TWAS hub - SHISA4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3030	0.0440	0.0e+00	0.222	0.139	0.194	0.208	0.211	1.4e-26	1.4e-16	4.0e-23	8.6e-25	3.1e-25
2	GTEx	Adipose Subcutaneous	0.0930	0.0330	2.0e-03	0.037	NA	0.028	NA	0.030	4.8e-04	NA	2.1e-03	NA	1.5e-03
3	GTEx	Brain Caudate basal ganglia	0.3090	0.1040	7.0e-03	0.198	NA	0.093	NA	0.159	2.4e-06	NA	1.2e-03	NA	2.6e-05
4	GTEx	Brain Nucleus accumbens basal ganglia	0.4260	0.1010	3.8e-04	0.079	NA	0.016	NA	0.015	3.9e-03	NA	1.2e-01	NA	1.3e-01
5	GTEx	Cells Transformed fibroblasts	0.1900	0.0470	8.8e-06	0.053	NA	0.106	NA	0.093	7.7e-05	NA	2.4e-08	NA	1.9e-07
6	GTEx	Colon Sigmoid	0.2790	0.0970	4.9e-03	0.009	NA	0.012	NA	0.029	1.5e-01	NA	1.2e-01	NA	3.3e-02
7	GTEx	Nerve Tibial	0.4242	0.0522	5.6e-17	0.312	NA	0.373	NA	0.375	1.5e-22	NA	1.2e-27	NA	7.5e-28
8	GTEx	Thyroid	0.4700	0.0450	0.0e+00	0.453	NA	0.457	NA	0.466	3.7e-38	NA	1.6e-38	NA	1.3e-39
9	TCGA	Bladder Urothelial Carcinoma	0.0340	0.0210	6.3e-03	0.008	0.000	0.001	NA	0.000	6.0e-02	3.0e-01	2.5e-01	NA	3.4e-01
10	TCGA	Breast Invasive Carcinoma	0.0234	0.0132	1.1e-03	0.023	0.018	0.012	NA	0.021	1.0e-05	9.9e-05	1.2e-03	NA	3.4e-05
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.0507	0.0297	2.6e-04	0.012	0.033	0.029	NA	0.024	1.6e-02	1.1e-04	2.7e-04	NA	1.0e-03
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.1197	0.0476	2.3e-10	0.096	0.099	0.100	NA	0.101	5.7e-11	2.9e-11	2.3e-11	NA	1.9e-11
13	TCGA	Brain Lower Grade Glioma	0.2228	0.0769	0.0e+00	0.204	0.200	0.208	NA	0.198	9.6e-23	2.7e-22	3.9e-23	NA	4.6e-22
14	TCGA	Pancreatic Adenocarcinoma	0.1030	0.0640	8.1e-03	0.005	0.016	0.002	NA	0.005	2.0e-01	7.0e-02	2.7e-01	NA	1.9e-01
15	TCGA	Skin Cutaneous Melanoma	0.2200	0.1210	3.4e-03	0.135	0.077	0.040	NA	0.099	1.9e-04	4.2e-03	3.1e-02	NA	1.4e-03
16	TCGA	Stomach Adenocarcinoma	0.0980	0.0510	7.1e-05	0.061	0.063	0.041	NA	0.061	3.3e-05	2.5e-05	5.9e-04	NA	3.1e-05
17	TCGA	Thyroid Carcinoma	0.2970	0.0740	0.0e+00	0.348	0.338	0.348	NA	0.348	5.2e-35	7.9e-34	5.1e-35	NA	4.8e-35

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Number of incorrect matches in round	10.0	16.6	26.9	4.7	1.3	5.2	4.2	4.2	1.4	4.2	4.8	1.8	4.6	3.6	4.4	4.2	4.2	4.8	3.9	4.7
Fasting Glucose	7.1	8.5	12.0	-3.2	-2.5	-3.2	-3.1	-2.5	-2.3	-3.1	-3.0	-2.1	-2.8	-3.4	-2.8	-3.5	-2.9	-3.2	-2.6	-2.9
Pulse rate	6.4	10.8	17.0	4.1	1.1	3.9	1.0	2.8	1.2	3.7	4.1	1.1	4.1	2.8	4.0	3.3	3.4	4.1	3.5	4.1
Pulse rate, automated reading	6.2	20.1	33.3	5.7	0.8	5.7	1.5	3.6	1.5	4.8	5.8	1.0	5.6	3.3	5.2	4.4	4.8	5.7	5.0	5.8
Alzheimer’s Disease (in mother)	4.9	5.7	9.1	-2.8	-1.6	-3.0	-1.5	-1.6	-1.1	-2.6	-2.7	-1.2	-2.6	-2.6	-2.5	-2.6	-2.9	-2.8	-2.4	-2.7
Medication: Ramipril	3.6	4.6	13.0	-1.7	-2.8	-1.9	-2.5	-3.6	-0.5	-2.3	-1.6	-2.3	-1.9	-2.7	-1.8	-2.6	-1.9	-1.7	-1.4	-1.8
Ever had prostate specific antigen (PSA) test	3.6	4.1	9.2	-2.1	-1.5	-2.0	-1.1	-1.6	-3.0	-2.4	-2.1	-1.0	-2.2	-2.0	-2.5	-2.4	-1.7	-2.1	-1.7	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.4	4.0	6.9	2.6	-0.2	2.1	0.9	1.2	0.4	2.0	2.6	0.4	2.5	1.5	2.2	2.0	2.5	2.6	2.6	2.6
Alzheimer’s Disease (including proxy)	3.3	4.8	7.1	-2.2	-2.7	-2.4	-1.7	-2.0	-1.3	-2.6	-2.2	-2.2	-2.3	-2.4	-2.1	-2.6	-2.1	-2.2	-1.3	-2.2
Medication: Paracetamol	3.3	5.2	15.8	-1.6	-3.7	-1.4	-2.1	-2.4	-2.2	-2.5	-1.2	-4.0	-1.5	-3.3	-1.1	-2.5	-2.5	-1.5	-0.5	-1.4
Falls in the last year	2.9	3.9	7.7	-1.8	-2.2	-2.0	-1.3	-2.0	-2.1	-2.2	-1.7	-2.0	-1.8	-2.6	-1.5	-2.0	-2.8	-1.8	-1.6	-1.9
Mean time to correctly identify matches	2.8	5.4	13.1	2.6	0.6	2.5	1.6	1.3	-1.1	2.3	2.5	2.1	2.5	2.5	1.7	2.2	3.6	2.6	3.1	2.6
Cardiovascular Disease	2.6	8.7	28.0	-1.7	-5.3	-1.3	-4.0	-4.2	0.3	-3.1	-1.5	-4.7	-2.1	-4.0	-1.6	-3.0	-2.9	-1.7	-0.6	-1.8
Fed-up feelings	2.6	4.7	17.6	-1.6	-3.5	-1.2	-1.7	-2.4	0.8	-2.5	-1.3	-4.2	-1.7	-3.1	-1.1	-2.3	-2.2	-1.5	-0.4	-1.5
Diverticular disease/diverticulitis (self-reported)	2.6	3.1	5.2	-1.9	-0.5	-2.2	-1.5	-1.5	-1.1	-1.6	-1.9	-0.3	-1.8	-1.9	-1.7	-1.9	-2.2	-1.9	-2.3	-1.9
Body mass index (BMI)	2.6	11.0	58.1	2.0	-7.6	1.7	-3.4	-4.6	-0.5	-0.8	2.4	-6.7	1.3	-2.9	1.1	-1.2	0.6	2.0	4.1	1.9
Medication: Lisinopril	2.6	3.4	7.7	2.1	-1.0	2.2	1.6	0.8	2.3	1.4	2.1	-1.6	1.9	1.0	2.3	1.3	1.5	2.0	2.8	2.0
Ever had hysterectomy (womb removed)	2.5	2.8	6.5	2.2	-0.2	2.2	1.3	-0.6	0.8	1.8	2.5	-1.0	2.2	0.2	2.3	1.3	0.4	2.3	1.5	2.3
High blood pressure (siblings)	2.5	3.6	8.9	-1.3	-3.0	-1.4	-2.2	-2.9	0.1	-2.0	-1.3	-2.7	-1.7	-2.4	-1.4	-2.1	-2.0	-1.3	-0.4	-1.5
Leg fat mass (right)	2.5	9.7	49.1	1.4	-7.0	1.1	-3.5	-5.0	-0.8	-1.0	1.9	-6.5	0.9	-3.4	0.8	-1.4	-0.5	1.5	3.2	1.4
Ever had bowel cancer screening	2.5	3.0	5.4	2.1	1.2	2.3	1.9	0.9	-1.1	1.8	2.0	1.5	1.9	1.7	1.4	1.5	1.8	2.0	1.5	1.9
Leg fat mass (left)	2.5	9.7	48.7	1.6	-7.0	1.2	-3.3	-4.8	-0.9	-1.0	2.0	-6.5	1.1	-3.3	1.0	-1.3	-0.4	1.6	3.4	1.6
Reaction Time	2.4	4.6	8.4	2.3	1.2	2.4	2.0	1.9	-0.6	2.3	2.1	2.3	2.1	2.4	1.7	2.2	2.9	2.2	2.4	2.2
Prostate Cancer	2.3	3.3	6.0	1.8	1.7	1.7	1.8	2.0	0.7	2.0	1.7	1.6	1.7	2.4	1.4	1.9	2.2	1.9	1.6	1.8
BMI	2.3	13.5	58.8	3.2	-7.7	3.1	-2.4	-3.7	0.4	0.2	3.7	-6.9	2.5	-1.9	2.7	0.0	1.4	3.3	5.3	3.2
Health satisfaction	2.2	2.8	13.4	1.4	-3.5	1.6	-0.3	-0.9	0.2	-0.0	1.5	-3.7	1.0	-1.2	1.2	-0.3	0.4	1.4	2.7	1.3
Guilty feelings	2.2	3.3	17.6	-1.2	-2.7	-0.7	-1.0	-1.3	0.3	-2.0	-0.8	-4.2	-1.3	-2.8	-0.5	-1.3	-2.7	-1.0	-0.5	-1.2
Leg fat percentage (left)	2.2	7.8	33.7	1.6	-5.7	0.9	-3.2	-4.6	-0.7	-0.6	2.0	-5.8	1.3	-3.2	1.2	-0.7	-0.8	1.6	2.7	1.6
Lung FEV1/FVC ratio	2.1	10.5	36.5	1.2	6.0	1.4	5.1	5.7	2.5	3.5	1.0	5.7	1.7	2.6	1.4	3.1	0.5	1.2	-2.1	1.1
Arm fat mass (right)	2.1	8.4	46.7	1.6	-6.8	1.5	-3.1	-4.1	-1.0	-0.8	2.0	-5.6	1.0	-2.6	0.8	-1.3	0.4	1.7	3.5	1.6
Blood clot in the leg (DVT)	2.1	2.7	6.4	-1.1	-2.5	-1.3	-1.7	-2.1	-0.9	-1.8	-1.2	-2.1	-1.5	-1.9	-1.6	-2.0	-1.4	-1.3	-0.9	-1.3
Medication: Paracetamol	2.1	3.5	15.1	-0.9	-3.7	-0.7	-1.7	-1.7	-1.6	-1.8	-0.5	-3.9	-0.7	-2.9	-0.4	-1.8	-2.0	-0.8	0.1	-0.7
Leg fat percentage (right)	2.1	7.5	32.1	1.4	-5.7	0.8	-3.4	-4.7	-0.5	-0.6	1.8	-5.6	1.1	-3.2	1.1	-0.8	-0.9	1.5	2.5	1.4
Long-standing illness, disability or infirmity	2.1	3.2	7.4	-1.1	-2.6	-1.1	-1.3	-2.7	-2.5	-1.8	-1.0	-2.6	-1.2	-2.4	-0.8	-2.1	-1.9	-1.1	-0.5	-1.1
Arm fat mass (left)	2.1	8.6	48.3	1.4	-7.0	1.2	-3.2	-4.3	-1.1	-1.0	1.8	-5.8	0.7	-2.9	0.6	-1.5	0.0	1.5	3.2	1.3
Neuroticism (Nagel 2018)	2.0	4.7	26.2	-1.0	-3.8	-0.8	-0.5	-2.1	-0.6	-2.0	-0.9	-5.1	-1.2	-3.4	-0.3	-1.8	-3.0	-1.0	-0.1	-1.1
Pulse wave reflection index	2.0	2.5	4.2	-1.5	-1.6	-1.7	-2.1	-1.7	-0.9	-1.8	-1.4	-2.0	-1.4	-1.8	-1.4	-1.8	-1.4	-1.5	-0.8	-1.4
Ever highly irritable/argumentative for 2 days	2.0	2.3	8.8	-1.1	-2.5	-1.0	-1.6	-2.0	0.9	-1.9	-1.0	-3.0	-1.3	-1.6	-0.8	-1.5	-0.9	-1.1	0.3	-1.1
Whole body fat mass	2.0	8.2	44.2	1.3	-6.6	0.9	-3.1	-4.5	-1.3	-1.1	1.6	-5.7	0.7	-3.1	0.5	-1.5	-0.2	1.3	2.9	1.2
Qualifications: NVQ or HND or HNC or equivalent	2.0	2.4	7.5	-1.1	-2.1	-1.6	-1.5	-2.1	0.3	-1.8	-1.1	-2.7	-1.2	-1.9	-0.8	-1.5	-1.8	-1.2	-0.1	-1.1
Medication: Atorvastatin	2.0	2.5	5.1	-1.5	-1.1	-1.7	-2.3	-1.8	0.1	-1.5	-1.6	-1.0	-1.5	-1.8	-1.5	-1.9	-1.8	-1.5	-1.7	-1.6
Deep venous thrombosis (DVT) (self-reported)	2.0	2.5	6.3	-1.1	-2.5	-1.2	-1.8	-2.0	-1.1	-1.7	-1.2	-2.1	-1.4	-1.8	-1.5	-1.9	-1.2	-1.2	-0.7	-1.2
Bipolar Disorder or Schizophrenia	1.9	4.6	7.3	2.4	1.9	2.4	2.6	1.9	0.3	2.5	2.5	1.0	2.7	1.7	2.6	2.6	1.4	2.4	1.4	2.5
Waist circumference	1.9	6.8	39.4	0.9	-6.3	0.8	-2.9	-4.4	-1.0	-1.1	1.2	-5.0	0.3	-2.8	0.1	-1.6	-0.0	0.9	2.6	0.8
Weight	1.9	9.3	57.1	1.0	-7.6	1.1	-3.2	-4.5	-1.1	-1.5	1.4	-6.0	0.4	-3.0	0.0	-2.1	0.3	1.1	3.3	1.0
Hip circumference	1.9	8.3	48.6	0.3	-7.0	0.2	-3.3	-4.7	-1.0	-1.9	0.6	-5.7	-0.4	-3.4	-0.5	-2.2	-0.7	0.3	2.2	0.2
Supplements: Fish oil (including cod liver oil)	1.9	2.5	4.1	1.9	0.6	2.0	1.5	1.4	0.5	1.8	2.0	0.7	1.8	1.0	1.7	1.8	1.4	1.9	1.7	1.8
Diastolic blood pressure, automated reading	1.9	5.8	28.5	1.1	-5.3	0.9	-3.0	-3.1	-0.3	-1.2	1.4	-5.3	0.9	-2.3	1.1	-1.1	-0.4	1.1	2.6	1.1
Ever depressed for a whole week	1.9	2.3	3.3	1.8	0.7	1.8	1.8	1.5	1.2	1.4	1.7	-0.2	1.6	1.6	1.8	1.4	1.4	1.7	1.8	1.7
Body Mass Index (BMI) (2010)	1.8	2.5	10.8	-0.1	-3.3	-0.2	-2.2	-2.6	-1.5	-1.5	-0.1	-2.2	-0.5	-2.2	-1.0	-1.9	-0.5	-0.2	0.3	-0.3
Heel T-Score	1.8	14.4	38.6	-4.2	-1.1	-4.0	-2.5	-2.9	-0.5	-3.6	-4.0	-2.0	-3.8	-4.8	-3.4	-3.4	-6.2	-4.1	-5.4	-4.1
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	5.9	-2.0	-2.0	-1.8	-1.4	-2.2	-1.9	-2.1	-2.1	-1.2	-2.0	-2.4	-1.9	-2.0	-2.4	-2.0	-2.0	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.2	7.6	-2.1	-1.5	-1.9	-1.7	-2.5	-1.4	-2.0	-2.1	-1.4	-2.0	-2.6	-1.8	-2.0	-2.8	-2.1	-2.4	-2.1
Impedance of arm (right)	1.8	8.6	47.1	-0.8	6.9	-0.6	3.2	4.2	0.0	1.7	-1.0	6.6	-0.2	2.9	-0.2	1.8	-0.2	-0.8	-3.1	-0.7
Illnesses of mother	1.8	2.2	3.3	1.5	1.8	1.5	1.4	1.6	1.1	1.8	1.5	1.3	1.7	1.3	1.5	1.7	1.2	1.6	0.6	1.6
Impedance of arm (left)	1.8	8.1	40.8	-1.8	6.4	-1.4	2.6	3.6	0.3	0.8	-1.9	5.8	-1.2	1.8	-1.0	1.0	-1.6	-1.7	-4.3	-1.8
Shortness of breath walking on level ground	1.8	2.1	12.0	0.8	-2.8	0.6	-1.9	-1.3	-0.5	-0.2	1.0	-3.5	0.5	-1.6	0.9	-0.6	-0.6	0.8	1.7	0.8
Qualifications: nursing, teaching	1.8	2.8	9.2	-1.4	3.0	-1.7	0.8	1.2	-0.8	-0.2	-1.8	2.4	-1.2	0.1	-1.2	-0.3	-2.0	-1.7	-3.0	-1.6
Ever used hormone-replacement therapy (HRT)	1.7	2.2	3.7	1.7	0.6	1.9	1.9	1.0	0.8	1.6	1.9	0.0	1.9	1.0	1.9	1.4	0.9	1.8	1.1	1.9
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.7	19.5	0.5	-3.1	0.6	-1.4	-1.2	1.0	-0.7	0.7	-4.4	0.2	-2.5	0.8	-0.6	-1.6	0.4	1.1	0.4
Worry too long after embarrassment	1.7	2.9	10.8	-1.3	-2.4	-1.2	-1.0	-1.4	-0.1	-2.1	-1.3	-3.3	-1.5	-2.4	-0.7	-1.6	-2.4	-1.4	-0.3	-1.5
Illnesses of father: High blood pressure	1.7	2.1	3.5	1.9	0.9	1.7	1.0	0.8	0.5	1.8	1.8	-0.2	1.6	1.2	1.9	1.8	1.0	1.8	1.4	1.7
Alcohol drinker status: Never	1.7	2.1	3.8	-1.7	-0.4	-1.7	-0.9	-1.0	-0.4	-1.5	-1.7	0.3	-1.8	-1.4	-1.9	-1.8	-1.1	-1.7	-1.5	-1.8
Number of operations (self-reported)	1.7	2.5	10.2	-0.7	-2.1	-1.3	-1.2	-3.2	-2.4	-1.5	-0.8	-2.3	-1.2	-1.7	-0.8	-1.5	-1.4	-0.8	-0.1	-1.0
Schizophrenia (2018)	1.6	3.3	6.8	2.1	0.5	2.1	2.0	0.8	-0.0	1.8	2.4	-0.6	2.5	0.9	2.6	2.1	1.0	2.2	1.9	2.4
Verbal and Numeric Reasoning (VNR)	1.6	3.9	12.9	-2.4	1.9	-2.3	-0.9	0.6	0.1	-1.2	-2.5	1.9	-2.1	-0.9	-2.2	-1.1	-1.9	-2.4	-3.6	-2.4
Trunk fat mass	1.6	6.7	36.3	1.1	-6.0	0.8	-2.9	-4.0	-1.6	-1.1	1.4	-5.0	0.5	-2.9	0.3	-1.5	-0.3	1.1	2.5	1.0
Arm predicted mass (right)	1.6	8.1	49.8	0.4	-7.1	0.5	-2.6	-4.3	-0.4	-1.9	0.7	-6.0	-0.2	-3.0	-0.4	-2.3	-0.1	0.4	2.6	0.3
Illnesses of father: Heart disease	1.6	2.2	5.0	1.9	-2.1	2.0	0.8	-0.9	-0.2	0.3	1.7	-1.8	1.6	-0.1	1.1	0.8	1.2	1.7	2.2	1.7
Mother’s age at death	1.6	2.0	4.0	-1.6	0.2	-1.4	-0.7	-1.0	-1.8	-1.2	-1.5	-0.0	-1.5	-1.4	-1.5	-1.3	-2.0	-1.5	-1.9	-1.6
Arm predicted mass (left)	1.6	7.9	48.9	0.7	-7.0	0.7	-2.5	-4.2	-1.1	-1.8	0.9	-5.7	0.0	-2.7	-0.3	-2.2	0.4	0.7	3.1	0.6
Mean Putamen Volume	1.5	1.8	5.9	-0.8	-1.7	-1.2	-1.5	-1.3	-0.6	-1.4	-1.1	-2.4	-1.3	-1.6	-0.9	-1.5	-1.3	-1.0	-0.3	-1.1
Hearing difficulty/problems with background noise	1.5	2.4	4.5	-1.7	-1.4	-1.6	-1.3	-1.1	-0.4	-1.7	-1.5	-1.1	-1.6	-2.1	-1.6	-1.7	-1.9	-1.6	-1.7	-1.6
Financial difficulties in last 2 years	1.5	2.0	3.2	1.7	0.1	1.4	1.5	1.6	-0.6	1.6	1.7	0.4	1.5	1.1	1.6	1.6	1.4	1.7	1.8	1.6
Heart attack	1.5	1.9	6.1	-0.7	-2.5	-0.6	-1.7	-2.1	-1.0	-1.4	-0.5	-2.4	-0.7	-2.0	-0.8	-1.8	-0.5	-0.7	-0.1	-0.6
Arm fat percentage (right)	1.5	5.7	30.9	1.3	-5.6	1.1	-3.0	-3.6	-0.9	-0.6	1.7	-4.4	0.8	-2.3	0.6	-1.0	0.2	1.4	2.7	1.3
Arm fat-free mass (right)	1.5	7.8	48.2	0.3	-6.9	0.4	-2.7	-4.2	-0.5	-2.0	0.5	-5.8	-0.4	-3.0	-0.6	-2.4	-0.1	0.3	2.5	0.2
Hypertension (Self-reported)	1.5	4.1	17.9	-0.5	-4.2	-0.2	-2.5	-3.2	-0.0	-1.8	-0.3	-4.1	-0.9	-2.7	-0.4	-2.0	-1.5	-0.5	0.7	-0.6
High cholesterol (Self-reported)	1.5	2.7	6.9	-1.1	-2.6	-1.0	-2.0	-2.5	1.1	-1.6	-1.0	-2.4	-1.3	-2.3	-1.0	-1.7	-1.6	-1.1	-0.3	-1.2
Arm fat-free mass (left)	1.5	7.6	47.3	1.0	-6.9	1.0	-2.4	-4.0	-0.8	-1.4	1.2	-5.6	0.3	-2.4	0.0	-1.9	0.6	1.0	3.4	0.9
Impedance of whole body	1.5	7.4	43.6	-1.2	6.6	-1.2	2.8	3.7	0.5	1.2	-1.4	5.3	-0.4	1.8	-0.2	1.7	-1.7	-1.2	-3.9	-1.1
Depressed Affect (Nagel 2018)	1.4	2.9	23.6	0.1	-3.0	0.4	-0.0	-1.4	-0.1	-1.1	0.4	-4.9	0.0	-2.6	0.8	-0.7	-1.9	0.1	0.8	0.1
Rheumatoid Arthritis	1.4	1.9	2.9	1.6	0.5	1.6	1.1	1.0	-1.2	1.4	1.5	0.7	1.5	1.3	1.5	1.6	1.5	1.6	1.7	1.6
Schizophrenia (2014)	1.4	3.2	6.2	2.2	0.6	2.2	1.8	-0.1	-0.7	1.8	2.5	-0.2	2.4	0.8	2.1	1.8	1.2	2.3	1.9	2.3
Supplements: Zinc	1.4	1.5	3.2	1.2	0.1	1.6	1.1	1.1	-1.0	1.2	1.3	0.3	1.3	1.1	1.3	1.3	1.5	1.4	1.8	1.4
Hair/balding pattern: Pattern 2	1.4	1.8	5.7	1.1	2.4	1.1	2.1	1.4	0.9	1.4	1.1	1.5	1.3	1.3	1.2	1.4	0.7	1.1	0.4	1.1
Pain all over the body in last month	1.4	1.5	7.9	-0.7	-1.8	-0.8	-2.8	-1.7	-0.8	-1.0	-0.6	-1.5	-0.9	-1.3	-0.5	-1.1	-1.0	-0.7	-0.5	-0.8
Illnesses of siblings	1.4	2.0	6.2	0.8	2.5	1.0	1.6	2.4	0.7	1.3	0.6	2.3	1.0	1.8	0.7	1.5	1.4	0.7	-0.1	0.8
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	6.8	2.1	-0.3	2.0	0.5	-0.4	2.6	1.6	2.0	-0.2	1.9	1.0	1.6	1.2	1.8	2.0	2.0	2.0
Body fat percentage	1.4	5.5	26.8	1.2	-5.2	0.8	-2.8	-3.9	-1.0	-0.6	1.6	-4.5	0.8	-2.7	0.6	-1.0	-0.5	1.3	2.2	1.2
Overall health rating	1.4	3.0	13.7	1.5	-3.4	1.3	-1.1	-1.5	0.4	-0.0	1.7	-3.7	1.2	-1.5	1.5	-0.3	0.1	1.4	2.2	1.4
Leg pain on walking	1.4	1.7	9.0	-0.5	-2.0	-0.9	-1.4	-1.8	0.2	-1.3	-0.3	-3.0	-0.7	-2.0	-0.3	-1.3	-1.2	-0.5	0.4	-0.6
Arm fat percentage (left)	1.4	5.7	30.9	1.2	-5.6	0.9	-3.0	-3.7	-0.7	-0.7	1.5	-4.6	0.6	-2.6	0.5	-1.1	-0.3	1.2	2.3	1.1
Medication for cholesterol	1.4	2.1	6.6	0.8	2.6	0.8	1.6	2.0	-0.3	1.4	0.7	2.2	0.9	2.2	0.7	1.4	1.9	0.8	1.0	0.8
Osteoporosis (self-reported)	1.4	1.7	3.9	1.0	1.6	0.9	1.3	1.1	-0.8	1.5	1.0	2.0	1.0	1.9	0.8	1.2	1.9	1.0	1.4	1.0
Heart attack/myocardial infarction (self-reported)	1.4	1.8	6.7	-0.5	-2.6	-0.4	-1.6	-2.0	-0.9	-1.3	-0.3	-2.5	-0.6	-2.0	-0.7	-1.7	-0.5	-0.5	0.0	-0.4
Bipolar Disorder (2018)	1.3	2.1	5.9	1.2	2.4	1.3	1.6	2.0	-0.3	1.7	1.0	2.3	1.2	1.6	0.9	1.5	0.9	1.2	-0.0	1.0
Lung FVC	1.3	6.4	10.6	2.9	1.0	3.0	1.8	2.2	2.0	2.8	3.0	-0.3	2.9	2.2	3.1	2.7	2.0	2.9	3.3	2.9
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	2.7	-1.2	-0.8	-1.3	-0.4	-1.5	-1.6	-1.5	-1.3	-1.0	-1.2	-1.6	-1.5	-1.6	-1.2	-1.3	-1.1	-1.2
Multivitamins +/- minerals	1.3	1.7	3.3	1.6	0.4	1.6	1.1	1.2	0.0	1.5	1.6	-0.2	1.7	0.6	1.8	1.4	0.6	1.6	1.3	1.6
Leg predicted mass (left)	1.3	6.7	45.0	0.3	-6.7	0.6	-2.5	-3.7	-1.2	-1.9	0.5	-4.8	-0.5	-2.3	-0.8	-2.4	0.7	0.3	2.8	0.2
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	5.9	-1.2	-1.3	-1.3	-0.9	-1.3	0.7	-1.6	-1.2	-2.4	-1.3	-2.1	-0.9	-1.4	-2.0	-1.3	-0.9	-1.3
Qualifications: College or University degree	1.3	4.2	23.4	-0.1	4.5	0.0	1.1	3.4	0.4	1.5	-0.5	4.8	0.1	2.4	0.1	1.4	0.4	-0.3	-2.0	-0.2
Age at last live birth	1.3	2.0	5.6	0.9	2.4	0.9	2.0	1.6	0.4	1.6	0.8	2.3	1.1	1.8	0.9	1.4	1.3	0.9	0.2	0.9
Medication: Aspirin	1.3	1.7	9.9	0.2	-3.1	0.4	-1.4	-1.8	-0.5	-0.6	0.4	-2.5	0.1	-1.7	-0.0	-1.1	0.1	0.2	1.1	0.3
Basal metabolic rate	1.3	7.4	48.4	0.6	-7.0	0.8	-2.4	-4.0	-0.9	-1.8	0.8	-5.4	-0.2	-2.5	-0.4	-2.3	0.5	0.6	3.0	0.5
Vascular/heart problems diagnosed by doctor	1.3	3.6	16.9	0.1	4.1	-0.3	2.3	2.8	-0.1	1.4	-0.2	4.0	0.5	2.6	0.2	1.8	1.2	0.1	-0.8	0.2
Intelligence (Savage-Jansen 2018)	1.2	3.7	14.0	-1.7	3.7	-2.0	-0.1	1.7	1.2	-0.1	-2.0	3.0	-1.4	0.5	-1.4	-0.1	-1.5	-1.8	-3.5	-1.8
Schizophrenia vs Biploar Disorder	1.2	1.6	7.0	1.1	-2.1	1.0	-0.3	-1.5	-1.0	0.0	1.3	-2.6	0.9	-1.0	1.0	0.3	0.3	1.0	1.7	1.1
Neuroticism	1.2	2.9	22.7	0.1	-3.2	0.3	-0.2	-1.6	0.3	-1.2	0.5	-4.8	0.1	-2.4	0.9	-0.5	-2.1	0.2	1.0	0.2
Frequency of depressed mood in last 2 weeks	1.2	1.7	14.4	0.2	-1.8	-0.0	-0.6	-1.2	0.4	-0.6	0.6	-3.8	0.4	-1.9	1.1	-0.1	-1.7	0.2	0.5	0.4
Leg fat-free mass (left)	1.2	6.5	44.1	0.4	-6.6	0.7	-2.5	-3.6	-1.2	-1.8	0.5	-4.7	-0.4	-2.2	-0.7	-2.3	0.8	0.4	2.9	0.3
Serious illness, injury or assault to yourself	1.2	1.5	3.5	-0.9	-1.9	-0.8	-1.1	-1.4	0.1	-1.3	-1.0	-1.5	-1.1	-1.6	-1.1	-1.7	-1.0	-1.0	-0.8	-1.0
Medication: Levothyroxine sodium	1.2	2.1	4.0	1.8	-0.8	1.7	0.0	-0.6	2.0	1.3	1.8	-0.1	1.6	1.0	1.2	1.0	2.0	1.7	1.9	1.8
Time employed in main current job	1.2	1.3	5.4	-0.9	-2.3	-0.5	-1.0	-1.0	-0.9	-1.4	-0.9	-1.6	-0.8	-1.6	-1.0	-1.4	-1.0	-0.9	-0.3	-0.8
Noisy workplace	1.2	1.4	3.9	1.5	-1.8	1.3	-0.2	0.4	0.9	0.5	1.4	-1.7	1.0	0.0	1.1	0.5	1.1	1.4	2.0	1.3
Medication for pain relief, constipation, heartburn	1.2	2.1	12.5	-0.6	3.5	-0.8	0.2	1.0	1.3	0.4	-1.0	3.1	-0.7	2.0	-0.6	0.9	0.5	-0.7	-1.3	-0.8
Whole body fat-free mass	1.2	6.6	44.0	0.3	-6.6	0.6	-2.1	-3.7	-0.9	-1.9	0.5	-5.0	-0.4	-2.3	-0.7	-2.3	0.6	0.3	2.8	0.2
Leg fat-free mass (right)	1.2	6.2	41.7	0.2	-6.5	0.4	-2.3	-3.4	-1.4	-2.0	0.3	-4.5	-0.6	-2.2	-0.9	-2.5	0.6	0.1	2.6	0.0
Loneliness, isolation	1.2	1.6	14.0	0.7	-2.0	0.7	0.3	-0.7	0.5	-0.5	0.8	-3.7	0.5	-1.4	1.0	-0.2	-1.1	0.6	1.2	0.6
Mineral and other dietary supplements	1.2	1.6	2.6	-1.3	-1.1	-1.5	-1.6	-1.5	-0.9	-1.5	-1.4	-1.0	-1.4	-0.9	-1.2	-1.5	-0.9	-1.4	-0.9	-1.3
Whole body water mass	1.2	6.6	44.0	0.3	-6.6	0.6	-2.1	-3.8	-0.8	-1.9	0.5	-5.0	-0.4	-2.4	-0.7	-2.4	0.6	0.3	2.8	0.2
Wears glasses or contact lenses	1.2	1.4	3.9	0.9	1.6	1.0	2.0	0.5	-0.5	1.2	0.6	1.1	0.7	1.9	1.0	1.2	1.5	0.7	1.4	0.8
Depression (Nagel 2018)	1.1	1.7	9.5	1.2	-1.3	0.8	-0.2	-1.0	0.2	0.5	1.4	-3.1	1.2	-1.1	1.9	0.8	-0.9	1.2	1.0	1.3
Worry (Nagel 2018)	1.1	2.4	9.9	-1.1	-2.5	-0.8	0.1	-1.4	0.3	-1.6	-1.1	-3.1	-1.1	-2.4	-0.6	-1.3	-2.2	-1.0	-0.4	-1.1
Number of treatments/medications taken	1.1	2.0	7.5	-0.6	-2.7	-0.4	-0.5	-2.3	-1.7	-1.4	-0.3	-2.5	-0.5	-2.1	-0.6	-1.7	-1.1	-0.5	0.3	-0.5
Hearing difficulty/problems: Yes	1.1	1.6	3.1	-1.6	-0.5	-1.5	-1.0	-0.9	-0.5	-1.4	-1.5	0.0	-1.5	-1.0	-1.4	-1.3	-1.3	-1.5	-1.8	-1.6
Impedance of leg (right)	1.1	5.1	34.0	-1.0	5.8	-1.1	2.0	2.3	1.5	1.3	-0.9	3.8	0.0	1.1	0.4	1.7	-2.1	-0.9	-3.5	-0.7
Trunk fat percentage	1.1	4.3	22.2	1.1	-4.7	0.8	-2.5	-3.3	-1.4	-0.6	1.4	-3.9	0.6	-2.4	0.4	-1.0	-0.4	1.1	1.9	1.0
High blood pressure	1.1	3.1	14.7	-0.1	-3.8	0.1	-2.3	-2.7	0.2	-1.4	0.1	-3.6	-0.6	-2.3	-0.2	-1.7	-1.1	-0.1	0.8	-0.3
Impedance of leg (left)	1.1	5.3	35.8	-0.8	6.0	-1.0	2.4	2.8	1.3	1.4	-0.7	3.6	0.3	1.1	0.6	2.0	-2.1	-0.7	-3.4	-0.5
Fluid intelligence score	1.1	2.3	11.5	-1.1	3.4	-1.1	0.2	1.5	-0.5	0.0	-1.4	2.9	-0.8	0.6	-0.9	0.1	-1.1	-1.4	-2.5	-1.2
Neuroticism score	1.1	2.2	17.1	-0.1	-2.5	0.3	0.6	-1.1	1.0	-1.2	0.1	-4.1	-0.2	-2.2	0.7	-0.4	-2.1	-0.1	0.6	-0.2
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.0	-1.3	-0.5	-1.3	-1.3	-0.3	-0.8	-1.3	-1.4	-1.0	-1.4	-1.0	-0.8	-0.8	-1.3	-1.4	-0.5	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	3.6	-1.6	-1.3	-1.4	-0.5	-0.4	0.1	-1.7	-1.5	-0.7	-1.4	-1.4	-1.5	-1.9	-1.3	-1.5	-1.3	-1.4
Chest pain or discomfort	1.1	1.5	4.4	-0.8	-1.9	-1.0	-1.3	-1.6	-1.1	-1.1	-0.6	-2.1	-0.7	-1.8	-0.6	-1.4	-1.3	-0.8	-0.5	-0.7
Leg predicted mass (right)	1.1	5.9	39.9	0.3	-6.3	0.5	-2.2	-3.3	-1.4	-1.9	0.3	-4.5	-0.5	-2.1	-0.8	-2.4	0.7	0.2	2.6	0.1
Irritability	1.1	1.8	6.8	-0.7	-1.7	-0.8	0.1	-2.2	-0.6	-1.1	-0.6	-2.6	-0.7	-2.0	0.1	-0.4	-2.6	-0.8	-0.8	-0.8
Age at First Birth	1.0	1.5	3.3	-1.7	0.7	-1.8	-0.6	0.3	0.2	-1.1	-1.7	0.7	-1.2	-0.6	-1.2	-0.6	-1.5	-1.6	-1.8	-1.5
Triglycerides	1.0	1.6	2.7	-1.4	-0.4	-1.6	-1.6	-1.0	-1.0	-1.4	-1.5	-0.0	-1.5	-0.9	-1.4	-1.4	-0.8	-1.5	-1.3	-1.4
Chronotype (morning person)	1.0	2.3	11.2	-0.5	3.2	-0.1	2.6	1.4	0.1	0.9	-0.6	3.3	-0.3	2.0	-0.1	1.1	0.3	-0.4	-1.1	-0.5
Medication: Co-codamol	1.0	1.2	4.4	-0.9	-1.5	-0.9	-0.8	-1.1	-2.1	-1.1	-0.6	-1.4	-0.6	-1.4	-0.4	-1.0	-1.4	-0.8	0.0	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	8.5	0.9	-1.4	1.0	-0.6	-0.9	0.9	0.2	1.2	-2.9	1.0	-0.8	1.5	0.3	-0.4	1.0	1.1	1.0
Medication: Simvastatin	1.0	1.5	5.0	-0.8	-2.2	-0.7	-1.2	-2.2	0.1	-1.2	-0.8	-1.4	-1.1	-1.5	-1.1	-1.6	-0.6	-0.8	0.2	-0.9
Trunk fat-free mass	1.0	5.8	38.3	0.4	-6.2	0.7	-1.7	-3.5	-0.6	-1.7	0.6	-4.8	-0.2	-2.1	-0.4	-2.1	0.6	0.4	2.8	0.3
Prospective memory result	1.0	1.3	4.7	1.2	-1.1	1.1	-0.0	0.6	2.2	0.6	1.3	-1.1	1.0	-0.0	1.2	0.7	0.9	1.2	1.7	1.2
Trunk predicted mass	1.0	5.8	37.9	0.3	-6.2	0.6	-1.8	-3.5	-0.6	-1.7	0.5	-4.8	-0.3	-2.2	-0.5	-2.1	0.5	0.3	2.7	0.2
Osteoarthritis (self-reported)	1.0	1.3	2.6	-0.8	-1.5	-1.0	-1.6	-0.8	-1.6	-1.2	-0.6	-1.5	-0.8	-1.5	-0.5	-1.3	-1.4	-0.8	-0.5	-0.8
Medication: Aspirin	1.0	1.3	7.8	0.6	-2.8	0.8	-1.2	-1.2	-0.8	-0.1	0.9	-2.0	0.5	-1.3	0.3	-0.8	0.4	0.7	1.3	0.7
Number of self-reported non-cancer illnesses	1.0	1.8	5.5	-0.8	-2.3	-0.6	-0.9	-2.2	-0.6	-1.4	-0.5	-2.4	-0.9	-1.8	-0.6	-1.7	-1.3	-0.7	-0.4	-0.7
Alzheimer’s Disease (in father)	0.9	0.9	6.6	-0.3	-2.6	0.1	-0.3	-0.6	-1.4	-1.1	-0.3	-1.8	-0.5	-0.7	-0.4	-1.0	-0.0	-0.3	0.7	-0.3
Angina	0.9	1.1	5.1	-0.4	-2.3	-0.5	-1.2	-1.8	-0.6	-0.6	-0.2	-2.0	-0.3	-1.3	-0.2	-1.2	-0.6	-0.3	0.7	-0.2
High blood pressure (mother)	0.9	1.3	2.2	-1.3	-0.9	-1.3	-0.6	-0.8	-0.3	-1.4	-1.4	-0.7	-1.5	-0.8	-1.4	-1.4	-0.8	-1.4	-0.7	-1.4
Alcohol usually taken with meals	0.9	1.5	7.5	-1.0	2.7	-0.7	1.0	-0.0	0.6	0.5	-1.1	2.4	-0.7	0.6	-0.7	0.3	-1.0	-1.0	-1.9	-1.0
Alcohol intake versus 10 years previously	0.9	1.4	8.7	0.3	-1.8	0.0	-0.8	-1.0	-3.0	-0.6	0.5	-2.3	0.3	-1.0	0.7	-0.1	-0.7	0.3	1.2	0.3
Number of live births	0.9	1.3	6.5	1.2	-1.4	1.4	-0.4	0.1	0.3	0.4	1.3	-0.9	0.9	0.6	0.7	0.5	1.8	1.2	2.5	1.1
Forced expiratory volume in 1-second (FEV1)	0.9	3.0	11.3	1.0	2.2	1.6	3.2	3.4	1.1	1.9	1.0	1.5	1.1	1.9	1.5	1.9	0.6	1.0	0.7	1.0
Pulse wave Arterial Stiffness index	0.9	1.1	4.1	-0.8	-1.1	-0.8	-2.0	-1.0	-0.6	-0.9	-0.6	-1.5	-0.6	-1.4	-0.5	-1.2	-1.2	-0.7	-0.5	-0.7
Birth weight of first child	0.9	1.7	4.5	1.2	1.0	1.3	2.1	1.3	1.6	1.1	1.0	1.1	1.2	1.6	1.1	1.5	1.3	1.1	0.9	1.1
Birth weight	0.9	1.9	5.2	-1.5	-1.1	-1.1	-1.4	-0.9	-2.3	-1.3	-1.5	0.3	-1.3	-0.7	-1.8	-1.9	-0.2	-1.5	-1.6	-1.3
Commuting to job workplace: Car/motor vehicle	0.9	1.1	2.4	-1.3	1.2	-1.6	0.1	-0.7	0.4	-0.6	-1.4	1.2	-1.1	0.1	-1.3	-0.5	-0.2	-1.3	-1.3	-1.2
Illnesses of father: None of the above (group 1)	0.9	1.1	2.9	-1.3	1.7	-1.5	-0.6	0.3	-0.3	-0.2	-1.2	1.7	-1.0	0.4	-0.7	-0.4	-0.8	-1.2	-1.3	-1.1
Ever taken oral contraceptive pill	0.9	1.0	4.8	-1.1	2.2	-1.2	0.3	0.2	0.3	-0.0	-1.0	0.7	-0.7	-0.1	-0.3	-0.1	-1.4	-1.1	-1.9	-1.0
Medication: Blood pressure	0.9	1.7	7.7	-0.1	-2.8	0.0	-1.4	-2.5	0.1	-1.2	0.1	-2.3	-0.2	-1.9	-0.2	-1.1	-1.0	-0.1	-0.1	-0.1
Pain type(s) experienced in last month: Hip pain	0.9	1.1	5.8	-0.1	-1.8	0.2	-0.9	-0.9	-2.4	-0.6	0.1	-2.0	-0.1	-1.5	-0.2	-1.1	-0.7	-0.0	0.2	-0.0
Coronary Artery Disease (CAD)	0.8	1.0	4.2	0.7	-2.0	0.7	-0.8	-1.0	-1.3	-0.3	0.8	-1.8	0.5	-0.7	0.4	-0.2	0.8	0.7	1.5	0.7
Neuroticism (2016)	0.8	1.1	4.8	-0.7	-1.9	-0.1	0.1	-0.7	-1.3	-1.2	-0.6	-2.2	-0.7	-1.4	-0.2	-0.9	-1.2	-0.7	-0.2	-0.7
Ulcerative Colitis	0.8	1.2	4.4	1.1	-1.5	1.1	-0.6	0.6	0.8	0.4	1.1	-0.9	1.0	0.5	1.1	0.8	1.3	1.1	2.1	1.1
Relative age of first facial hair	0.8	1.7	3.5	-1.4	-0.8	-1.6	-1.5	-0.6	-0.6	-1.7	-1.6	-1.1	-1.9	-0.7	-1.4	-1.1	-0.8	-1.5	-0.7	-1.7
Medication: Metformin	0.8	1.1	4.1	1.1	-1.7	1.3	-0.0	-0.4	-0.5	0.6	1.2	-0.4	0.9	0.8	0.9	0.3	1.5	1.1	2.0	1.2
Diabetes (mother)	0.8	1.1	2.3	1.1	0.0	1.5	1.5	0.9	1.5	1.0	0.9	0.6	0.8	1.0	1.0	0.9	1.2	1.0	0.7	0.9
Severe depression (siblings)	0.8	0.9	3.3	0.9	-1.8	1.1	0.2	0.3	0.7	0.3	1.0	-0.9	0.7	0.0	0.8	0.5	1.0	1.0	1.8	0.9
Hayfever, allergic rhinitis or eczema	0.8	1.8	9.2	0.1	2.5	0.1	2.1	1.5	-1.5	0.8	-0.3	3.0	0.2	1.9	-0.1	0.6	1.1	-0.1	-0.4	0.1
Had menopause	0.8	1.0	4.0	1.2	-0.6	1.3	0.5	-0.3	-0.9	0.6	1.2	-0.3	1.1	0.7	0.8	0.4	1.4	1.1	2.0	1.2
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	3.5	0.9	0.7	1.2	1.0	1.9	1.1	0.9	1.0	-0.1	0.9	1.0	1.0	0.7	1.0	1.0	0.9	1.0
Worrier / anxious feelings	0.8	1.5	3.9	-1.2	-1.5	-1.0	-0.5	-1.3	-0.8	-1.4	-1.2	-1.5	-1.4	-1.4	-0.6	-1.0	-2.0	-1.2	-1.0	-1.3
Qualifications: A levels/AS levels or equivalent	0.8	1.7	8.0	-0.7	2.8	-0.4	1.1	1.7	1.5	0.4	-0.9	2.7	-0.4	1.0	-0.7	0.2	0.0	-0.7	-1.6	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.7	-0.8	-1.6	-0.9	-0.6	-0.8	-0.3	-1.1	-0.6	-1.7	-0.7	-1.5	-0.8	-1.5	-1.3	-0.8	-0.5	-0.7
Medication: Cholesterol lowering	0.8	1.2	4.2	-0.7	-2.0	-0.6	-0.8	-2.0	0.5	-1.2	-0.8	-1.3	-1.0	-1.3	-1.1	-1.4	-0.2	-0.8	0.3	-0.9
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	4.0	0.8	2.0	0.9	0.9	1.7	0.8	1.0	0.5	1.7	0.6	1.0	0.5	1.2	0.8	0.6	0.1	0.6
Gout (self-reported)	0.8	1.1	2.7	1.2	-0.7	0.9	-1.0	0.3	1.5	0.8	1.1	0.0	0.8	1.1	1.1	1.0	1.1	1.2	1.6	1.0
Exposure to tobacco smoke outside home	0.8	1.1	4.7	-0.7	-1.3	-0.8	-0.2	-2.2	-1.3	-1.0	-0.5	-1.5	-0.7	-1.6	-0.7	-0.9	-0.8	-0.6	-0.2	-0.6
Wheeze or whistling in the chest in last year	0.8	1.5	6.5	0.5	-2.4	0.4	-2.5	-1.8	-0.3	-0.2	0.8	-1.8	0.5	-0.6	0.3	-0.3	0.9	0.6	1.6	0.7
Age at first live birth	0.8	1.4	6.5	-1.0	2.6	-0.9	1.4	0.9	0.4	0.2	-1.1	2.2	-0.6	0.7	-0.5	0.2	-0.7	-1.0	-1.7	-0.9
Pulse wave peak to peak time	0.8	1.0	4.7	0.7	1.0	0.8	2.2	1.0	0.5	0.9	0.5	1.6	0.4	1.3	0.4	1.0	1.1	0.6	0.4	0.5
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.1	1.2	0.1	1.4	0.7	0.0	-0.3	0.9	1.3	-0.1	1.3	0.6	1.5	1.1	0.4	1.2	1.1	1.2
Suffer from ‘nerves’	0.8	1.2	6.7	-0.2	-1.9	0.2	0.7	-0.5	2.0	-0.9	-0.1	-2.6	-0.3	-1.5	0.1	-0.7	-0.9	-0.2	0.3	-0.2
Smoking status: Current	0.8	1.3	5.9	1.1	-1.9	0.8	-0.8	-0.0	0.3	0.2	1.4	-2.4	1.1	-0.6	1.2	0.1	0.2	1.1	1.4	1.2
Pack years of smoking	0.8	1.2	2.8	0.9	-1.3	1.0	-0.3	-1.5	-1.1	0.5	1.3	-1.6	0.9	0.0	1.0	0.6	0.9	1.3	1.7	1.1
Primary Biliary Cirrhosis	0.7	1.0	2.0	-1.2	0.9	-1.3	-0.0	0.1	-0.4	-0.5	-1.3	1.4	-1.1	0.0	-1.1	-0.7	-0.7	-1.3	-1.3	-1.3
Hypothyroidism (self reported)	0.7	1.6	3.8	1.6	-1.2	1.6	0.3	-0.6	1.9	0.9	1.5	-0.9	1.3	0.4	1.1	0.5	1.4	1.5	1.9	1.5
Respiratory disease	0.7	1.6	3.1	-1.7	0.6	-1.4	-0.7	-0.5	-0.8	-1.3	-1.6	0.3	-1.6	-0.8	-1.4	-1.1	-1.4	-1.5	-1.8	-1.6
Sensitivity / hurt feelings	0.7	1.1	7.0	0.5	-1.8	0.7	0.1	-0.8	1.7	-0.3	0.7	-2.6	0.5	-0.9	1.0	0.2	-0.5	0.5	1.2	0.6
Vitamin and mineral supplements	0.7	0.9	1.6	-1.0	-0.5	-1.3	-1.0	-1.1	0.5	-1.1	-1.1	-0.3	-1.1	-0.6	-1.2	-1.0	-0.5	-1.1	-0.7	-1.1
Diabetes (father)	0.7	0.9	3.2	-0.3	-0.7	-0.6	-1.2	-0.4	0.5	-0.7	-0.4	-1.4	-0.7	-1.8	-0.3	-0.5	-1.8	-0.5	-1.4	-0.6
Pack years adult smoking proportion	0.7	1.1	2.4	1.1	-0.8	1.0	-0.1	-1.1	-0.6	0.8	1.4	-1.5	1.1	0.2	1.3	0.9	0.7	1.4	1.5	1.2
Hand grip strength (right)	0.7	2.0	5.2	1.6	-1.7	1.5	0.0	-0.5	1.7	0.6	1.7	-1.4	1.5	0.5	1.2	0.8	1.8	1.6	2.3	1.6
Current tobacco smoking	0.7	1.1	4.7	1.0	-1.9	0.6	-0.8	-0.2	0.6	0.2	1.2	-2.2	1.0	-0.4	1.1	0.2	0.4	1.0	1.4	1.1
Medication: Atenolol	0.7	0.9	2.5	1.0	-1.6	0.7	0.0	-1.2	0.9	0.2	1.1	-1.5	0.7	-0.2	0.7	-0.1	0.7	1.0	1.2	0.9
Mouth/teeth dental problems	0.7	1.1	2.8	-1.0	-0.8	-0.9	-0.7	-0.9	-0.4	-1.3	-1.0	-1.4	-1.0	-1.2	-0.8	-1.2	-1.7	-1.1	-0.9	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	9.8	0.4	2.3	1.1	3.0	3.1	1.4	1.3	0.4	1.8	0.5	1.5	0.6	1.2	0.3	0.4	-0.2	0.4
Tense / ‘highly strung’	0.7	1.2	4.0	-0.8	-1.2	-0.7	0.7	-1.2	-0.7	-1.0	-0.7	-1.9	-0.6	-1.7	-0.2	-0.5	-2.0	-0.8	-0.9	-0.8
Loud music exposure frequency	0.7	0.7	3.5	0.8	-1.6	0.8	0.0	-0.1	0.7	-0.0	0.9	-1.9	0.7	-0.5	0.6	-0.1	0.4	0.8	1.0	0.8
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	2.3	-1.3	0.6	-1.2	0.6	0.9	-0.0	-0.9	-1.5	1.1	-1.1	-0.3	-1.5	-1.0	-0.7	-1.4	-1.5	-1.3
Comparative body size at age 10	0.7	1.9	5.5	1.5	-2.0	1.4	-0.7	-1.2	1.2	0.5	1.5	-2.1	1.2	-0.7	1.1	0.4	1.0	1.4	2.4	1.4
Neck or shoulder pain in last month	0.7	1.0	5.9	0.7	-0.8	0.8	0.6	-1.4	-2.4	0.3	0.9	-1.6	0.9	-0.9	0.8	0.2	-0.5	0.7	0.5	0.8
Medication: Ibuprofen	0.7	0.8	4.0	-0.5	-1.7	-0.6	-0.5	-0.5	-0.0	-0.8	-0.2	-2.0	-0.2	-1.5	-0.4	-1.1	-1.0	-0.4	-0.1	-0.2
Supplements: Vitamin C	0.7	0.8	1.7	0.8	-0.4	1.2	0.8	0.2	-1.3	0.9	1.0	0.1	0.7	0.8	0.8	0.8	1.2	0.9	1.3	0.9
Illnesses of siblings: Diabetes	0.7	0.8	3.4	-0.3	-1.4	-0.7	-0.8	-1.2	-0.4	-0.7	-0.3	-1.8	-0.3	-1.4	0.1	-0.9	-1.5	-0.4	-0.3	-0.4
Average weekly champagne plus white wine intake	0.7	1.0	6.9	-0.0	2.1	-0.2	0.5	0.2	0.9	0.7	-0.3	2.6	-0.0	1.5	-0.3	1.0	0.8	-0.1	-0.4	-0.2
Miserableness	0.7	1.2	9.6	0.2	-2.0	0.7	-0.2	-0.4	0.4	-0.5	0.5	-3.1	-0.0	-1.8	0.6	-0.2	-1.3	0.3	0.6	0.1
Cholesterol lowering medication	0.7	1.0	3.5	-0.4	-1.9	-0.3	-0.9	-0.9	0.0	-0.7	-0.3	-1.8	-0.5	-1.8	-0.4	-1.2	-1.5	-0.4	-0.6	-0.4
Ulcerative Colitis (UC)	0.6	1.1	3.7	1.2	-0.8	0.9	-0.2	0.7	0.8	0.7	1.2	-0.6	1.2	0.7	1.1	0.7	1.4	1.2	1.9	1.3
Bipolar Disorder (2011)	0.6	0.6	2.6	0.0	1.4	0.4	1.1	1.2	-0.1	0.4	0.0	1.6	0.1	1.0	0.1	0.7	0.2	-0.0	-0.8	-0.1
Hand grip strength (left)	0.6	1.6	4.3	1.3	-1.0	1.3	0.8	-0.3	1.8	0.6	1.4	-0.6	1.3	1.2	1.0	0.9	2.1	1.4	1.8	1.5
Systolic blood pressure, automated reading	0.6	1.7	8.3	-0.2	-2.9	-0.3	-1.1	-2.3	-0.8	-1.4	-0.2	-2.3	-0.5	-1.5	-0.7	-1.4	-0.3	-0.4	0.5	-0.3
Chronic bronchitis/emphysema (father)	0.6	0.7	1.3	-1.1	-0.3	-0.7	0.3	0.3	-0.4	-0.8	-0.9	-0.4	-0.9	-1.0	-1.1	-1.2	-0.6	-1.0	-1.0	-0.9
Qualifications: None of the above	0.6	1.4	5.9	0.6	-2.4	0.7	-1.0	-2.0	-1.6	-0.1	0.9	-1.7	0.4	-0.5	0.4	-0.3	1.0	0.9	1.7	0.8
Happiness	0.6	0.8	5.9	0.2	-1.6	0.3	-1.0	-0.6	-0.2	-0.5	0.3	-2.4	0.2	-1.1	0.1	-0.5	-0.2	0.2	0.9	0.2
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	4.5	0.1	2.1	0.1	0.9	1.7	-0.1	0.9	0.1	1.7	0.4	1.0	0.4	1.1	-0.0	0.1	-1.0	0.2
Eye problems/disorders: None of the above	0.6	0.6	3.0	-0.5	-0.8	-0.4	-0.7	-0.8	-1.7	-0.5	-0.4	-1.2	-0.6	-1.2	-0.5	-0.7	-0.9	-0.5	-0.1	-0.6
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	4.3	0.5	1.6	0.1	0.0	-0.4	0.3	0.8	0.4	2.1	0.5	1.4	0.2	0.6	0.8	0.4	-0.1	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.5	-1.5	-0.0	-0.7	1.0	1.4	0.5	-0.9	-1.6	0.7	-1.5	-0.2	-1.4	-0.9	-0.5	-1.4	-1.1	-1.5
Age started oral contraceptive pill	0.6	0.8	2.9	-0.8	-1.0	-0.7	-0.2	-1.2	-1.7	-0.8	-0.6	-0.6	-0.8	-1.0	-0.7	-0.7	-1.1	-0.6	-0.6	-0.7
Myopia	0.6	0.9	3.6	-0.2	1.9	-0.0	1.2	1.8	0.1	0.5	-0.5	1.9	-0.3	0.9	-0.3	0.7	0.1	-0.3	-1.0	-0.4
Pain experienced in last month	0.6	1.0	4.4	-0.1	1.7	-0.3	0.6	1.4	2.1	0.4	-0.2	1.9	-0.1	1.3	0.0	0.8	0.6	-0.1	-0.4	-0.2
Supplements: Calcium	0.6	0.6	1.2	0.8	1.0	0.8	1.1	1.0	-0.2	0.8	0.8	0.5	0.9	0.8	0.7	0.8	0.7	0.8	0.5	0.8
Heart disease (siblings)	0.6	0.7	3.5	-0.2	-1.9	-0.1	-0.5	-1.6	-1.4	-0.6	0.1	-1.4	-0.4	-0.7	-0.5	-0.5	0.2	0.1	0.6	-0.1
Lupus	0.5	0.8	3.2	-1.0	-0.0	-0.7	0.4	-1.3	-1.8	-1.0	-1.0	0.1	-1.0	0.0	-0.8	-0.6	-0.5	-1.1	-0.2	-1.1
Type 2 Diabetes (T2D) (2012)	0.5	0.5	2.3	0.2	1.5	0.2	1.0	0.9	0.1	0.7	0.3	1.2	0.4	1.1	0.8	0.9	-0.1	0.2	-0.4	0.3
Smoking Status	0.5	1.2	4.7	1.2	-2.0	0.6	-0.4	-0.8	0.4	0.2	1.4	-2.2	1.1	-0.6	1.2	0.2	0.0	1.1	1.1	1.1
Average weekly spirits intake	0.5	0.6	3.1	0.7	-0.1	0.7	0.5	-0.4	1.8	0.7	0.8	0.1	0.6	0.7	0.6	0.6	0.9	0.8	0.5	0.7
Average weekly fortified wine intake	0.5	0.6	5.4	0.3	0.3	0.8	0.9	0.6	2.3	0.5	0.3	-0.2	0.1	0.7	0.7	0.8	0.3	0.3	0.5	0.2
Age when periods started (menarche)	0.5	1.1	4.9	0.4	1.5	0.7	1.8	0.9	-0.6	1.0	0.4	2.2	0.5	1.7	0.2	0.8	1.2	0.5	0.5	0.5
Had other major operations	0.5	0.6	1.3	1.0	0.0	0.9	0.1	-0.3	-1.1	0.7	1.0	-0.4	0.8	0.3	1.1	0.7	0.1	1.0	1.0	0.9
Forced vital capacity (FVC)	0.5	1.7	5.2	1.0	0.9	1.5	2.2	2.3	0.6	1.4	1.1	0.4	1.1	1.5	1.3	1.2	0.8	1.0	1.3	1.1
Peak expiratory flow (PEF)	0.5	1.2	5.5	-0.9	1.1	-0.2	2.1	1.4	2.3	0.1	-0.7	0.3	-0.5	-0.1	-0.0	0.2	-1.7	-0.8	-1.5	-0.7
Number of children fathered	0.5	0.5	1.7	0.7	0.8	0.5	1.3	0.6	-0.3	0.8	0.7	0.7	0.7	0.8	0.7	0.6	0.8	0.8	0.4	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.0	-0.5	-1.4	-0.4	-0.4	-0.3	-0.4	-1.0	-0.6	-0.9	-0.8	-1.0	-1.1	-1.2	0.1	-0.6	-0.2	-0.6
Angina (self-reported)	0.5	0.7	3.8	-0.0	-1.9	-0.1	-0.7	-1.3	-0.3	-0.3	0.1	-1.7	0.0	-0.8	0.1	-0.8	-0.1	0.0	1.0	0.1
Alcohol intake frequency.	0.5	1.2	5.4	0.3	-2.3	-0.3	-1.4	-1.6	-0.2	-0.7	0.3	-2.1	0.1	-1.5	0.0	-0.5	-0.3	0.3	1.4	0.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.2	0.1	0.8	0.2	0.3	1.6	-0.3	0.4	-0.0	1.8	0.1	1.0	-0.4	0.6	1.4	0.1	0.0	0.1
Back pain experienced in last month	0.5	0.8	5.0	-0.1	-2.2	0.2	-0.4	-0.8	-0.9	-0.9	0.1	-1.8	-0.0	-1.0	-0.5	-0.9	0.0	-0.1	0.6	0.0
Hearing aid user	0.5	0.5	2.9	0.4	-0.0	0.5	0.6	0.6	1.7	0.3	0.5	0.5	0.7	0.9	0.5	0.5	1.2	0.5	0.8	0.6
Financial situation satisfaction	0.5	0.6	3.9	0.3	-2.0	0.4	-0.6	0.5	0.4	-0.3	0.3	-1.7	-0.1	-0.5	0.0	-0.3	0.4	0.2	1.2	0.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	5.5	-0.7	-0.1	-0.6	-0.0	-0.4	-2.4	-0.7	-0.7	-0.1	-0.7	-0.1	-0.8	-0.7	-0.2	-0.6	-0.0	-0.6
Eye problems/disorders: Glaucoma	0.5	0.6	3.9	-0.4	1.3	-0.1	0.8	0.1	1.0	0.1	-0.3	2.0	0.2	0.7	-0.5	-0.3	0.8	-0.3	-0.8	0.0
Ever smoked	0.5	0.8	1.4	1.1	0.6	0.5	0.9	0.1	0.5	0.9	1.0	0.4	1.0	1.2	1.2	1.0	1.1	1.0	1.2	1.0
Average weekly beer plus cider intake	0.5	0.7	2.3	1.0	0.1	0.9	0.2	1.5	-0.1	0.6	1.0	-0.1	0.8	0.7	0.9	0.6	1.0	0.9	1.0	0.9
Unable to work because of sickness or disability	0.5	0.6	1.3	0.9	-0.8	1.1	0.1	0.8	0.4	0.7	1.0	-1.1	0.8	-0.4	1.1	0.4	-0.5	0.9	0.7	0.8
Blood Platelet Count	0.4	4.3	8.8	1.6	3.0	1.7	2.6	2.2	1.2	2.7	1.8	2.8	1.9	2.3	2.0	2.0	1.7	1.8	0.8	1.8
Townsend deprivation index at recruitment	0.4	0.6	3.3	0.3	-1.0	0.1	-1.5	-0.5	0.3	-0.3	0.5	-1.8	0.4	-1.5	0.1	-0.3	-0.6	0.4	-0.1	0.4
Stomach or abdominal pain in last month	0.4	0.5	2.9	0.7	0.4	0.7	1.5	-0.6	-1.7	0.3	0.6	0.0	0.5	0.1	0.3	0.2	0.5	0.6	0.7	0.6
Supplements: Glucosamine	0.4	0.6	2.9	0.2	1.2	0.7	1.7	1.3	-0.2	0.8	0.3	1.1	0.4	0.5	0.2	0.3	0.3	0.3	-0.1	0.4
Allergy	0.4	0.9	2.7	0.9	-1.1	0.7	-0.7	-0.1	1.7	0.5	1.0	-1.5	0.9	-0.6	1.0	0.7	-0.2	0.9	1.0	0.9
Medication: Lansoprazole	0.4	0.5	2.7	0.1	1.3	0.1	0.6	0.5	-1.2	0.7	0.2	1.6	0.6	0.3	0.1	0.1	-0.2	0.2	-1.0	0.3
Lung cancer (father)	0.4	0.5	4.4	-0.5	-0.1	-0.6	0.3	-0.5	-2.1	-0.6	-0.6	0.1	-0.6	-0.1	-0.4	-0.5	-0.9	-0.6	-0.4	-0.6
Length of working week for main job	0.4	0.5	3.4	0.1	-1.2	-0.3	-0.7	-0.6	0.2	-0.2	0.2	-1.9	0.3	-1.0	0.4	-0.3	-0.9	0.1	0.2	0.2
Glaucoma (self-reported)	0.4	0.5	1.6	-0.7	0.9	-0.3	1.3	-0.7	0.2	-0.2	-0.6	1.2	-0.2	-0.0	-0.9	-0.7	0.1	-0.6	-0.8	-0.3
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.4	0.6	-0.6	0.4	-1.1	-0.4	-1.0	0.5	0.7	-0.3	0.5	0.5	0.8	0.4	0.3	0.6	1.5	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.5	-0.8	-0.3	-0.9	0.2	-0.0	1.2	-0.9	-0.8	-0.0	-0.7	-0.9	-1.1	-0.9	-0.3	-0.8	-0.7	-0.7
Medication: Blood pressure	0.4	0.8	3.8	0.1	-1.9	0.1	-0.9	-1.4	0.0	-0.4	0.2	-1.8	-0.2	-0.4	0.3	-0.5	0.1	0.2	1.6	0.0
Migraine (self-reported)	0.4	0.5	4.6	-0.4	0.6	-0.2	1.3	0.4	2.1	-0.2	-0.4	0.4	-0.4	-0.1	-0.2	-0.1	-0.5	-0.3	-0.8	-0.5
Medication: Omeprazole	0.4	0.5	2.2	0.4	-1.5	0.4	0.3	-1.0	-1.1	-0.1	0.5	-1.1	0.3	-0.6	0.5	-0.0	-0.3	0.4	0.8	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	4.9	0.2	0.2	0.3	2.2	-0.4	-0.2	0.1	0.2	-0.5	0.4	-0.9	0.3	0.2	-1.2	0.2	-0.4	0.2
Average weekly red wine intake	0.4	0.6	3.0	-0.5	1.7	-0.3	1.2	0.2	0.8	0.4	-0.5	1.1	-0.4	0.4	-0.1	0.4	-0.8	-0.5	-1.0	-0.5
Mood swings	0.4	0.7	4.4	-0.7	-0.9	-0.2	1.0	-0.4	-0.0	-0.9	-0.5	-2.1	-0.8	-1.1	-0.1	-0.5	-1.1	-0.6	-0.1	-0.7
Commuting to job workplace: Walk	0.4	0.4	1.8	-0.3	0.7	-0.5	1.2	0.1	-0.4	-0.3	-0.4	-0.1	-0.4	-0.7	-0.1	0.1	-1.3	-0.4	-1.0	-0.6
Eye problems/disorders: Cataract	0.4	0.5	2.0	0.6	0.2	0.7	0.5	0.5	1.4	0.4	0.6	0.4	0.4	1.1	0.6	0.8	1.0	0.6	0.8	0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.2	0.8	0.7	0.8	0.3	0.1	0.3	0.9	1.0	0.7	1.1	0.7	1.0	0.9	0.8	0.9	0.5	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	4.7	0.1	0.8	0.7	1.3	2.2	1.8	0.6	0.2	1.3	0.2	0.7	-0.1	0.7	0.4	0.2	-0.2	0.2
Commuting to job workplace: Public transport	0.4	0.5	2.2	0.7	0.7	0.7	0.1	1.5	-1.2	0.5	0.4	0.5	0.4	0.6	0.4	0.3	0.4	0.5	0.7	0.4
Medication: Bendroflumethiazide	0.4	0.6	1.6	-0.8	-1.0	-0.5	-0.5	-1.3	-0.5	-0.9	-0.6	-0.6	-0.6	-1.0	-0.8	-1.2	-0.6	-0.7	-0.8	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.2	-0.1	-1.5	-0.0	0.5	-0.9	-0.8	-0.6	-0.1	-1.3	-0.2	-1.2	-0.0	-0.4	-1.1	-0.2	0.1	-0.2
Crohns Disease (2017)	0.3	0.6	3.4	-0.5	-1.8	-0.6	-0.9	-0.7	0.3	-1.0	-0.5	-1.1	-0.6	-0.7	-0.7	-0.7	-0.1	-0.5	0.3	-0.5
Major Depression (MDD)	0.3	0.4	2.4	0.2	-1.5	-0.0	-0.7	0.0	-0.8	-0.3	0.2	-1.1	0.1	-0.8	0.0	-0.5	-0.5	0.2	0.3	0.2
Ovarian Cancer	0.3	0.4	1.8	-0.3	-1.2	0.0	-0.3	1.0	-1.2	-0.6	-0.2	-1.4	-0.3	-0.5	-0.0	-0.3	-0.3	-0.4	0.4	-0.3
Height	0.3	4.9	10.9	-2.4	-2.7	-1.7	-1.0	-2.0	-2.6	-2.5	-2.4	-1.1	-2.6	-1.6	-3.0	-3.3	-0.7	-2.4	-1.1	-2.4
Waist Hip Ratio (WHR)	0.3	1.2	6.4	-0.2	2.5	-0.4	1.1	1.5	-0.1	0.8	-0.4	2.5	-0.1	1.3	-0.1	0.8	0.5	-0.2	-1.0	-0.2
Systolic Blood Pressure	0.3	1.7	6.9	-0.8	-2.6	-0.5	-0.9	-1.6	-1.3	-1.7	-0.8	-1.9	-1.1	-1.6	-1.1	-1.4	-0.7	-0.9	-0.2	-0.9
Allergy or Eczema	0.3	0.8	4.4	-0.2	1.8	-0.3	1.4	0.6	-1.1	0.3	-0.5	2.1	-0.2	1.0	-0.3	0.3	0.4	-0.3	-0.5	-0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.1	0.6	0.0	0.7	0.2	-1.0	0.7	0.5	0.7	-1.1	0.6	-0.2	0.9	0.4	-0.5	0.6	0.2	0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.5	0.4	-0.3	0.5	-1.0	0.2	0.9	0.4	0.6	0.7	0.5	0.4	0.0	0.2	1.2	0.5	0.4	0.6
Sitting height	0.3	2.0	10.4	-0.5	-3.2	-0.1	-1.2	-2.4	-1.3	-1.5	-0.3	-2.6	-0.6	-1.2	-0.8	-1.5	-0.2	-0.5	0.9	-0.4
Nervous feelings	0.3	0.5	0.8	-0.9	-0.7	-0.8	0.5	-0.3	0.6	-0.7	-0.9	-0.5	-0.8	-0.8	-0.7	-0.5	-0.5	-0.8	-0.6	-0.8
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.5	0.1	1.4	0.2	0.3	0.4	-0.5	0.5	-0.2	1.6	0.1	1.2	0.1	0.3	0.7	-0.1	-0.3	-0.0
Father’s age at death	0.3	0.5	3.8	-0.3	1.1	-0.3	0.0	0.8	0.5	0.3	-0.3	1.9	-0.1	0.6	-0.4	0.1	0.1	-0.3	-0.9	-0.2
Number of full brothers	0.3	0.4	1.5	0.2	-1.1	-0.0	-0.9	-0.5	-1.2	-0.3	0.4	-1.1	0.3	-0.3	0.3	0.1	-0.4	0.2	0.4	0.3
Medication: Allopurinol	0.3	0.4	1.6	0.4	-0.3	0.3	-0.9	0.6	1.3	0.3	0.3	0.4	0.2	1.1	0.5	0.7	0.9	0.4	0.9	0.3
Heart disease (mother)	0.3	0.4	0.8	-0.7	-0.4	-0.2	0.3	-0.3	-0.4	-0.8	-0.6	-0.3	-0.7	-0.8	-0.8	-0.9	-0.7	-0.6	-0.6	-0.6
Number of full sisters	0.3	0.4	1.1	-0.2	-0.9	-0.1	-0.5	-0.4	0.3	-0.9	-0.3	-0.7	-0.4	-1.1	-0.8	-0.8	-0.2	-0.3	-0.7	-0.3
Knee pain experienced in last month	0.3	0.5	2.3	0.0	-1.3	-0.1	-0.2	-1.0	-1.5	-0.5	-0.0	-1.2	-0.1	-0.9	-0.3	-0.8	-0.3	-0.0	0.1	-0.0
Fractured/broken bones in last 5 years	0.3	0.4	2.0	0.2	0.4	0.4	1.2	0.5	1.4	0.4	0.3	0.7	0.2	0.8	0.2	0.4	1.1	0.3	0.6	0.3
Irritable Bowel Disease (IBD)	0.2	0.6	3.3	0.3	-1.8	0.2	-0.7	-0.0	0.8	-0.3	0.4	-1.2	0.3	-0.1	0.2	-0.1	0.8	0.4	1.5	0.5
HbA1C	0.2	0.2	0.9	0.2	-0.1	0.6	1.0	0.3	-0.6	0.2	0.2	-0.1	0.3	0.2	0.3	0.4	0.5	0.2	0.8	0.3
HDL Cholesterol	0.2	0.4	2.1	0.1	0.6	0.2	1.5	0.6	-1.1	0.4	0.2	-0.2	0.4	-0.0	0.5	0.7	-0.8	0.1	-0.1	0.2
LDL Cholesterol	0.2	0.3	0.8	-0.7	0.0	-0.9	-0.7	-0.2	0.2	-0.6	-0.8	0.4	-0.6	-0.3	-0.7	-0.5	-0.4	-0.8	-0.6	-0.6
Tanning	0.2	2.6	4.8	-1.7	-2.2	-1.7	-1.3	-1.5	0.5	-1.5	-1.6	-1.4	-1.8	-1.9	-1.7	-1.8	-1.8	-1.6	-1.1	-1.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	-0.5	-0.3	-0.5	-0.7	0.1	0.1	-0.3	-0.4	0.4	-0.5	-0.1	-0.6	-0.5	0.4	-0.4	-0.3	-0.4
Medication for hormone replacement therapy	0.2	0.2	0.6	-0.6	0.3	-0.7	0.5	-0.1	0.4	-0.1	-0.6	0.6	-0.5	0.2	-0.4	-0.1	-0.3	-0.6	-0.8	-0.6
Taking other prescription medications	0.2	0.3	1.8	0.3	-1.4	0.3	-0.2	-0.9	-0.6	-0.3	0.3	-0.3	0.3	-0.4	-0.2	-0.9	0.7	0.2	0.5	0.4
Diabetes (self-reported)	0.2	0.3	0.8	0.5	-0.8	0.9	0.6	0.2	-0.7	0.3	0.6	-0.2	0.4	0.1	0.4	0.0	0.2	0.5	0.7	0.5
Hair/balding pattern: Pattern 3	0.2	0.3	1.3	-0.2	-0.4	-0.7	-1.1	-0.1	-0.5	-0.4	-0.4	0.4	-0.4	-0.4	-0.6	-0.6	-0.2	-0.4	-0.6	-0.4
Mouth/teeth dental problems: Dentures	0.2	0.3	2.0	0.0	-1.4	-0.2	-0.3	-0.9	-1.1	-0.2	0.1	-0.6	-0.2	-0.2	-0.2	-0.3	0.6	0.2	0.8	0.0
Standing height	0.2	1.8	4.2	-1.7	-0.9	-1.1	0.4	-0.3	-1.4	-1.5	-1.8	0.3	-1.7	-0.6	-2.1	-1.9	-0.6	-1.7	-1.2	-1.7
Exposure to tobacco smoke at home	0.2	0.3	1.2	0.1	-0.7	0.3	1.1	-0.8	-0.3	-0.5	-0.1	-0.9	-0.1	-0.8	-0.4	-0.2	0.1	-0.0	0.3	-0.1
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	0.8	-0.3	1.1	0.7	-0.6	-0.9	0.7	0.8	0.3	0.7	0.5	0.4	0.4	0.9	0.8	0.7	0.8
Headache pain in last month	0.2	0.4	1.9	0.3	-0.7	0.7	0.6	-0.5	-0.3	-0.1	0.5	-1.4	0.4	-0.8	0.6	0.1	-0.7	0.4	0.4	0.4
Forced vital capacity (FVC), Best measure	0.2	0.6	3.4	0.1	0.9	0.7	1.6	1.8	0.8	0.6	0.2	0.6	0.2	0.8	0.2	0.5	0.2	0.2	0.1	0.2
Emphysema/chronic bronchitis	0.2	0.2	1.9	-0.3	-0.6	-0.2	-0.3	-0.1	-1.4	-0.3	-0.2	0.1	-0.4	-0.5	-0.5	-0.7	0.0	-0.2	-0.4	-0.3
Medication: Seretide 50 evohaler	0.2	0.2	0.8	-0.4	0.8	-0.6	-0.4	0.1	0.3	-0.1	-0.4	0.8	-0.4	0.6	-0.5	-0.1	0.9	-0.3	-0.0	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	0.5	-0.5	0.4	0.3	0.6	0.4	0.1	0.4	-0.8	0.4	0.0	0.6	0.1	0.4	0.5	0.7	0.5
Comparative height size at age 10	0.2	1.1	2.5	-1.0	-1.6	-0.6	-0.5	-1.4	-1.0	-1.2	-0.8	-1.3	-0.9	-1.4	-1.0	-1.4	-0.9	-0.9	-0.3	-0.9
Had major operations	0.2	0.2	1.1	-0.3	0.2	-0.4	0.6	-0.9	0.4	-0.3	-0.1	-1.1	-0.4	-0.5	-0.0	-0.0	-0.8	-0.2	-0.4	-0.4
Family relationship satisfaction	0.2	0.3	0.6	-0.5	-0.4	-0.5	0.3	0.2	-0.0	-0.8	-0.6	-0.5	-0.8	-0.2	-0.7	-0.7	-0.1	-0.6	0.2	-0.6
Diabetes diagnosed by doctor	0.2	0.4	2.2	0.0	-1.5	0.3	-0.4	-0.5	-1.2	-0.5	0.1	-0.7	-0.2	-0.2	-0.2	-0.7	0.3	-0.0	0.7	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.0	0.0	-0.4	0.5	0.9	-0.1	-1.0	0.1	0.3	-0.7	0.2	-0.1	0.4	-0.3	-0.4	0.2	0.0	0.2
Friendships satisfaction	0.2	0.2	1.8	-0.1	-0.7	-0.2	-0.3	0.1	-1.3	-0.4	-0.3	-0.5	-0.4	0.2	-0.2	-0.3	0.2	-0.2	0.6	-0.2
Breast cancer (self-reported)	0.2	0.2	1.5	-0.1	-0.1	-0.2	-1.2	-1.0	-0.2	-0.4	-0.2	-0.1	-0.3	-0.1	-0.3	-0.3	-0.1	-0.2	0.0	-0.3
Medication: Gliclazide	0.2	0.3	2.4	0.1	0.4	0.3	0.9	-0.4	-1.6	0.4	0.3	0.5	0.3	0.3	0.3	0.4	-0.0	0.2	0.1	0.3
Risk taking	0.2	0.3	2.1	-0.2	-0.1	0.1	1.5	-0.6	-1.4	0.0	-0.1	-0.4	0.0	-0.3	0.0	-0.1	-0.4	-0.1	-0.5	-0.1
Basal cell carcinoma (self-reported)	0.2	0.3	1.1	-0.0	-1.0	-0.2	-0.8	-0.6	-0.1	-0.3	0.0	-0.5	-0.1	-0.1	-0.3	-0.3	0.9	0.1	1.1	0.1
Alcohol drinker status: Previous	0.2	0.3	0.8	-0.6	0.4	-0.9	-0.2	0.0	0.3	-0.3	-0.7	0.7	-0.6	0.0	-0.6	-0.5	0.2	-0.6	-0.6	-0.6
Breast Cancer	0.1	0.2	0.9	0.3	-0.4	1.0	0.9	0.1	-0.2	-0.0	0.5	-0.7	0.4	-0.2	0.4	0.1	0.2	0.5	0.5	0.5
Crohns Disease (2012)	0.1	0.2	0.5	-0.3	-0.5	-0.6	-0.4	0.3	0.6	-0.4	-0.6	0.5	-0.5	0.3	-0.7	-0.1	0.3	-0.5	-0.1	-0.4
Blood Red Count	0.1	1.1	6.2	0.3	-2.5	0.1	-1.8	-0.1	0.9	-0.7	0.4	-2.3	-0.0	-1.1	-0.2	-0.8	0.1	0.3	1.0	0.2
Blood White Count	0.1	0.5	2.1	-0.7	0.0	-1.3	-1.5	-0.6	-0.3	-0.5	-0.7	0.5	-0.8	0.2	-0.8	-0.7	0.1	-0.6	-0.6	-0.7
Type 2 Diabetes (T2D) (2018)	0.1	0.3	1.4	0.3	-1.2	0.7	-0.3	0.1	-0.1	-0.3	0.3	-1.2	0.1	-0.5	0.2	-0.6	-0.2	0.2	0.5	0.2
Hair Pigment	0.1	4.2	6.9	2.6	0.6	2.1	0.6	1.0	1.0	1.9	2.5	0.7	2.5	2.0	2.3	2.3	2.6	2.5	2.5	2.6
Maternal smoking around birth	0.1	0.2	0.5	0.3	-0.5	0.7	0.0	0.2	-0.6	-0.0	0.5	-0.6	0.4	-0.1	0.1	0.1	0.4	0.4	0.5	0.5
Relative age voice broke	0.1	0.2	0.7	-0.4	-0.2	-0.2	0.2	0.0	0.2	-0.8	-0.5	-0.6	-0.8	-0.2	-0.6	-0.0	-0.2	-0.4	-0.1	-0.6
Qualifications: CSEs or equivalent	0.1	0.2	1.1	0.3	-0.2	0.2	-0.3	-0.0	1.1	-0.2	0.1	-1.0	0.0	-0.2	0.2	0.1	0.1	0.0	0.5	0.1
Past tobacco smoking	0.1	0.2	1.4	-0.5	0.5	-0.0	-0.1	1.2	-0.4	-0.0	-0.4	0.6	-0.3	-0.2	-0.5	-0.1	-0.3	-0.4	-0.7	-0.3
Asthma	0.1	0.3	0.7	-0.8	0.3	-0.5	-0.8	0.3	-0.2	-0.7	-0.6	0.4	-0.7	-0.1	-0.6	-0.4	-0.1	-0.6	-0.6	-0.6
Depression (self-reported)	0.1	0.1	0.4	0.0	-0.7	-0.2	-0.4	-0.2	-0.4	-0.0	0.1	-0.5	0.1	-0.4	0.1	-0.2	-0.3	0.1	-0.4	0.1
Breastfed as a baby	0.1	0.2	0.9	0.1	0.6	-0.2	-0.2	0.5	-1.0	0.3	-0.0	0.8	0.2	0.3	0.1	0.2	-0.0	-0.0	-0.3	0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.4	-0.2	-0.3	0.3	-0.7	-0.1	-0.2	-0.4	-0.1	-0.5	-0.3	-0.1	0.0	-0.2	0.2	-0.2	0.5	-0.1
Smoking status: Previous	0.1	0.2	1.1	0.0	0.3	-0.3	0.7	-1.1	0.4	0.1	-0.0	0.5	-0.0	0.7	0.1	0.2	0.4	-0.0	-0.0	-0.0
Asthma (self-reported)	0.1	0.2	0.7	-0.7	0.1	-0.3	-0.8	0.2	-0.4	-0.6	-0.4	0.1	-0.5	-0.3	-0.5	-0.4	-0.2	-0.5	-0.5	-0.5
Commuting to job workplace: Cycle	0.1	0.1	0.6	-0.3	0.2	0.0	-0.5	0.4	-0.1	-0.1	-0.4	0.8	-0.3	0.3	-0.5	-0.3	0.1	-0.4	-0.5	-0.3
Blood Eosinophil Count	0.0	0.2	0.6	0.6	-0.2	0.7	0.5	0.8	0.6	0.1	0.3	-0.5	-0.3	0.2	0.0	0.2	0.6	0.5	0.6	0.1
Medication: Amlodipine	0.0	0.1	0.3	0.2	0.0	0.1	-0.6	0.2	0.2	0.0	0.1	-0.1	0.1	0.2	0.2	-0.0	0.2	0.1	0.4	0.1

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