TWAS
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Traits
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Impedance of leg (left)
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chr5:136,723,696-138,110,702
Best TWAS P=5.25e-11 · Best GWAS P=5.72e-13 conditioned to 0.000556
136.8M
137M
137.2M
137.4M
137.6M
137.8M
138M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
WNT8A
0.05
0.01
blup
300
0.03
1e-04
2
6.6
5.2e-11
-0.75
0.08
0.88
TRUE