[Hub]/) : Traits : Impedance of arm (right) :

chr19:3,268,722-5,153,606

Best TWAS P=2.03e-12 · Best GWAS P=3.52e-11 conditioned to 0.457

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex UBXN6 0.27 0.25 enet 28 0.29 4.6e-36 -5.2 5.8 6.0e-09 0.51 0.93 0.07 FALSE
2 GTEx Adipose Subcutaneous UBXN6 0.10 0.00 enet 21 0.02 8.0e-03 6.6 5.4 7.0e-08 0.66 0.01 0.95 FALSE
3 GTEx Adipose Subcutaneous CTB-50L17.9 0.29 0.30 lasso 2 0.30 2.3e-24 -5.3 5.4 8.7e-08 0.49 0.90 0.10 FALSE
4 GTEx Adipose Visceral Omentum CTB-50L17.9 0.30 0.23 lasso 4 0.22 2.1e-11 -5.3 5.2 2.0e-07 0.43 0.87 0.13 FALSE
5 GTEx Adrenal Gland CHAF1A 0.22 0.18 lasso 3 0.17 1.1e-06 -4.9 5.2 2.4e-07 0.51 0.70 0.10 FALSE
6 GTEx Adrenal Gland CTB-50L17.9 0.38 0.35 lasso 3 0.34 5.8e-13 -5.3 5.3 9.6e-08 0.49 0.89 0.11 FALSE
7 GTEx Artery Aorta MPND 0.14 0.06 lasso 2 0.03 6.7e-03 -5.0 -5.1 3.1e-07 -0.48 0.22 0.11 FALSE
8 GTEx Artery Aorta UBXN6 0.13 0.02 lasso 5 0.03 5.7e-03 6.6 7.0 2.0e-12 0.89 0.01 0.98 TRUE
9 GTEx Artery Aorta CTB-50L17.5 0.16 0.15 lasso 7 0.15 1.0e-08 -5.8 5.7 1.0e-08 0.53 0.62 0.38 FALSE
10 GTEx Artery Aorta CTB-50L17.9 0.32 0.31 lasso 4 0.30 2.9e-17 -5.3 5.5 3.3e-08 0.53 0.87 0.13 FALSE
11 GTEx Artery Coronary CTB-50L17.9 0.43 0.14 lasso 6 0.12 6.5e-05 -5.3 5.9 4.4e-09 0.44 0.19 0.18 FALSE
12 GTEx Artery Tibial UBXN6 0.18 0.07 lasso 3 0.14 6.3e-11 -5.0 6.2 4.9e-10 0.74 0.03 0.97 FALSE
13 GTEx Artery Tibial CTB-50L17.9 0.27 0.31 lasso 3 0.31 2.2e-24 -5.3 5.4 7.6e-08 0.49 0.91 0.09 FALSE
14 GTEx Brain Caudate basal ganglia CTB-50L17.9 0.27 0.25 lasso 2 0.24 1.8e-07 -5.8 6.0 2.1e-09 0.54 0.23 0.47 FALSE
15 GTEx Brain Cerebellar Hemisphere CHAF1A 0.62 0.40 lasso 8 0.36 3.5e-10 -5.8 5.8 5.4e-09 0.54 0.62 0.37 FALSE
16 GTEx Brain Cerebellar Hemisphere CTB-50L17.9 0.61 0.45 lasso 2 0.50 1.2e-14 -5.3 5.4 6.0e-08 0.50 0.76 0.24 FALSE
17 GTEx Brain Cerebellum CHAF1A 0.51 0.35 lasso 4 0.34 9.7e-11 -5.8 5.6 1.9e-08 0.54 0.69 0.30 FALSE
18 GTEx Brain Cerebellum CTB-50L17.5 0.33 0.22 lasso 4 0.20 1.8e-06 -5.3 5.4 8.8e-08 0.50 0.63 0.23 FALSE
19 GTEx Brain Cerebellum CTB-50L17.9 0.53 0.41 lasso 2 0.50 3.6e-17 -5.3 6.1 9.6e-10 0.65 0.65 0.35 FALSE
20 GTEx Brain Cortex CTB-50L17.9 0.28 0.25 lasso 2 0.25 1.7e-07 -5.3 5.4 6.0e-08 0.51 0.16 0.78 FALSE
21 GTEx Brain Frontal Cortex BA9 UBXN6 0.31 0.06 enet 5 0.12 3.5e-04 -5.3 5.4 7.2e-08 0.52 0.14 0.21 FALSE
22 GTEx Brain Frontal Cortex BA9 CTB-50L17.9 0.27 0.21 lasso 3 0.19 7.9e-06 -5.3 6.0 2.0e-09 0.62 0.17 0.69 FALSE
23 GTEx Brain Nucleus accumbens basal ganglia CHAF1A 0.31 0.28 lasso 2 0.24 4.0e-07 -5.4 5.4 8.2e-08 0.52 0.34 0.42 FALSE
24 GTEx Brain Nucleus accumbens basal ganglia CTB-50L17.9 0.45 0.25 lasso 8 0.23 8.6e-07 -5.8 6.8 1.1e-11 0.71 0.06 0.90 FALSE
25 GTEx Brain Putamen basal ganglia CHAF1A 0.40 0.34 lasso 4 0.37 1.2e-09 -5.8 5.3 1.1e-07 0.54 0.32 0.39 FALSE
26 GTEx Brain Putamen basal ganglia CTB-50L17.9 0.33 0.32 lasso 1 0.33 1.2e-08 -5.3 5.3 8.9e-08 0.49 0.28 0.54 FALSE
27 GTEx Breast Mammary Tissue CTB-50L17.9 0.42 0.33 lasso 9 0.32 3.0e-17 -5.3 5.4 6.6e-08 0.50 0.85 0.15 FALSE
28 GTEx Breast Mammary Tissue (Male) CTB-50L17.9 0.30 0.18 lasso 4 0.10 2.3e-03 -5.3 5.3 1.2e-07 0.48 0.05 0.30 FALSE
29 GTEx Breast Mammary Tissue (Female) CHAF1A 0.33 0.14 lasso 6 0.09 1.6e-03 -5.4 5.2 2.5e-07 0.48 0.34 0.10 FALSE
30 GTEx Breast Mammary Tissue (Female) CTB-50L17.9 0.45 0.25 lasso 7 0.26 1.6e-08 -5.5 5.3 9.5e-08 0.48 0.47 0.42 FALSE
31 GTEx Cells EBV-transformed lymphocytes CTB-50L17.9 0.31 0.27 lasso 1 0.23 3.6e-08 -5.3 5.3 8.9e-08 0.49 0.80 0.14 FALSE
32 GTEx Cells Transformed fibroblasts UBXN6 0.09 0.10 lasso 1 0.08 1.5e-06 6.6 6.6 3.6e-11 0.99 0.00 1.00 FALSE
33 GTEx Colon Sigmoid UBXN6 0.34 0.15 lasso 6 0.14 1.7e-05 -5.3 6.0 1.6e-09 0.65 0.08 0.89 FALSE
34 GTEx Colon Sigmoid CTB-50L17.9 0.42 0.38 lasso 5 0.37 4.4e-14 -5.3 5.4 5.4e-08 0.50 0.79 0.21 FALSE
35 GTEx Esophagus Gastroesophageal Junction CTB-50L17.9 0.22 0.18 lasso 2 0.19 1.7e-07 -5.3 5.4 5.5e-08 0.49 0.78 0.16 FALSE
36 GTEx Esophagus Mucosa CTB-50L17.9 0.20 0.23 lasso 4 0.22 8.2e-15 -5.3 5.4 7.0e-08 0.49 0.88 0.12 FALSE
37 GTEx Esophagus Muscularis UBXN6 0.35 0.24 enet 20 0.29 3.7e-18 -5.3 6.0 2.3e-09 0.57 0.73 0.27 FALSE
38 GTEx Esophagus Muscularis CTB-50L17.9 0.37 0.36 lasso 5 0.35 3.8e-22 -5.3 5.4 6.4e-08 0.50 0.87 0.13 FALSE
39 GTEx Esophagus Muscularis AC007292.6 0.13 0.08 lasso 2 0.05 4.9e-04 -5.2 5.4 6.0e-08 0.49 0.54 0.12 FALSE
40 GTEx Heart Atrial Appendage UBXN6 0.34 0.12 lasso 6 0.21 6.5e-10 -5.8 6.7 1.6e-11 0.86 0.01 0.99 FALSE
41 GTEx Heart Atrial Appendage CTB-50L17.9 0.32 0.34 lasso 3 0.34 3.8e-16 -5.3 5.7 1.0e-08 0.60 0.89 0.11 FALSE
42 GTEx Heart Left Ventricle CHAF1A 0.17 0.12 lasso 2 0.11 1.9e-06 -5.8 5.8 7.4e-09 0.54 0.55 0.36 FALSE
43 GTEx Heart Left Ventricle UBXN6 0.21 0.14 lasso 6 0.16 5.6e-09 6.6 7.0 2.8e-12 0.95 0.01 0.99 FALSE
44 GTEx Heart Left Ventricle CTB-50L17.9 0.25 0.17 lasso 2 0.18 5.4e-10 -5.3 5.1 2.8e-07 0.47 0.85 0.14 FALSE
45 GTEx Lung CTB-50L17.9 0.23 0.32 lasso 2 0.32 2.4e-25 -5.5 5.5 4.7e-08 0.49 0.84 0.16 FALSE
46 GTEx Muscle Skeletal MPND 0.10 0.07 lasso 3 0.05 6.3e-06 -5.2 -5.2 2.0e-07 -0.50 0.84 0.15 FALSE
47 GTEx Muscle Skeletal CHAF1A 0.18 0.21 lasso 2 0.20 9.7e-20 -5.8 5.7 1.4e-08 0.54 0.59 0.41 FALSE
48 GTEx Muscle Skeletal UBXN6 0.19 0.14 lasso 5 0.18 4.1e-17 6.6 7.0 2.5e-12 0.92 0.00 1.00 FALSE
49 GTEx Muscle Skeletal CTB-50L17.9 0.23 0.23 lasso 5 0.21 2.0e-20 -5.3 5.5 4.4e-08 0.51 0.90 0.10 FALSE
50 GTEx Muscle Skeletal AC007292.3 0.08 0.03 lasso 3 0.04 1.4e-04 -5.2 -5.3 1.4e-07 -0.49 0.72 0.20 FALSE
51 GTEx Nerve Tibial UBXN6 0.17 0.08 enet 20 0.09 4.4e-07 -5.5 5.8 6.5e-09 0.46 0.80 0.17 FALSE
52 GTEx Nerve Tibial CTB-50L17.5 0.11 0.08 enet 4 0.08 1.6e-06 -5.4 5.6 1.9e-08 0.53 0.75 0.24 FALSE
53 GTEx Nerve Tibial CTB-50L17.9 0.35 0.41 lasso 1 0.40 2.1e-30 -5.3 5.3 8.9e-08 0.49 0.90 0.10 FALSE
54 GTEx Ovary CTB-50L17.9 0.29 0.24 lasso 2 0.21 6.5e-06 -5.5 5.5 3.9e-08 0.49 0.18 0.60 FALSE
55 GTEx Pancreas CTB-50L17.9 0.24 0.15 lasso 4 0.07 1.0e-03 -5.3 5.5 3.7e-08 0.49 0.63 0.10 FALSE
56 GTEx Prostate MIR637 0.30 -0.01 lasso 6 -0.01 5.5e-01 6.6 5.7 1.5e-08 0.83 0.02 0.59 FALSE
57 GTEx Skin Not Sun Exposed Suprapubic CTB-50L17.9 0.43 0.52 lasso 2 0.51 3.3e-32 -5.3 5.4 7.9e-08 0.50 0.90 0.10 FALSE
58 GTEx Skin Sun Exposed Lower leg CHAF1A 0.19 0.18 lasso 1 0.17 5.1e-14 -5.4 5.4 8.5e-08 0.52 0.80 0.20 FALSE
59 GTEx Skin Sun Exposed Lower leg UBXN6 0.14 0.00 enet 31 0.00 7.1e-01 6.1 5.3 1.1e-07 0.47 0.03 0.72 FALSE
60 GTEx Skin Sun Exposed Lower leg CTB-50L17.9 0.39 0.48 lasso 3 0.47 7.7e-44 -5.3 5.4 8.4e-08 0.49 0.91 0.09 FALSE
61 GTEx Small Intestine Terminal Ileum CTB-50L17.9 0.46 0.34 lasso 4 0.36 7.2e-09 -5.3 5.3 1.2e-07 0.49 0.42 0.36 FALSE
62 GTEx Stomach CTB-50L17.9 0.28 0.31 lasso 1 0.31 3.6e-15 -5.3 5.3 8.9e-08 0.49 0.88 0.12 FALSE
63 GTEx Stomach AC007292.4 0.27 0.09 lasso 5 0.04 4.0e-03 6.1 -5.5 4.0e-08 -0.81 0.05 0.70 FALSE
64 GTEx Testis CHAF1A 0.18 0.09 lasso 2 0.07 4.0e-04 -5.8 5.7 9.2e-09 0.53 0.08 0.52 FALSE
65 GTEx Testis UBXN6 0.20 0.10 lasso 3 0.10 2.9e-05 -5.3 5.6 2.4e-08 0.51 0.71 0.14 FALSE
66 GTEx Testis CTB-50L17.9 0.39 0.30 enet 36 0.34 9.4e-16 -5.3 5.1 3.0e-07 0.22 0.86 0.14 FALSE
67 GTEx Thyroid UBXN6 0.25 0.19 lasso 5 0.23 8.8e-18 -5.0 5.5 4.2e-08 0.50 0.90 0.10 FALSE
68 GTEx Thyroid CTB-50L17.9 0.35 0.42 lasso 2 0.42 2.2e-34 -5.3 5.3 8.9e-08 0.49 0.90 0.10 FALSE
69 GTEx Vagina CTB-50L17.9 0.38 0.26 lasso 5 0.23 5.7e-06 -5.8 5.8 5.7e-09 0.56 0.23 0.41 FALSE
70 GTEx Whole Blood UBXN6 0.06 0.03 lasso 4 0.01 4.1e-02 6.1 5.7 1.2e-08 0.91 0.02 0.97 FALSE
71 GTEx Whole Blood CTB-50L17.9 0.21 0.17 lasso 3 0.18 9.6e-17 -5.3 5.4 8.2e-08 0.50 0.80 0.20 FALSE
72 The Cancer Genome Atlas Breast Invasive Carcinoma UBXN6 0.03 0.03 lasso 3 0.03 2.3e-06 6.6 6.9 5.9e-12 0.97 0.00 1.00 FALSE
73 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma UBXN6 0.05 0.01 blup 57 0.04 6.6e-05 -5.8 6.1 1.1e-09 0.62 0.04 0.89 FALSE
74 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHAF1A 0.12 0.11 lasso 3 0.12 7.9e-13 -5.4 5.5 3.1e-08 0.50 0.88 0.12 FALSE
75 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MPND 0.05 0.03 lasso 3 0.02 5.3e-03 -5.4 -5.4 7.0e-08 -0.50 0.07 0.31 FALSE
76 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma UBXN6 0.18 0.17 enet 18 0.18 9.9e-20 -5.8 5.7 1.2e-08 0.51 0.52 0.48 FALSE
77 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CHAF1A 0.15 0.12 lasso 2 0.12 3.2e-07 -5.4 5.5 3.4e-08 0.52 0.83 0.16 FALSE
78 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma UBXN6 0.15 0.10 lasso 1 0.10 2.8e-06 -5.3 5.3 8.9e-08 0.49 0.54 0.19 FALSE
79 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UBXN6 0.04 0.03 lasso 2 0.02 1.6e-03 -5.3 5.7 1.2e-08 0.53 0.06 0.14 FALSE
80 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CHAF1A 0.20 0.11 lasso 2 0.11 5.6e-05 -5.0 5.5 4.1e-08 0.49 0.26 0.24 FALSE
81 The Cancer Genome Atlas Prostate Adenocarcinoma UBXN6 0.13 0.10 lasso 2 0.10 1.3e-10 -5.8 6.0 2.3e-09 0.56 0.46 0.54 FALSE
82 The Cancer Genome Atlas Thyroid Carcinoma UBXN6 0.16 0.12 lasso 2 0.12 5.4e-12 -5.8 6.1 8.6e-10 0.62 0.45 0.55 FALSE