[Hub]/) : Traits : Impedance of arm (right) :

chr1:201,158,976-202,632,057

Best TWAS P=3.04e-15 · Best GWAS P=1.3e-15 conditioned to 0.00142

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SHISA4 0.09 0.04 lasso 3 0.03 1.5e-03 5.92 6.9 7.1e-12 -0.57 0.20 0.34 FALSE
2 GTEx Colon Transverse TIMM17A 0.17 0.07 enet 11 0.09 5.1e-05 -4.40 -5.3 9.5e-08 0.30 0.34 0.06 FALSE
3 GTEx Esophagus Muscularis LMOD1 0.16 0.09 enet 9 0.08 7.8e-06 -8.00 7.5 7.7e-14 -0.99 0.01 0.99 FALSE
4 GTEx Esophagus Muscularis RP11-307B6.3 0.20 0.12 lasso 3 0.12 5.6e-08 -8.00 7.4 1.7e-13 -0.98 0.01 0.99 FALSE
5 METSIM Adipose LMOD1 0.09 0.07 bslmm 496 0.07 4.8e-10 -7.89 7.9 3.1e-15 -0.97 0.01 0.99 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma SHISA4 0.03 0.01 enet 5 0.00 2.5e-01 7.27 6.6 4.7e-11 -0.56 0.04 0.17 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma LMOD1 0.02 0.01 blup 59 0.02 1.2e-04 -7.93 6.6 5.5e-11 -0.86 0.01 0.96 FALSE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LMOD1 0.07 0.06 blup 59 0.03 2.1e-02 -7.91 7.3 3.9e-13 -0.90 0.01 0.86 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma LMOD1 0.04 0.07 enet 6 0.05 9.4e-07 7.27 7.9 3.0e-15 -0.74 0.22 0.78 TRUE
10 The Cancer Genome Atlas Lung Adenocarcinoma LMOD1 0.04 0.01 blup 59 0.01 5.7e-02 -7.79 6.4 1.9e-10 -0.83 0.01 0.81 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma LMOD1 0.08 -0.01 blup 59 0.01 1.3e-01 0.41 5.6 2.7e-08 -0.78 0.01 0.47 FALSE