Best TWAS P=3.08e-09 · Best GWAS P=3.22e-07 conditioned to 0.0996
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | CLOCK | 0.19 | 0.09 | lasso | 6 | 0.11 | 2.0e-08 | -3.4 | 5.9 | 3.1e-09 | 0.65 | 0.27 | 0.64 | TRUE |
2 | GTEx | Thyroid | CLOCK | 0.16 | 0.14 | enet | 46 | 0.14 | 9.5e-11 | 5.1 | 5.3 | 9.2e-08 | 0.82 | 0.01 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CLOCK | 0.08 | 0.07 | enet | 9 | 0.06 | 4.5e-05 | 5.1 | 5.3 | 1.0e-07 | 0.99 | 0.01 | 0.97 | FALSE |