TWAS hub - RPN1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1070	0.0280	4.9e-09	0.125	0.080	0.118	0.107	0.123	5.5e-15	5.6e-10	3.9e-14	6.4e-13	1.0e-14
2	GTEx	Adipose Subcutaneous	0.1390	0.0500	4.2e-05	0.040	NA	0.057	NA	0.019	3.2e-04	NA	1.9e-05	NA	1.0e-02
3	GTEx	Artery Aorta	0.1730	0.0570	1.4e-04	0.058	NA	0.071	NA	0.069	4.1e-04	NA	9.7e-05	NA	1.2e-04
4	GTEx	Artery Coronary	0.1490	0.0680	8.2e-03	0.052	NA	0.022	NA	0.032	7.5e-03	NA	6.0e-02	NA	3.0e-02
5	GTEx	Artery Tibial	0.1201	0.0392	1.2e-04	0.073	NA	0.031	NA	0.048	2.4e-06	NA	1.8e-03	NA	1.3e-04
6	GTEx	Brain Cortex	0.2950	0.0970	8.7e-04	0.145	NA	0.139	NA	0.148	8.4e-05	NA	1.2e-04	NA	7.0e-05
7	GTEx	Esophagus Gastroesophageal Junction	0.1310	0.0560	7.9e-03	0.102	NA	0.058	NA	0.077	1.6e-04	NA	3.8e-03	NA	9.9e-04
8	GTEx	Esophagus Muscularis	0.1870	0.0540	1.9e-05	0.106	NA	0.100	NA	0.104	5.5e-07	NA	1.1e-06	NA	7.3e-07
9	GTEx	Lung	0.0847	0.0322	8.5e-04	0.056	NA	0.030	NA	0.044	4.3e-05	NA	2.1e-03	NA	2.7e-04
10	GTEx	Testis	0.2960	0.0940	8.1e-06	0.154	NA	0.152	NA	0.133	2.5e-07	NA	2.8e-07	NA	1.8e-06
11	GTEx	Thyroid	0.1560	0.0510	2.7e-06	0.037	NA	0.076	NA	0.080	8.0e-04	NA	2.0e-06	NA	1.0e-06
12	METSIM	Adipose	0.0714	0.0258	3.3e-07	0.047	0.053	0.038	0.052	0.037	1.4e-07	2.3e-08	1.9e-06	3.1e-08	2.5e-06
13	NTR	Blood	0.0253	0.0120	2.2e-03	0.001	0.007	0.002	0.008	0.004	1.0e-01	1.9e-03	5.1e-02	8.6e-04	1.3e-02
14	YFS	Blood	0.1068	0.0270	3.3e-09	0.019	0.036	0.041	0.040	0.029	4.6e-07	6.5e-12	1.8e-13	3.7e-13	7.9e-10
15	TCGA	Brain Lower Grade Glioma	0.0618	0.0337	1.1e-04	0.038	0.037	0.035	NA	0.041	3.2e-05	4.8e-05	6.7e-05	NA	1.7e-05
16	TCGA	Liver Hepatocellular Carcinoma	0.1040	0.0830	3.1e-03	0.018	0.020	0.014	NA	0.008	4.6e-02	3.6e-02	6.9e-02	NA	1.4e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Blood Eosinophil Count	10.9	83.7	225.4	4.2	-10.2	7.0	-9.4	-8.1	15.0	-10.1	-11.0	-9.6	4.6	-8.4	10.2	-11.2	-2.7	5.9	-10.5
Ever had hysterectomy (womb removed)	5.2	5.9	10.9	1.5	2.8	3.3	2.9	2.8	2.3	2.8	2.5	2.5	2.5	2.8	2.7	1.8	1.3	1.5	1.8
Prostate Cancer	5.1	7.2	24.2	1.6	1.6	4.5	2.5	2.3	2.9	2.5	1.9	2.3	1.2	4.3	4.9	1.2	1.4	2.0	1.5
Alzheimer’s Disease (including proxy)	4.9	7.1	12.1	1.6	2.2	2.7	3.4	3.5	2.0	3.3	3.4	3.5	3.1	2.8	1.3	1.0	0.3	2.5	3.4
Blood White Count	4.9	36.0	97.2	-6.2	-3.8	-9.9	-4.8	-6.2	-7.8	-5.1	-5.8	-5.3	-5.4	-5.2	-9.4	0.8	-2.9	-4.1	-6.6
Time employed in main current job	4.8	5.5	10.4	2.2	3.2	2.8	2.2	2.5	2.3	2.4	2.6	2.3	2.9	2.0	2.1	0.6	0.0	2.5	2.7
Medication: Metformin	4.7	6.6	12.4	2.1	2.8	3.2	2.9	3.1	2.0	2.8	3.0	2.7	3.5	2.8	2.7	1.5	-0.3	2.1	1.8
Pain type(s) experienced in last month: Hip pain	4.7	5.9	9.7	-1.1	-2.8	-2.6	-2.8	-3.0	-2.0	-2.7	-2.9	-2.9	-2.8	-2.8	-2.1	-1.0	-1.2	-1.3	-3.1
Impedance of leg (left)	3.9	18.8	29.2	0.8	5.1	4.8	4.5	4.5	3.8	4.7	4.7	4.9	5.2	5.4	4.0	4.3	3.3	1.8	4.6
Had other major operations	3.7	4.5	10.0	-1.1	-2.4	-2.8	-2.6	-2.2	-1.6	-2.4	-2.2	-2.6	-1.7	-3.2	-2.2	-0.8	-0.3	-1.3	-2.5
Birth weight	3.5	7.7	13.8	-3.2	-1.5	-2.5	-2.8	-2.9	-1.1	-3.1	-3.3	-3.3	-2.9	-2.8	-3.1	-0.0	2.5	-3.1	-3.7
Leg fat-free mass (left)	3.2	17.2	29.5	-1.4	-4.5	-4.9	-4.4	-4.6	-3.3	-5.0	-4.7	-4.9	-5.4	-5.1	-3.7	-2.6	-0.9	-2.3	-4.8
Heel bone mineral density (BMD) T-score, automated (left)	3.1	7.0	14.1	1.5	3.8	2.2	3.3	3.2	1.1	3.1	3.2	3.3	3.2	3.1	1.9	1.4	0.8	1.4	3.2
Qualifications: CSEs or equivalent	3.1	4.1	6.4	-1.5	-2.2	-2.0	-2.2	-2.4	-2.0	-2.2	-2.2	-2.2	-2.5	-2.3	-1.7	-1.9	-1.5	-1.3	-1.8
Leg predicted mass (left)	3.1	16.5	28.6	-1.3	-4.4	-4.9	-4.3	-4.5	-3.3	-4.9	-4.6	-4.9	-5.3	-5.0	-3.6	-2.5	-0.9	-2.2	-4.7
Neuroticism score	2.9	6.1	9.8	1.9	2.3	2.2	3.1	2.8	1.5	2.7	3.1	3.0	2.9	2.9	1.9	2.4	-0.3	2.1	2.7
Had major operations	2.9	3.4	5.3	2.3	1.0	1.4	2.3	2.2	1.7	2.2	2.1	2.1	1.8	1.9	1.8	1.3	-0.8	1.8	1.9
Leg fat-free mass (right)	2.9	15.3	27.5	-1.3	-4.3	-4.7	-4.1	-4.3	-3.0	-4.7	-4.4	-4.7	-5.2	-4.8	-3.7	-2.2	-0.6	-2.2	-4.4
Wears glasses or contact lenses	2.9	3.3	4.9	1.3	1.8	2.1	1.8	2.0	1.2	2.2	2.1	1.7	2.2	2.2	1.8	1.2	-1.1	1.8	1.8
Heel T-Score	2.8	22.0	43.3	3.0	6.2	4.8	4.9	5.0	3.5	4.9	5.3	5.3	6.6	5.1	4.4	3.0	-0.3	3.8	5.1
Impedance of leg (right)	2.8	13.6	22.9	0.6	4.4	4.2	3.7	3.8	2.9	4.0	3.9	4.3	4.5	4.8	3.9	3.6	2.6	1.5	3.7
Stomach or abdominal pain in last month	2.8	3.5	5.8	2.1	1.0	2.3	2.2	2.2	1.2	2.4	2.2	2.0	1.7	2.0	2.1	0.2	-0.9	1.9	1.9
Medication: Levothyroxine sodium	2.8	4.7	7.0	-1.8	-2.0	-1.9	-2.4	-2.4	-2.3	-2.6	-2.4	-2.6	-2.6	-2.1	-1.7	-1.0	-0.4	-2.4	-2.6
Heel bone mineral density (BMD) T-score, automated (right)	2.8	6.4	12.3	1.3	3.5	2.1	3.1	3.2	0.3	3.0	3.2	3.5	3.2	2.8	1.9	0.7	0.8	1.2	3.0
Handedness (chirality/laterality): Left-handed	2.8	3.4	6.0	1.0	1.2	2.0	2.5	2.1	1.9	2.5	2.0	2.2	1.1	2.3	1.9	2.1	0.8	1.0	1.9
Diabetes diagnosed by doctor	2.8	4.6	7.0	2.0	2.4	1.9	2.6	2.6	1.2	2.4	2.6	2.4	2.4	2.3	1.9	2.0	-0.0	1.8	2.1
Leg predicted mass (right)	2.8	14.9	27.0	-1.2	-4.3	-4.7	-4.1	-4.3	-2.9	-4.6	-4.3	-4.6	-5.2	-4.7	-3.7	-2.2	-0.6	-2.2	-4.3
Depressed Affect (Nagel 2018)	2.7	5.6	11.8	0.9	2.3	1.7	3.3	3.4	0.2	3.2	3.3	3.4	1.8	3.0	1.0	2.0	1.2	0.7	2.3
Commuting to job workplace: Walk	2.6	2.8	5.1	-1.3	-0.9	-2.3	-2.2	-2.1	-1.9	-1.9	-1.7	-2.0	-2.2	-1.6	-1.5	-0.5	-1.0	-1.3	-1.2
Blood Platelet Count	2.5	28.9	66.3	6.2	3.1	6.0	5.8	5.5	6.5	5.5	5.2	5.7	8.1	2.1	3.4	0.8	-3.8	7.8	5.0
Worrier / anxious feelings	2.5	4.8	8.5	2.7	1.9	1.9	2.7	2.5	1.3	2.2	2.6	2.5	2.5	1.8	1.5	0.1	-0.7	2.9	2.9
BMI	2.4	13.7	28.3	-1.6	-4.1	-5.0	-3.2	-3.5	-3.7	-3.7	-3.4	-3.6	-4.2	-4.8	-5.3	-3.1	-2.1	-2.4	-3.6
Neuroticism	2.4	5.9	10.0	1.5	2.4	1.9	3.2	3.0	1.1	2.8	3.1	3.0	3.0	2.9	1.6	2.5	-0.2	1.9	2.6
Qualifications: O levels/GCSEs or equivalent	2.2	3.4	5.9	-1.7	-2.1	-2.4	-1.9	-2.2	-1.3	-2.2	-2.3	-2.4	-2.4	-0.5	-0.3	0.6	0.2	-1.9	-2.3
Irritability	2.2	3.7	7.1	1.1	1.6	1.5	2.4	2.4	0.2	2.5	2.5	2.6	1.6	2.7	1.2	2.0	-0.3	0.9	2.5
Ever had prostate specific antigen (PSA) test	2.2	2.5	11.5	1.2	1.3	2.2	1.4	1.6	1.4	1.3	1.3	1.4	1.4	1.7	3.4	0.0	0.7	1.4	1.2
Medication: Ramipril	2.0	2.5	4.5	1.6	1.3	1.9	2.0	2.0	1.6	1.8	2.1	2.1	2.0	0.8	-0.2	0.4	-0.6	1.4	1.8
Medication: Blood pressure	2.0	3.5	9.2	1.6	2.0	1.7	2.0	2.3	2.1	2.1	2.3	2.2	3.0	1.1	0.2	0.8	-0.6	2.0	1.7
Cholesterol lowering medication	2.0	2.9	8.1	-1.6	-1.5	-2.1	-1.3	-1.4	-2.9	-1.4	-1.3	-1.4	-2.1	-1.6	-2.1	-0.7	-1.2	-1.9	-1.7
Body mass index (BMI)	1.9	7.9	18.9	-0.8	-3.0	-3.9	-2.4	-2.6	-2.7	-2.6	-2.5	-2.8	-3.0	-3.9	-4.3	-1.7	-2.0	-1.5	-2.9
Arm fat mass (right)	1.9	7.9	15.9	-1.4	-3.0	-4.0	-2.5	-2.6	-2.8	-2.8	-2.6	-2.9	-3.5	-3.7	-3.8	-1.1	-0.9	-2.1	-3.1
Whole body fat-free mass	1.9	11.0	20.2	-0.6	-3.5	-3.8	-3.5	-3.7	-2.2	-4.0	-3.8	-4.1	-4.5	-4.3	-3.0	-2.0	-0.4	-1.5	-4.0
Qualifications: nursing, teaching	1.9	3.0	4.9	-1.9	-1.6	-1.9	-1.9	-2.1	-1.9	-1.9	-2.2	-2.2	-1.9	-0.8	-0.9	-0.2	-0.6	-1.9	-2.0
Basal metabolic rate	1.9	10.7	19.4	-0.7	-3.5	-4.0	-3.3	-3.5	-2.4	-3.9	-3.7	-4.0	-4.4	-4.2	-3.3	-1.8	-0.3	-1.6	-3.9
Weight	1.8	8.9	17.2	-1.0	-3.2	-4.2	-2.8	-3.0	-2.3	-3.3	-3.1	-3.4	-3.8	-3.9	-3.8	-0.9	-0.2	-1.8	-3.4
Tense / ‘highly strung’	1.8	3.0	5.6	1.8	0.8	1.7	1.5	1.3	2.1	1.4	1.5	1.6	2.3	2.0	2.1	1.7	-0.4	2.1	2.4
Medication: Allopurinol	1.8	2.4	6.7	-0.9	-1.1	-2.1	-1.5	-1.8	-2.6	-1.7	-1.7	-1.7	-1.4	-1.5	-1.7	-0.1	-1.0	-1.1	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	6.0	-2.0	-0.5	-2.5	-1.0	-1.0	-1.4	-1.0	-0.8	-0.9	-1.3	-1.1	-2.5	1.1	1.3	-2.0	-0.7
Whole body water mass	1.8	10.4	20.2	-0.5	-3.5	-3.7	-3.3	-3.5	-2.2	-3.9	-3.7	-4.0	-4.5	-4.2	-3.0	-2.0	-0.3	-1.4	-3.8
Arm fat mass (left)	1.8	7.3	15.1	-1.2	-2.8	-3.9	-2.3	-2.5	-2.7	-2.6	-2.5	-2.7	-3.4	-3.6	-3.9	-1.1	-0.9	-1.9	-2.9
Average weekly beer plus cider intake	1.8	2.6	6.6	0.7	-2.2	-1.5	-1.6	-1.6	-0.9	-1.7	-1.6	-1.4	-1.0	-2.4	-1.3	-1.8	-2.6	0.3	-1.8
Primary Biliary Cirrhosis	1.7	2.5	8.9	-2.3	-0.9	-1.7	-1.4	-1.3	-3.0	-1.3	-1.3	-0.9	-1.9	-0.9	-1.2	0.1	-0.4	-2.2	-1.7
Diabetes (self-reported)	1.7	2.6	4.6	1.8	1.8	1.4	1.8	1.9	0.8	1.7	2.1	1.8	1.9	1.6	1.3	1.4	-0.1	1.4	1.9
Length of working week for main job	1.7	1.8	6.3	0.3	2.5	1.1	1.4	1.6	0.6	1.7	1.5	1.6	1.4	1.6	0.8	1.5	0.5	0.8	1.0
Medication for cholesterol	1.7	2.6	6.6	0.9	2.2	2.0	1.3	1.6	1.4	1.7	1.3	1.8	1.6	2.2	2.6	1.0	1.1	1.0	1.2
Miserableness	1.7	2.9	5.5	1.7	1.1	1.4	1.8	2.0	0.6	1.8	1.8	2.0	1.1	2.3	2.3	2.3	0.9	1.4	1.4
Lung FEV1/FVC ratio	1.6	8.1	41.0	0.8	2.2	1.2	1.3	1.5	0.2	1.2	1.1	1.2	0.3	6.4	5.6	6.4	0.8	0.7	-0.1
Arm fat percentage (right)	1.6	6.3	15.2	-1.8	-2.5	-3.9	-2.0	-2.1	-2.9	-2.2	-2.1	-2.2	-2.5	-3.2	-3.8	-1.0	-1.2	-2.4	-2.6
Hip circumference	1.6	6.7	16.1	-1.5	-3.2	-4.0	-2.2	-2.3	-2.8	-2.5	-2.4	-2.5	-3.5	-2.7	-3.0	-0.1	0.1	-2.4	-2.7
Arm fat percentage (left)	1.6	6.5	16.1	-1.8	-2.5	-4.0	-2.0	-2.2	-3.0	-2.2	-2.1	-2.3	-2.7	-3.1	-3.9	-0.9	-1.1	-2.4	-2.5
Medication: Blood pressure	1.6	3.1	8.1	-0.1	-2.4	-1.6	-1.6	-1.8	-1.3	-1.8	-1.4	-1.8	-1.0	-2.8	-2.0	-2.4	-2.3	-0.3	-1.0
Impedance of whole body	1.6	7.9	17.5	-0.6	2.7	3.0	2.5	2.6	2.4	2.8	2.6	2.9	2.8	4.2	3.5	3.5	3.3	0.1	2.9
Basal cell carcinoma (self-reported)	1.5	1.7	3.4	0.6	1.8	0.9	1.8	1.6	0.2	1.5	1.3	1.8	0.4	1.7	1.4	0.5	1.4	0.6	1.8
Medication: Co-codamol	1.4	1.6	4.7	-0.3	-2.2	-1.6	-1.0	-1.2	-1.0	-0.9	-1.1	-0.9	-1.4	-1.7	-1.8	-1.1	-0.4	-0.8	-1.4
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.9	-1.0	-1.4	-0.6	-1.6	-1.5	-0.3	-1.4	-1.6	-1.8	-1.1	-1.1	-0.8	-0.6	0.4	-0.8	-2.0
Medication: Amlodipine	1.4	2.0	4.0	1.8	1.6	0.3	1.5	1.3	0.5	1.6	1.6	1.5	1.7	1.0	0.0	1.3	-2.0	1.9	1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	5.2	-0.2	1.4	1.4	1.3	1.5	0.2	1.7	1.3	1.4	1.0	2.3	1.6	0.4	-0.2	-0.4	1.3
Mood swings	1.4	2.6	5.3	0.2	2.0	1.4	2.2	2.3	-0.2	2.2	2.3	2.2	1.0	2.2	0.9	1.2	0.4	-0.1	1.7
Neuroticism (Nagel 2018)	1.3	3.2	6.9	1.2	1.1	1.2	2.4	2.5	0.3	2.3	2.6	2.5	1.7	2.0	1.0	1.1	0.2	1.0	2.4
Crohns Disease (2017)	1.3	2.9	6.7	-1.1	-1.3	-1.5	-2.1	-1.9	-0.7	-2.2	-1.8	-1.8	-1.2	-2.6	-1.6	-2.4	0.0	-1.2	-1.9
Waist circumference	1.3	4.7	13.2	-0.2	-2.4	-3.4	-1.8	-2.0	-1.9	-2.0	-1.8	-2.1	-2.2	-3.2	-3.6	-0.2	-1.2	-0.8	-2.4
Trunk fat-free mass	1.3	7.2	13.3	-0.1	-2.6	-3.0	-2.7	-3.0	-1.7	-3.3	-3.2	-3.4	-3.7	-3.6	-2.5	-1.7	-0.2	-0.9	-3.3
Loud music exposure frequency	1.3	1.5	3.9	-0.2	-2.0	-1.5	-1.3	-1.3	-1.2	-1.2	-1.3	-1.2	-1.7	-1.1	-1.2	-0.4	-1.0	-0.2	-1.0
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	6.4	0.4	-0.7	-1.1	-0.8	-1.1	-2.1	-1.2	-1.1	-1.1	-1.2	-1.1	0.0	-1.9	-2.5	-0.0	-1.0
Whole body fat mass	1.3	5.4	13.6	-1.2	-2.1	-3.7	-2.0	-2.2	-2.3	-2.3	-2.1	-2.4	-2.7	-2.9	-3.5	-0.3	-0.3	-1.8	-2.6
Alcohol intake frequency.	1.3	3.1	5.1	2.0	1.6	1.8	2.1	2.0	1.4	2.1	2.3	2.1	2.1	1.4	0.5	-0.7	-1.3	1.7	1.9
Medication: Aspirin	1.3	1.7	4.1	2.0	1.1	1.2	1.5	1.4	1.6	1.3	1.6	1.4	1.1	0.5	0.3	0.1	-0.0	1.9	1.6
Loneliness, isolation	1.3	1.9	5.0	0.2	1.2	1.0	1.9	1.9	-0.2	2.1	2.2	2.1	0.2	1.3	-0.3	0.5	0.2	-0.1	2.0
Myopia	1.3	1.8	4.1	-1.0	-1.0	-1.9	-1.7	-1.7	-0.4	-1.9	-1.6	-1.5	-1.1	-1.5	-2.0	-1.0	0.2	-0.7	-0.7
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	3.8	-0.3	-1.9	-1.4	-1.3	-1.4	-0.6	-1.1	-1.3	-1.3	-1.3	-1.9	-1.2	-1.6	-0.5	-1.0	-1.2
Body Mass Index (BMI) (2010)	1.2	1.7	4.5	-1.3	-0.1	-1.5	-1.3	-1.3	-1.5	-1.2	-1.2	-1.2	-0.4	-1.3	-1.9	-2.1	-0.4	-1.1	-1.4
Coronary Artery Disease (CAD)	1.2	1.4	5.8	1.3	1.2	-0.2	1.3	1.0	0.4	0.9	0.8	1.4	0.9	1.4	1.0	2.4	-0.4	1.3	0.9
Medication: Lansoprazole	1.2	1.4	3.3	-1.6	-0.2	-1.4	-0.8	-0.8	-1.6	-0.9	-0.7	-0.7	-1.3	-1.3	-1.8	0.2	0.7	-1.6	-1.5
Trunk predicted mass	1.2	6.7	12.8	-0.1	-2.6	-2.9	-2.6	-2.9	-1.5	-3.2	-3.1	-3.4	-3.6	-3.5	-2.4	-1.6	-0.2	-0.8	-3.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	4.0	-1.7	-1.5	-1.5	-1.5	-1.5	-0.2	-1.4	-1.5	-1.6	-0.7	-1.2	-1.6	-0.8	0.5	-1.5	-2.0
Birth weight of first child	1.2	2.2	5.8	-1.9	-0.1	-0.8	-1.2	-1.0	-1.5	-1.3	-1.2	-1.7	-2.4	-0.6	-0.9	-0.7	2.4	-1.9	-1.5
Peak expiratory flow (PEF)	1.2	2.7	5.6	-1.7	-1.7	-1.8	-1.7	-1.6	0.2	-1.9	-1.9	-2.0	-2.4	-0.8	-0.7	1.4	1.6	-2.1	-1.3
Blood clot in the leg (DVT)	1.2	1.6	3.6	-0.2	-1.8	-1.2	-1.2	-1.4	-0.6	-1.1	-1.3	-1.3	-1.2	-1.9	-1.1	-1.8	-0.7	-0.8	-1.4
Number of full brothers	1.2	1.5	6.2	-0.6	-0.8	-1.5	-0.5	-0.8	-1.9	-0.7	-0.7	-0.6	-0.5	-1.7	-2.5	-1.3	-1.0	-1.0	-1.7
Pulse rate, automated reading	1.2	3.8	10.8	2.0	1.7	1.8	1.5	1.6	1.4	1.8	1.4	1.5	2.4	2.6	3.3	2.4	-1.0	2.5	0.8
Friendships satisfaction	1.2	1.5	4.4	0.6	2.0	0.9	1.4	1.4	1.1	1.4	1.5	1.4	2.1	0.5	0.4	0.7	0.2	0.7	1.2
Medication: Atorvastatin	1.2	1.4	3.7	0.9	0.3	1.9	1.2	1.3	1.8	1.4	1.4	1.3	1.2	1.2	0.9	0.0	0.2	1.2	1.1
Illnesses of father: High blood pressure	1.2	1.5	3.5	0.6	1.4	0.7	1.7	1.4	0.5	1.2	1.8	1.7	1.6	0.5	-0.8	1.1	0.5	0.8	1.9
Respiratory disease	1.1	2.3	13.7	0.6	-2.4	0.2	-0.8	-0.9	0.7	-1.1	-0.7	-1.2	-0.3	-2.9	-1.7	-3.7	-1.0	0.5	0.1
Trunk fat mass	1.1	4.5	11.4	-1.3	-2.0	-3.4	-1.9	-2.1	-1.8	-2.2	-1.9	-2.3	-2.6	-2.5	-3.0	0.2	0.2	-1.7	-2.3
Alcohol usually taken with meals	1.1	1.7	9.2	-2.5	1.8	-0.6	-0.1	-0.1	-0.7	-0.2	-0.3	-0.4	-1.1	1.0	-1.1	0.4	3.0	-2.0	-0.7
Number of live births	1.1	1.6	7.4	-1.2	-1.3	-0.3	-1.4	-1.2	0.4	-1.3	-1.3	-1.2	-0.5	-1.8	-1.1	-2.7	0.3	-0.9	-0.9
Arm fat-free mass (right)	1.1	5.5	11.8	-0.0	-2.4	-2.5	-2.3	-2.5	-1.4	-2.8	-2.6	-3.0	-3.4	-3.2	-2.3	-1.2	-0.0	-0.7	-3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.6	-1.1	-1.6	-0.9	-1.1	-1.0	-1.6	-1.2	-0.9	-1.1	-1.5	-1.0	-0.5	-1.5	-0.2	-1.5	-0.7
Leg fat mass (right)	1.1	4.4	11.8	-0.7	-1.7	-3.2	-1.7	-1.9	-2.3	-2.0	-1.7	-2.0	-2.0	-3.0	-3.4	-0.5	-1.2	-1.2	-2.4
Arm predicted mass (right)	1.1	5.8	11.8	-0.1	-2.4	-2.6	-2.5	-2.7	-1.3	-3.0	-2.8	-3.1	-3.3	-3.4	-2.3	-1.4	-0.1	-0.7	-3.0
Number of full sisters	1.1	1.3	6.0	2.3	-0.3	0.4	0.5	0.6	0.9	0.6	0.8	0.5	1.2	0.5	0.5	-0.1	-2.5	2.0	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	3.8	-0.6	-2.0	-0.6	-1.3	-1.1	-0.2	-1.5	-1.2	-1.5	-0.9	-1.7	-0.5	0.0	-0.3	-1.1	-1.4
Average weekly champagne plus white wine intake	1.1	1.6	5.8	-2.4	0.9	-0.5	-0.9	-0.7	-1.7	-0.6	-0.6	-0.6	-1.4	0.3	-0.5	0.5	1.9	-2.1	-1.6
Hearing aid user	1.1	1.2	4.3	-0.1	-1.1	-1.6	-1.2	-1.1	-2.1	-1.1	-1.1	-1.2	-0.7	-0.9	-0.3	-0.5	-1.5	-0.7	-0.9
Arm fat-free mass (left)	1.1	5.4	11.6	0.1	-2.3	-2.6	-2.2	-2.4	-1.6	-2.8	-2.5	-2.9	-3.3	-3.4	-2.5	-1.2	-0.2	-0.7	-2.8
Arm predicted mass (left)	1.1	5.7	12.6	0.1	-2.3	-2.6	-2.4	-2.5	-1.3	-2.9	-2.7	-3.0	-3.2	-3.5	-2.5	-1.5	-0.1	-0.6	-3.0
Worry (Nagel 2018)	1.0	2.2	5.1	1.5	0.8	1.1	1.5	1.5	0.6	1.5	1.8	1.8	2.3	1.4	1.1	-0.3	-1.5	1.9	2.0
Rheumatoid Arthritis	1.0	1.4	5.4	0.5	-1.1	1.1	-0.7	-0.3	1.8	-0.5	-0.4	-0.6	1.9	0.2	2.3	-1.9	-1.1	1.1	0.1
Angina	1.0	1.4	3.5	1.9	0.7	0.9	1.4	1.4	1.1	1.3	1.4	1.4	1.1	0.7	0.4	0.7	-0.2	1.5	1.2
Hearing difficulty/problems with background noise	1.0	1.6	3.9	0.9	-0.2	2.0	1.1	1.6	1.2	1.4	1.3	1.5	1.3	1.2	1.8	-0.6	-0.5	0.8	1.1
Pain all over the body in last month	1.0	1.0	2.0	0.7	0.8	0.8	1.4	1.4	0.7	1.3	1.3	1.3	1.2	1.2	0.7	0.7	0.4	0.4	0.9
Noisy workplace	1.0	1.2	2.7	1.5	0.3	0.1	1.2	1.1	0.9	1.2	1.4	1.1	1.1	1.1	0.1	0.7	-1.0	1.5	1.6
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	4.7	-0.7	-1.1	-1.1	-1.4	-1.7	-1.5	-1.5	-1.8	-1.7	-2.2	-0.8	0.3	-0.6	-0.7	-0.8	-1.2
Gout (self-reported)	1.0	1.4	2.9	-0.6	-0.6	-1.1	-1.5	-1.5	-1.4	-1.5	-1.4	-1.7	-0.8	-1.4	-1.1	-0.5	-0.6	-0.8	-1.2
Eye problems/disorders: Cataract	1.0	1.1	4.7	-2.2	-0.3	-0.9	-0.1	-0.2	-1.8	-0.0	-0.2	-0.3	-0.9	-0.1	-1.3	-1.1	1.4	-1.8	-0.7
Asthma (self-reported)	1.0	2.1	12.4	0.0	-1.5	-0.1	-0.8	-0.8	0.0	-1.0	-0.4	-0.9	0.3	-2.8	-2.1	-3.5	-1.6	0.1	-0.1
Medication: Aspirin	1.0	1.3	2.6	1.6	1.1	1.1	1.3	1.3	1.4	1.2	1.5	1.3	0.8	0.4	0.4	-0.0	0.1	1.5	1.5
Commuting to job workplace: Public transport	1.0	1.1	3.2	0.8	0.7	1.1	0.8	1.0	1.5	1.1	1.1	1.1	1.1	1.4	1.0	0.2	-0.5	1.0	1.8
Alcohol drinker status: Never	1.0	1.2	6.5	1.5	-0.2	1.2	-0.4	-0.4	0.4	-0.5	-0.2	-0.2	0.3	-1.2	0.7	-1.9	-2.5	1.5	0.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	4.7	-0.8	-1.1	-1.8	-0.8	-0.8	-1.3	-0.5	-0.7	-0.7	-0.0	-0.4	-1.6	-0.9	-2.2	-1.0	-0.3
Intelligence (Savage-Jansen 2018)	0.9	2.7	5.6	1.4	1.1	1.1	1.5	1.7	1.5	1.5	1.4	1.8	1.0	2.2	2.3	2.4	1.4	1.3	1.8
Age at First Birth	0.9	1.3	4.8	0.6	2.2	1.8	1.3	1.3	0.6	1.1	1.2	1.1	0.5	1.0	1.0	-0.1	1.3	1.1	0.6
Mean Putamen Volume	0.9	1.0	5.0	-0.2	0.6	-1.5	-0.7	-0.9	-2.2	-0.6	-0.6	-0.3	0.0	-1.2	-1.6	0.2	-1.3	-0.0	-0.8
Diabetes (mother)	0.9	1.1	2.5	0.6	-0.5	-0.9	-1.0	-1.2	0.2	-1.2	-1.0	-1.3	0.5	-1.6	-1.2	-1.2	-1.6	1.0	-0.9
Trunk fat percentage	0.9	3.4	9.2	-1.6	-1.7	-3.0	-1.6	-1.7	-1.8	-1.7	-1.5	-1.8	-2.2	-1.8	-2.5	0.7	0.5	-2.0	-1.9
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	3.0	1.4	0.5	0.6	0.6	0.7	1.0	0.4	0.8	0.4	1.7	0.8	1.5	1.4	-0.3	1.4	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.8	1.3	1.3	1.1	1.2	1.4	0.6	1.2	1.4	1.2	1.1	1.2	1.9	0.4	1.1	1.2	1.1
Pulse rate	0.9	1.5	6.7	0.4	1.5	0.2	1.3	1.4	-0.3	1.4	1.1	1.1	1.4	1.9	1.1	2.6	0.2	0.4	0.2
Asthma	0.9	1.8	9.2	-0.1	-1.5	-0.1	-0.8	-0.8	0.3	-0.9	-0.4	-0.9	0.3	-2.8	-2.1	-3.0	-1.1	-0.0	-0.0
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.2	-1.9	-0.8	-1.1	-0.7	-0.5	-1.0	-0.4	-0.8	-0.7	-1.3	-0.1	-0.9	0.2	1.2	-2.0	-0.7
Headache pain in last month	0.9	1.5	4.1	0.5	1.6	1.9	0.8	1.2	0.9	1.1	1.6	0.9	1.3	1.2	2.0	-0.0	1.4	0.9	0.9
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	5.3	-1.5	-1.4	-1.0	-1.0	-0.9	-2.1	-1.1	-1.1	-1.2	-2.1	-0.8	-1.0	-0.5	-0.3	-2.3	-1.0
Emphysema/chronic bronchitis	0.9	1.0	4.4	-1.1	-2.1	-0.7	-0.9	-1.0	-0.4	-0.8	-1.0	-1.0	-1.6	-0.2	-0.4	0.0	0.8	-1.4	-0.1
Illnesses of siblings: Diabetes	0.9	1.1	2.1	0.7	1.4	0.4	1.3	1.1	-0.7	1.2	1.2	1.3	1.3	0.4	-0.1	-1.1	-1.4	0.9	0.7
Medication: Lisinopril	0.9	1.1	3.3	1.8	-0.8	1.4	0.7	0.8	1.6	0.8	0.5	0.5	0.9	-0.1	1.3	-0.8	-1.2	1.5	0.8
Leg fat mass (left)	0.9	3.4	11.5	-0.4	-1.5	-2.9	-1.4	-1.6	-1.8	-1.8	-1.4	-1.8	-1.7	-2.8	-3.4	-0.4	-0.8	-0.9	-1.9
Schizophrenia vs Biploar Disorder	0.8	1.0	4.9	0.7	1.6	0.0	0.4	0.4	1.3	0.6	0.8	0.5	2.2	0.8	-0.1	1.5	0.1	1.0	1.1
Crohns Disease (2012)	0.8	1.3	6.5	-0.3	-0.2	-0.8	-1.4	-1.2	0.0	-1.5	-1.1	-1.0	0.3	-2.1	-0.6	-2.5	-0.3	0.2	-0.7
Allergy or Eczema	0.8	2.1	7.6	2.3	0.0	2.5	0.1	0.5	2.8	-0.2	0.1	-0.2	1.5	-0.4	2.1	-1.1	-0.3	2.3	0.6
Hypothyroidism (self reported)	0.8	1.9	6.8	-1.9	-1.5	-0.9	-0.8	-0.9	-1.9	-1.1	-1.1	-1.1	-2.2	-0.7	-1.1	-0.5	0.9	-2.6	-1.2
Relative age of first facial hair	0.8	1.6	4.7	1.6	0.6	2.0	1.0	0.9	0.9	0.9	1.1	1.1	0.5	1.2	2.2	-0.7	-0.6	1.4	1.8
Systolic blood pressure, automated reading	0.8	2.4	18.6	2.5	0.3	-0.2	0.5	-0.0	0.4	0.3	0.2	0.6	1.7	-0.9	-0.3	-0.3	-4.3	2.9	0.6
Maternal smoking around birth	0.8	1.1	3.7	0.7	-1.7	-1.6	-0.8	-1.1	-0.8	-1.0	-0.9	-0.7	-0.8	-0.8	-1.2	-0.6	-1.9	0.4	0.0
Illnesses of siblings	0.8	1.2	2.5	-0.9	-1.5	0.0	-1.3	-1.3	0.8	-1.3	-1.6	-1.1	-1.1	0.1	1.1	-0.3	1.6	-0.9	-0.7
Illnesses of mother	0.8	1.0	2.5	-1.6	0.1	-0.7	-1.1	-0.9	-1.3	-0.9	-1.0	-0.5	-1.0	-0.1	-0.4	0.9	1.2	-1.5	-1.3
Body fat percentage	0.8	3.1	9.2	-1.5	-1.4	-3.0	-1.3	-1.4	-2.0	-1.4	-1.2	-1.5	-1.8	-1.9	-3.0	0.4	0.1	-1.9	-1.8
Angina (self-reported)	0.8	1.0	2.0	1.4	0.6	0.8	1.2	1.3	0.9	1.3	1.4	1.4	1.1	0.6	0.3	0.7	0.1	1.0	1.1
Ever had bowel cancer screening	0.8	0.9	4.3	-1.9	-0.8	-0.6	-0.4	-0.3	-1.3	-0.1	-0.3	-0.4	-0.5	-0.8	-1.3	-0.5	-0.3	-2.1	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	1.9	-0.7	-1.0	-1.3	-1.3	-1.1	-0.4	-1.4	-1.0	-1.1	-0.2	-1.1	-0.9	-0.7	0.1	-0.5	-0.9
Ovarian Cancer	0.7	1.0	2.3	-0.8	-0.4	-1.3	-0.8	-0.8	-1.5	-0.5	-0.7	-0.6	-0.9	-0.9	-1.4	-1.3	-1.4	-0.5	-0.9
HDL Cholesterol	0.7	1.2	4.9	0.3	0.6	1.3	1.2	1.2	0.8	1.2	1.4	1.3	-0.1	1.4	0.5	2.2	0.8	0.4	1.1
Schizophrenia (2014)	0.7	1.6	5.7	1.1	1.2	0.8	1.1	1.0	1.8	0.9	1.3	1.4	2.1	0.2	0.1	-0.0	0.5	1.3	2.4
Triglycerides	0.7	1.1	2.5	-0.6	-0.2	-1.4	-1.1	-1.3	-1.3	-1.2	-1.2	-1.3	-0.9	-0.7	-0.6	-0.1	-1.0	-0.7	-1.6
Cardiovascular Disease	0.7	2.3	8.1	0.8	-2.3	-1.1	-0.6	-1.1	-0.4	-1.1	-0.9	-1.0	-0.3	-2.3	-2.7	-2.1	-2.8	0.4	-0.9
Hearing difficulty/problems: Yes	0.7	1.0	2.5	0.5	-0.1	0.9	1.1	1.4	0.6	1.1	1.3	1.1	1.2	1.0	0.8	0.9	-0.7	0.5	1.6
Diabetes (father)	0.7	0.9	2.5	-0.2	1.6	0.5	0.9	1.2	-1.2	0.9	1.2	1.2	0.9	0.6	0.5	0.5	-0.0	-0.1	1.5
High blood pressure	0.7	1.8	11.6	1.9	-0.1	0.2	0.4	0.4	0.1	0.3	0.7	0.2	1.6	-1.6	-1.5	-1.6	-3.4	1.7	0.3
Chronic bronchitis/emphysema (father)	0.7	0.8	2.9	1.0	-1.2	0.0	-0.5	-0.5	0.8	-0.7	-0.4	-0.5	0.4	-1.7	0.3	-1.0	-1.6	1.0	-0.6
Medication: Simvastatin	0.7	1.0	2.0	-1.1	-1.1	-1.4	-1.0	-0.9	-1.4	-1.0	-0.8	-1.0	-1.0	-0.8	-1.1	0.0	0.0	-1.3	-1.1
Prospective memory result	0.7	0.8	2.3	0.6	0.5	0.0	1.1	1.0	0.2	1.3	1.2	0.9	0.9	0.8	-0.2	1.5	-0.1	1.1	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	10.0	1.0	0.2	0.7	0.4	0.6	2.1	0.3	0.1	0.2	-0.1	2.2	2.7	3.2	1.9	1.0	0.4
Glaucoma (self-reported)	0.7	0.8	1.6	0.8	1.0	1.2	1.1	0.9	1.1	0.8	0.8	1.0	0.3	0.5	1.3	0.7	0.5	0.7	1.1
Medication: Ventolin 100micrograms inhaler	0.7	0.9	5.2	-0.3	-2.3	-0.2	-0.5	-0.7	-0.3	-0.6	-0.5	-0.6	-1.0	-1.7	-1.0	-1.4	-0.5	-0.6	-0.2
Number of children fathered	0.7	0.8	5.6	-0.1	0.3	-0.2	1.0	1.0	0.5	0.7	0.6	0.6	1.0	0.9	-0.0	2.4	1.3	-0.1	0.3
Qualifications: College or University degree	0.7	2.2	8.6	-0.1	1.8	1.3	1.6	1.6	0.1	1.8	1.1	1.6	1.0	2.9	2.0	1.4	1.2	0.3	1.5
Medication for pain relief, constipation, heartburn	0.7	1.1	2.9	-1.7	-0.3	-0.6	-1.3	-1.4	-1.0	-1.3	-1.5	-1.5	-0.5	-0.0	0.1	-0.8	-0.2	-1.3	-1.2
Heart disease (mother)	0.7	0.9	2.9	1.2	0.1	1.1	0.9	0.9	0.5	0.9	1.0	0.7	1.0	0.0	0.7	-1.5	-1.7	0.7	0.8
Supplements: Vitamin C	0.7	0.9	3.4	-1.7	1.2	-0.1	0.6	0.6	-1.1	0.8	0.6	0.6	-0.2	1.2	-0.3	0.7	0.9	-1.9	0.1
Hypertension (Self-reported)	0.7	2.0	14.2	1.6	-0.7	-0.2	-0.1	-0.2	-0.3	-0.3	0.1	-0.4	1.2	-2.1	-1.5	-2.0	-3.8	1.6	-0.3
Number of self-reported non-cancer illnesses	0.7	1.2	5.5	-0.0	-1.7	-0.7	-0.7	-0.6	-0.5	-0.8	-0.2	-0.8	-0.3	-2.3	-1.7	-2.0	-0.7	-0.7	-0.4
Financial situation satisfaction	0.7	0.9	2.8	0.4	0.6	0.6	1.3	1.3	0.4	1.4	1.4	1.3	0.8	0.3	0.5	-0.5	-0.1	0.0	1.7
Supplements: Fish oil (including cod liver oil)	0.7	0.9	3.1	0.2	0.5	0.8	1.1	1.0	1.3	1.0	0.7	0.7	0.7	1.4	0.4	1.1	1.0	0.2	1.8
Alcohol drinker status: Previous	0.7	0.8	3.4	-1.3	-0.5	-1.0	-0.1	-0.0	-0.1	0.2	0.1	-0.1	-1.2	0.3	-1.9	0.6	1.1	-1.6	0.3
Alzheimer’s Disease (in mother)	0.6	0.7	1.6	-0.1	0.0	0.7	1.1	1.1	1.0	1.0	1.1	1.2	0.7	0.7	-0.1	-0.2	0.8	-0.3	1.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.5	-0.7	-1.2	-0.9	-0.6	-0.5	-1.3	-0.8	-0.5	-0.9	-1.0	-0.6	-0.5	-0.0	0.8	-1.6	-1.3
Current tobacco smoking	0.6	0.9	5.5	-1.0	-2.3	-0.5	-0.6	-0.6	0.7	-0.5	-0.7	-0.5	-1.2	-0.0	-0.4	1.4	1.1	-1.1	-0.4
Nervous feelings	0.6	1.1	2.5	0.9	0.1	1.3	1.1	0.7	1.1	0.7	0.8	0.9	1.6	0.8	0.6	-0.9	-1.2	1.4	1.3
Hair/balding pattern: Pattern 2	0.6	0.7	3.2	0.2	0.3	-0.0	-0.5	-0.6	-1.8	-0.8	-0.8	-0.6	-0.8	-0.5	0.7	-1.6	-1.1	-0.1	-1.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.4	-0.9	-1.1	-0.7	-1.2	-0.8	1.2	-0.6	-0.9	-0.9	-0.1	-0.3	-0.5	1.1	0.9	-0.6	-0.5
Mouth/teeth dental problems	0.6	1.0	4.5	-0.5	1.0	0.9	0.6	0.7	1.0	0.5	0.8	0.5	0.4	1.5	0.9	1.3	2.1	-0.3	0.9
Allergy	0.6	1.4	4.7	-0.8	1.8	-0.9	0.8	0.6	-2.1	1.0	0.7	1.1	-0.7	2.2	0.2	2.1	-0.0	-0.7	-0.2
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	3.8	1.5	0.1	0.8	0.3	0.5	0.3	0.3	0.5	0.2	1.4	0.3	1.9	0.5	-0.4	1.3	0.1
Alcohol intake versus 10 years previously	0.6	0.9	6.2	1.9	-0.5	-0.7	0.5	0.2	-0.7	0.4	0.3	0.6	0.2	0.2	-0.4	-1.0	-2.5	1.4	0.1
Father’s age at death	0.6	0.8	3.7	-1.2	-1.9	0.1	-0.7	-0.4	0.0	-0.5	-0.8	-0.4	-0.7	-1.3	-0.2	-1.8	0.6	-0.9	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.0	-1.1	-1.4	-0.2	-0.9	-0.9	0.1	-0.8	-0.7	-0.9	-0.9	-0.2	0.3	-0.1	1.3	-1.0	0.1
Impedance of arm (left)	0.6	2.9	9.1	-1.6	1.0	1.3	0.9	1.1	1.0	1.1	1.0	1.3	0.8	2.8	2.6	2.3	3.0	-1.2	1.6
Exposure to tobacco smoke outside home	0.6	0.8	4.3	1.5	-0.3	0.1	0.5	0.6	-0.5	0.8	0.7	0.7	0.2	0.4	0.3	-0.7	-2.1	1.1	1.1
Worry too long after embarrassment	0.6	0.9	1.8	1.2	0.5	0.6	0.9	0.7	1.1	0.6	1.1	0.7	1.4	0.9	1.0	1.4	-0.1	1.0	1.3
Migraine (self-reported)	0.6	0.8	1.7	-0.2	1.3	1.3	0.6	1.1	-0.8	1.1	1.1	1.1	0.1	0.6	0.9	-1.1	0.1	-0.5	1.0
Medication: Seretide 50 evohaler	0.6	0.7	2.7	0.7	-0.9	0.6	0.5	0.4	1.7	0.4	0.6	0.4	1.3	-0.0	0.2	0.7	-0.0	0.9	1.6
Suffer from ‘nerves’	0.6	0.9	3.1	-0.6	-0.8	-0.7	-0.5	-1.0	-1.1	-0.8	-0.9	-0.7	-0.7	-1.0	-1.3	-1.8	-1.2	-0.7	-1.1
Family relationship satisfaction	0.6	0.7	2.0	-0.5	1.3	-0.7	0.8	0.7	0.3	1.1	0.7	1.0	0.9	0.5	-1.4	1.2	-0.0	-0.5	0.6
Knee pain experienced in last month	0.6	0.9	2.5	1.2	-0.1	1.2	0.3	0.5	1.3	0.4	0.5	0.9	1.1	0.3	1.3	0.5	-1.4	1.6	0.6
Long-standing illness, disability or infirmity	0.6	0.9	6.2	-0.0	-2.5	-1.0	-0.5	-0.4	-0.3	-0.1	-0.3	-0.3	-0.8	-0.3	-1.1	-0.1	-1.8	-0.8	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.8	0.2	-1.5	-1.1	-1.0	-1.1	0.4	-0.9	-1.1	-1.0	-0.8	-1.7	-0.8	-0.2	-0.5	0.1	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	4.2	-0.9	-0.3	-2.0	-0.1	-0.3	-0.3	-0.3	-0.5	-0.4	-0.1	-0.4	-1.7	1.2	0.1	-0.8	-0.3
Mineral and other dietary supplements	0.6	0.8	2.5	0.3	-0.8	-0.8	-1.1	-1.0	-0.8	-1.0	-0.9	-0.7	-0.6	-1.2	0.1	-0.9	-1.1	0.0	-1.6
Breast cancer (self-reported)	0.6	0.7	3.6	0.4	0.8	0.2	0.9	0.8	0.2	0.7	0.8	0.6	1.0	0.7	0.9	1.9	0.9	0.5	0.3
Osteoporosis (self-reported)	0.6	0.7	2.4	0.6	0.9	1.5	0.7	0.7	0.1	0.5	0.9	0.3	0.1	1.1	1.5	0.2	-0.7	0.7	0.9
Osteoarthritis (self-reported)	0.6	0.7	3.9	0.1	-2.0	-0.6	-0.8	-0.7	-0.1	-0.7	-0.9	-1.0	-0.6	-0.9	-0.1	-0.7	-1.5	0.1	-0.4
Ever smoked	0.6	1.1	4.4	-0.8	-2.1	-1.2	-0.9	-0.9	0.1	-1.0	-1.1	-1.0	-1.1	-1.3	-1.4	0.5	0.0	-0.8	-0.8
Number of operations (self-reported)	0.6	0.9	4.0	0.0	-0.4	-2.0	-0.4	-0.4	-1.2	-0.6	-0.5	-0.7	-0.5	-1.4	-1.7	0.2	-0.5	-0.2	-1.3
Commuting to job workplace: Cycle	0.6	0.8	7.1	-1.4	-0.3	-0.2	0.1	0.2	-0.2	0.1	0.1	-0.3	-0.1	0.1	-0.8	0.2	2.7	-1.4	-0.5
Depression (Nagel 2018)	0.5	0.8	2.5	0.2	-0.1	0.0	1.3	1.3	0.3	1.0	1.4	1.3	0.9	-0.0	-0.7	0.6	0.5	-0.0	1.6
Alzheimer’s Disease (in father)	0.5	0.5	1.3	0.2	0.1	0.4	0.7	0.8	-0.3	0.9	0.7	0.8	0.8	1.1	0.4	1.1	-0.7	0.6	0.6
Irritable Bowel Disease (IBD)	0.5	1.3	2.5	-1.0	-0.9	-1.1	-1.2	-1.2	-0.5	-1.4	-1.1	-1.1	-0.9	-1.4	-1.6	-1.4	-0.3	-1.1	-0.9
Neuroticism (2016)	0.5	0.7	2.1	0.8	0.6	0.4	0.9	0.9	0.2	1.0	1.3	1.0	0.9	1.2	0.0	-0.3	-0.4	0.7	1.4
Systolic Blood Pressure	0.5	2.7	14.5	2.8	0.3	0.0	0.3	0.0	1.3	0.3	0.4	0.6	2.1	-1.3	-0.4	-0.9	-3.8	3.4	0.5
Vitamin and mineral supplements	0.5	0.7	1.5	1.0	-1.1	-0.4	-0.7	-0.9	-0.4	-0.9	-0.7	-0.7	-0.7	-1.2	0.2	-0.5	-1.1	0.9	-0.7
Severe depression (siblings)	0.5	0.6	1.2	0.4	0.7	0.6	1.1	0.9	-0.3	0.9	0.8	0.9	-0.0	1.0	0.7	0.7	-0.7	0.2	1.0
Age when periods started (menarche)	0.5	1.1	4.6	-1.1	0.3	1.0	0.6	0.8	0.3	0.8	0.7	0.2	-0.1	2.1	1.8	0.1	2.1	-1.1	0.1
Serious illness, injury or assault to yourself	0.5	0.6	2.3	-1.5	-0.3	-0.3	0.4	0.4	-1.0	0.7	0.5	0.4	-0.9	1.1	-0.0	0.1	0.5	-1.1	0.8
Hayfever, allergic rhinitis or eczema	0.5	1.1	5.4	0.9	-0.4	1.8	-0.3	0.1	2.3	-0.5	-0.2	-0.5	1.2	-0.8	1.3	-1.0	0.8	1.0	0.3
Medication: Atenolol	0.5	0.7	3.6	-0.5	-0.9	-0.6	-0.7	-0.6	-0.8	-0.3	-0.3	-0.3	-0.4	-0.9	-1.2	-1.9	-0.9	-0.4	-0.7
Sitting height	0.5	3.4	7.2	0.1	-2.1	-1.4	-2.0	-2.3	-0.4	-2.7	-2.5	-2.6	-2.2	-1.9	0.8	0.4	1.4	-0.1	-2.7
Number of incorrect matches in round	0.5	0.8	3.4	-0.5	0.3	1.8	0.8	1.0	1.0	1.3	0.8	1.1	0.2	1.2	0.5	-0.9	0.3	-0.4	0.4
Forced vital capacity (FVC)	0.5	1.8	5.8	-0.5	-1.3	-1.3	-1.3	-1.3	0.4	-1.5	-1.6	-1.5	-2.4	-0.5	-0.1	0.9	2.2	-0.7	-1.4
Heart attack	0.5	0.6	1.7	-0.4	0.9	0.3	0.7	0.9	0.7	0.9	0.9	1.0	0.9	-0.1	-1.3	-0.3	1.1	-0.4	0.3
Fluid intelligence score	0.5	1.1	2.1	0.6	0.3	1.5	1.3	1.4	1.4	1.1	1.1	1.1	0.4	1.0	1.2	0.5	1.4	0.4	1.3
Impedance of arm (right)	0.5	2.5	6.9	-1.4	1.0	1.2	0.9	1.1	0.8	1.1	0.9	1.4	1.1	2.6	2.6	2.1	2.4	-1.1	1.4
Hair/balding pattern: Pattern 3	0.5	0.7	1.7	0.6	-0.1	0.9	1.1	1.1	0.9	1.1	1.1	0.8	0.7	1.3	0.4	0.2	0.7	0.6	0.9
High blood pressure (siblings)	0.5	0.7	5.1	0.3	1.1	-0.3	0.5	0.4	-0.9	0.4	0.7	0.2	0.7	-0.6	-1.3	-0.2	-2.3	0.8	0.4
Neck or shoulder pain in last month	0.5	0.7	4.2	1.1	0.3	0.1	0.7	0.5	0.1	0.7	0.7	0.7	0.4	1.2	0.7	2.1	-0.4	1.1	-0.1
Medication: Ibuprofen	0.5	0.6	2.0	0.3	-1.1	0.4	-0.9	-0.7	0.8	-0.6	-0.9	-0.5	-0.7	-1.4	0.4	-0.7	-0.6	0.3	-0.8
Medication: Omeprazole	0.5	0.6	2.8	-0.8	-0.4	-1.0	-0.4	-0.3	-0.6	-0.0	-0.1	-0.2	0.7	-0.1	-1.5	-0.5	-1.7	-0.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	4.5	-0.2	-0.9	-0.7	-1.0	-1.0	0.2	-1.0	-1.1	-1.2	-1.6	-0.1	0.3	1.4	2.1	-0.7	-1.3
Average weekly red wine intake	0.5	0.7	2.8	-0.7	-0.1	-1.0	-0.0	-0.1	-1.5	-0.1	-0.3	-0.4	-1.1	0.8	0.0	1.7	1.0	-1.0	-0.4
Medication: Gliclazide	0.5	0.6	3.3	0.6	0.1	0.4	0.5	0.4	0.8	0.5	0.6	0.4	1.1	1.0	1.1	1.8	0.0	0.8	0.5
Smoking status: Current	0.5	0.8	5.6	-0.6	-2.4	-0.5	-0.6	-0.6	0.9	-0.6	-0.7	-0.5	-1.0	-0.1	-0.3	1.3	0.9	-0.7	-0.3
Age started oral contraceptive pill	0.5	0.6	6.5	1.0	0.2	0.3	-0.5	-0.4	0.2	-0.3	-0.2	-0.2	0.5	-0.1	0.3	-0.6	-2.5	0.8	-0.3
Vascular/heart problems diagnosed by doctor	0.5	1.5	8.8	-1.8	0.3	-0.3	-0.7	-0.6	0.0	-0.6	-0.9	-0.5	-1.3	1.2	1.3	1.6	3.0	-1.4	-0.4
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.6	-0.4	1.0	0.5	0.7	1.0	0.6	0.9	0.9	1.0	0.8	-0.1	-1.3	-0.6	1.0	-0.4	0.4
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.8	0.8	0.6	1.0	0.7	0.8	1.3	0.8	0.7	1.0	0.5	1.1	1.7	1.6	0.9	0.7	1.0
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.6	0.2	-0.4	-0.2	0.8	0.6	0.6	0.7	0.6	0.4	0.6	0.8	-1.2	1.0	-0.1	0.3	0.8
Smoking Status	0.4	1.0	6.1	-0.6	-2.5	-1.0	-0.6	-0.6	1.0	-0.6	-0.7	-0.6	-0.9	-0.2	-1.1	1.6	-0.3	-0.8	-0.2
Chronotype (morning person)	0.4	0.9	3.5	1.1	-0.7	-0.8	-1.0	-0.8	0.4	-1.4	-0.7	-0.9	0.4	-1.9	-0.6	-0.9	-0.2	0.9	-1.1
Sensitivity / hurt feelings	0.4	0.8	2.3	0.3	0.8	0.2	1.2	1.0	-0.5	0.9	1.4	1.3	0.7	0.9	0.5	0.4	-0.4	0.3	1.5
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.4	1.0	-0.0	0.3	1.0	0.9	0.6	0.7	1.2	0.8	0.6	-0.0	-0.5	0.3	0.1	0.7	1.0
Supplements: Zinc	0.4	0.4	1.0	-0.4	0.4	0.5	0.9	0.9	-0.3	1.0	0.6	0.9	0.3	1.0	0.4	-0.2	-0.0	-0.6	0.2
Hand grip strength (right)	0.4	1.2	2.8	0.2	-0.2	-1.3	-0.8	-1.1	0.1	-1.4	-1.5	-1.4	-1.7	-1.1	-1.7	0.8	0.2	-0.1	-1.3
Relative age voice broke	0.4	0.7	2.1	0.4	0.8	1.1	0.7	0.7	-0.5	0.8	1.2	1.0	-0.5	-0.0	-0.1	-1.5	-0.8	0.0	1.3
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.2	-0.8	0.3	-0.5	0.3	0.3	-1.5	0.4	0.5	0.4	0.3	0.7	0.2	0.9	-0.9	-1.1	0.1
High blood pressure (mother)	0.4	0.6	1.4	1.0	-0.2	-0.7	0.6	0.3	1.0	0.2	0.5	0.2	0.9	-0.8	-1.1	0.8	-0.9	0.8	1.2
Past tobacco smoking	0.4	0.7	3.0	0.5	1.7	1.1	0.7	0.7	-0.5	0.7	0.9	0.7	0.6	0.9	1.1	-0.8	0.4	0.5	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.4	1.0	0.6	0.4	0.4	0.3	1.1	0.4	0.4	0.3	1.2	0.6	1.0	1.1	1.1	1.0	0.2
Financial difficulties in last 2 years	0.4	0.6	2.7	0.3	-1.6	-0.5	-0.6	-0.6	-0.5	-0.7	-0.6	-0.4	-1.6	-0.9	0.3	0.1	0.1	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	5.3	0.2	-0.4	-0.6	-0.7	-0.6	0.9	-0.8	-1.0	-0.9	-1.5	1.2	1.7	2.3	1.6	-0.1	-0.9
Medication: Cholesterol lowering	0.4	0.6	1.6	-0.1	0.5	0.6	0.7	1.0	1.0	0.9	1.0	1.0	1.2	0.8	-0.3	0.5	1.1	0.1	0.6
Exposure to tobacco smoke at home	0.4	0.4	1.5	1.2	-0.5	-0.4	-0.2	-0.3	-0.4	-0.3	-0.2	-0.6	-0.4	-0.9	-0.5	-1.0	-1.2	0.8	0.2
Leg fat percentage (right)	0.4	1.4	7.4	-0.7	-0.2	-2.0	-0.6	-0.7	-1.6	-0.7	-0.4	-0.7	-0.1	-1.6	-2.7	-0.1	-1.1	-0.8	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.6	-1.1	0.5	-0.9	0.1	0.0	-0.2	-0.2	-0.1	-0.1	0.0	0.0	-1.3	1.1	1.0	-1.1	-0.9
Health satisfaction	0.4	0.5	1.3	0.7	0.3	0.2	1.1	0.8	0.9	0.9	0.8	0.9	0.4	0.2	-0.4	0.4	-0.1	0.6	1.0
Eye problems/disorders: None of the above	0.4	0.5	1.3	1.0	0.2	0.8	0.1	0.2	1.1	0.2	0.1	0.5	0.5	0.5	1.2	1.1	-0.1	0.9	0.6
Illnesses of father: None of the above (group 1)	0.4	0.5	3.9	0.1	-0.4	0.3	-0.4	-0.2	0.8	-0.3	-0.4	-0.6	-0.6	0.8	2.0	0.3	1.1	-0.1	-0.2
Eye problems/disorders: Glaucoma	0.4	0.5	1.5	-0.1	0.8	0.5	1.0	0.9	0.3	0.7	0.7	0.8	-0.5	0.1	-0.1	0.5	1.2	-0.2	0.9
High cholesterol (Self-reported)	0.4	0.7	2.6	-0.9	-1.6	-0.8	-0.7	-0.7	-0.3	-0.8	-0.7	-0.7	-0.8	-0.8	-1.1	0.0	0.2	-1.1	-0.6
Medication: Bendroflumethiazide	0.4	0.7	3.0	-0.1	-1.3	-0.5	-0.2	-0.3	0.1	-0.2	-0.1	-0.3	-0.0	-1.5	-1.7	-0.8	-1.5	-0.1	0.3
Medication: Paracetamol	0.4	0.6	3.4	0.9	-1.8	-0.2	-0.7	-0.6	-0.2	-0.8	-0.5	-0.5	-1.2	-0.7	0.0	-0.3	-0.3	0.1	-0.9
Pain experienced in last month	0.4	0.6	2.4	-0.9	0.6	-1.0	-0.4	-0.5	-0.2	-0.5	-0.5	-0.4	0.3	-0.9	-1.6	-1.5	-0.4	-0.5	0.1
Major Depression (MDD)	0.3	0.3	2.7	0.3	-0.9	0.3	-0.3	-0.1	1.6	-0.1	0.1	0.0	0.6	-0.4	0.5	-0.6	0.5	0.1	0.1
Blood Red Count	0.3	2.7	19.4	-4.4	1.1	-1.0	-0.0	0.2	-0.0	-0.2	0.1	-0.3	0.9	-0.2	-2.6	-0.2	1.9	-3.2	0.5
Number of treatments/medications taken	0.3	0.5	2.6	0.2	-1.1	-0.1	-0.7	-0.4	0.1	-0.6	-0.1	-0.6	0.2	-1.6	-1.1	-0.8	-0.6	0.3	-0.3
Average weekly spirits intake	0.3	0.3	1.4	0.3	-0.6	-0.2	-0.5	-0.2	-0.4	-0.5	0.0	-0.4	-0.4	-1.2	-1.0	-1.1	-0.1	-0.1	-0.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	2.1	0.1	0.3	-0.3	-0.2	-0.3	-0.0	-0.6	-0.3	-0.8	0.2	-0.9	-0.7	-1.4	-0.2	0.2	-0.7
Medication for hormone replacement therapy	0.3	0.3	1.8	-0.2	-0.8	-0.7	-0.1	-0.2	0.4	-0.3	-0.4	-0.5	-0.5	0.2	-0.2	1.4	1.1	-0.3	-0.0
Average weekly fortified wine intake	0.3	0.4	0.9	0.2	0.7	0.2	1.0	0.8	0.5	0.8	1.0	0.7	0.1	0.5	-0.5	0.3	0.8	-0.2	0.6
Multivitamins +/- minerals	0.3	0.4	0.8	-0.3	0.8	0.8	0.7	0.9	0.5	0.8	0.4	0.7	0.7	0.9	0.5	-0.2	0.8	-0.4	0.3
Supplements: Glucosamine	0.3	0.4	1.2	-0.8	0.8	0.2	0.7	0.5	-0.4	0.6	0.5	0.5	0.2	0.2	-1.1	0.4	-0.3	-0.5	1.0
Had menopause	0.3	0.3	2.5	-0.6	0.1	0.2	-0.4	-0.3	-0.4	-0.3	-0.5	-0.2	-0.6	-0.9	-0.0	-1.6	0.0	-0.5	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.8	0.3	-0.7	0.7	-0.6	-0.3	0.5	-0.3	-0.6	-0.2	-0.8	-0.9	0.9	-0.4	-0.2	0.2	-0.7
Lung cancer (father)	0.3	0.3	2.1	-0.3	-0.8	0.3	0.1	0.1	1.4	0.0	0.0	-0.3	0.3	0.8	0.4	0.9	0.7	-0.4	0.4
Pulse wave Arterial Stiffness index	0.3	0.3	1.6	-0.3	-0.9	-0.0	-0.7	-0.3	0.0	-0.2	-0.5	-0.5	0.8	-0.3	0.2	0.1	-1.3	0.0	-0.8
Standing height	0.3	2.8	14.1	-0.8	-1.0	-1.1	-1.3	-1.5	0.3	-1.9	-1.8	-1.9	-2.6	-0.5	0.6	1.5	3.8	-1.2	-1.6
Hair/balding pattern: Pattern 4	0.3	0.8	5.2	0.6	1.3	0.4	0.2	0.2	1.8	0.1	0.4	0.3	2.3	-0.1	0.0	0.3	-0.7	1.3	0.5
Forced vital capacity (FVC), Best measure	0.3	1.0	5.2	0.7	-0.4	0.2	-0.1	-0.0	2.1	-0.3	-0.4	-0.3	-0.8	0.5	1.2	1.6	2.3	0.7	0.3
Shortness of breath walking on level ground	0.3	0.3	3.8	0.5	0.0	0.0	-0.0	0.0	-0.2	0.2	0.1	0.4	0.3	0.0	-0.3	-0.6	-2.0	0.2	0.2
Mean time to correctly identify matches	0.3	0.5	3.0	0.6	0.0	0.3	-0.2	-0.1	1.7	-0.2	-0.1	-0.3	1.5	0.2	-0.0	0.2	-1.0	0.9	0.2
Comparative height size at age 10	0.3	1.8	4.1	0.7	-2.0	-1.2	-1.3	-1.4	0.6	-2.0	-1.6	-1.8	-1.7	-1.6	-0.0	0.8	1.0	0.3	-1.2
Overall health rating	0.3	0.6	2.6	1.2	-0.8	-0.3	0.7	0.5	0.2	0.6	0.6	0.5	0.9	-0.4	-0.5	-0.2	-1.6	1.0	-0.0
Leg pain on walking	0.3	0.3	1.3	0.8	-1.1	0.1	-0.1	-0.3	0.3	-0.0	-0.4	-0.0	-0.3	-0.1	-0.2	1.1	-1.0	0.7	-0.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.3	-1.1	1.1	-0.3	-0.4	-0.2	-0.7	-0.1	-0.3	-0.2	0.1	-0.5	-0.9	-0.4	0.2	-0.8	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	5.3	0.1	0.2	-0.3	0.4	0.5	0.1	0.6	0.3	0.4	-0.6	1.9	0.8	2.3	0.7	-0.1	0.3
Leg fat percentage (left)	0.3	0.9	7.6	-0.5	0.2	-1.7	-0.1	-0.2	-1.0	-0.3	0.1	-0.3	0.3	-1.4	-2.8	0.2	-0.6	-0.6	-0.6
Supplements: Calcium	0.3	0.3	2.6	-0.4	0.2	0.5	0.1	-0.0	-0.7	-0.1	0.0	0.1	-0.1	-0.6	-0.7	-1.6	0.2	-0.4	-0.3
Heart disease (siblings)	0.3	0.4	1.4	1.1	0.3	0.0	-0.2	-0.3	0.0	-0.3	-0.3	-0.3	0.1	-1.1	-0.1	-0.1	-1.0	0.8	-1.2
Pack years of smoking	0.3	0.4	1.8	0.7	0.6	-0.5	-0.3	-0.6	-0.4	-0.5	-0.2	-0.6	0.3	-0.7	-0.6	0.3	-1.3	0.8	-0.3
Schizophrenia (2018)	0.2	0.5	1.9	-0.6	-0.5	-0.8	-0.5	-0.4	0.7	-0.6	-0.2	-0.3	0.2	-1.0	-1.4	-0.1	1.3	-0.5	1.0
Reaction Time	0.2	0.4	2.1	1.0	-0.4	0.4	-0.2	-0.1	1.4	-0.2	-0.2	-0.2	0.6	0.1	-0.1	-0.2	-1.1	0.8	0.1
Breast Cancer	0.2	0.5	2.6	0.6	1.6	0.3	0.3	0.2	0.0	0.3	0.3	0.1	1.4	-0.1	0.2	-0.9	-1.2	0.7	-0.4
Bipolar Disorder (2011)	0.2	0.2	0.5	-0.4	0.2	0.3	0.2	0.4	0.2	0.4	0.4	0.3	0.4	0.7	0.5	0.4	0.7	-0.4	0.2
Fasting Glucose	0.2	0.2	0.7	0.1	0.5	-0.1	0.4	0.4	-0.6	0.5	0.6	0.5	0.8	-0.2	-0.5	-0.2	-0.4	0.2	0.6
HbA1C	0.2	0.2	1.0	-0.5	0.6	0.4	0.1	0.2	-0.3	0.5	0.3	0.2	0.3	0.8	0.7	-1.0	0.0	-0.2	-0.2
LDL Cholesterol	0.2	0.4	2.5	0.2	-1.0	0.1	-0.3	-0.3	-0.2	-0.3	-0.3	-0.2	-0.2	0.5	1.2	-0.4	-1.6	0.1	0.2
Lupus	0.2	0.2	0.7	0.6	-0.4	0.4	-0.0	0.1	0.7	-0.3	-0.3	-0.0	0.6	-0.7	0.8	-0.7	-0.1	0.8	0.0
Height	0.2	4.6	39.1	-0.0	0.3	0.8	0.6	0.8	3.3	0.0	0.0	-0.2	-1.1	1.2	2.0	3.9	6.2	-0.0	0.5
Waist Hip Ratio (WHR)	0.2	1.0	4.4	1.8	0.1	0.1	0.0	-0.2	1.2	0.1	0.1	0.3	1.2	-1.1	-1.1	0.6	-1.6	2.1	-0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.9	0.3	0.9	0.8	0.9	0.9	0.3	0.7	0.9	0.7	0.7	0.8	0.4	0.2	0.4	0.2	0.5
Lung FVC	0.2	1.2	3.7	1.9	0.9	0.8	0.6	0.7	1.9	0.7	0.6	0.8	0.8	0.2	0.8	1.6	0.0	1.9	0.5
Hair Pigment	0.2	4.7	7.7	-2.6	-2.3	-2.4	-2.5	-2.3	-2.0	-2.4	-2.5	-2.0	-2.2	-2.2	-1.8	-0.4	-0.5	-2.8	-2.4
Pack years adult smoking proportion	0.2	0.3	1.6	0.6	0.7	-0.4	-0.2	-0.5	-0.4	-0.4	-0.2	-0.5	0.3	-0.7	-0.6	0.1	-1.3	0.6	-0.3
Fed-up feelings	0.2	0.4	2.0	0.2	0.7	0.3	0.8	0.8	-0.5	0.7	0.7	1.0	-0.0	0.8	-0.1	1.4	0.3	-0.1	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.4	0.1	-0.7	-0.1	0.3	0.4	0.4	0.2	0.4	0.4	-0.3	-0.2	-0.1	0.7	1.2	-0.2	0.9
Taking other prescription medications	0.2	0.4	1.5	-0.8	-0.5	-0.5	0.0	0.3	-1.2	0.3	0.5	0.2	0.5	-0.5	-1.1	0.0	-0.7	-0.7	-0.1
Qualifications: None of the above	0.2	0.4	2.4	0.0	-0.2	0.4	0.3	0.5	0.7	0.5	0.4	0.7	0.7	-0.8	-1.6	0.1	0.9	-0.1	0.2
Falls in the last year	0.2	0.3	2.0	0.3	-0.8	0.4	0.2	0.5	-0.3	0.5	0.5	0.5	-0.0	0.8	1.4	0.2	-0.4	0.1	0.6
Happiness	0.2	0.2	1.6	0.2	-0.0	-0.9	0.3	0.0	0.2	0.2	-0.0	0.1	0.4	-0.3	-1.3	0.4	-0.5	-0.2	-0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.4	-0.8	-0.0	-0.2	0.2	0.1	-0.6	0.1	0.1	-0.0	-0.8	1.2	0.6	1.2	0.5	-0.9	0.3
Mouth/teeth dental problems: Dentures	0.2	0.4	2.2	-0.5	-0.1	-0.3	0.6	0.8	-0.5	0.6	0.6	0.8	0.3	-0.2	-1.5	0.5	0.5	-0.2	0.4
Pulse wave reflection index	0.2	0.2	1.3	0.4	0.3	0.3	-0.1	0.1	-0.0	0.1	0.3	0.2	0.6	-0.4	0.3	-1.2	-0.5	0.5	0.6
Medication: Paracetamol	0.2	0.4	1.5	1.2	-0.8	0.2	0.3	0.4	0.0	0.4	0.6	0.5	-1.0	0.4	0.4	1.0	0.6	0.4	-0.0
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.1	0.3	-0.1	-0.3	-0.2	-0.5	0.4	-0.2	-0.5	-0.7	-0.0	0.2	-0.1	1.1	-0.8	0.8	-0.7
Comparative body size at age 10	0.2	0.5	2.0	0.2	-0.0	-1.4	0.2	0.3	-0.3	0.2	0.4	0.5	-0.5	-0.5	-1.4	1.4	-0.4	-0.2	0.7
Wheeze or whistling in the chest in last year	0.2	0.3	2.1	-0.1	-0.4	0.4	-0.1	-0.1	0.4	-0.2	0.2	-0.1	0.4	-1.5	-1.4	-0.4	0.2	0.4	0.3
Age at first live birth	0.2	0.4	2.8	-0.3	0.7	0.1	-0.4	-0.4	-1.0	-0.6	-0.4	-0.5	-0.0	-0.2	0.9	-1.7	-0.2	0.1	-0.2
Pulse wave peak to peak time	0.2	0.3	1.9	0.2	0.7	-0.1	0.6	0.1	-0.0	0.0	0.3	0.3	-1.1	0.2	-0.3	0.1	1.4	-0.2	0.6
Chest pain or discomfort	0.2	0.3	2.2	-0.6	-0.0	-0.8	-0.1	-0.0	-1.5	-0.2	0.1	-0.3	0.0	-0.3	-0.4	-0.4	0.9	-0.8	-0.5
Age at last live birth	0.2	0.3	2.5	-0.2	0.5	0.5	-0.1	-0.1	-0.6	-0.1	-0.0	-0.0	0.1	0.2	0.7	-1.6	-0.3	0.4	0.4
Back pain experienced in last month	0.2	0.3	3.2	0.5	-0.5	0.2	0.0	0.1	-0.2	0.1	0.0	-0.1	-0.5	0.3	0.7	1.8	0.4	0.4	-0.3
Ever taken oral contraceptive pill	0.2	0.2	1.8	0.2	0.3	-0.4	-0.2	-0.2	-0.4	-0.2	-0.3	-0.2	0.8	0.0	-0.3	0.0	-1.4	0.4	0.0
Mother’s age at death	0.2	0.2	0.7	-0.1	-0.8	0.3	-0.0	-0.2	0.5	-0.5	-0.4	-0.4	-0.1	-0.3	0.3	-0.8	-0.4	-0.2	0.6
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.2	-0.5	0.5	0.2	0.4	0.4	0.5	0.3	0.3	0.1	-0.1	-0.1	-1.1	-0.6	0.8	-0.5	0.4
Risk taking	0.2	0.3	1.2	0.3	-0.2	-0.3	0.5	0.3	0.6	0.3	0.3	0.4	0.6	-0.5	-0.9	1.1	0.5	0.0	-0.1
Diastolic blood pressure, automated reading	0.2	0.5	2.2	0.8	0.2	-0.7	-0.2	-0.4	0.6	-0.4	-0.6	-0.6	1.3	-0.3	-0.4	0.7	-1.5	1.0	-0.5
Ever depressed for a whole week	0.2	0.2	2.1	-0.2	-0.6	-0.0	-0.3	-0.2	1.4	0.1	-0.3	-0.2	0.8	-0.3	-0.1	-0.2	0.0	0.0	-0.2
Unable to work because of sickness or disability	0.2	0.2	1.5	-0.2	-0.9	-0.6	-0.2	-0.1	0.3	0.1	-0.1	-0.3	0.2	0.1	-0.7	1.2	0.4	-0.1	-0.0
Bipolar Disorder (2018)	0.1	0.2	0.8	-0.2	0.4	0.4	0.4	0.7	-0.7	0.4	0.4	0.7	0.2	-0.1	0.2	-0.9	0.2	-0.3	0.5
Bipolar Disorder or Schizophrenia	0.1	0.3	1.2	-0.5	-0.1	-0.5	0.1	0.1	0.1	-0.2	0.1	0.2	0.3	-0.8	-1.1	-0.6	1.1	-0.5	1.1
Ulcerative Colitis (UC)	0.1	0.3	0.8	-0.5	-0.6	-0.4	-0.4	-0.4	-0.1	-0.5	-0.5	-0.5	-0.6	-0.3	-0.9	-0.5	-0.5	-0.6	-0.0
Ulcerative Colitis	0.1	0.1	1.0	0.3	-0.5	-0.3	-0.2	-0.2	-0.3	-0.3	-0.2	-0.1	-0.3	0.2	0.1	-0.3	-1.0	0.4	0.1
Hand grip strength (left)	0.1	0.3	1.5	0.6	0.1	-0.5	-0.2	-0.3	-0.0	-0.7	-0.7	-0.5	-1.2	-0.8	-0.6	0.0	-0.0	0.3	-0.6
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.7	-0.6	-0.2	0.9	0.3	0.2	-0.2	0.2	-0.0	0.2	-0.4	-0.2	0.3	-0.4	0.8	-0.4	-0.1
Townsend deprivation index at recruitment	0.1	0.1	1.2	0.3	-0.6	0.1	0.0	0.1	-0.5	0.3	0.2	0.2	-0.3	0.3	0.2	-0.3	-1.1	0.1	-0.1
Depression (self-reported)	0.1	0.1	0.4	-0.3	0.1	-0.3	-0.2	-0.1	-0.4	-0.1	0.1	-0.0	0.1	0.0	-0.0	-0.3	-0.6	-0.0	-0.7
Breastfed as a baby	0.1	0.2	0.9	-0.0	0.6	0.2	0.3	0.2	-0.8	-0.0	-0.0	0.0	-0.1	0.2	1.0	0.1	-0.2	-0.3	-0.4
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.7	0.0	-0.0	-0.4	-0.2	-0.0	-0.2	0.3	-0.1	0.4	0.1	0.7	0.5	0.8	-0.9	-0.3	-0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	1.0	0.2	-0.3	0.6	0.4	0.2	-0.4	0.0	0.0	-0.0	-0.2	-0.5	-0.0	-1.0	0.0	0.1	-0.1
Illnesses of father: Heart disease	0.1	0.2	1.0	0.1	-0.6	-0.1	0.2	-0.2	0.3	-0.1	-0.2	-0.4	0.1	-0.4	-1.0	0.3	-0.9	0.1	0.2
Smoking status: Previous	0.1	0.2	0.6	-0.1	-0.6	-0.7	-0.5	-0.4	0.4	-0.3	-0.5	-0.5	0.0	-0.5	-0.4	0.5	-0.8	-0.3	-0.3
Guilty feelings	0.1	0.2	0.6	-0.1	0.1	-0.1	0.3	0.6	-0.2	0.4	0.5	0.5	-0.0	0.6	0.4	0.8	0.7	-0.4	0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.5	0.1	-0.2	0.1	0.7	0.3	0.0	0.5	0.3	0.3	-0.2	0.3	0.1	0.1	-0.5	0.2	0.2
Tanning	0.0	0.5	3.8	-0.4	-0.5	-0.5	-0.1	-0.1	-0.4	-0.0	0.2	-0.1	-1.1	-0.9	-2.0	-0.6	-0.3	-0.6	0.4

Hub : Genes

RPN1

Models

Trait associations