TWAS
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Models
Genes
Traits
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Traits
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Impedance of arm (right)
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chr9:138,403,706-139,836,362
Best TWAS P=1.55e-11 · Best GWAS P=4.75e-12 conditioned to 0.000359
138.4M
138.6M
138.8M
139M
139.2M
139.4M
139.6M
139.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Muscularis
QSOX2
0.16
0.07
lasso
4
0.06
1.4e-04
6.4
6.7
1.6e-11
0.60
0.04
0.92
TRUE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
QSOX2
0.06
0.05
lasso
2
0.05
2.5e-06
6.2
5.6
2.1e-08
0.52
0.08
0.83
FALSE
1
CommonMind
Brain Pre-frontal Cortex
QSOX2
0.18
0.11
lasso
4
0.10
1.0e-12
6.2
5.5
3.6e-08
0.52
0.08
0.92
FALSE
3
GTEx
Nerve Tibial
QSOX2
0.22
0.12
enet
12
0.17
4.6e-12
5.6
5.3
1.4e-07
0.45
0.40
0.60
FALSE