Best TWAS P=1.33e-08 · Best GWAS P=2.59e-13 conditioned to 6.24e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | MATN2 | 0.21 | 0.13 | lasso | 4 | 0.15 | 1.2e-12 | 4.7 | -5.7 | 1.3e-08 | 0.43 | 1 | 0 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | MATN2 | 0.19 | 0.11 | bslmm | 568 | 0.13 | 2.5e-16 | 4.7 | 5.3 | 1.2e-07 | -0.43 | 1 | 0 | FALSE |