Best TWAS P=1.36e-11 · Best GWAS P=1.69e-13 conditioned to 2.96e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | -6.2 | -6.6 | 4.9e-11 | 0.76 | 0.82 | 0.18 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | -6.6 | -6.5 | 6.8e-11 | 0.50 | 0.54 | 0.45 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | -6.6 | -6.8 | 1.4e-11 | 0.59 | 0.30 | 0.68 | TRUE |