[Hub]/) : Traits : Impedance of leg (left) :

chr2:171,478,402-173,114,238

Best TWAS P=2.81e-29 · Best GWAS P=6.96e-31 conditioned to 0.000147

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CYBRD1 0.33 0.18 lasso 7 0.27 5.2e-33 -5.0 -8.8 1.1e-18 -0.69 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous CYBRD1 0.35 0.19 lasso 6 0.24 7.3e-20 9.5 -9.8 1.2e-22 -0.77 0.00 1.00 FALSE
3 GTEx Adipose Visceral Omentum CYBRD1 0.33 0.10 lasso 10 0.26 4.6e-14 6.7 -9.4 5.8e-21 -0.71 0.03 0.97 FALSE
4 GTEx Artery Aorta CYBRD1 0.52 0.30 lasso 10 0.41 6.0e-24 -5.0 -8.6 6.2e-18 -0.66 0.96 0.04 FALSE
5 GTEx Artery Coronary CYBRD1 0.29 0.01 enet 44 0.11 2.0e-04 6.7 -7.8 6.6e-15 -0.68 0.04 0.61 FALSE
6 GTEx Artery Tibial CYBRD1 0.37 0.08 lasso 9 0.21 3.0e-16 7.9 -9.7 2.0e-22 -0.75 0.00 1.00 FALSE
7 GTEx Breast Mammary Tissue CYBRD1 0.32 0.21 enet 16 0.27 2.0e-14 9.5 -10.2 2.6e-24 -0.74 0.00 1.00 FALSE
8 GTEx Breast Mammary Tissue (Male) CYBRD1 0.35 0.24 lasso 6 0.20 2.4e-05 9.5 -9.9 2.4e-23 -0.72 0.00 0.98 FALSE
9 GTEx Breast Mammary Tissue (Female) CYBRD1 0.20 0.07 lasso 2 0.14 4.5e-05 9.5 -10.0 2.3e-23 -0.78 0.00 0.98 FALSE
10 GTEx Cells Transformed fibroblasts CYBRD1 0.34 0.16 enet 27 0.26 6.3e-20 6.8 -8.5 1.4e-17 -0.57 1.00 0.00 FALSE
11 GTEx Esophagus Muscularis CYBRD1 0.33 0.07 lasso 9 0.22 1.3e-13 7.9 -10.0 1.4e-23 -0.75 0.06 0.94 FALSE
12 GTEx Lung CYBRD1 0.14 0.05 enet 8 0.10 5.6e-08 -4.6 -7.9 3.9e-15 -0.45 0.98 0.01 FALSE
13 GTEx Muscle Skeletal CYBRD1 0.10 0.00 enet 9 0.01 1.5e-02 9.5 -9.2 3.5e-20 -0.71 0.00 0.99 FALSE
14 GTEx Nerve Tibial CYBRD1 0.36 0.07 lasso 10 0.20 2.3e-14 9.5 -9.9 5.5e-23 -0.73 0.00 1.00 FALSE
15 GTEx Thyroid CYBRD1 0.26 0.08 enet 26 0.12 1.4e-09 9.5 -9.1 8.1e-20 -0.72 0.00 1.00 FALSE
16 GTEx Uterus CYBRD1 0.54 0.04 lasso 6 0.19 1.1e-04 -6.0 -6.5 7.8e-11 -0.49 0.05 0.44 FALSE
17 GTEx Whole Blood CYBRD1 0.25 0.14 enet 19 0.15 1.4e-13 -4.5 -6.3 2.4e-10 -0.52 1.00 0.00 FALSE
18 METSIM Adipose CYBRD1 0.08 0.06 lasso 6 0.06 8.0e-09 -4.2 -6.3 3.2e-10 -0.48 0.92 0.08 FALSE
19 NTR Blood METTL8 0.03 0.02 lasso 7 0.02 1.7e-08 -4.2 5.5 4.3e-08 0.37 1.00 0.00 FALSE
20 ROSMAP Brain Pre-frontal Cortex CYBRD1 0.37 0.16 lasso 9 0.30 3.0e-39 7.1 -9.8 9.0e-23 -0.77 0.30 0.70 FALSE
21 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CYBRD1 0.14 0.04 enet 12 0.09 2.2e-05 11.6 9.7 3.2e-22 0.78 0.00 0.96 FALSE
22 The Cancer Genome Atlas Colon Adenocarcinoma CYBRD1 0.14 0.06 blup 69 0.05 6.4e-04 -5.5 6.6 4.0e-11 0.52 0.16 0.48 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma CYBRD1 0.03 0.02 lasso 3 0.03 4.5e-04 -5.0 -6.2 5.5e-10 -0.46 0.18 0.21 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma CYBRD1 0.08 0.06 blup 68 0.08 1.5e-08 7.1 -5.9 3.0e-09 -0.51 0.94 0.06 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma CYBRD1 0.10 0.06 lasso 4 0.06 6.2e-07 9.5 -11.2 2.8e-29 -0.86 0.00 1.00 TRUE