Best TWAS P=5.6e-09 · Best GWAS P=2.05e-08 conditioned to 0.28
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | SLC35G2 | 0.16 | 0.03 | lasso | 8 | 0.05 | 6.4e-03 | -5.3 | 5.8 | 5.6e-09 | -0.87 | 0.07 | 0.69 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | RP11-85F14.5 | 0.10 | 0.08 | enet | 38 | 0.09 | 3.9e-07 | 2.9 | -5.1 | 2.8e-07 | 0.61 | 0.88 | 0.10 | FALSE |
| 3 | GTEx | Thyroid | RP11-85F14.5 | 0.07 | 0.00 | lasso | 7 | 0.01 | 4.7e-02 | 3.9 | -5.8 | 8.0e-09 | 0.57 | 0.10 | 0.28 | FALSE |