TWAS
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Traits
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Traits
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Impedance of arm (right)
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chr8:98,182,843-99,748,557
Best TWAS P=1.33e-08 · Best GWAS P=2.59e-13 conditioned to 6.24e-08
98.2M
98.4M
98.6M
98.8M
99M
99.2M
99.4M
99.6M
99.8M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Sun Exposed Lower leg
MATN2
0.21
0.13
lasso
4
0.15
1.2e-12
4.7
-5.7
1.3e-08
0.43
1
0
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
MATN2
0.19
0.11
bslmm
568
0.13
2.5e-16
4.7
5.3
1.2e-07
-0.43
1
0
FALSE