	1.2	1.8	-0.3	0.1	1.5	1.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.6	0.0	0.2	0.4	0.3	0.1	-0.8	0.4	-0.4	0.6	0.7	0.6
Primary Biliary Cirrhosis	0.1	0.2	0.7	0.6	0.7	-0.4	0.6	-0.3	0.3	-0.2	0.3	0.1	0.3	-0.8
Blood Red Count	0.1	1.3	5.6	-1.8	0.1	-0.6	0.8	-0.5	-0.5	-0.7	-2.4	0.5	-0.9	-1.6
Hair Pigment	0.1	2.5	8.9	3.0	1.3	1.8	1.1	1.8	0.0	0.7	1.1	1.1	2.2	1.0
Trunk fat percentage	0.1	0.5	1.5	-0.6	0.6	0.4	0.3	0.5	0.7	0.7	-0.5	0.8	1.2	1.0
Average weekly fortified wine intake	0.1	0.1	0.4	-0.0	-0.2	0.1	-0.5	0.1	0.0	-0.2	-0.2	-0.2	0.4	0.7
Hair/balding pattern: Pattern 4	0.1	0.3	1.2	0.3	0.0	1.1	-0.6	1.0	-0.4	0.1	0.7	-0.2	0.2	0.5
Body fat percentage	0.1	0.4	1.1	-0.7	0.6	0.2	0.2	0.2	0.7	0.9	-0.6	0.3	1.1	0.9
Pulse rate, automated reading	0.1	0.4	2.2	0.3	0.4	0.4	-1.5	0.1	0.0	-0.0	-0.8	-0.9	0.2	-0.6
Arm fat percentage (left)	0.1	0.6	1.4	-1.2	0.2	-1.2	-0.3	-1.1	0.7	0.7	-0.8	-0.8	-0.1	-0.2
Friendships satisfaction	0.1	0.2	0.8	0.9	0.4	-0.0	0.7	0.2	0.0	0.3	0.3	-0.2	0.5	0.0
Commuting to job workplace: Cycle	0.1	0.1	0.3	-0.4	0.0	-0.5	-0.5	-0.4	0.6	0.3	0.1	-0.3	-0.1	0.0
Tanning	0.0	0.6	2.3	-1.5	-1.1	-0.0	0.6	-0.0	0.6	1.0	-0.0	-0.5	-0.0	1.0

Hub : Genes

BIN1

Models

Trait associations