Best TWAS P=6.99e-09 · Best GWAS P=1.39e-08 conditioned to 0.00228
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | FYCO1 | 0.15 | 0.13 | lasso | 5 | 0.13 | 2.8e-05 | 5.2 | 5.8 | 7.0e-09 | 0.54 | 0.03 | 0.92 | TRUE |
| 2 | GTEx | Esophagus Muscularis | FYCO1 | 0.17 | 0.06 | lasso | 8 | 0.08 | 1.7e-05 | 4.0 | 5.2 | 2.3e-07 | 0.63 | 0.08 | 0.90 | FALSE |
| 3 | GTEx | Nerve Tibial | FYCO1 | 0.26 | 0.24 | enet | 25 | 0.27 | 2.8e-19 | 5.2 | 5.2 | 2.0e-07 | 0.50 | 0.03 | 0.97 | FALSE |
| 4 | GTEx | Whole Blood | CCR1 | 0.12 | 0.10 | lasso | 4 | 0.09 | 4.8e-09 | 5.0 | 5.5 | 5.2e-08 | 0.85 | 0.03 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | FYCO1 | 0.08 | 0.03 | enet | 12 | 0.04 | 8.1e-04 | 5.2 | 5.3 | 1.3e-07 | 0.48 | 0.01 | 0.94 | FALSE |