[Hub]/) : Traits : Impedance of arm (right) : ← →

chr19:3,268,722-5,153,606

Best TWAS P=2.03e-12 · Best GWAS P=3.52e-11 conditioned to 0.457

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Artery Aorta	UBXN6	0.13	0.02	lasso	5	0.03	5.7e-03	6.6	7.0	2.0e-12	0.89	0.01	0.98	TRUE
48	GTEx	Muscle Skeletal	UBXN6	0.19	0.14	lasso	5	0.18	4.1e-17	6.6	7.0	2.5e-12	0.92	0.00	1.00	FALSE
43	GTEx	Heart Left Ventricle	UBXN6	0.21	0.14	lasso	6	0.16	5.6e-09	6.6	7.0	2.8e-12	0.95	0.01	0.99	FALSE
72	The Cancer Genome Atlas	Breast Invasive Carcinoma	UBXN6	0.03	0.03	lasso	3	0.03	2.3e-06	6.6	6.9	5.9e-12	0.97	0.00	1.00	FALSE
24	GTEx	Brain Nucleus accumbens basal ganglia	CTB-50L17.9	0.45	0.25	lasso	8	0.23	8.6e-07	-5.8	6.8	1.1e-11	0.71	0.06	0.90	FALSE
40	GTEx	Heart Atrial Appendage	UBXN6	0.34	0.12	lasso	6	0.21	6.5e-10	-5.8	6.7	1.6e-11	0.86	0.01	0.99	FALSE
32	GTEx	Cells Transformed fibroblasts	UBXN6	0.09	0.10	lasso	1	0.08	1.5e-06	6.6	6.6	3.6e-11	0.99	0.00	1.00	FALSE
12	GTEx	Artery Tibial	UBXN6	0.18	0.07	lasso	3	0.14	6.3e-11	-5.0	6.2	4.9e-10	0.74	0.03	0.97	FALSE
82	The Cancer Genome Atlas	Thyroid Carcinoma	UBXN6	0.16	0.12	lasso	2	0.12	5.4e-12	-5.8	6.1	8.6e-10	0.62	0.45	0.55	FALSE
19	GTEx	Brain Cerebellum	CTB-50L17.9	0.53	0.41	lasso	2	0.50	3.6e-17	-5.3	6.1	9.6e-10	0.65	0.65	0.35	FALSE
73	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UBXN6	0.05	0.01	blup	57	0.04	6.6e-05	-5.8	6.1	1.1e-09	0.62	0.04	0.89	FALSE
33	GTEx	Colon Sigmoid	UBXN6	0.34	0.15	lasso	6	0.14	1.7e-05	-5.3	6.0	1.6e-09	0.65	0.08	0.89	FALSE
22	GTEx	Brain Frontal Cortex BA9	CTB-50L17.9	0.27	0.21	lasso	3	0.19	7.9e-06	-5.3	6.0	2.0e-09	0.62	0.17	0.69	FALSE
14	GTEx	Brain Caudate basal ganglia	CTB-50L17.9	0.27	0.25	lasso	2	0.24	1.8e-07	-5.8	6.0	2.1e-09	0.54	0.23	0.47	FALSE
37	GTEx	Esophagus Muscularis	UBXN6	0.35	0.24	enet	20	0.29	3.7e-18	-5.3	6.0	2.3e-09	0.57	0.73	0.27	FALSE
81	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBXN6	0.13	0.10	lasso	2	0.10	1.3e-10	-5.8	6.0	2.3e-09	0.56	0.46	0.54	FALSE
11	GTEx	Artery Coronary	CTB-50L17.9	0.43	0.14	lasso	6	0.12	6.5e-05	-5.3	5.9	4.4e-09	0.44	0.19	0.18	FALSE
15	GTEx	Brain Cerebellar Hemisphere	CHAF1A	0.62	0.40	lasso	8	0.36	3.5e-10	-5.8	5.8	5.4e-09	0.54	0.62	0.37	FALSE
69	GTEx	Vagina	CTB-50L17.9	0.38	0.26	lasso	5	0.23	5.7e-06	-5.8	5.8	5.7e-09	0.56	0.23	0.41	FALSE
1	CommonMind	Brain Pre-frontal Cortex	UBXN6	0.27	0.25	enet	28	0.29	4.6e-36	-5.2	5.8	6.0e-09	0.51	0.93	0.07	FALSE
51	GTEx	Nerve Tibial	UBXN6	0.17	0.08	enet	20	0.09	4.4e-07	-5.5	5.8	6.5e-09	0.46	0.80	0.17	FALSE
42	GTEx	Heart Left Ventricle	CHAF1A	0.17	0.12	lasso	2	0.11	1.9e-06	-5.8	5.8	7.4e-09	0.54	0.55	0.36	FALSE
64	GTEx	Testis	CHAF1A	0.18	0.09	lasso	2	0.07	4.0e-04	-5.8	5.7	9.2e-09	0.53	0.08	0.52	FALSE
9	GTEx	Artery Aorta	CTB-50L17.5	0.16	0.15	lasso	7	0.15	1.0e-08	-5.8	5.7	1.0e-08	0.53	0.62	0.38	FALSE
41	GTEx	Heart Atrial Appendage	CTB-50L17.9	0.32	0.34	lasso	3	0.34	3.8e-16	-5.3	5.7	1.0e-08	0.60	0.89	0.11	FALSE
70	GTEx	Whole Blood	UBXN6	0.06	0.03	lasso	4	0.01	4.1e-02	6.1	5.7	1.2e-08	0.91	0.02	0.97	FALSE
76	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBXN6	0.18	0.17	enet	18	0.18	9.9e-20	-5.8	5.7	1.2e-08	0.51	0.52	0.48	FALSE
79	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBXN6	0.04	0.03	lasso	2	0.02	1.6e-03	-5.3	5.7	1.2e-08	0.53	0.06	0.14	FALSE
47	GTEx	Muscle Skeletal	CHAF1A	0.18	0.21	lasso	2	0.20	9.7e-20	-5.8	5.7	1.4e-08	0.54	0.59	0.41	FALSE
56	GTEx	Prostate	MIR637	0.30	-0.01	lasso	6	-0.01	5.5e-01	6.6	5.7	1.5e-08	0.83	0.02	0.59	FALSE
17	GTEx	Brain Cerebellum	CHAF1A	0.51	0.35	lasso	4	0.34	9.7e-11	-5.8	5.6	1.9e-08	0.54	0.69	0.30	FALSE
52	GTEx	Nerve Tibial	CTB-50L17.5	0.11	0.08	enet	4	0.08	1.6e-06	-5.4	5.6	1.9e-08	0.53	0.75	0.24	FALSE
65	GTEx	Testis	UBXN6	0.20	0.10	lasso	3	0.10	2.9e-05	-5.3	5.6	2.4e-08	0.51	0.71	0.14	FALSE
74	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CHAF1A	0.12	0.11	lasso	3	0.12	7.9e-13	-5.4	5.5	3.1e-08	0.50	0.88	0.12	FALSE
10	GTEx	Artery Aorta	CTB-50L17.9	0.32	0.31	lasso	4	0.30	2.9e-17	-5.3	5.5	3.3e-08	0.53	0.87	0.13	FALSE
77	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CHAF1A	0.15	0.12	lasso	2	0.12	3.2e-07	-5.4	5.5	3.4e-08	0.52	0.83	0.16	FALSE
55	GTEx	Pancreas	CTB-50L17.9	0.24	0.15	lasso	4	0.07	1.0e-03	-5.3	5.5	3.7e-08	0.49	0.63	0.10	FALSE
54	GTEx	Ovary	CTB-50L17.9	0.29	0.24	lasso	2	0.21	6.5e-06	-5.5	5.5	3.9e-08	0.49	0.18	0.60	FALSE
63	GTEx	Stomach	AC007292.4	0.27	0.09	lasso	5	0.04	4.0e-03	6.1	-5.5	4.0e-08	-0.81	0.05	0.70	FALSE
80	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CHAF1A	0.20	0.11	lasso	2	0.11	5.6e-05	-5.0	5.5	4.1e-08	0.49	0.26	0.24	FALSE
67	GTEx	Thyroid	UBXN6	0.25	0.19	lasso	5	0.23	8.8e-18	-5.0	5.5	4.2e-08	0.50	0.90	0.10	FALSE
49	GTEx	Muscle Skeletal	CTB-50L17.9	0.23	0.23	lasso	5	0.21	2.0e-20	-5.3	5.5	4.4e-08	0.51	0.90	0.10	FALSE
45	GTEx	Lung	CTB-50L17.9	0.23	0.32	lasso	2	0.32	2.4e-25	-5.5	5.5	4.7e-08	0.49	0.84	0.16	FALSE
34	GTEx	Colon Sigmoid	CTB-50L17.9	0.42	0.38	lasso	5	0.37	4.4e-14	-5.3	5.4	5.4e-08	0.50	0.79	0.21	FALSE
35	GTEx	Esophagus Gastroesophageal Junction	CTB-50L17.9	0.22	0.18	lasso	2	0.19	1.7e-07	-5.3	5.4	5.5e-08	0.49	0.78	0.16	FALSE
16	GTEx	Brain Cerebellar Hemisphere	CTB-50L17.9	0.61	0.45	lasso	2	0.50	1.2e-14	-5.3	5.4	6.0e-08	0.50	0.76	0.24	FALSE
20	GTEx	Brain Cortex	CTB-50L17.9	0.28	0.25	lasso	2	0.25	1.7e-07	-5.3	5.4	6.0e-08	0.51	0.16	0.78	FALSE
39	GTEx	Esophagus Muscularis	AC007292.6	0.13	0.08	lasso	2	0.05	4.9e-04	-5.2	5.4	6.0e-08	0.49	0.54	0.12	FALSE
38	GTEx	Esophagus Muscularis	CTB-50L17.9	0.37	0.36	lasso	5	0.35	3.8e-22	-5.3	5.4	6.4e-08	0.50	0.87	0.13	FALSE
27	GTEx	Breast Mammary Tissue	CTB-50L17.9	0.42	0.33	lasso	9	0.32	3.0e-17	-5.3	5.4	6.6e-08	0.50	0.85	0.15	FALSE
2	GTEx	Adipose Subcutaneous	UBXN6	0.10	0.00	enet	21	0.02	8.0e-03	6.6	5.4	7.0e-08	0.66	0.01	0.95	FALSE
36	GTEx	Esophagus Mucosa	CTB-50L17.9	0.20	0.23	lasso	4	0.22	8.2e-15	-5.3	5.4	7.0e-08	0.49	0.88	0.12	FALSE
75	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MPND	0.05	0.03	lasso	3	0.02	5.3e-03	-5.4	-5.4	7.0e-08	-0.50	0.07	0.31	FALSE
21	GTEx	Brain Frontal Cortex BA9	UBXN6	0.31	0.06	enet	5	0.12	3.5e-04	-5.3	5.4	7.2e-08	0.52	0.14	0.21	FALSE
13	GTEx	Artery Tibial	CTB-50L17.9	0.27	0.31	lasso	3	0.31	2.2e-24	-5.3	5.4	7.6e-08	0.49	0.91	0.09	FALSE
57	GTEx	Skin Not Sun Exposed Suprapubic	CTB-50L17.9	0.43	0.52	lasso	2	0.51	3.3e-32	-5.3	5.4	7.9e-08	0.50	0.90	0.10	FALSE
23	GTEx	Brain Nucleus accumbens basal ganglia	CHAF1A	0.31	0.28	lasso	2	0.24	4.0e-07	-5.4	5.4	8.2e-08	0.52	0.34	0.42	FALSE
71	GTEx	Whole Blood	CTB-50L17.9	0.21	0.17	lasso	3	0.18	9.6e-17	-5.3	5.4	8.2e-08	0.50	0.80	0.20	FALSE
60	GTEx	Skin Sun Exposed Lower leg	CTB-50L17.9	0.39	0.48	lasso	3	0.47	7.7e-44	-5.3	5.4	8.4e-08	0.49	0.91	0.09	FALSE
58	GTEx	Skin Sun Exposed Lower leg	CHAF1A	0.19	0.18	lasso	1	0.17	5.1e-14	-5.4	5.4	8.5e-08	0.52	0.80	0.20	FALSE
3	GTEx	Adipose Subcutaneous	CTB-50L17.9	0.29	0.30	lasso	2	0.30	2.3e-24	-5.3	5.4	8.7e-08	0.49	0.90	0.10	FALSE
18	GTEx	Brain Cerebellum	CTB-50L17.5	0.33	0.22	lasso	4	0.20	1.8e-06	-5.3	5.4	8.8e-08	0.50	0.63	0.23	FALSE
26	GTEx	Brain Putamen basal ganglia	CTB-50L17.9	0.33	0.32	lasso	1	0.33	1.2e-08	-5.3	5.3	8.9e-08	0.49	0.28	0.54	FALSE
31	GTEx	Cells EBV-transformed lymphocytes	CTB-50L17.9	0.31	0.27	lasso	1	0.23	3.6e-08	-5.3	5.3	8.9e-08	0.49	0.80	0.14	FALSE
53	GTEx	Nerve Tibial	CTB-50L17.9	0.35	0.41	lasso	1	0.40	2.1e-30	-5.3	5.3	8.9e-08	0.49	0.90	0.10	FALSE
62	GTEx	Stomach	CTB-50L17.9	0.28	0.31	lasso	1	0.31	3.6e-15	-5.3	5.3	8.9e-08	0.49	0.88	0.12	FALSE
68	GTEx	Thyroid	CTB-50L17.9	0.35	0.42	lasso	2	0.42	2.2e-34	-5.3	5.3	8.9e-08	0.49	0.90	0.10	FALSE
78	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UBXN6	0.15	0.10	lasso	1	0.10	2.8e-06	-5.3	5.3	8.9e-08	0.49	0.54	0.19	FALSE
30	GTEx	Breast Mammary Tissue (Female)	CTB-50L17.9	0.45	0.25	lasso	7	0.26	1.6e-08	-5.5	5.3	9.5e-08	0.48	0.47	0.42	FALSE
6	GTEx	Adrenal Gland	CTB-50L17.9	0.38	0.35	lasso	3	0.34	5.8e-13	-5.3	5.3	9.6e-08	0.49	0.89	0.11	FALSE
25	GTEx	Brain Putamen basal ganglia	CHAF1A	0.40	0.34	lasso	4	0.37	1.2e-09	-5.8	5.3	1.1e-07	0.54	0.32	0.39	FALSE
59	GTEx	Skin Sun Exposed Lower leg	UBXN6	0.14	0.00	enet	31	0.00	7.1e-01	6.1	5.3	1.1e-07	0.47	0.03	0.72	FALSE
28	GTEx	Breast Mammary Tissue (Male)	CTB-50L17.9	0.30	0.18	lasso	4	0.10	2.3e-03	-5.3	5.3	1.2e-07	0.48	0.05	0.30	FALSE
61	GTEx	Small Intestine Terminal Ileum	CTB-50L17.9	0.46	0.34	lasso	4	0.36	7.2e-09	-5.3	5.3	1.2e-07	0.49	0.42	0.36	FALSE
50	GTEx	Muscle Skeletal	AC007292.3	0.08	0.03	lasso	3	0.04	1.4e-04	-5.2	-5.3	1.4e-07	-0.49	0.72	0.20	FALSE
4	GTEx	Adipose Visceral Omentum	CTB-50L17.9	0.30	0.23	lasso	4	0.22	2.1e-11	-5.3	5.2	2.0e-07	0.43	0.87	0.13	FALSE
46	GTEx	Muscle Skeletal	MPND	0.10	0.07	lasso	3	0.05	6.3e-06	-5.2	-5.2	2.0e-07	-0.50	0.84	0.15	FALSE
5	GTEx	Adrenal Gland	CHAF1A	0.22	0.18	lasso	3	0.17	1.1e-06	-4.9	5.2	2.4e-07	0.51	0.70	0.10	FALSE
29	GTEx	Breast Mammary Tissue (Female)	CHAF1A	0.33	0.14	lasso	6	0.09	1.6e-03	-5.4	5.2	2.5e-07	0.48	0.34	0.10	FALSE
44	GTEx	Heart Left Ventricle	CTB-50L17.9	0.25	0.17	lasso	2	0.18	5.4e-10	-5.3	5.1	2.8e-07	0.47	0.85	0.14	FALSE
66	GTEx	Testis	CTB-50L17.9	0.39	0.30	enet	36	0.34	9.4e-16	-5.3	5.1	3.0e-07	0.22	0.86	0.14	FALSE
7	GTEx	Artery Aorta	MPND	0.14	0.06	lasso	2	0.03	6.7e-03	-5.0	-5.1	3.1e-07	-0.48	0.22	0.11	FALSE