Best TWAS P=1.55e-11 · Best GWAS P=4.75e-12 conditioned to 0.000359
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | QSOX2 | 0.18 | 0.11 | lasso | 4 | 0.10 | 1.0e-12 | 6.2 | 5.5 | 3.6e-08 | 0.52 | 0.08 | 0.92 | FALSE |
| 2 | GTEx | Esophagus Muscularis | QSOX2 | 0.16 | 0.07 | lasso | 4 | 0.06 | 1.4e-04 | 6.4 | 6.7 | 1.6e-11 | 0.60 | 0.04 | 0.92 | TRUE |
| 3 | GTEx | Nerve Tibial | QSOX2 | 0.22 | 0.12 | enet | 12 | 0.17 | 4.6e-12 | 5.6 | 5.3 | 1.4e-07 | 0.45 | 0.40 | 0.60 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | QSOX2 | 0.06 | 0.05 | lasso | 2 | 0.05 | 2.5e-06 | 6.2 | 5.6 | 2.1e-08 | 0.52 | 0.08 | 0.83 | FALSE |