TWAS
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Traits
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Impedance of leg (left)
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chr3:127,639,072-129,090,995
Best TWAS P=6.59e-08 · Best GWAS P=1.47e-08 conditioned to 0.00307
127.6M
127.8M
128M
128.2M
128.4M
128.6M
128.8M
129M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Thyroid
RPN1
0.16
0.04
lasso
3
0.08
1.0e-06
4.6
5.4
6.6e-08
0.62
0.26
0.72
TRUE
1
GTEx
Testis
RPN1
0.30
0.15
enet
22
0.15
2.8e-07
4.5
5.2
1.8e-07
0.81
0.06
0.94
FALSE