TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (left)
:
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chr4:55,598,706-57,110,821
Best TWAS P=3.08e-09 · Best GWAS P=3.22e-07 conditioned to 0.0996
55.6M
55.8M
56M
56.2M
56.4M
56.6M
56.8M
57M
57.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
CLOCK
0.19
0.09
lasso
6
0.11
2.0e-08
-3.4
5.9
3.1e-09
0.65
0.27
0.64
TRUE
2
GTEx
Thyroid
CLOCK
0.16
0.14
enet
46
0.14
9.5e-11
5.1
5.3
9.2e-08
0.82
0.01
0.98
FALSE
3
The Cancer Genome Atlas
Stomach Adenocarcinoma
CLOCK
0.08
0.07
enet
9
0.06
4.5e-05
5.1
5.3
1.0e-07
0.99
0.01
0.97
FALSE