TWAS
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Genes
Traits
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Traits
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Impedance of leg (left)
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chr3:69,540,495-70,259,702
Best TWAS P=1.78e-07 · Best GWAS P=4.44e-09 conditioned to 0.00708
69.5M
69.6M
69.7M
69.8M
69.9M
70M
70.1M
70.2M
70.3M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Thyroid Carcinoma
MITF
0.12
0.08
lasso
6
0.09
1.8e-09
-5.7
-5.2
1.8e-07
0.91
0.02
0.98
TRUE