Hub : Genes

MATN2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.150	0.0450	1.1e-04	0.053	0.019	0.047	0.028	0.050	4.9e-07	1.9e-03	1.9e-06	1.9e-04	1.0e-06
2	GTEx	Cells Transformed fibroblasts	0.088	0.0340	5.6e-03	0.031	NA	0.036	NA	0.044	2.1e-03	NA	9.8e-04	NA	3.1e-04
3	GTEx	Esophagus Muscularis	0.158	0.0610	4.4e-03	0.000	NA	-0.001	NA	0.000	3.0e-01	NA	4.0e-01	NA	3.4e-01
4	GTEx	Skin Not Sun Exposed Suprapubic	0.413	0.0700	3.1e-07	0.186	NA	0.132	NA	0.159	1.8e-10	NA	1.0e-07	NA	4.5e-09
5	GTEx	Skin Sun Exposed Lower leg	0.208	0.0550	7.9e-05	0.132	NA	0.151	NA	0.153	5.1e-11	NA	1.7e-12	NA	1.2e-12
6	ROSMAP	Brain Pre-frontal Cortex	0.186	0.0387	1.8e-07	0.109	0.101	0.123	0.130	0.123	6.4e-14	6.7e-13	1.5e-15	2.5e-16	1.7e-15
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.115	0.0370	1.5e-04	0.016	0.026	0.019	NA	0.025	5.3e-03	5.3e-04	2.7e-03	NA	7.6e-04
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.254	0.0970	1.4e-03	0.096	0.033	0.068	NA	0.084	3.7e-06	5.6e-03	9.9e-05	NA	1.5e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	0.9	2.9	0.9	0.5	-0.4	-1.7	-1.3	1.2	-0.1	-0.1
Bipolar Disorder or Schizophrenia	0.2	0.6	1.8	0.9	-0.0	-0.1	-1.3	-1.1	0.9	0.2	0.4
Depressed Affect (Nagel 2018)	0.9	1.8	3.5	-1.8	0.6	0.1	1.4	1.9	-1.5	-1.8	-0.2
Depression (Nagel 2018)	0.3	0.4	1.9	0.1	1.4	0.9	-0.4	-0.1	0.4	-0.2	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	0.4	0.7	0.4	-0.5	-0.4	-0.8	0.5	0.4
Neuroticism (Nagel 2018)	0.7	1.7	5.2	-1.3	0.4	-1.2	1.1	1.7	-1.2	-2.3	-0.3
Schizophrenia (2018)	0.1	0.1	0.3	0.4	-0.5	0.2	-0.3	-0.4	0.2	0.3	0.5
Schizophrenia vs Biploar Disorder	2.5	3.3	7.1	-1.8	-1.5	2.7	2.2	2.1	-2.1	-0.6	-0.2
Worry (Nagel 2018)	0.4	0.7	1.9	-0.7	0.5	-1.4	0.7	0.5	-0.1	-1.2	1.0
Alzheimer’s Disease (in mother)	0.7	0.8	2.3	0.6	1.1	1.4	-0.4	-0.7	-0.0	-0.4	-1.5
Alzheimer’s Disease (in father)	0.2	0.2	1.4	0.2	-0.1	0.4	0.2	-0.3	-0.2	0.0	1.2
Alzheimer’s Disease (including proxy)	0.5	0.8	4.2	0.1	1.0	2.0	0.1	-0.2	-0.5	0.1	-0.8
Crohns Disease (2017)	0.3	0.8	2.5	0.3	-0.4	1.6	0.4	0.0	0.0	1.5	0.9
Irritable Bowel Disease (IBD)	0.5	1.1	3.9	0.8	-0.1	0.8	-0.7	-1.0	0.6	2.0	1.3
Ulcerative Colitis (UC)	0.2	0.4	1.0	0.1	-0.7	-0.5	-0.7	-0.7	0.6	1.0	0.6
Major Depression (MDD)	0.1	0.1	0.2	0.1	-0.3	0.2	0.1	0.4	0.4	0.4	0.4
Reaction Time	0.2	0.4	1.2	-0.5	-0.9	0.6	0.5	0.2	-0.3	-0.4	-1.1
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.3	0.0	-0.1	-0.2	-0.0	0.3	-1.2	-1.0	0.1
Breast Cancer	0.1	0.2	0.6	0.6	0.7	-0.3	-0.4	-0.2	0.0	0.5	-0.1
Ovarian Cancer	0.5	0.6	1.3	-0.1	1.1	0.7	-0.8	-0.8	-1.1	-0.0	-0.6
Prostate Cancer	1.0	1.5	4.4	-0.7	-0.5	-0.2	0.8	0.9	-0.9	-2.1	-2.0
Age at First Birth	0.1	0.2	0.4	0.3	0.6	0.4	0.2	0.4	-0.3	0.4	0.5
Bipolar Disorder (2011)	0.2	0.2	1.0	0.2	-0.5	-1.0	-0.2	0.0	0.3	-0.3	0.0
Body Mass Index (BMI) (2010)	0.7	1.0	2.3	1.2	-0.9	-1.5	-0.4	-0.3	1.1	0.7	1.2
Coronary Artery Disease (CAD)	0.4	0.5	2.1	-0.2	-1.4	-0.0	-0.1	0.1	0.9	1.0	0.0
Crohns Disease (2012)	0.5	0.8	2.6	0.2	-0.7	1.6	0.3	0.3	0.6	1.2	1.1
Mean Putamen Volume	0.9	1.0	2.3	0.8	0.7	0.5	-1.0	-1.3	1.3	0.2	1.5
Fasting Glucose	0.3	0.3	0.7	0.2	0.6	0.7	-0.8	-0.2	0.1	0.8	0.6
HbA1C	0.2	0.2	0.8	0.0	-0.3	-0.2	-0.3	-0.7	0.2	0.7	0.9
HDL Cholesterol	0.4	0.6	1.9	-0.0	0.8	1.4	-0.6	-0.4	-0.0	1.1	-0.7
LDL Cholesterol	0.2	0.3	0.5	0.6	0.7	0.5	-0.6	-0.3	-0.3	-0.1	0.7
Lupus	3.3	5.0	10.4	-1.5	-0.1	-0.3	2.5	2.5	-2.1	-3.2	-3.2
Neuroticism (2016)	3.0	4.3	8.4	-2.5	-2.5	-1.2	2.4	2.9	-0.3	-2.4	-0.9
Primary Biliary Cirrhosis	0.5	0.7	2.2	0.6	0.0	-1.0	-1.0	-0.5	0.5	-0.7	-1.5
Rheumatoid Arthritis	0.9	1.2	2.3	1.0	0.7	-0.9	-1.5	-1.4	1.4	-0.5	-1.0
Schizophrenia (2014)	0.2	0.4	1.9	-0.6	-0.7	1.4	0.3	0.4	-0.4	0.6	0.1
Triglycerides	0.9	1.5	3.1	1.7	-0.2	-0.0	-0.7	-1.0	1.5	1.6	1.8
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.9	0.2	-0.9	0.3	0.2	-0.5	0.9	1.5	1.7
Ulcerative Colitis	0.3	0.4	1.4	-0.2	-1.0	-0.5	0.2	-0.1	0.4	0.5	1.2
Blood Eosinophil Count	0.2	1.6	2.6	-1.1	-0.7	1.3	1.6	1.5	-0.7	-1.2	-1.6
Blood Platelet Count	0.1	1.7	6.1	-1.0	0.8	0.2	1.4	0.9	-2.5	-1.4	-0.9
Blood Red Count	0.1	1.0	3.5	-1.9	-0.3	1.2	0.9	0.7	-1.0	-0.0	-0.8
Blood White Count	0.4	2.6	11.6	-1.6	-0.4	3.4	1.7	1.1	-1.4	0.6	-0.1
Heel T-Score	0.3	2.5	6.8	1.6	-0.1	-0.7	-1.3	-1.6	2.6	0.8	2.2
BMI	0.5	2.6	6.7	-1.5	-0.4	0.4	1.8	2.6	-2.4	-1.6	-0.4
Height	0.4	7.8	14.6	3.7	1.6	-2.9	-3.8	-3.5	3.1	0.7	-0.7
Waist Hip Ratio (WHR)	0.6	2.9	10.6	1.1	-3.3	-0.0	-0.7	-2.1	2.2	0.9	0.7
Systolic Blood Pressure	0.2	1.2	5.9	-0.4	-1.5	-2.4	0.3	-0.3	0.1	1.0	0.6
Smoking Status	1.1	2.5	5.9	-1.0	-2.3	2.4	1.7	1.9	-1.2	-0.6	-0.1
Allergy or Eczema	0.3	0.7	3.5	0.6	0.9	-0.6	-0.3	0.1	0.6	0.4	1.9
Cardiovascular Disease	0.1	0.4	1.5	-0.6	-0.6	0.4	0.4	0.2	-0.4	0.7	1.2
Hypothyroidism (self reported)	0.3	0.8	2.6	-0.5	0.7	-1.6	0.1	0.5	-0.1	-0.6	-1.6
Respiratory disease	2.1	4.6	8.4	2.2	1.3	2.9	-1.7	-1.1	2.2	2.8	2.4
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.8	0.7	1.0	-1.3	-0.1	-0.2	0.9	-0.4	0.3
Lung FEV1/FVC ratio	0.2	0.8	1.6	1.0	-0.5	-1.2	0.5	0.2	1.0	-1.3	-1.0
Lung FVC	0.6	3.0	11.0	-1.7	-2.2	3.3	1.5	1.1	-0.5	1.0	0.7
Neuroticism	0.2	0.4	1.3	-0.8	0.1	-0.2	0.4	0.7	-0.5	-1.2	0.1
Chronotype (morning person)	0.7	1.5	3.5	0.5	-0.6	1.5	-0.8	-1.0	1.8	1.9	0.9
Hair Pigment	0.1	1.6	3.1	-1.3	-1.7	1.2	1.6	1.8	-0.7	-0.7	-0.4
Tanning	0.1	1.2	5.1	1.4	2.3	-0.3	-1.2	-1.1	0.2	0.2	-0.3
Hand grip strength (left)	0.1	0.3	0.9	0.2	-0.5	-0.9	-0.8	-0.2	0.6	0.4	-0.2
Number of treatments/medications taken	0.2	0.4	1.4	0.5	0.7	-1.0	0.1	0.1	0.3	0.1	1.2
Average weekly spirits intake	0.6	0.7	2.0	-0.4	-1.2	-1.4	1.0	0.5	0.3	-0.2	1.0
Sensitivity / hurt feelings	0.2	0.3	0.9	-0.4	0.5	-0.4	0.1	0.1	-0.3	-0.8	-0.9
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.9	0.4	0.6	0.4	-0.7	-0.1	1.0	0.4	0.2
Hearing difficulty/problems: Yes	0.6	1.0	2.2	-0.6	-1.5	-0.6	-0.5	-0.7	1.2	0.7	1.5
Relative age of first facial hair	0.4	0.8	1.8	1.3	0.8	-0.4	-1.3	-0.8	1.3	-0.1	-0.5
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.9	-1.4	-0.9	0.3	1.1	1.1	-0.7	0.4	-0.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.5	0.3	-0.2	-0.6	0.6	0.6	0.7	-0.6	0.3
Ever had hysterectomy (womb removed)	0.4	0.5	1.6	1.0	0.4	0.1	0.5	-0.1	1.2	-0.8	-0.1
Systolic blood pressure, automated reading	0.4	1.2	5.9	-0.6	-1.2	-2.4	0.7	0.6	0.3	0.1	0.9
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	4.6	-1.9	-1.0	-0.2	1.4	1.4	-2.1	0.5	-0.9
Angina	0.4	0.6	2.3	-0.5	-1.2	-1.5	0.4	-0.2	-0.6	-0.3	0.2
Medication for hormone replacement therapy	1.4	1.5	3.8	-1.5	-0.5	-0.3	1.9	1.6	-1.5	-0.5	-1.0
Vitamin and mineral supplements	1.0	1.3	2.8	-1.1	-1.7	0.3	1.5	1.5	-1.1	-1.0	-0.4
Supplements: Zinc	0.5	0.6	1.7	0.2	1.1	1.1	-0.0	0.3	-0.3	-0.6	-1.3
Medication: Co-codamol	1.2	1.4	4.6	0.0	2.1	-0.4	-0.3	0.0	-0.7	-1.4	-1.9
Medication: Metformin	0.1	0.2	0.6	0.3	0.6	-0.8	0.2	-0.4	0.2	0.2	0.1
Diabetes (father)	1.2	1.5	2.7	1.2	-1.1	1.0	-1.6	-1.2	1.5	1.3	0.8
Diabetes (mother)	2.6	3.3	5.6	-2.0	-2.4	0.9	1.9	1.9	-2.0	-2.1	-0.1
Severe depression (siblings)	0.6	0.7	2.0	1.3	0.3	-0.5	0.1	0.8	0.8	-1.4	-0.5
Pack years adult smoking proportion	2.4	3.7	7.2	-2.0	0.2	1.9	2.7	2.1	-1.8	-0.9	-2.5
Impedance of leg (right)	0.5	2.3	5.9	1.7	2.4	0.8	-1.4	-1.7	1.3	-0.7	-1.4
Leg fat-free mass (left)	0.5	2.4	5.0	-1.4	-1.5	-1.0	1.4	2.2	-1.9	-1.8	-0.7
Trunk fat percentage	0.4	1.5	7.2	-0.2	-1.0	-1.1	0.8	1.3	-0.3	-2.7	0.5
Hand grip strength (right)	0.1	0.4	0.9	-0.3	-0.3	-0.9	-0.2	0.9	-0.5	-0.8	-0.7
Townsend deprivation index at recruitment	3.5	5.0	9.7	-2.5	-3.1	1.1	2.5	2.1	-1.8	-2.0	-2.0
Current tobacco smoking	0.9	1.5	3.6	-1.0	-1.9	1.7	1.6	0.9	-0.3	0.1	1.1
Average weekly fortified wine intake	0.2	0.2	0.6	0.8	0.8	-0.5	-0.2	-0.0	0.1	-0.4	-0.5
Maternal smoking around birth	0.4	0.5	1.9	-0.6	1.3	-1.4	-0.1	-0.2	-0.3	0.1	-0.3
Fed-up feelings	1.4	2.6	6.4	-1.5	-0.2	-0.2	1.9	2.1	-1.4	-2.5	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	1.3	0.6	0.5	0.6	-0.9	-1.0	1.1	0.6	0.8
Relative age voice broke	0.8	1.2	3.4	1.4	0.5	-1.0	-1.3	-0.7	1.8	0.8	-0.0
Taking other prescription medications	0.1	0.2	0.5	-0.4	-0.1	0.5	0.5	0.7	-0.4	0.0	0.7
Age when periods started (menarche)	0.5	1.2	2.4	1.3	1.6	-0.5	-1.4	-1.4	0.2	0.3	-0.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	5.2	0.6	0.7	-1.2	0.8	1.0	-0.1	-2.3	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.5	0.9	-0.3	-0.5	-0.4	-0.3	0.4	0.6	1.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.5	-0.1	0.0	-1.2	0.1	0.1	1.1	-0.5	0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.4	-0.6	0.3	-0.2	-0.5	-0.3	-0.4	-0.2	0.0
Serious illness, injury or assault to yourself	6.0	7.3	11.4	-2.7	-1.8	-1.4	3.2	2.7	-3.4	-3.3	-2.4
High blood pressure	0.2	0.6	2.1	-0.4	-0.8	-0.8	0.4	0.0	-0.3	0.8	1.5
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.0	-0.1	1.0	0.2	-0.4	0.1	0.1	1.0	1.0
Multivitamins +/- minerals	1.4	1.7	4.2	1.4	2.0	0.4	-1.5	-1.5	1.4	1.0	0.3
Stomach or abdominal pain in last month	2.3	2.8	10.2	-1.1	-1.5	-3.2	1.2	0.7	-1.3	-2.0	1.1
Supplements: Glucosamine	2.0	2.6	4.8	2.2	1.9	-1.8	-2.1	-1.7	1.4	0.1	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	-0.6	-0.5	-0.2	0.0	-0.2	-0.4	-0.1	0.5
Medication: Atenolol	0.2	0.3	1.0	0.2	-1.0	-1.0	-0.1	0.2	0.2	-0.3	0.3
Medication: Levothyroxine sodium	1.1	1.8	3.5	-1.1	0.2	-1.1	1.4	1.1	-1.6	-1.9	-1.6
Sitting height	0.1	0.8	3.3	0.3	0.5	-0.9	-0.5	-0.4	-0.6	-1.0	-1.8
Chronic bronchitis/emphysema (father)	0.5	0.6	2.3	-0.9	-0.8	1.0	0.3	0.0	0.1	0.1	1.5
High blood pressure (mother)	1.3	1.9	4.4	1.4	0.4	-1.5	-1.9	-2.1	1.2	0.2	1.1
Body mass index (BMI)	0.9	4.0	10.4	-2.2	-0.6	-0.5	2.2	3.2	-2.5	-2.2	-0.2
Impedance of leg (left)	0.5	2.6	6.2	1.9	2.5	0.3	-1.7	-2.1	1.4	-0.4	-1.0
Leg predicted mass (left)	0.5	2.5	5.1	-1.4	-1.5	-1.1	1.4	2.3	-1.9	-1.8	-0.7
Trunk fat mass	0.4	1.9	7.7	-0.4	-1.0	-1.2	1.0	1.7	-0.8	-2.8	-0.1
Waist circumference	0.7	2.6	5.6	-1.5	-1.7	-1.1	1.7	2.1	-1.2	-2.4	-0.3
Number of incorrect matches in round	1.2	1.9	4.6	-1.8	-2.2	0.9	1.7	0.6	-1.1	-1.3	-0.6
Past tobacco smoking	0.5	1.0	3.8	0.7	1.9	-1.7	-0.1	-0.8	0.6	0.0	0.2
Alcohol usually taken with meals	0.6	1.0	2.8	0.7	-0.5	-1.7	-1.2	-0.6	0.5	0.9	-1.2
Nervous feelings	0.5	1.0	2.4	-0.9	-0.4	0.2	1.5	1.2	-0.3	-1.2	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.6	-0.6	-0.6	0.0	1.3	1.2	-0.3	-0.5	-0.5
Hearing difficulty/problems with background noise	0.1	0.2	0.7	-0.6	-0.6	-0.5	-0.0	-0.1	0.2	-0.1	0.9
Hair/balding pattern: Pattern 2	1.4	1.7	6.1	-2.0	-2.5	-1.6	0.8	0.4	-0.5	-0.1	-0.2
Had menopause	1.0	1.2	7.1	0.5	-0.5	0.1	0.8	0.6	0.6	-2.7	-0.9
Had other major operations	0.2	0.2	0.7	0.1	0.2	-0.4	-0.3	0.3	-0.5	-0.9	-0.4
Forced vital capacity (FVC)	0.2	0.8	2.8	0.2	-0.8	1.7	-0.6	-0.5	0.5	1.3	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	1.3	0.3	-0.2	0.0	0.0	0.2	-0.3	0.3	1.1
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	6.1	-1.8	-0.8	-1.2	1.6	2.2	-1.4	-2.5	-0.4
Qualifications: None of the above	0.2	0.5	1.6	0.1	-0.1	-1.3	0.3	0.1	1.0	-0.4	-1.0
Financial difficulties in last 2 years	0.5	0.7	2.0	-1.2	-1.4	-0.4	0.4	0.6	-1.1	-0.1	-0.1
Mouth/teeth dental problems	0.2	0.3	1.8	0.2	-0.3	-0.4	-0.2	-0.2	-1.3	0.1	0.2
Heart attack	0.9	1.2	3.3	1.2	-0.4	-0.2	-1.1	-1.2	1.8	0.5	1.3
Allergy	0.8	1.8	4.0	-1.0	-1.2	-1.2	1.0	0.4	-1.2	-1.9	-2.0
Pain all over the body in last month	0.7	0.8	3.1	1.3	0.4	-1.8	-0.8	-0.6	0.0	-0.1	0.1
Diabetes (self-reported)	0.1	0.1	0.5	-0.1	-0.1	-0.7	0.4	0.5	0.4	0.2	-0.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.7	0.6	-0.5	-0.4	0.2	-0.1	0.8	-0.0	0.6
Medication: Ramipril	0.4	0.5	0.8	0.8	-0.2	0.0	-0.9	-0.7	0.7	0.7	0.8
Medication: Simvastatin	0.6	0.9	3.1	0.9	-0.2	0.1	-0.8	-1.8	0.6	1.1	0.9
Fluid intelligence score	0.2	0.4	1.3	0.0	-0.1	0.9	-0.2	0.6	-0.3	-0.5	1.1
Illnesses of siblings	0.5	0.8	3.7	0.0	0.9	0.1	-0.3	-1.0	0.3	0.8	-1.9
Neuroticism score	0.5	1.1	2.5	-1.0	-0.9	-0.5	1.1	1.6	-0.6	-1.6	-0.4
Weight	0.5	2.2	6.2	-0.9	-0.4	-1.4	1.1	2.1	-1.7	-2.5	-0.6
Impedance of arm (right)	3.3	15.2	32.3	5.0	0.1	-2.3	-4.5	-5.7	5.3	1.8	2.8
Arm fat percentage (right)	0.3	1.3	3.0	-0.5	-1.4	-1.3	0.8	1.3	-0.2	-1.7	0.9
Trunk fat-free mass	0.6	3.3	6.4	-1.8	0.2	-0.6	1.5	2.5	-2.5	-1.7	-2.2
Hip circumference	0.9	3.8	9.6	-1.5	0.6	-0.8	1.7	3.1	-2.1	-3.0	-1.1
Time employed in main current job	1.2	1.4	3.8	0.8	-0.3	-1.1	-1.4	-1.9	1.3	0.9	1.1
Alcohol intake versus 10 years previously	1.0	1.5	5.4	0.2	-0.2	-1.5	1.3	1.4	-0.7	-2.3	-0.3
Father’s age at death	0.3	0.4	1.0	0.3	0.8	1.0	-0.4	-0.4	-0.2	0.6	0.7
Worrier / anxious feelings	0.1	0.2	0.4	-0.1	0.7	-0.2	-0.4	-0.2	0.4	-0.6	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.8	0.3	-0.2	-0.9	-0.7	-0.4	0.8	-0.4	0.2
Falls in the last year	0.2	0.3	0.7	0.5	-0.8	-0.8	-0.1	0.3	0.4	-0.8	-0.5
Hair/balding pattern: Pattern 3	1.5	2.2	4.5	2.1	1.5	-0.4	-1.8	-1.4	1.6	-0.2	1.7
Number of live births	2.8	3.9	9.8	-1.9	-0.9	-0.2	3.1	2.9	-2.2	-1.6	-1.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.5	0.0	-0.7	0.7	-0.1	0.1	0.1	0.7	0.4
Pulse rate	0.3	0.5	2.0	-0.2	0.8	1.4	0.1	0.4	0.0	-0.1	-1.1
Happiness	5.6	6.7	13.0	-3.6	-2.7	2.2	3.1	3.1	-2.6	-1.2	-1.4
Noisy workplace	0.5	0.6	2.2	0.2	-0.7	-1.5	-0.4	-0.2	0.9	0.5	0.8
Qualifications: A levels/AS levels or equivalent	0.6	1.3	4.2	1.1	1.0	0.7	-1.0	-0.8	0.7	2.0	1.4
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	4.7	1.3	2.2	-1.2	-0.8	-0.4	0.9	-0.7	0.5
Mouth/teeth dental problems: Dentures	0.8	1.4	2.5	-1.3	-0.5	1.3	1.4	1.4	-0.2	-1.1	-1.6
Asthma	1.9	3.7	8.9	1.5	1.0	3.0	-1.2	-0.8	1.6	2.8	2.4
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.9	-0.2	0.2	0.6	-0.2	0.1	0.3	0.8	0.9
Medication: Cholesterol lowering	0.3	0.5	1.4	-0.1	-1.2	0.7	0.3	-0.1	0.8	0.8	0.7
Depression (self-reported)	0.5	0.6	1.2	1.1	0.7	-0.3	-0.9	-0.9	1.1	0.6	-0.2
Medication: Lansoprazole	0.7	0.8	2.1	0.9	0.8	-1.1	-0.6	-0.1	-0.3	-1.5	-1.0
Prospective memory result	1.9	2.3	6.9	1.5	1.3	0.5	-2.0	-2.6	1.3	1.3	0.5
Lung cancer (father)	0.3	0.4	2.2	-0.0	1.5	0.5	-0.2	-0.0	0.7	-0.3	-0.0
Illnesses of mother	1.1	1.3	2.6	-1.4	0.9	0.0	1.2	1.5	-1.3	-0.1	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.9	-0.5	-0.4	1.4	0.3	0.6	-0.3	0.2	-0.2
Pulse wave Arterial Stiffness index	0.3	0.3	1.0	0.7	0.1	-0.5	0.2	0.4	-0.5	-1.0	0.5
Impedance of arm (left)	2.7	12.6	27.1	4.4	-0.4	-1.7	-3.8	-5.2	5.0	1.8	3.0
Arm fat mass (right)	0.5	2.2	5.0	-1.2	-1.1	-0.9	1.5	2.1	-1.4	-2.2	0.1
Trunk predicted mass	0.6	3.2	6.3	-1.9	0.1	-0.5	1.5	2.5	-2.5	-1.6	-2.1
Standing height	0.3	2.9	5.7	2.4	0.4	-2.1	-2.1	-2.0	1.5	-0.9	-1.1
Length of working week for main job	1.3	1.5	2.9	-1.1	-0.5	0.4	1.0	1.7	-1.0	-1.5	-1.7
Exposure to tobacco smoke at home	0.5	0.5	2.0	-0.7	-0.7	0.0	1.4	0.7	-0.6	-0.0	-0.7
Breastfed as a baby	0.4	0.5	1.6	0.1	-1.3	1.1	0.5	0.6	0.3	0.3	0.1
Tense / ‘highly strung’	0.6	1.1	2.8	-0.5	-1.7	-0.7	1.4	1.2	0.0	-1.1	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.8	-0.8	-1.4	-1.1	1.7	1.5	-1.1	-1.5	0.2
Hair/balding pattern: Pattern 4	0.3	0.6	1.9	-0.9	-0.0	-0.1	0.9	1.2	-0.1	-1.4	-0.2
Birth weight of first child	0.9	1.6	3.8	-1.3	-0.4	-0.6	1.0	1.4	-1.7	-2.0	-1.1
Peak expiratory flow (PEF)	0.5	1.2	3.5	-0.5	-1.8	-0.2	0.5	0.8	1.0	1.1	1.9
Pulse wave reflection index	1.1	1.3	3.3	1.5	0.1	-1.0	-1.2	-1.4	0.9	0.0	1.8
Ever highly irritable/argumentative for 2 days	2.3	2.8	5.8	-1.6	-2.2	0.1	2.0	2.4	-1.3	-1.9	-0.3
Loud music exposure frequency	0.5	0.5	1.3	-1.1	-0.1	1.1	0.7	0.7	-0.6	-0.6	-0.2
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	3.3	-0.0	0.9	1.4	-0.4	0.1	-0.6	1.2	1.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	2.2	1.2	1.5	-1.2	-1.2	-1.2	0.8	-0.3	0.3
Blood clot in the leg (DVT)	0.7	0.9	1.7	0.8	-0.1	-1.0	-1.2	-1.3	1.1	-0.1	0.9
Medication: Paracetamol	1.1	1.8	3.2	-1.7	-0.3	0.5	1.3	1.8	-1.8	-1.0	-1.3
Headache pain in last month	0.2	0.3	1.2	-0.7	-0.2	-0.5	0.4	0.6	-1.1	0.1	0.2
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.5	0.0	0.6	-0.7	-0.2	-0.0	-0.0	-0.4	-0.3
Glaucoma (self-reported)	0.2	0.2	0.7	-0.3	-0.5	-0.0	0.1	-0.3	0.6	0.4	0.9
Gout (self-reported)	3.0	4.1	10.0	1.7	1.6	-0.3	-3.2	-2.8	1.7	1.9	1.6
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	1.8	-1.1	-0.6	-1.4	1.2	1.2	-1.0	-1.0	-1.3
Medication: Amlodipine	0.9	1.3	4.9	1.5	-0.2	-2.2	-0.1	-0.6	1.4	0.1	0.7
Medication: Ventolin 100micrograms inhaler	2.8	3.6	11.4	0.7	-0.6	2.5	-0.9	-1.1	1.3	2.5	3.4
Birth weight	0.3	0.6	2.7	-0.6	0.1	-1.6	0.4	0.6	-1.0	-0.0	-0.3
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.1	0.0	1.0	-0.0	-0.8	-0.7	0.1	0.7	-0.1
High blood pressure (siblings)	0.3	0.5	2.1	0.4	0.3	0.4	-0.2	0.3	-1.1	-0.3	1.5
Forced vital capacity (FVC), Best measure	0.2	0.9	4.6	-0.8	-0.9	2.1	0.2	0.4	-0.5	0.2	-0.6
Body fat percentage	0.5	1.9	7.7	-0.7	-0.8	-0.8	1.3	1.8	-0.9	-2.8	0.1
Leg fat percentage (right)	1.2	4.2	9.4	-1.7	0.4	0.4	2.2	3.1	-2.5	-2.9	-1.3
Arm fat-free mass (right)	1.4	7.0	13.9	-2.8	-0.0	0.4	2.7	3.7	-3.5	-2.5	-2.8
Exposure to tobacco smoke outside home	0.6	0.8	2.2	0.7	-1.5	-0.3	-0.3	-0.8	1.5	0.4	-0.6
Comparative body size at age 10	0.5	1.5	4.0	-1.9	-2.0	-0.4	0.9	1.2	-0.9	0.2	0.8
Number of full brothers	1.4	1.8	3.9	-2.0	-0.8	-0.5	1.8	1.8	-1.1	-0.7	-1.0
Worry too long after embarrassment	0.1	0.1	0.9	0.2	-0.1	-0.9	0.2	0.4	0.3	-0.0	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.4	1.4	0.9	1.0	0.3	0.0	1.5	-0.9	-0.5
Wheeze or whistling in the chest in last year	0.2	0.4	1.2	0.2	0.5	1.0	0.1	0.2	0.7	0.6	1.1
Number of children fathered	0.2	0.2	0.5	-0.5	-0.2	0.4	0.6	0.7	-0.3	-0.5	0.2
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	5.8	-0.4	1.7	-1.6	0.5	0.6	-1.6	-2.4	0.1
Age at first live birth	0.9	1.6	3.0	1.5	0.1	1.0	-1.7	-0.9	1.2	1.7	1.4
Pulse wave peak to peak time	0.3	0.3	0.9	-0.6	-0.0	0.6	-0.2	-0.4	0.4	0.9	-0.6
Health satisfaction	1.1	1.5	4.0	-1.2	-1.4	-0.4	1.1	2.0	-0.4	-1.7	-0.4
Shortness of breath walking on level ground	0.4	0.5	2.2	-0.2	-0.3	-0.2	-0.2	-0.2	0.5	1.5	1.0
Qualifications: College or University degree	0.6	1.9	5.0	2.2	0.6	0.3	-2.1	-1.2	1.0	0.8	1.4
Eye problems/disorders: None of the above	0.1	0.1	0.5	-0.6	0.3	0.2	0.1	-0.7	0.3	0.1	-0.1
Mouth/teeth dental problems: Loose teeth	1.0	1.2	4.4	0.5	-2.1	0.1	0.2	-0.4	1.3	1.1	1.2
Emphysema/chronic bronchitis	0.4	0.5	1.8	0.7	0.9	1.3	0.2	-0.0	0.3	-0.1	0.6
Medication for pain relief, constipation, heartburn	0.6	1.0	2.0	1.4	0.3	0.5	-1.4	-1.2	1.4	0.9	0.1
Neck or shoulder pain in last month	0.8	1.2	2.7	-0.9	-1.4	-0.2	1.2	1.6	0.3	-0.9	1.3
Medication: Blood pressure	0.2	0.4	0.7	-0.6	-0.7	-0.6	0.9	0.7	-0.6	-0.3	0.0
Angina (self-reported)	0.4	0.5	2.0	-0.2	-1.2	-1.4	0.4	-0.3	-0.3	-0.4	0.1
Migraine (self-reported)	0.2	0.3	0.7	0.6	0.6	-0.5	-0.8	-0.5	0.1	0.3	0.5
Medication: Ibuprofen	0.2	0.2	0.7	-0.2	0.8	-0.8	-0.2	0.3	-0.1	0.2	0.3
Medication: Allopurinol	2.0	2.7	5.1	1.2	0.9	-1.9	-2.2	-2.3	1.9	1.2	0.9
Medication: Omeprazole	1.7	2.0	5.3	-1.2	1.0	0.6	1.2	1.4	-1.9	-1.1	-2.3
Medication: Seretide 50 evohaler	2.4	2.8	5.3	1.3	1.3	1.6	-1.9	-1.5	1.2	2.1	2.3
Mean time to correctly identify matches	0.1	0.3	0.6	0.3	0.1	0.8	0.5	0.1	-0.1	-0.7	-0.8
Heart disease (mother)	0.6	0.7	2.9	0.6	-0.6	-0.7	-0.6	-0.8	0.6	0.4	1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.3	1.1	0.8	-1.0	-0.5	-0.4	1.6	1.2	1.8
Whole body fat mass	0.7	2.8	8.3	-1.2	-1.1	-0.9	1.7	2.4	-1.5	-2.9	-0.3
Leg fat mass (right)	1.1	4.4	9.2	-1.9	-0.4	-0.1	2.1	3.0	-2.6	-3.0	-1.3
Arm predicted mass (right)	1.5	7.4	14.5	-2.9	-0.2	0.6	2.9	3.8	-3.6	-2.5	-2.8
Pulse rate, automated reading	0.2	0.6	1.6	-1.3	-0.1	-0.4	0.6	0.6	-0.8	-0.3	-1.2
Alcohol intake frequency.	0.2	0.4	1.7	-0.8	-0.3	0.3	0.6	0.5	-1.3	-0.5	-0.2
Comparative height size at age 10	0.1	0.6	1.8	0.2	-0.6	-0.8	-0.4	-1.3	0.5	-0.8	-0.9
Number of full sisters	3.0	3.6	7.9	-1.6	0.3	0.5	1.8	2.1	-2.8	-2.5	-2.0
Suffer from ‘nerves’	0.1	0.2	0.5	0.3	-0.0	0.1	0.5	0.7	0.6	0.3	0.6
Overall health rating	1.6	3.4	7.7	-1.7	-2.8	-0.4	2.5	1.9	-1.3	-2.1	-0.9
Chest pain or discomfort	0.4	0.5	3.8	0.2	-0.2	-2.0	0.1	0.2	0.1	-0.4	0.2
Had major operations	0.8	0.9	5.0	0.1	-0.8	-2.2	-0.3	-0.5	0.1	-0.6	0.8
Age at last live birth	0.3	0.4	0.8	0.9	-0.9	0.7	-0.5	-0.3	0.4	0.2	0.6
Family relationship satisfaction	0.5	0.6	1.2	-1.0	-0.8	0.9	0.3	1.1	-0.6	-0.9	-0.4
Leg pain on walking	0.7	0.9	2.6	-1.3	-1.6	-1.4	0.2	0.3	-0.2	-0.6	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	3.1	-1.8	-0.8	0.6	0.6	0.7	-1.1	-0.3	-1.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	4.8	0.6	2.2	-0.3	-0.8	-0.7	-0.0	-0.0	0.0
Illness, injury, bereavement, stress in last 2 years	1.9	2.4	5.6	1.6	0.2	1.0	-1.4	-1.7	2.2	2.4	0.6
Medication: Aspirin	0.4	0.5	2.5	0.2	-0.3	-1.6	0.1	-0.1	-0.1	-0.8	1.0
Supplements: Vitamin C	0.4	0.4	3.0	-0.5	0.3	-1.7	-0.1	0.2	-0.1	0.1	-0.2
Knee pain experienced in last month	1.2	1.9	4.3	1.0	1.2	-2.1	-1.5	-1.7	1.6	-0.2	0.4
Hypertension (Self-reported)	0.2	0.5	1.4	-0.6	-0.8	-0.3	0.6	0.2	-0.3	0.8	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	5.5	0.1	2.0	-1.4	0.7	1.2	-0.9	-2.3	-0.6
Illnesses of father: Heart disease	1.5	2.1	4.0	2.0	1.0	-0.1	-1.2	-1.6	1.9	1.3	1.6
Illnesses of siblings: Diabetes	0.4	0.5	1.7	1.0	0.2	-0.8	-0.3	0.0	0.5	-0.2	1.3
Smoking status: Previous	0.3	0.4	1.5	-0.4	-0.6	1.2	-0.1	0.6	-0.6	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.1	-0.9	-0.1	-1.0	0.1	0.1	-1.1	-1.0	-0.9
Whole body fat-free mass	0.6	3.4	6.8	-1.9	-0.5	-0.7	1.6	2.6	-2.5	-2.0	-1.8
Leg fat-free mass (right)	0.3	1.5	2.8	-1.1	-1.5	-1.3	1.0	1.7	-1.4	-1.2	-0.2
Arm fat percentage (left)	0.4	1.5	3.2	-0.7	-1.6	-0.8	1.2	1.6	-0.4	-1.8	1.0
Average weekly red wine intake	0.1	0.2	0.4	0.3	-0.2	-0.1	-0.6	-0.2	-0.3	0.7	0.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	1.0	-0.8	-0.5	-0.4	-1.2	-0.0	-0.9	-0.7
Mood swings	0.3	0.6	3.0	-0.4	-0.2	0.2	0.9	0.8	-0.4	-1.7	-0.4
Loneliness, isolation	0.7	1.0	3.4	-0.4	-1.5	0.4	0.9	1.9	-0.1	-1.0	-0.0
Long-standing illness, disability or infirmity	0.3	0.4	0.9	-0.8	-0.6	-0.2	0.8	0.5	-0.6	-1.0	-0.4
Ever had bowel cancer screening	0.6	0.7	1.5	0.1	0.4	-1.2	1.0	1.0	-0.2	-0.7	1.1
Diabetes diagnosed by doctor	0.1	0.1	0.4	-0.3	-0.2	-0.4	0.6	0.5	-0.1	-0.4	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.7	-0.8	0.6	-0.3	0.3	1.3	-1.9	-0.5	-1.9
Friendships satisfaction	0.4	0.4	2.6	0.3	0.5	1.6	-0.6	0.1	0.1	0.3	0.4
Qualifications: nursing, teaching	1.7	2.6	7.0	2.2	1.6	0.4	-1.3	-0.8	1.3	1.5	2.6
Commuting to job workplace: Walk	2.5	2.7	8.7	1.1	-0.8	0.4	-1.5	-1.2	2.3	2.9	1.6
Eye problems/disorders: Cataract	1.0	1.2	5.1	0.9	-1.3	-2.3	-0.0	0.8	0.9	0.6	0.3
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	4.2	-0.8	0.7	-0.0	0.3	0.3	0.1	1.1	2.1
Medication for cholesterol	1.2	1.8	4.1	1.6	1.2	1.2	-2.0	-1.5	1.4	0.4	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.7	-1.1	-1.6	-0.3	1.5	1.0	-0.1	-0.5	0.4
Back pain experienced in last month	1.1	1.6	4.4	0.3	1.8	-1.3	-0.7	-0.5	-0.6	-2.1	-1.5
Mineral and other dietary supplements	0.9	1.2	5.5	-1.0	-2.3	0.8	0.9	1.0	-0.6	-0.1	0.0
Breast cancer (self-reported)	1.5	1.7	5.0	0.8	1.5	-0.8	-0.3	-0.4	0.8	-2.1	-2.2
Asthma (self-reported)	1.9	3.8	8.0	1.6	0.9	2.8	-1.2	-0.8	1.6	2.8	2.6
Osteoporosis (self-reported)	0.8	1.0	3.9	0.6	0.4	2.0	-0.4	-0.3	0.7	1.1	1.1
Osteoarthritis (self-reported)	0.4	0.5	1.8	-0.3	-0.3	0.4	0.5	1.4	0.4	-0.8	-1.0
Medication: Aspirin	0.4	0.5	1.9	-0.1	-0.6	-1.4	0.5	0.5	-0.2	-0.5	1.0
Medication: Gliclazide	0.6	0.7	2.7	0.9	0.9	-1.6	-0.5	-0.3	0.5	-0.3	0.4
Illnesses of father: None of the above (group 1)	3.4	4.2	8.2	-2.9	-1.9	-0.4	2.4	2.9	-2.2	-0.9	-1.4
Smoking status: Current	0.8	1.2	3.4	-0.7	-1.8	1.7	1.3	0.8	-0.2	0.1	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	4.5	-2.1	-1.1	1.2	1.6	1.9	-0.8	-0.5	-1.3
Whole body water mass	0.6	3.6	7.6	-1.9	-0.5	-0.6	1.8	2.8	-2.6	-1.9	-1.8
Leg predicted mass (right)	0.3	1.5	2.8	-1.0	-1.5	-1.3	1.0	1.7	-1.4	-1.2	-0.2
Arm fat mass (left)	0.6	2.3	5.2	-1.3	-1.3	-0.8	1.7	2.3	-1.4	-2.2	0.2
Number of self-reported non-cancer illnesses	0.3	0.4	1.5	-0.8	-0.2	-1.2	0.5	0.6	-0.5	0.3	0.5
Average weekly champagne plus white wine intake	1.9	2.5	5.3	1.5	1.3	-1.1	-2.3	-2.1	1.5	1.8	0.6
Miserableness	0.3	0.6	1.2	-1.0	0.3	-0.8	0.7	1.1	-0.6	-0.8	-0.5
Guilty feelings	0.3	0.4	1.1	-0.2	0.1	-1.0	-0.2	0.8	0.8	-0.5	-0.7
Wears glasses or contact lenses	0.9	1.0	3.8	1.5	2.0	0.0	-0.8	-0.2	0.7	-0.4	0.9
Ever taken oral contraceptive pill	0.6	0.7	1.7	-1.0	-0.0	-0.3	-0.5	-0.2	-1.1	1.3	1.1
Hearing aid user	0.1	0.1	0.5	-0.2	0.4	0.3	-0.2	-0.4	0.7	0.0	-0.2
Mother’s age at death	0.4	0.5	1.8	0.8	-0.2	1.3	-0.5	-0.4	0.3	0.6	0.8
Financial situation satisfaction	2.0	2.4	3.8	-1.9	-1.9	0.1	1.9	1.7	-1.6	-0.9	-1.4
Tinnitus: Yes, now most or all of the time	1.9	2.2	3.9	-1.6	-0.9	1.6	1.7	1.8	-1.1	-2.0	-1.1
Commuting to job workplace: Public transport	1.0	1.2	4.3	0.1	-2.1	1.2	0.6	0.7	-0.2	0.4	1.6
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	-0.2	-0.5	0.8	0.2	-0.0	0.3	-0.1	0.7
Medication: Blood pressure	0.2	0.4	1.2	0.3	-0.4	-0.8	-0.2	-0.8	0.6	0.3	1.1
Pain type(s) experienced in last month: Hip pain	1.2	1.5	6.1	-1.4	-2.5	0.4	1.0	0.8	-0.1	-0.6	1.4
Supplements: Fish oil (including cod liver oil)	0.9	1.1	5.6	1.1	2.4	-0.8	-0.8	-0.9	-0.0	-0.1	0.2
High cholesterol (Self-reported)	0.1	0.1	0.7	0.2	0.3	-0.1	-0.0	-0.2	-0.2	-0.8	-0.4
Medication: Bendroflumethiazide	0.1	0.2	0.5	-0.5	-0.5	-0.3	0.7	0.2	-0.4	-0.6	-0.4
Medication: Paracetamol	0.4	0.6	1.4	-0.9	-0.1	0.2	0.7	1.2	-1.1	-0.5	-0.7
Medication: Lisinopril	1.3	1.7	3.7	-1.7	-0.4	1.9	1.5	1.3	-1.6	-0.4	-0.4
Medication: Atorvastatin	0.2	0.2	0.9	-0.1	-0.6	-1.0	-0.0	0.0	0.5	-0.2	0.4
Illnesses of father: High blood pressure	0.6	0.8	4.0	0.6	0.4	-2.0	-0.9	-0.7	-0.3	-0.6	-0.1
Alcohol drinker status: Never	0.4	0.5	1.3	0.4	0.6	-0.6	-1.1	-1.0	-0.9	-0.1	-0.5
Ever smoked	0.9	1.6	7.8	-0.5	-2.8	1.7	0.7	1.2	-0.5	0.0	0.1
Basal metabolic rate	0.6	3.5	7.5	-1.8	-0.5	-0.9	1.7	2.7	-2.5	-2.2	-1.6
Leg fat percentage (left)	0.9	3.3	7.6	-1.4	0.4	-0.1	1.9	2.8	-2.2	-2.7	-1.0
Arm fat-free mass (left)	1.2	6.0	12.0	-2.5	0.3	-0.0	2.2	3.5	-3.3	-2.6	-2.7
Number of operations (self-reported)	0.5	0.7	2.9	0.4	-0.3	-1.7	-0.2	-0.4	0.6	-0.1	1.3
Average weekly beer plus cider intake	0.6	0.8	2.5	1.6	0.9	-0.7	-0.7	-0.5	0.6	-0.4	1.2
Irritability	0.7	1.1	4.4	0.4	-0.2	-1.4	0.6	0.8	-0.5	-2.1	1.2
Risk taking	0.3	0.4	1.6	0.6	0.3	0.3	-0.7	-1.3	0.2	0.1	0.6
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.6	0.2	-0.1	1.6	-0.0	-0.3	0.7	1.2	1.4
Fractured/broken bones in last 5 years	0.9	1.1	2.6	-1.0	-0.4	1.4	1.1	1.4	-1.6	0.1	0.3
Age started oral contraceptive pill	2.0	2.4	7.3	2.3	0.2	-0.4	-1.5	-2.0	2.7	0.7	0.4
Diastolic blood pressure, automated reading	0.3	0.9	2.4	-1.4	-1.6	-1.2	0.6	0.4	-0.2	1.0	0.5
Ever depressed for a whole week	1.2	1.5	2.6	-0.5	-1.2	-1.1	1.3	1.6	-1.4	-1.6	-0.3
Unable to work because of sickness or disability	0.2	0.3	1.4	-0.2	-0.5	-0.1	-0.2	-1.2	0.7	0.2	0.4
Commuting to job workplace: Cycle	2.2	2.7	5.8	1.4	0.7	0.2	-2.4	-2.1	2.1	1.7	1.3
Myopia	0.3	0.4	0.8	0.8	-0.8	-0.1	-0.9	-0.4	0.8	0.3	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.7	2.2	0.3	0.6	1.1	0.1	0.6	0.1	-1.0	-1.5
Cholesterol lowering medication	0.4	0.6	2.2	0.5	0.6	-1.5	-0.0	-0.5	-1.0	-0.9	0.3
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.6	-0.8	0.9	-0.1	0.8	0.9	-1.6	-1.2	-2.1
Pain experienced in last month	2.0	3.3	15.8	-1.4	-1.5	4.0	1.5	1.1	-1.0	1.0	-1.0
Supplements: Calcium	0.9	1.0	3.1	1.1	-0.2	-0.7	0.4	-0.0	1.8	0.8	1.6
Basal cell carcinoma (self-reported)	1.9	2.2	5.3	-1.2	-2.1	-0.9	2.3	1.7	-1.5	-0.6	-0.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.4	1.3	-0.3	-0.2	-1.2	-1.2	1.8	0.6	1.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.9	1.0	0.2	-1.1	-1.2	-1.4	1.2	-0.1	0.7
Heart disease (siblings)	0.2	0.2	0.7	0.5	-0.1	-0.8	-0.3	-0.1	0.5	0.1	0.8
Alcohol drinker status: Previous	0.2	0.2	1.3	-0.1	0.0	1.2	-0.0	-0.2	-0.1	0.3	-0.0
Pack years of smoking	1.9	2.7	5.9	-1.6	0.2	1.2	2.4	1.9	-1.3	-1.0	-2.4
Impedance of whole body	1.2	6.3	15.7	3.3	0.7	-0.8	-2.8	-4.0	3.6	0.7	1.2
Leg fat mass (left)	1.0	3.9	8.8	-1.7	-0.3	-0.5	2.0	2.9	-2.4	-3.0	-1.1
Arm predicted mass (left)	1.3	6.4	12.7	-2.6	0.1	0.2	2.4	3.5	-3.6	-2.5	-2.6