[Hub]/) : Traits : Impedance of leg (left) : ← →

chr6:129,638,583-131,163,098

Best TWAS P=5.1e-12 · Best GWAS P=2.13e-10 conditioned to 0.604

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	L3MBTL3	0.20	0.08	lasso	4	0.09	1.1e-07	-4.8	-5.9	4.5e-09	0.89	0.11	0.89	FALSE
2	GTEx	Adipose Visceral Omentum	L3MBTL3	0.14	0.12	lasso	2	0.15	2.8e-08	-4.8	-5.7	1.0e-08	0.90	0.03	0.97	FALSE
3	GTEx	Breast Mammary Tissue	L3MBTL3	0.31	0.25	lasso	7	0.23	2.8e-12	-4.8	-5.4	5.4e-08	0.89	0.04	0.96	FALSE
4	GTEx	Breast Mammary Tissue	RP11-73O6.3	0.27	0.22	lasso	9	0.22	1.5e-11	-4.8	-5.2	2.0e-07	0.85	0.18	0.82	FALSE
5	GTEx	Breast Mammary Tissue (Male)	L3MBTL3	0.31	0.24	lasso	6	0.23	5.5e-06	-4.8	-5.5	3.0e-08	0.91	0.03	0.90	FALSE
6	GTEx	Breast Mammary Tissue (Female)	L3MBTL3	0.30	0.13	lasso	5	0.14	4.5e-05	-3.2	-5.2	1.7e-07	0.86	0.02	0.95	FALSE
7	GTEx	Breast Mammary Tissue (Female)	RP11-73O6.3	0.29	0.08	lasso	5	0.10	5.7e-04	-4.8	-5.4	5.5e-08	0.85	0.03	0.92	FALSE
8	GTEx	Colon Transverse	L3MBTL3	0.27	0.13	lasso	8	0.20	8.0e-10	-4.8	-5.7	9.2e-09	0.87	0.02	0.98	FALSE
9	GTEx	Colon Transverse	RP11-73O6.3	0.19	0.09	lasso	2	0.06	1.2e-03	-4.8	-5.2	2.0e-07	0.88	0.02	0.96	FALSE
10	GTEx	Esophagus Mucosa	L3MBTL3	0.26	0.18	lasso	2	0.23	2.7e-15	-4.8	-5.2	2.5e-07	0.82	0.90	0.10	FALSE
11	GTEx	Lung	L3MBTL3	0.37	0.34	lasso	4	0.38	4.1e-30	-4.8	-5.7	1.6e-08	0.89	0.41	0.58	FALSE
12	GTEx	Lung	RP11-73O6.3	0.15	0.08	lasso	5	0.12	2.2e-09	-4.8	-5.8	5.7e-09	0.91	0.02	0.98	FALSE
13	GTEx	Nerve Tibial	L3MBTL3	0.30	0.23	lasso	4	0.22	2.3e-15	-4.8	-5.3	1.2e-07	0.87	0.88	0.12	FALSE
14	GTEx	Pancreas	L3MBTL3	0.32	0.17	lasso	4	0.23	4.4e-10	-4.8	-5.5	4.9e-08	0.88	0.10	0.90	FALSE
15	GTEx	Prostate	L3MBTL3	0.35	0.27	lasso	5	0.17	5.9e-05	-4.8	-5.2	2.3e-07	0.87	0.03	0.90	FALSE
16	GTEx	Skin Sun Exposed Lower leg	L3MBTL3	0.25	0.25	lasso	9	0.24	1.4e-19	-4.8	-5.3	1.2e-07	0.86	0.73	0.27	FALSE
17	GTEx	Small Intestine Terminal Ileum	L3MBTL3	0.37	0.20	lasso	4	0.17	1.3e-04	-4.8	-5.2	1.7e-07	0.86	0.02	0.86	FALSE
18	GTEx	Spleen	L3MBTL3	0.64	0.34	enet	14	0.48	6.4e-14	-4.8	-5.9	4.5e-09	0.88	0.05	0.95	FALSE
19	GTEx	Stomach	RP11-73O6.3	0.21	0.12	lasso	6	0.06	5.9e-04	-6.3	-6.9	5.1e-12	0.89	0.01	0.96	TRUE
20	GTEx	Thyroid	L3MBTL3	0.40	0.39	enet	9	0.43	2.8e-35	-4.8	-5.7	9.7e-09	0.90	0.88	0.12	FALSE
21	GTEx	Thyroid	RP11-73O6.3	0.18	0.15	lasso	3	0.20	2.3e-15	-6.1	-5.9	4.1e-09	0.91	0.02	0.98	FALSE
22	GTEx	Whole Blood	L3MBTL3	0.22	0.20	lasso	9	0.20	5.1e-18	-4.8	-5.2	2.3e-07	0.86	0.85	0.15	FALSE