[Hub]/) : Traits : Impedance of arm (right) :

chr19:6,419,098-11,140,703

Best TWAS P=6.93e-14 · Best GWAS P=3.89e-18 conditioned to 3.91e-25

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAVER1 0.06 0.03 bslmm 388 0.04 2.5e-05 5.58 5.6 2.3e-08 -0.02 0.27 0.12 TRUE
2 GTEx Adipose Subcutaneous MARCH2 0.30 0.30 lasso 6 0.31 5.9e-26 -5.58 -5.6 1.7e-08 -0.01 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous ZNF266 0.43 0.61 lasso 9 0.62 2.0e-63 5.44 -5.3 9.8e-08 0.02 1.00 0.00 FALSE
4 GTEx Adipose Visceral Omentum MARCH2 0.27 0.17 lasso 4 0.15 4.0e-08 -5.42 -5.4 7.7e-08 0.00 0.01 0.99 FALSE
5 GTEx Adipose Visceral Omentum ZNF266 0.48 0.59 lasso 11 0.61 2.4e-39 5.46 -5.2 1.8e-07 0.01 1.00 0.00 FALSE
6 GTEx Adrenal Gland ZNF266 0.40 0.58 enet 19 0.59 1.6e-25 5.41 -5.5 4.5e-08 0.02 1.00 0.00 FALSE
7 GTEx Artery Aorta MARCH2 0.52 0.46 lasso 5 0.50 2.0e-31 -5.58 -5.6 2.2e-08 -0.01 0.01 0.99 FALSE
8 GTEx Artery Coronary MARCH2 0.22 0.12 lasso 5 0.16 5.4e-06 -5.30 -5.7 1.0e-08 -0.01 0.01 0.98 FALSE
9 GTEx Artery Coronary ZNF266 0.43 0.50 lasso 24 0.49 7.5e-19 5.38 -5.4 6.0e-08 0.01 1.00 0.00 FALSE
10 GTEx Artery Tibial MARCH2 0.36 0.37 lasso 5 0.44 5.0e-37 -4.93 -5.4 5.9e-08 -0.02 0.01 0.99 FALSE
11 GTEx Artery Tibial ZNF266 0.46 0.68 lasso 7 0.68 1.3e-71 5.41 -5.4 5.3e-08 0.02 1.00 0.00 FALSE
12 GTEx Brain Caudate basal ganglia MARCH2 0.43 0.13 enet 33 0.21 1.2e-06 -5.58 -5.8 6.6e-09 0.00 0.01 0.98 FALSE
13 GTEx Brain Caudate basal ganglia ZNF266 0.33 0.49 lasso 5 0.47 4.3e-15 5.47 -5.5 4.4e-08 0.02 1.00 0.00 FALSE
14 GTEx Brain Cerebellar Hemisphere ZNF266 0.44 0.60 lasso 11 0.58 3.5e-18 5.44 -5.5 4.2e-08 0.02 1.00 0.00 FALSE
15 GTEx Brain Cerebellar Hemisphere CTD-2623N2.3 0.12 0.07 enet 30 0.10 1.4e-03 5.42 -5.3 1.0e-07 0.02 0.12 0.05 TRUE
16 GTEx Brain Cerebellum MARCH2 0.35 0.22 lasso 5 0.19 2.9e-06 -5.58 -5.6 1.9e-08 -0.01 0.00 0.99 FALSE
17 GTEx Brain Cerebellum EVI5L 0.27 -0.01 lasso 5 0.00 3.1e-01 -5.80 -5.4 6.5e-08 0.48 0.12 0.05 FALSE
18 GTEx Brain Cerebellum ZNF266 0.46 0.62 enet 11 0.59 2.1e-21 5.44 -5.5 5.0e-08 0.02 1.00 0.00 FALSE
19 GTEx Brain Cortex ZNF266 0.38 0.39 enet 15 0.48 5.4e-15 5.44 -5.5 4.8e-08 0.02 1.00 0.00 FALSE
20 GTEx Brain Frontal Cortex BA9 MARCH2 0.48 0.13 lasso 10 0.14 1.2e-04 -5.79 -5.5 4.0e-08 -0.03 0.00 0.98 FALSE
21 GTEx Brain Hippocampus ZNF266 0.29 0.37 lasso 11 0.36 2.2e-09 5.43 -5.4 5.5e-08 0.02 0.98 0.00 FALSE
22 GTEx Brain Hypothalamus ZNF266 0.35 0.32 lasso 9 0.33 1.9e-08 5.47 -5.5 3.5e-08 0.02 0.93 0.04 FALSE
23 GTEx Brain Nucleus accumbens basal ganglia MARCH2 0.30 0.21 lasso 5 0.28 3.9e-08 -5.04 -5.5 4.7e-08 -0.01 0.01 0.98 FALSE
24 GTEx Brain Nucleus accumbens basal ganglia ZNF266 0.34 0.43 enet 13 0.32 2.8e-09 5.43 -5.5 4.6e-08 0.02 1.00 0.00 FALSE
25 GTEx Brain Putamen basal ganglia MARCH2 0.52 0.25 lasso 10 0.37 9.0e-10 -5.58 -5.3 1.3e-07 -0.03 0.01 0.98 FALSE
26 GTEx Brain Putamen basal ganglia ZNF266 0.40 0.41 enet 14 0.40 1.7e-10 5.47 -5.5 3.6e-08 0.02 0.99 0.00 FALSE
27 GTEx Breast Mammary Tissue XAB2 0.25 0.16 lasso 4 0.15 2.6e-08 -3.50 5.1 2.9e-07 -0.24 0.99 0.00 FALSE
28 GTEx Breast Mammary Tissue MARCH2 0.24 0.13 lasso 7 0.11 4.6e-06 -5.79 -5.7 1.3e-08 0.00 0.00 1.00 FALSE
29 GTEx Breast Mammary Tissue ZNF266 0.41 0.56 lasso 9 0.57 2.9e-35 5.43 -5.3 9.0e-08 0.02 1.00 0.00 FALSE
30 GTEx Breast Mammary Tissue (Female) MARCH2 0.26 0.14 lasso 6 0.11 3.3e-04 -5.79 -5.5 3.4e-08 -0.01 0.00 0.99 FALSE
31 GTEx Cells EBV-transformed lymphocytes ZNF266 0.60 0.74 enet 19 0.74 4.1e-34 5.44 -5.4 7.6e-08 0.01 1.00 0.00 FALSE
32 GTEx Cells Transformed fibroblasts MARCH2 0.35 0.27 enet 14 0.35 2.6e-27 -5.58 -5.8 8.1e-09 -0.02 0.01 0.99 FALSE
33 GTEx Cells Transformed fibroblasts ZNF266 0.44 0.62 lasso 1 0.61 1.4e-57 5.44 -5.4 5.2e-08 0.02 1.00 0.00 FALSE
34 GTEx Colon Sigmoid MARCH2 0.33 0.14 lasso 7 0.25 2.4e-09 -4.93 -5.3 8.8e-08 -0.04 0.00 1.00 FALSE
35 GTEx Colon Sigmoid ZNF266 0.43 0.63 enet 16 0.62 3.0e-27 5.38 -5.2 2.6e-07 0.01 1.00 0.00 TRUE
36 GTEx Colon Transverse ZNF266 0.47 0.63 lasso 8 0.63 1.8e-37 5.38 -5.2 1.5e-07 0.01 1.00 0.00 FALSE
37 GTEx Esophagus Gastroesophageal Junction ZNF266 0.48 0.61 lasso 4 0.61 2.7e-27 5.38 -5.5 3.5e-08 0.02 1.00 0.00 FALSE
38 GTEx Esophagus Mucosa ZNF266 0.46 0.65 enet 22 0.64 1.2e-55 5.41 -5.2 1.9e-07 0.01 1.00 0.00 FALSE
39 GTEx Esophagus Muscularis MARCH2 0.34 0.30 enet 22 0.32 6.9e-20 -5.79 -5.6 2.8e-08 -0.01 0.00 1.00 FALSE
40 GTEx Esophagus Muscularis ZNF266 0.42 0.55 lasso 2 0.56 5.8e-41 5.38 -5.4 6.4e-08 0.02 1.00 0.00 FALSE
41 GTEx Heart Atrial Appendage MARCH2 0.26 0.18 enet 36 0.21 1.2e-09 -5.42 -5.2 2.4e-07 -0.01 0.00 1.00 FALSE
42 GTEx Heart Atrial Appendage ZNF266 0.28 0.45 enet 19 0.46 4.2e-23 5.38 -5.4 7.0e-08 0.01 1.00 0.00 FALSE
43 GTEx Heart Left Ventricle MARCH2 0.36 0.26 enet 21 0.28 3.3e-15 -5.42 -5.4 6.1e-08 -0.01 0.00 1.00 FALSE
44 GTEx Heart Left Ventricle ZNF266 0.25 0.39 lasso 5 0.38 1.2e-21 5.38 -5.4 5.7e-08 0.02 1.00 0.00 FALSE
45 GTEx Heart Left Ventricle ZNF699 0.11 0.09 lasso 3 0.08 7.0e-05 5.47 -6.0 1.9e-09 0.03 0.13 0.79 FALSE
46 GTEx Liver ZNF266 0.31 0.23 lasso 16 0.22 7.3e-07 5.38 -5.2 2.0e-07 0.00 0.91 0.03 FALSE
47 GTEx Lung MARCH2 0.36 0.25 lasso 8 0.29 2.8e-22 -5.58 -5.4 5.8e-08 -0.02 0.00 1.00 FALSE
48 GTEx Lung EVI5L 0.17 0.10 lasso 7 0.12 7.9e-10 -6.34 -6.6 3.4e-11 0.47 0.97 0.01 TRUE
49 GTEx Lung ZNF266 0.40 0.63 enet 26 0.63 5.1e-61 5.44 -5.5 2.9e-08 0.02 1.00 0.00 FALSE
50 GTEx Muscle Skeletal MARCH2 0.21 0.18 enet 20 0.19 2.7e-18 -5.58 -5.8 7.6e-09 0.00 0.00 1.00 FALSE
51 GTEx Muscle Skeletal ZNF266 0.29 0.50 lasso 12 0.50 8.8e-56 5.46 -5.4 8.1e-08 0.02 1.00 0.00 FALSE
52 GTEx Nerve Tibial MARCH2 0.31 0.32 lasso 5 0.35 1.3e-25 -5.30 -5.2 2.0e-07 0.00 0.02 0.98 FALSE
53 GTEx Nerve Tibial ZNF266 0.53 0.68 enet 20 0.68 2.5e-64 5.44 -5.2 1.6e-07 0.02 1.00 0.00 FALSE
54 GTEx Ovary ZNF266 0.47 0.57 lasso 4 0.56 1.7e-16 5.43 -5.4 5.2e-08 0.01 1.00 0.00 FALSE
55 GTEx Pancreas MARCH2 0.19 0.09 lasso 3 0.08 2.8e-04 -5.42 -5.7 1.4e-08 0.00 0.01 0.98 FALSE
56 GTEx Pancreas ZNF266 0.48 0.58 lasso 2 0.60 6.2e-31 5.44 -5.4 5.2e-08 0.02 1.00 0.00 FALSE
57 GTEx Pituitary ZNF266 0.37 0.45 lasso 2 0.43 5.1e-12 5.44 -5.4 5.4e-08 0.02 1.00 0.00 FALSE
58 GTEx Prostate MARCH2 0.66 0.20 lasso 9 0.19 1.4e-05 -5.04 -5.3 1.4e-07 0.01 0.02 0.94 FALSE
59 GTEx Prostate ZNF266 0.49 0.54 lasso 7 0.56 1.2e-16 5.44 -5.5 4.1e-08 0.02 1.00 0.00 FALSE
60 GTEx Skin Not Sun Exposed Suprapubic MARCH2 0.42 0.33 enet 27 0.35 5.6e-20 -5.42 -5.6 2.3e-08 -0.03 0.00 1.00 FALSE
61 GTEx Skin Not Sun Exposed Suprapubic ZNF266 0.29 0.42 lasso 5 0.42 4.3e-25 5.44 -5.5 4.4e-08 0.02 1.00 0.00 FALSE
62 GTEx Skin Sun Exposed Lower leg MARCH2 0.33 0.33 lasso 6 0.34 4.1e-29 -5.58 -5.5 3.0e-08 -0.02 0.01 0.99 FALSE
63 GTEx Skin Sun Exposed Lower leg ZNF266 0.42 0.62 lasso 5 0.62 3.4e-65 5.44 -5.4 6.1e-08 0.02 1.00 0.00 FALSE
64 GTEx Spleen ZNF266 0.74 0.62 lasso 9 0.60 6.5e-19 5.46 -5.5 4.0e-08 0.02 1.00 0.00 FALSE
65 GTEx Stomach ZNF266 0.42 0.52 lasso 7 0.51 4.0e-28 5.44 -5.4 5.4e-08 0.02 1.00 0.00 FALSE
66 GTEx Testis MARCH2 0.26 0.22 enet 12 0.22 6.8e-10 -5.79 -5.8 5.0e-09 0.04 0.00 1.00 TRUE
67 GTEx Testis ZNF266 0.55 0.61 lasso 8 0.61 3.5e-33 5.44 -5.5 4.6e-08 0.02 1.00 0.00 FALSE
68 GTEx Thyroid EVI5L 0.11 0.11 lasso 2 0.09 1.1e-07 -5.48 -5.6 2.0e-08 0.51 0.97 0.02 FALSE
69 GTEx Thyroid ZNF266 0.45 0.67 lasso 8 0.69 1.5e-71 5.44 -5.4 6.4e-08 0.02 1.00 0.00 FALSE
70 GTEx Uterus ZNF266 0.40 0.48 lasso 9 0.47 5.1e-11 5.44 -5.4 5.3e-08 0.02 0.98 0.00 FALSE
71 GTEx Vagina ZNF266 0.44 0.50 enet 18 0.51 1.4e-13 5.43 -5.6 2.7e-08 0.02 1.00 0.00 FALSE
72 GTEx Whole Blood ZNF266 0.28 0.23 lasso 3 0.22 8.1e-20 5.46 -5.5 3.6e-08 0.02 1.00 0.00 FALSE
73 NTR Blood MARCH2 0.05 0.06 lasso 4 0.06 1.0e-18 -5.04 -5.5 3.5e-08 -0.01 0.03 0.97 FALSE
74 ROSMAP Brain Pre-frontal Cortex INSR 0.15 0.09 bslmm 487 0.08 6.2e-11 7.35 -7.3 2.3e-13 0.03 0.00 1.00 TRUE
75 ROSMAP Brain Pre-frontal Cortex ZNF266 0.42 0.65 lasso 9 0.66 2.2e-115 5.44 -5.1 2.9e-07 0.01 1.00 0.00 FALSE
76 ROSMAP Brain Pre-frontal Cortex CTD-2623N2.11 0.21 0.21 lasso 2 0.20 9.0e-26 -7.09 -7.1 1.2e-12 0.06 0.48 0.52 FALSE
77 The Cancer Genome Atlas Bladder Urothelial Carcinoma MARCH2 0.07 0.07 blup 42 0.08 1.4e-07 -4.54 -5.4 5.0e-08 -0.02 0.05 0.95 FALSE
78 The Cancer Genome Atlas Bladder Urothelial Carcinoma ZNF266 0.20 0.32 enet 11 0.32 8.0e-28 5.46 -5.4 6.6e-08 0.02 0.03 0.97 FALSE
79 The Cancer Genome Atlas Breast Invasive Carcinoma MARCH2 0.06 0.06 lasso 3 0.06 7.5e-12 -5.79 -5.8 6.5e-09 0.00 0.00 1.00 FALSE
80 The Cancer Genome Atlas Breast Invasive Carcinoma OLFM2 0.03 0.04 blup 47 0.04 6.7e-09 -7.26 7.5 6.9e-14 -0.02 0.19 0.81 TRUE
81 The Cancer Genome Atlas Breast Invasive Carcinoma ZNF266 0.10 0.20 lasso 2 0.19 2.6e-38 5.44 -5.4 5.4e-08 0.02 0.04 0.96 FALSE
82 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma MARCH2 0.08 0.06 lasso 5 0.06 5.5e-04 -5.58 -5.7 1.4e-08 -0.01 0.01 0.98 FALSE
83 The Cancer Genome Atlas Colon Adenocarcinoma MARCH2 0.08 0.11 blup 42 0.08 1.4e-05 -4.93 -5.7 1.5e-08 -0.05 0.02 0.98 FALSE
84 The Cancer Genome Atlas Esophageal Carcinoma ZNF266 0.16 0.10 blup 50 0.12 1.1e-04 5.44 -5.8 5.6e-09 0.02 0.03 0.93 FALSE
85 The Cancer Genome Atlas Glioblastoma Multiforme ZNF266 0.23 0.26 blup 46 0.24 5.2e-08 5.44 -5.8 7.4e-09 0.03 0.03 0.97 TRUE
86 The Cancer Genome Atlas Glioblastoma Multiforme ZNF559 0.45 0.02 enet 15 0.07 3.6e-03 -0.29 6.1 1.1e-09 -0.01 0.02 0.46 TRUE
87 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZNF266 0.11 0.17 blup 45 0.17 1.4e-18 5.59 -5.2 1.9e-07 0.02 0.02 0.98 FALSE
88 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MARCH2 0.08 0.08 enet 14 0.08 1.2e-09 -4.93 -5.4 6.8e-08 -0.04 0.01 0.99 FALSE
89 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF266 0.19 0.28 lasso 5 0.28 5.3e-31 5.44 -5.4 6.5e-08 0.02 0.03 0.97 FALSE
90 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ZNF266 0.14 0.21 enet 25 0.19 2.9e-11 5.45 -5.2 1.8e-07 0.01 0.03 0.97 FALSE
91 The Cancer Genome Atlas Brain Lower Grade Glioma MARCH2 0.10 0.10 enet 9 0.12 1.9e-13 -4.54 -5.3 1.1e-07 -0.02 0.01 0.99 FALSE
92 The Cancer Genome Atlas Brain Lower Grade Glioma SNAPC2 0.03 0.00 blup 42 0.01 9.4e-03 -6.77 -5.5 4.9e-08 0.63 0.01 0.71 FALSE
93 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF266 0.27 0.47 lasso 12 0.49 4.9e-64 5.44 -5.4 5.5e-08 0.02 0.03 0.97 FALSE
94 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ZNF266 0.10 0.11 enet 12 0.12 4.6e-06 5.38 -5.4 5.1e-08 0.01 0.03 0.97 FALSE
95 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MARCH2 0.08 0.10 enet 5 0.10 2.6e-11 -5.58 -5.5 4.6e-08 0.00 0.00 1.00 FALSE
96 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ZNF266 0.09 0.07 enet 14 0.08 8.1e-06 5.46 -5.3 1.3e-07 0.00 0.03 0.97 TRUE
97 The Cancer Genome Atlas Pancreatic Adenocarcinoma ZNF266 0.35 0.41 lasso 11 0.41 1.1e-18 5.44 -5.5 3.8e-08 0.02 0.03 0.97 FALSE
98 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ZNF266 0.23 0.34 lasso 1 0.33 1.2e-13 5.44 -5.4 5.4e-08 0.02 0.03 0.97 FALSE
99 The Cancer Genome Atlas Prostate Adenocarcinoma MARCH2 0.12 0.15 lasso 4 0.15 6.9e-16 -5.58 -5.6 2.1e-08 -0.01 0.01 0.99 FALSE
100 The Cancer Genome Atlas Prostate Adenocarcinoma PIN1 0.04 0.06 blup 27 0.05 7.1e-06 -7.12 -7.4 1.5e-13 0.03 0.08 0.90 FALSE
101 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF266 0.32 0.55 enet 21 0.57 8.0e-72 5.44 -5.1 2.7e-07 0.01 0.04 0.96 FALSE
102 The Cancer Genome Atlas Rectum Adenocarcinoma ZNF266 0.26 0.13 enet 13 0.15 2.7e-04 5.59 -5.6 2.1e-08 0.02 0.02 0.71 FALSE
103 The Cancer Genome Atlas Soft Tissue Sarcoma MARCH2 0.06 0.04 lasso 2 0.03 5.4e-03 -5.04 -5.7 1.1e-08 -0.03 0.01 0.88 FALSE
104 The Cancer Genome Atlas Soft Tissue Sarcoma ZNF266 0.11 0.14 lasso 11 0.13 4.0e-08 5.43 -5.5 3.9e-08 0.02 0.03 0.97 FALSE
105 The Cancer Genome Atlas Stomach Adenocarcinoma MARCH2 0.09 0.10 blup 42 0.10 6.1e-08 -5.79 -5.4 5.2e-08 0.00 0.00 1.00 FALSE
106 The Cancer Genome Atlas Testicular Germ Cell Tumors ZNF266 0.47 0.35 lasso 7 0.37 6.5e-14 5.44 -5.2 1.8e-07 0.02 0.03 0.97 FALSE
107 The Cancer Genome Atlas Thyroid Carcinoma ZNF266 0.25 0.51 enet 22 0.52 3.4e-59 5.41 -5.5 4.5e-08 0.02 0.03 0.96 FALSE
108 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma ZNF266 0.25 0.39 enet 27 0.32 1.2e-09 5.46 -5.3 1.1e-07 0.02 0.03 0.97 FALSE