[Hub]/) : Traits : Impedance of arm (right) : ← →

chr19:6,419,098-11,140,703

Best TWAS P=6.93e-14 · Best GWAS P=3.89e-18 conditioned to 3.91e-25

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
80	The Cancer Genome Atlas	Breast Invasive Carcinoma	OLFM2	0.03	0.04	blup	47	0.04	6.7e-09	-7.26	7.5	6.9e-14	-0.02	0.19	0.81	TRUE
74	ROSMAP	Brain Pre-frontal Cortex	INSR	0.15	0.09	bslmm	487	0.08	6.2e-11	7.35	-7.3	2.3e-13	0.03	0.00	1.00	TRUE
48	GTEx	Lung	EVI5L	0.17	0.10	lasso	7	0.12	7.9e-10	-6.34	-6.6	3.4e-11	0.47	0.97	0.01	TRUE
86	The Cancer Genome Atlas	Glioblastoma Multiforme	ZNF559	0.45	0.02	enet	15	0.07	3.6e-03	-0.29	6.1	1.1e-09	-0.01	0.02	0.46	TRUE
66	GTEx	Testis	MARCH2	0.26	0.22	enet	12	0.22	6.8e-10	-5.79	-5.8	5.0e-09	0.04	0.00	1.00	TRUE
85	The Cancer Genome Atlas	Glioblastoma Multiforme	ZNF266	0.23	0.26	blup	46	0.24	5.2e-08	5.44	-5.8	7.4e-09	0.03	0.03	0.97	TRUE
1	CommonMind	Brain Pre-frontal Cortex	RAVER1	0.06	0.03	bslmm	388	0.04	2.5e-05	5.58	5.6	2.3e-08	-0.02	0.27	0.12	TRUE
15	GTEx	Brain Cerebellar Hemisphere	CTD-2623N2.3	0.12	0.07	enet	30	0.10	1.4e-03	5.42	-5.3	1.0e-07	0.02	0.12	0.05	TRUE
96	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ZNF266	0.09	0.07	enet	14	0.08	8.1e-06	5.46	-5.3	1.3e-07	0.00	0.03	0.97	TRUE
35	GTEx	Colon Sigmoid	ZNF266	0.43	0.63	enet	16	0.62	3.0e-27	5.38	-5.2	2.6e-07	0.01	1.00	0.00	TRUE
100	The Cancer Genome Atlas	Prostate Adenocarcinoma	PIN1	0.04	0.06	blup	27	0.05	7.1e-06	-7.12	-7.4	1.5e-13	0.03	0.08	0.90	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	CTD-2623N2.11	0.21	0.21	lasso	2	0.20	9.0e-26	-7.09	-7.1	1.2e-12	0.06	0.48	0.52	FALSE
45	GTEx	Heart Left Ventricle	ZNF699	0.11	0.09	lasso	3	0.08	7.0e-05	5.47	-6.0	1.9e-09	0.03	0.13	0.79	FALSE
84	The Cancer Genome Atlas	Esophageal Carcinoma	ZNF266	0.16	0.10	blup	50	0.12	1.1e-04	5.44	-5.8	5.6e-09	0.02	0.03	0.93	FALSE
79	The Cancer Genome Atlas	Breast Invasive Carcinoma	MARCH2	0.06	0.06	lasso	3	0.06	7.5e-12	-5.79	-5.8	6.5e-09	0.00	0.00	1.00	FALSE
12	GTEx	Brain Caudate basal ganglia	MARCH2	0.43	0.13	enet	33	0.21	1.2e-06	-5.58	-5.8	6.6e-09	0.00	0.01	0.98	FALSE
50	GTEx	Muscle Skeletal	MARCH2	0.21	0.18	enet	20	0.19	2.7e-18	-5.58	-5.8	7.6e-09	0.00	0.00	1.00	FALSE
32	GTEx	Cells Transformed fibroblasts	MARCH2	0.35	0.27	enet	14	0.35	2.6e-27	-5.58	-5.8	8.1e-09	-0.02	0.01	0.99	FALSE
8	GTEx	Artery Coronary	MARCH2	0.22	0.12	lasso	5	0.16	5.4e-06	-5.30	-5.7	1.0e-08	-0.01	0.01	0.98	FALSE
103	The Cancer Genome Atlas	Soft Tissue Sarcoma	MARCH2	0.06	0.04	lasso	2	0.03	5.4e-03	-5.04	-5.7	1.1e-08	-0.03	0.01	0.88	FALSE
28	GTEx	Breast Mammary Tissue	MARCH2	0.24	0.13	lasso	7	0.11	4.6e-06	-5.79	-5.7	1.3e-08	0.00	0.00	1.00	FALSE
55	GTEx	Pancreas	MARCH2	0.19	0.09	lasso	3	0.08	2.8e-04	-5.42	-5.7	1.4e-08	0.00	0.01	0.98	FALSE
82	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	MARCH2	0.08	0.06	lasso	5	0.06	5.5e-04	-5.58	-5.7	1.4e-08	-0.01	0.01	0.98	FALSE
83	The Cancer Genome Atlas	Colon Adenocarcinoma	MARCH2	0.08	0.11	blup	42	0.08	1.4e-05	-4.93	-5.7	1.5e-08	-0.05	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	MARCH2	0.30	0.30	lasso	6	0.31	5.9e-26	-5.58	-5.6	1.7e-08	-0.01	0.01	0.99	FALSE
16	GTEx	Brain Cerebellum	MARCH2	0.35	0.22	lasso	5	0.19	2.9e-06	-5.58	-5.6	1.9e-08	-0.01	0.00	0.99	FALSE
68	GTEx	Thyroid	EVI5L	0.11	0.11	lasso	2	0.09	1.1e-07	-5.48	-5.6	2.0e-08	0.51	0.97	0.02	FALSE
99	The Cancer Genome Atlas	Prostate Adenocarcinoma	MARCH2	0.12	0.15	lasso	4	0.15	6.9e-16	-5.58	-5.6	2.1e-08	-0.01	0.01	0.99	FALSE
102	The Cancer Genome Atlas	Rectum Adenocarcinoma	ZNF266	0.26	0.13	enet	13	0.15	2.7e-04	5.59	-5.6	2.1e-08	0.02	0.02	0.71	FALSE
7	GTEx	Artery Aorta	MARCH2	0.52	0.46	lasso	5	0.50	2.0e-31	-5.58	-5.6	2.2e-08	-0.01	0.01	0.99	FALSE
60	GTEx	Skin Not Sun Exposed Suprapubic	MARCH2	0.42	0.33	enet	27	0.35	5.6e-20	-5.42	-5.6	2.3e-08	-0.03	0.00	1.00	FALSE
71	GTEx	Vagina	ZNF266	0.44	0.50	enet	18	0.51	1.4e-13	5.43	-5.6	2.7e-08	0.02	1.00	0.00	FALSE
39	GTEx	Esophagus Muscularis	MARCH2	0.34	0.30	enet	22	0.32	6.9e-20	-5.79	-5.6	2.8e-08	-0.01	0.00	1.00	FALSE
49	GTEx	Lung	ZNF266	0.40	0.63	enet	26	0.63	5.1e-61	5.44	-5.5	2.9e-08	0.02	1.00	0.00	FALSE
62	GTEx	Skin Sun Exposed Lower leg	MARCH2	0.33	0.33	lasso	6	0.34	4.1e-29	-5.58	-5.5	3.0e-08	-0.02	0.01	0.99	FALSE
30	GTEx	Breast Mammary Tissue (Female)	MARCH2	0.26	0.14	lasso	6	0.11	3.3e-04	-5.79	-5.5	3.4e-08	-0.01	0.00	0.99	FALSE
22	GTEx	Brain Hypothalamus	ZNF266	0.35	0.32	lasso	9	0.33	1.9e-08	5.47	-5.5	3.5e-08	0.02	0.93	0.04	FALSE
37	GTEx	Esophagus Gastroesophageal Junction	ZNF266	0.48	0.61	lasso	4	0.61	2.7e-27	5.38	-5.5	3.5e-08	0.02	1.00	0.00	FALSE
73	NTR	Blood	MARCH2	0.05	0.06	lasso	4	0.06	1.0e-18	-5.04	-5.5	3.5e-08	-0.01	0.03	0.97	FALSE
26	GTEx	Brain Putamen basal ganglia	ZNF266	0.40	0.41	enet	14	0.40	1.7e-10	5.47	-5.5	3.6e-08	0.02	0.99	0.00	FALSE
72	GTEx	Whole Blood	ZNF266	0.28	0.23	lasso	3	0.22	8.1e-20	5.46	-5.5	3.6e-08	0.02	1.00	0.00	FALSE
97	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ZNF266	0.35	0.41	lasso	11	0.41	1.1e-18	5.44	-5.5	3.8e-08	0.02	0.03	0.97	FALSE
104	The Cancer Genome Atlas	Soft Tissue Sarcoma	ZNF266	0.11	0.14	lasso	11	0.13	4.0e-08	5.43	-5.5	3.9e-08	0.02	0.03	0.97	FALSE
20	GTEx	Brain Frontal Cortex BA9	MARCH2	0.48	0.13	lasso	10	0.14	1.2e-04	-5.79	-5.5	4.0e-08	-0.03	0.00	0.98	FALSE
64	GTEx	Spleen	ZNF266	0.74	0.62	lasso	9	0.60	6.5e-19	5.46	-5.5	4.0e-08	0.02	1.00	0.00	FALSE
59	GTEx	Prostate	ZNF266	0.49	0.54	lasso	7	0.56	1.2e-16	5.44	-5.5	4.1e-08	0.02	1.00	0.00	FALSE
14	GTEx	Brain Cerebellar Hemisphere	ZNF266	0.44	0.60	lasso	11	0.58	3.5e-18	5.44	-5.5	4.2e-08	0.02	1.00	0.00	FALSE
13	GTEx	Brain Caudate basal ganglia	ZNF266	0.33	0.49	lasso	5	0.47	4.3e-15	5.47	-5.5	4.4e-08	0.02	1.00	0.00	FALSE
61	GTEx	Skin Not Sun Exposed Suprapubic	ZNF266	0.29	0.42	lasso	5	0.42	4.3e-25	5.44	-5.5	4.4e-08	0.02	1.00	0.00	FALSE
6	GTEx	Adrenal Gland	ZNF266	0.40	0.58	enet	19	0.59	1.6e-25	5.41	-5.5	4.5e-08	0.02	1.00	0.00	FALSE
107	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF266	0.25	0.51	enet	22	0.52	3.4e-59	5.41	-5.5	4.5e-08	0.02	0.03	0.96	FALSE
24	GTEx	Brain Nucleus accumbens basal ganglia	ZNF266	0.34	0.43	enet	13	0.32	2.8e-09	5.43	-5.5	4.6e-08	0.02	1.00	0.00	FALSE
67	GTEx	Testis	ZNF266	0.55	0.61	lasso	8	0.61	3.5e-33	5.44	-5.5	4.6e-08	0.02	1.00	0.00	FALSE
95	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MARCH2	0.08	0.10	enet	5	0.10	2.6e-11	-5.58	-5.5	4.6e-08	0.00	0.00	1.00	FALSE
23	GTEx	Brain Nucleus accumbens basal ganglia	MARCH2	0.30	0.21	lasso	5	0.28	3.9e-08	-5.04	-5.5	4.7e-08	-0.01	0.01	0.98	FALSE
19	GTEx	Brain Cortex	ZNF266	0.38	0.39	enet	15	0.48	5.4e-15	5.44	-5.5	4.8e-08	0.02	1.00	0.00	FALSE
92	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNAPC2	0.03	0.00	blup	42	0.01	9.4e-03	-6.77	-5.5	4.9e-08	0.63	0.01	0.71	FALSE
18	GTEx	Brain Cerebellum	ZNF266	0.46	0.62	enet	11	0.59	2.1e-21	5.44	-5.5	5.0e-08	0.02	1.00	0.00	FALSE
77	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	MARCH2	0.07	0.07	blup	42	0.08	1.4e-07	-4.54	-5.4	5.0e-08	-0.02	0.05	0.95	FALSE
94	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ZNF266	0.10	0.11	enet	12	0.12	4.6e-06	5.38	-5.4	5.1e-08	0.01	0.03	0.97	FALSE
33	GTEx	Cells Transformed fibroblasts	ZNF266	0.44	0.62	lasso	1	0.61	1.4e-57	5.44	-5.4	5.2e-08	0.02	1.00	0.00	FALSE
54	GTEx	Ovary	ZNF266	0.47	0.57	lasso	4	0.56	1.7e-16	5.43	-5.4	5.2e-08	0.01	1.00	0.00	FALSE
56	GTEx	Pancreas	ZNF266	0.48	0.58	lasso	2	0.60	6.2e-31	5.44	-5.4	5.2e-08	0.02	1.00	0.00	FALSE
105	The Cancer Genome Atlas	Stomach Adenocarcinoma	MARCH2	0.09	0.10	blup	42	0.10	6.1e-08	-5.79	-5.4	5.2e-08	0.00	0.00	1.00	FALSE
11	GTEx	Artery Tibial	ZNF266	0.46	0.68	lasso	7	0.68	1.3e-71	5.41	-5.4	5.3e-08	0.02	1.00	0.00	FALSE
70	GTEx	Uterus	ZNF266	0.40	0.48	lasso	9	0.47	5.1e-11	5.44	-5.4	5.3e-08	0.02	0.98	0.00	FALSE
57	GTEx	Pituitary	ZNF266	0.37	0.45	lasso	2	0.43	5.1e-12	5.44	-5.4	5.4e-08	0.02	1.00	0.00	FALSE
65	GTEx	Stomach	ZNF266	0.42	0.52	lasso	7	0.51	4.0e-28	5.44	-5.4	5.4e-08	0.02	1.00	0.00	FALSE
81	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZNF266	0.10	0.20	lasso	2	0.19	2.6e-38	5.44	-5.4	5.4e-08	0.02	0.04	0.96	FALSE
98	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ZNF266	0.23	0.34	lasso	1	0.33	1.2e-13	5.44	-5.4	5.4e-08	0.02	0.03	0.97	FALSE
21	GTEx	Brain Hippocampus	ZNF266	0.29	0.37	lasso	11	0.36	2.2e-09	5.43	-5.4	5.5e-08	0.02	0.98	0.00	FALSE
93	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF266	0.27	0.47	lasso	12	0.49	4.9e-64	5.44	-5.4	5.5e-08	0.02	0.03	0.97	FALSE
44	GTEx	Heart Left Ventricle	ZNF266	0.25	0.39	lasso	5	0.38	1.2e-21	5.38	-5.4	5.7e-08	0.02	1.00	0.00	FALSE
47	GTEx	Lung	MARCH2	0.36	0.25	lasso	8	0.29	2.8e-22	-5.58	-5.4	5.8e-08	-0.02	0.00	1.00	FALSE
10	GTEx	Artery Tibial	MARCH2	0.36	0.37	lasso	5	0.44	5.0e-37	-4.93	-5.4	5.9e-08	-0.02	0.01	0.99	FALSE
9	GTEx	Artery Coronary	ZNF266	0.43	0.50	lasso	24	0.49	7.5e-19	5.38	-5.4	6.0e-08	0.01	1.00	0.00	FALSE
43	GTEx	Heart Left Ventricle	MARCH2	0.36	0.26	enet	21	0.28	3.3e-15	-5.42	-5.4	6.1e-08	-0.01	0.00	1.00	FALSE
63	GTEx	Skin Sun Exposed Lower leg	ZNF266	0.42	0.62	lasso	5	0.62	3.4e-65	5.44	-5.4	6.1e-08	0.02	1.00	0.00	FALSE
40	GTEx	Esophagus Muscularis	ZNF266	0.42	0.55	lasso	2	0.56	5.8e-41	5.38	-5.4	6.4e-08	0.02	1.00	0.00	FALSE
69	GTEx	Thyroid	ZNF266	0.45	0.67	lasso	8	0.69	1.5e-71	5.44	-5.4	6.4e-08	0.02	1.00	0.00	FALSE
17	GTEx	Brain Cerebellum	EVI5L	0.27	-0.01	lasso	5	0.00	3.1e-01	-5.80	-5.4	6.5e-08	0.48	0.12	0.05	FALSE
89	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF266	0.19	0.28	lasso	5	0.28	5.3e-31	5.44	-5.4	6.5e-08	0.02	0.03	0.97	FALSE
78	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ZNF266	0.20	0.32	enet	11	0.32	8.0e-28	5.46	-5.4	6.6e-08	0.02	0.03	0.97	FALSE
88	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MARCH2	0.08	0.08	enet	14	0.08	1.2e-09	-4.93	-5.4	6.8e-08	-0.04	0.01	0.99	FALSE
42	GTEx	Heart Atrial Appendage	ZNF266	0.28	0.45	enet	19	0.46	4.2e-23	5.38	-5.4	7.0e-08	0.01	1.00	0.00	FALSE
31	GTEx	Cells EBV-transformed lymphocytes	ZNF266	0.60	0.74	enet	19	0.74	4.1e-34	5.44	-5.4	7.6e-08	0.01	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	MARCH2	0.27	0.17	lasso	4	0.15	4.0e-08	-5.42	-5.4	7.7e-08	0.00	0.01	0.99	FALSE
51	GTEx	Muscle Skeletal	ZNF266	0.29	0.50	lasso	12	0.50	8.8e-56	5.46	-5.4	8.1e-08	0.02	1.00	0.00	FALSE
34	GTEx	Colon Sigmoid	MARCH2	0.33	0.14	lasso	7	0.25	2.4e-09	-4.93	-5.3	8.8e-08	-0.04	0.00	1.00	FALSE
29	GTEx	Breast Mammary Tissue	ZNF266	0.41	0.56	lasso	9	0.57	2.9e-35	5.43	-5.3	9.0e-08	0.02	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	ZNF266	0.43	0.61	lasso	9	0.62	2.0e-63	5.44	-5.3	9.8e-08	0.02	1.00	0.00	FALSE
91	The Cancer Genome Atlas	Brain Lower Grade Glioma	MARCH2	0.10	0.10	enet	9	0.12	1.9e-13	-4.54	-5.3	1.1e-07	-0.02	0.01	0.99	FALSE
108	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ZNF266	0.25	0.39	enet	27	0.32	1.2e-09	5.46	-5.3	1.1e-07	0.02	0.03	0.97	FALSE
25	GTEx	Brain Putamen basal ganglia	MARCH2	0.52	0.25	lasso	10	0.37	9.0e-10	-5.58	-5.3	1.3e-07	-0.03	0.01	0.98	FALSE
58	GTEx	Prostate	MARCH2	0.66	0.20	lasso	9	0.19	1.4e-05	-5.04	-5.3	1.4e-07	0.01	0.02	0.94	FALSE
36	GTEx	Colon Transverse	ZNF266	0.47	0.63	lasso	8	0.63	1.8e-37	5.38	-5.2	1.5e-07	0.01	1.00	0.00	FALSE
53	GTEx	Nerve Tibial	ZNF266	0.53	0.68	enet	20	0.68	2.5e-64	5.44	-5.2	1.6e-07	0.02	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	ZNF266	0.48	0.59	lasso	11	0.61	2.4e-39	5.46	-5.2	1.8e-07	0.01	1.00	0.00	FALSE
90	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ZNF266	0.14	0.21	enet	25	0.19	2.9e-11	5.45	-5.2	1.8e-07	0.01	0.03	0.97	FALSE
106	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ZNF266	0.47	0.35	lasso	7	0.37	6.5e-14	5.44	-5.2	1.8e-07	0.02	0.03	0.97	FALSE
38	GTEx	Esophagus Mucosa	ZNF266	0.46	0.65	enet	22	0.64	1.2e-55	5.41	-5.2	1.9e-07	0.01	1.00	0.00	FALSE
87	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZNF266	0.11	0.17	blup	45	0.17	1.4e-18	5.59	-5.2	1.9e-07	0.02	0.02	0.98	FALSE
46	GTEx	Liver	ZNF266	0.31	0.23	lasso	16	0.22	7.3e-07	5.38	-5.2	2.0e-07	0.00	0.91	0.03	FALSE
52	GTEx	Nerve Tibial	MARCH2	0.31	0.32	lasso	5	0.35	1.3e-25	-5.30	-5.2	2.0e-07	0.00	0.02	0.98	FALSE
41	GTEx	Heart Atrial Appendage	MARCH2	0.26	0.18	enet	36	0.21	1.2e-09	-5.42	-5.2	2.4e-07	-0.01	0.00	1.00	FALSE
101	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZNF266	0.32	0.55	enet	21	0.57	8.0e-72	5.44	-5.1	2.7e-07	0.01	0.04	0.96	FALSE
27	GTEx	Breast Mammary Tissue	XAB2	0.25	0.16	lasso	4	0.15	2.6e-08	-3.50	5.1	2.9e-07	-0.24	0.99	0.00	FALSE
75	ROSMAP	Brain Pre-frontal Cortex	ZNF266	0.42	0.65	lasso	9	0.66	2.2e-115	5.44	-5.1	2.9e-07	0.01	1.00	0.00	FALSE