Best TWAS P=5.79e-10 · Best GWAS P=3.82e-19 conditioned to 8.24e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PEPD | 0.32 | 0.27 | enet | 22 | 0.38 | 1.2e-49 | 4.8 | 5.6 | 1.9e-08 | -0.54 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Artery Tibial | CEBPG | 0.14 | 0.04 | lasso | 3 | 0.02 | 5.9e-03 | 4.7 | 5.4 | 7.9e-08 | -0.53 | 0.46 | 0.32 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | CEBPG | 0.16 | 0.08 | enet | 11 | 0.14 | 6.1e-12 | -4.1 | 5.7 | 1.5e-08 | -0.56 | 0.99 | 0.01 | FALSE |
| 4 | METSIM | Adipose | KCTD15 | 0.08 | 0.06 | lasso | 4 | 0.05 | 2.9e-08 | 5.3 | 5.3 | 1.5e-07 | 0.02 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PEPD | 0.08 | 0.04 | lasso | 8 | 0.03 | 2.8e-04 | 6.2 | 6.0 | 2.0e-09 | -0.28 | 0.29 | 0.02 | TRUE |
| 6 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | KCTD15 | 0.25 | 0.05 | lasso | 4 | 0.04 | 3.3e-02 | 6.3 | 6.2 | 5.8e-10 | 0.03 | 0.00 | 0.93 | TRUE |