[Hub]/) : Traits : Impedance of leg (left) : ← →

chr6:44,079,216-46,043,561

Best TWAS P=9.67e-16 · Best GWAS P=7.76e-16 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Brain Cortex	SUPT3H	0.28	0.01	lasso	7	0.01	2.1e-01	8.0	8.0	9.7e-16	0.98	0.03	0.89	TRUE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SUPT3H	0.06	0.05	lasso	3	0.05	3.9e-06	7.9	7.8	4.5e-15	0.99	0.02	0.98	FALSE
2	GTEx	Brain Cerebellar Hemisphere	SUPT3H	0.38	0.40	lasso	2	0.34	1.3e-09	7.4	7.4	9.7e-14	0.84	0.09	0.90	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	SUPT3H	0.16	0.11	lasso	4	0.08	3.6e-03	7.2	7.4	1.9e-13	0.94	0.04	0.82	FALSE
5	GTEx	Brain Hypothalamus	SUPT3H	0.33	0.03	lasso	8	0.03	5.9e-02	7.2	7.1	1.3e-12	0.79	0.05	0.66	FALSE
1	GTEx	Brain Caudate basal ganglia	SUPT3H	0.22	0.12	lasso	6	0.10	8.1e-04	7.4	7.1	1.5e-12	0.87	0.05	0.83	FALSE
16	The Cancer Genome Atlas	Stomach Adenocarcinoma	SUPT3H	0.05	0.01	blup	191	0.00	1.4e-01	7.4	6.9	4.3e-12	0.93	0.04	0.70	FALSE
9	GTEx	Testis	SUPT3H	0.30	0.16	lasso	7	0.17	6.7e-08	7.2	6.6	4.1e-11	0.93	0.02	0.98	FALSE
10	NTR	Blood	SUPT3H	0.03	0.02	lasso	7	0.02	1.9e-07	7.0	6.5	8.2e-11	0.70	0.82	0.18	FALSE
12	YFS	Blood	SUPT3H	0.06	0.09	lasso	13	0.12	2.2e-36	-4.2	6.4	1.3e-10	0.77	0.97	0.03	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	SUPT3H	0.07	0.05	enet	12	0.08	1.1e-09	7.2	6.4	1.9e-10	0.83	0.26	0.74	FALSE
7	GTEx	Cells Transformed fibroblasts	SUPT3H	0.15	0.10	lasso	4	0.13	8.8e-10	-3.3	6.2	4.9e-10	0.70	0.86	0.14	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SUPT3H	0.04	0.01	blup	191	0.02	6.5e-03	7.9	6.2	4.9e-10	0.85	0.09	0.87	FALSE
8	GTEx	Pituitary	SUPT3H	0.26	0.08	lasso	6	0.05	1.8e-02	6.6	6.2	5.0e-10	0.80	0.06	0.45	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	SUPT3H	0.15	0.13	blup	643	0.17	3.4e-21	7.3	5.7	1.4e-08	0.82	0.08	0.92	FALSE
4	GTEx	Brain Frontal Cortex BA9	SUPT3H	0.37	0.14	lasso	11	0.18	1.3e-05	7.4	5.2	1.8e-07	0.77	0.08	0.86	FALSE